Mvio002709.1
Basic Information
- Insect
- Megathymus violae
- Gene Symbol
- -
- Assembly
- GCA_003671415.1
- Location
- PDGT01000006.1:10323856-10341643[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.007 0.64 11.2 1.5 1 23 323 345 323 345 0.98 2 11 0.42 38 5.6 2.8 1 21 352 372 352 374 0.95 3 11 0.18 16 6.8 0.5 1 23 378 401 378 401 0.90 4 11 2e-06 0.00018 22.4 0.7 3 23 409 430 407 430 0.94 5 11 0.00019 0.018 16.1 0.8 2 23 437 459 436 459 0.94 6 11 0.0026 0.24 12.5 0.2 2 23 473 494 472 494 0.92 7 11 2.1e-05 0.0019 19.1 0.2 1 21 500 520 500 525 0.93 8 11 0.00051 0.047 14.8 0.2 2 23 534 556 533 556 0.95 9 11 0.0001 0.0095 16.9 0.5 1 23 562 585 562 585 0.97 10 11 2.3e-07 2.1e-05 25.3 0.5 1 23 594 616 594 616 0.98 11 11 0.028 2.5 9.3 0.0 1 23 622 645 622 645 0.96
Sequence Information
- Coding Sequence
- ATGAGCAGACGCATGATATCGGCCACACGGAGCAGTGGGGAACGTGATGTGGGCGAGAGGGCCACGAAGGAATCGAACCAGGCAGACGGCGCAAACACGCAGCCGATCCCACCGCTCGAAATCTTATCGGACACATCAGATAAACGTAATATTGATAATAAACCCTTACGGCGAACGGCGGCTGAGCTAGCTCGTGTTAACATAAAACTACTAAATCATGAAAAGCAAACGGCAAGAACCCACTCGCAGGTAGTATGTCTGACGAGTACCACACTGGATCCTGTGGAAGTGGGCAGCGACAAATGTAAAAATGTCCTCTTGAAGGTCGAGGTGAAAAATGAGAATGGACTCTCGAATCATTCGGAAGGCGAGCTCGTTGACGATAACAATGATTTTCAAGACTCTTCAGTAACAGAAGAAGATGATTTCGCGCTGAAAGATTTGTTGAAACAAAAATTAGATGTCGATGGACTAGCTATCAATTTGAGAAGACCCGTGAAAAGAGGAAAGGTGGAGAGGAAGGTTGGTAAAAAGAAAAAACACCGTCGAAGTAAACAAGGACGTCTCGGGGCGCCGCCGCCCGCCGCCGCGGCGTCTTCCTCCCCGGTCATACTCATCGTCACAGCGCCACCGTACTTGAAAGAGATCGATTCCGAGCCAATCTTTATACAGAAAATAAAATCAAAATCGGGACATAAACGAAGGAGTTATTTGTCGATATTTGCAGTGATAGATGTTGAAAACGATCGTTCTGAACGAGACGATCCGTCGAGCGATTCGGCGAAAGACGAAACAGTCGTAGGAAACTTAAAAACGGCAGCTTTCGATAAAAGTCAAATTCGGAAATCAAAAGGCAACGATACAAAAAAAGACGTGTGTAAGACCAAAACGGTGTACATAACGAGGGACCGGTGCATGGAGGAGCGAGCCGAGATGGCCGCGGACAAGAAGTATCTCAACTGTACATACAAATGTGCGGACTGCGTCAAGGGGTTCCACTTGAGGGAGAGCTACGACAGGCACATGGAGAGCCACCAGGAGGCAATGGGAAATTACGAATGCGACATTTGCAAGCAGAGAATGGATTCGAAAGTGAAGCTGGTACGTCACAAGAGGTGTCACGAGGTCCGATATAAATGCACCGTCTGTGGGTTGACCAGAATAAACCGGTTGACCATCCGGGAGCATTACAACGCGTTCCACTTGAAGCTATATTCGTACGGCTGTCCGCACTGCCCCAAGGCGTTCAAACGGCAGGTGTCGCTGCGGAAGCATATAGCGTACCTGCACGGGAGCAAAGTGCGCGTCAAGTGTCAACACTGCCAGAAAATGTACGCCAACAAGGAGGTGCTGAGGGCGCACATGATAGCGAGACACCCGCGCGAGGTGTCCGCCGGGGCGGCGCCACGCCGGTGCGTGTGCCGCGAGTGCGGCGCGGCGTTCGCGGCGCCGTCGCAGTTGCGGAACCACAGCGTGAAGCACTCGCTCGCCAGGGACTACTACTGCGTCGAGTGCGACAAAAGTTTCAAGTCGGAGGCGGCGTTCAAGCGGCACGTGAAGGTCGCCGCGCCGCACGTCGACTACGCGGACCTGCCACTACCCTGCGGCCGCTGCGACAAGCGGTTCGCGATCCGGCGCGACCTGGAGCGGCACGTGAACCGCGTGCACCTCAACATCAAACCGTTCCAGTGCGACAGGTGCGACAGGGCCTACGTCAACAACTGGTCCCTGAACGAACACAAGCGGTACGTCCACGACGGACACAAACGACCCCTGAAGTACCCGTGCTCCATGTGCGACAAAGTGTTTGACCGTAACCAAACGCTGAAGGCGCACGTCCGCACGCACACGGGCGAGCGGCCGTTCCCGTGCGCGCGCTGCGCCGCGCGGTTCGCGCAGAGCAGCGCGCTCGGCACGCACGTGCGGCTCGTGCACCTGCGGCTGGCGCGCGACGGCACGCCGCGGCGCGCGCGCGACCATTAG
- Protein Sequence
- MSRRMISATRSSGERDVGERATKESNQADGANTQPIPPLEILSDTSDKRNIDNKPLRRTAAELARVNIKLLNHEKQTARTHSQVVCLTSTTLDPVEVGSDKCKNVLLKVEVKNENGLSNHSEGELVDDNNDFQDSSVTEEDDFALKDLLKQKLDVDGLAINLRRPVKRGKVERKVGKKKKHRRSKQGRLGAPPPAAAASSSPVILIVTAPPYLKEIDSEPIFIQKIKSKSGHKRRSYLSIFAVIDVENDRSERDDPSSDSAKDETVVGNLKTAAFDKSQIRKSKGNDTKKDVCKTKTVYITRDRCMEERAEMAADKKYLNCTYKCADCVKGFHLRESYDRHMESHQEAMGNYECDICKQRMDSKVKLVRHKRCHEVRYKCTVCGLTRINRLTIREHYNAFHLKLYSYGCPHCPKAFKRQVSLRKHIAYLHGSKVRVKCQHCQKMYANKEVLRAHMIARHPREVSAGAAPRRCVCRECGAAFAAPSQLRNHSVKHSLARDYYCVECDKSFKSEAAFKRHVKVAAPHVDYADLPLPCGRCDKRFAIRRDLERHVNRVHLNIKPFQCDRCDRAYVNNWSLNEHKRYVHDGHKRPLKYPCSMCDKVFDRNQTLKAHVRTHTGERPFPCARCAARFAQSSALGTHVRLVHLRLARDGTPRRARDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00970614;
- 90% Identity
- iTF_00970614;
- 80% Identity
- -