Basic Information

Insect: Megathymus violae
Gene Symbol: ZNF296
Assembly: GCA_003671415.1
Location: PDGT01000113.1:71138-78987[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0091 0.83 10.8 0.2 3 23 172 192 170 192 0.97

2 15 0.0026 0.24 12.5 2.9 1 23 301 323 301 323 0.98

3 15 2.1e-05 0.0019 19.1 0.9 1 23 329 352 329 352 0.97

4 15 0.57 52 5.2 6.4 1 23 357 380 357 380 0.94

5 15 0.0011 0.1 13.7 2.0 2 23 598 619 597 619 0.97

6 15 0.0027 0.25 12.5 1.3 1 23 625 648 625 648 0.95

7 15 0.55 50 5.2 4.4 1 23 714 736 714 736 0.96

8 15 1.7 1.6e+02 3.7 0.2 1 23 743 765 743 765 0.95

9 15 0.0028 0.25 12.5 3.2 1 23 771 793 771 793 0.95

10 15 0.0012 0.11 13.6 4.8 1 23 799 821 799 821 0.98

11 15 0.06 5.5 8.2 3.1 1 23 830 852 830 852 0.98

12 15 0.00023 0.021 15.8 0.6 2 23 898 919 898 919 0.97

13 15 0.019 1.7 9.9 6.3 1 23 936 958 936 958 0.96

14 15 1.9e-06 0.00017 22.4 0.6 1 23 964 986 964 986 0.98

15 15 1.7e-06 0.00016 22.5 4.0 1 23 992 1015 992 1015 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0091	0.83	10.8	0.2	3	23	172	192	170	192	0.97
2	15	0.0026	0.24	12.5	2.9	1	23	301	323	301	323	0.98
3	15	2.1e-05	0.0019	19.1	0.9	1	23	329	352	329	352	0.97
4	15	0.57	52	5.2	6.4	1	23	357	380	357	380	0.94
5	15	0.0011	0.1	13.7	2.0	2	23	598	619	597	619	0.97
6	15	0.0027	0.25	12.5	1.3	1	23	625	648	625	648	0.95
7	15	0.55	50	5.2	4.4	1	23	714	736	714	736	0.96
8	15	1.7	1.6e+02	3.7	0.2	1	23	743	765	743	765	0.95
9	15	0.0028	0.25	12.5	3.2	1	23	771	793	771	793	0.95
10	15	0.0012	0.11	13.6	4.8	1	23	799	821	799	821	0.98
11	15	0.06	5.5	8.2	3.1	1	23	830	852	830	852	0.98
12	15	0.00023	0.021	15.8	0.6	2	23	898	919	898	919	0.97
13	15	0.019	1.7	9.9	6.3	1	23	936	958	936	958	0.96
14	15	1.9e-06	0.00017	22.4	0.6	1	23	964	986	964	986	0.98
15	15	1.7e-06	0.00016	22.5	4.0	1	23	992	1015	992	1015	0.98

Sequence Information

Coding Sequence: ATGAATCAAAACTTCATTGAAGTTGATCCATTGAGTATATATGATTATCCTTTGGCTTACCATAGCATAAATCAAGAAATTGCTGCAGTTAATGCAATAGAAAATGGTCCGTATAACAAAAGCAATCCAAAAAGGAATATACAAAATAGTCAATTCAATAAAAACAATCAGGAAGTCCCTCTAGCTGATCTACAGAATGATCAGAATAACGAGAATAGTAAATTGGAATCATTAAATGATATATCACAGACTGAACATACTAAGTTGCCTGACAGTAATGTGAAACATGAATGTAATGATGCAGGATATAGTAACGATATGGTTAAAAACTTAATGAATAATTTGTCTCTTAATTTAAATAACAATCTAAATGGCGAAATCTTAAGTAGTCAGAAAACTGAAAATATTGTTATTGATACAAAACCATTTGACAAAGTGAAACGTAAAGTGAAAAAAGAAAGAAGTACTTATTGGTCAGAAAAGATAACAGAGAAAGATTTTCCATTTTATGGATGTGCTGTTTGCAATATTTGCTATGTAGATTTAACAGAATTGGATAAACATATTGCTACACATAAAGACAGAACAACAAGTTACGACTTGAGAGTCAAGAATCAGCTGAAACGGAAAAAATTAAAAAAGGAAAAGAAAAAACTGAAGAAACTAAGCAAAGAAATAAAAAAAGAAAATCATTTAATTGACATAGAAATTAAACCGGAAGACGGGTATATAGGTAATGAAAAAGCTTCAGACTTTCAGAATAGAGACAATGAAATGCCAAATAATATAAATGCTGACAAAAAGGAGTCAGACACAAATGGAAGTACAAACAAGAAACGTGATGTTGATAAACAATCAAAGGTTGAAAATAACCAGGAGTTAATGAATTTGCAGAAAATTTTCAAATGTTTTGCATGTCAGAAACAATTCACCCTAAGTTACTACCTCAAGTTACATGTAAGATCACACACTGATGAAAAACCCTATACGTGTCCCACATGTGGACAGTCCTTTATAACTGCGAGCAAGCTTGGGAGGCACAACAAGAGATTCCACCTGCAGATAAAGTTTCAATGCAGGATATGTTATAGATTTTATTCAAGATTCGAATGCCTGACTACACATTTTGACAGAAAACATCCCGATGACAAAATTGAAGGCGAACCATATGATTATAATGCGATATTACCATATCTAAAAGAATTGGAAGAAGAACTAAAACGGAAGTCAGAAGAAACTAAGCCGAAGAAAGAAGAATCTTGGCCTGACGGTTGGGATCGAACCAATGGTGTAAATGAATCGGGCTTAATGGATTTTAAAAATGAACCTGGAAGTAATGAAGCGGGCGGGAATAATTTTATGTGTCAGAACGGAATCGGCTCGATGGACGAAAACGAAATATACTTAGGCTCAAGCGACATGTCGCTTGATACTCATGAACGAGTCTTGGCGAAACCGATAGAGATAATAATTGAAGAAATGAAGCCAGACGTCGAACATGCATCAGAGAAAATTGAGGTGGAAGTTAAGACCGAGGTGTTTGATCAATTTGAAGATGAGAATGGGAAGGCCGACAGCGATGATGACGCGAAGGTGAAAAATGAAAGGTATCTGAAAATTAGTAGGGTACGATTATGTTGTGGAGTTCTGGTCTGTGTGAATTTTGTTTGTGTTTGTCCTAGAGGCCTGTTGTGTGGATCAGACGATGAATACTTCCCGGACAACACGTGGGTGTCCACTAAGGACGAGAGTCCCCCACCCGCGGACGTGGAGCCAGACACGGACCCCCTGACGTGTCGCGTGTGCAAGAAGAAAATCAGCTCCACCTCCTACATGAAGATCCACATGCGGACTCACACCGGGGAGAAGCCGTTCAAATGCTACATATGCAACGCCGGGTTTATCACCAGCAGCAAAATGCATCGGCATGTTCTGAACGTGCATACCATGGTGCATGATGATGGTGCGGTAGACATAAAGAAAGAAGAATCAACTGACAAAGAAGTAAAACCGAAGAAGGAAAAGTTGGACGAACGAGACAAAAAGTCGAAGGATGCATCGGTCGAAAAAGTGAAAGTAGAGAAGAAATCAAAGAAGACCGGTGTGGAGAAGAAAAAGAAGAAATACCAGAAACGGCCGCACGCCTGCGAGTTCTGCAACCAACGGTTTCTACATTTGGAGACGTTACAGGTACATAAAAAGTCTCACGAAGGCCAACCGATAGTGTACAAATGTAAGTTCTGTCTGGTGGAGATGGAAGATGAGGCATCGCTGAAGACCCACGAAGAGACTCATGGCGGACCGAAGCCCTACCTCTGCACTATATGCGGGAAGGTGTACAAGAAGAAGGAAACTATGGTGTACCATCGAAAACACCATAAACCGGACAACATCTACGTTTGCTCCGTTTGCTCCAAAACGTTCAGTGTCAAGTGTAAATTCCAACGTCACTCGCTCACCCACCGCCGCGAACAGTACACACTGCGGTACGAGTGTCCGGTCTGCGCGCACATGTTCCACACCAAGTACCACGTGGGGATGCATCTCGCCACCCATCAGCGGGAGGGACTAATCGTGGAGCAGAATCGCAACGAAATCCTTGCTATGGTGCTTCAAAACGCCAGAAAGGTGCCAAAGAAGGACCCTTCGGGCATCACTGACACATTGCTACCGGCGGACGAGCGAAGCCGCGTCTGCAACATATGCGGCGAGGTCTTTCAACACTTCTACTACCTGGAGGAGCATCTCAAGAATCACGCTTCGAAATTGGCGATCGAAGATGAGGACAAACCGGAAGACAAGAAACACGTGTGCCAAGTTTGCAATAAAAGCTTTAAGTTACACTACTATTTAAAGCTGCACAGCTTCACTCACACCAAGGAGAAGCCGTATATATGTCAGCAGTGTGGCAAAGGATTCATCACACGTGGCAAGTTAAAAAGGCATTTGGAAACTCATGCCGGTTTGAAGAAGTTCCAATGTCACGTGTGTTACAAGTTCTTTACCAGACCGAGCTACCTCCGGACTCACGTGAGAACGATTCACGGGACGCAGGACTACAATTTCAGGTTGGCGCAGAATCTAGGAATGACGTATCCCAGTCAGCACGTGTGA
Protein Sequence: MNQNFIEVDPLSIYDYPLAYHSINQEIAAVNAIENGPYNKSNPKRNIQNSQFNKNNQEVPLADLQNDQNNENSKLESLNDISQTEHTKLPDSNVKHECNDAGYSNDMVKNLMNNLSLNLNNNLNGEILSSQKTENIVIDTKPFDKVKRKVKKERSTYWSEKITEKDFPFYGCAVCNICYVDLTELDKHIATHKDRTTSYDLRVKNQLKRKKLKKEKKKLKKLSKEIKKENHLIDIEIKPEDGYIGNEKASDFQNRDNEMPNNINADKKESDTNGSTNKKRDVDKQSKVENNQELMNLQKIFKCFACQKQFTLSYYLKLHVRSHTDEKPYTCPTCGQSFITASKLGRHNKRFHLQIKFQCRICYRFYSRFECLTTHFDRKHPDDKIEGEPYDYNAILPYLKELEEELKRKSEETKPKKEESWPDGWDRTNGVNESGLMDFKNEPGSNEAGGNNFMCQNGIGSMDENEIYLGSSDMSLDTHERVLAKPIEIIIEEMKPDVEHASEKIEVEVKTEVFDQFEDENGKADSDDDAKVKNERYLKISRVRLCCGVLVCVNFVCVCPRGLLCGSDDEYFPDNTWVSTKDESPPPADVEPDTDPLTCRVCKKKISSTSYMKIHMRTHTGEKPFKCYICNAGFITSSKMHRHVLNVHTMVHDDGAVDIKKEESTDKEVKPKKEKLDERDKKSKDASVEKVKVEKKSKKTGVEKKKKKYQKRPHACEFCNQRFLHLETLQVHKKSHEGQPIVYKCKFCLVEMEDEASLKTHEETHGGPKPYLCTICGKVYKKKETMVYHRKHHKPDNIYVCSVCSKTFSVKCKFQRHSLTHRREQYTLRYECPVCAHMFHTKYHVGMHLATHQREGLIVEQNRNEILAMVLQNARKVPKKDPSGITDTLLPADERSRVCNICGEVFQHFYYLEEHLKNHASKLAIEDEDKPEDKKHVCQVCNKSFKLHYYLKLHSFTHTKEKPYICQQCGKGFITRGKLKRHLETHAGLKKFQCHVCYKFFTRPSYLRTHVRTIHGTQDYNFRLAQNLGMTYPSQHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00970633; iTF_01438276; iTF_00887629; iTF_00795911;
90% Identity: iTF_00970633;
80% Identity: iTF_00970633;