Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000127.1:259842-263901[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 4.3e-06 0.00039 21.3 0.6 1 23 166 188 166 188 0.97

2 12 7.6e-06 0.00069 20.5 1.6 1 23 194 217 194 217 0.97

3 12 0.00011 0.01 16.8 0.3 1 23 223 245 223 245 0.97

4 12 1.3e-05 0.0012 19.7 2.2 1 23 251 273 251 273 0.99

5 12 5.5e-06 0.0005 20.9 3.3 1 23 279 301 279 301 0.99

6 12 4.6e-07 4.2e-05 24.3 1.0 1 23 307 330 307 330 0.96

7 12 5.7e-05 0.0052 17.8 3.9 1 23 336 358 336 358 0.97

8 12 1.2e-05 0.0011 19.9 0.8 1 23 364 386 364 386 0.98

9 12 9.7e-05 0.0088 17.0 2.2 1 23 392 414 392 414 0.99

10 12 6e-07 5.4e-05 24.0 2.4 1 23 420 442 420 442 0.98

11 12 2e-07 1.8e-05 25.5 0.8 1 23 448 470 448 470 0.98

12 12 0.13 12 7.2 3.8 2 23 476 494 475 494 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	4.3e-06	0.00039	21.3	0.6	1	23	166	188	166	188	0.97
2	12	7.6e-06	0.00069	20.5	1.6	1	23	194	217	194	217	0.97
3	12	0.00011	0.01	16.8	0.3	1	23	223	245	223	245	0.97
4	12	1.3e-05	0.0012	19.7	2.2	1	23	251	273	251	273	0.99
5	12	5.5e-06	0.0005	20.9	3.3	1	23	279	301	279	301	0.99
6	12	4.6e-07	4.2e-05	24.3	1.0	1	23	307	330	307	330	0.96
7	12	5.7e-05	0.0052	17.8	3.9	1	23	336	358	336	358	0.97
8	12	1.2e-05	0.0011	19.9	0.8	1	23	364	386	364	386	0.98
9	12	9.7e-05	0.0088	17.0	2.2	1	23	392	414	392	414	0.99
10	12	6e-07	5.4e-05	24.0	2.4	1	23	420	442	420	442	0.98
11	12	2e-07	1.8e-05	25.5	0.8	1	23	448	470	448	470	0.98
12	12	0.13	12	7.2	3.8	2	23	476	494	475	494	0.88

Sequence Information

Coding Sequence: ATGGCTGAAAATTTGAACTTAAATAAGATATGTCGTTGCTGCCATACTCAGGGAGTATTTAAGAGCCTTACGACCCCATACACCCAAGAAGGTAAAGAAGAAATATATTCAAATATGCTGAAACAAACTTTCGATTTAGTGTTGACAACATTACAGGATGCCAGTGACACAACATCTATGATATGCAATACATGTATAAGTAGGCTCCGAGATGCCAATCAGTTCAAACAACAGGTGTTGTTGTGTGAACAAACATTGAAGAAATTTTATAATCATTTTAACCAAAAAAGTACTACAGTTAGGGCAGTCAAAGAAGAACTTGAAATCTGCATTGATGAGGATAAAACTCCATTGGGGATCTTTACACAAGCAATGGATGTGGATGACCAGCCGCTTTCGGTTTTAAGGAGTCAGGATAACCACGAGGAGTGGGCGCTGCCTGATAATAGTGGTGATGAAGAAACTAAACCATTAACCCAAATTAAAACGAAGAAATTCGCCTGCACCATATGTTTCAAACAGTTCACATACAACGGATCACTGGAAGTTCACATGAAAATTCATACAGGGCAAAAACCCTATCCGTGTCGTATTTGCAACGAACGATTTTCTCACAACAAGGAACTCATCAAGCATATATCTTCCAGCCATTCGGATAACGGAAAGTTTCCTTGCAAAGTTTGCGCGAAAATATTCGACAAGGCCAGGCAGTTGAAGAATCATTTAAGCGTACACTTCGATAGCGACCAGTTCAAATGTTCGGAGTGTAATAAGCTGTTCCAAAGACGTAAAGGCCTAAAAGAACACATGAAAATACATTCAGGGGAACGGAACTTTAAATGCAGTATTTGCAGTAAATCATTTGGACACAATCAAACTTTGAAATCCCATATTCTGACCCACACTGGAGAAAAGCCTTATGTATGTGATGTCTGTGGCAGGAGATTTCCTCAACGGACACATTTAAAACGACATATCTACATAATACACACGGGGGTCAAGCCTCATTCGTGTAAAGTCTGCCAGAAGCAATTCTCAAGCAAAAGTTATCTGTCCATACATGAGAGACAACATACCGGAGTCAAACCTTACTCTTGTGAGGTTTGCAAGAAAGATTTTACAGCATACACAACACTAAAAGTCCACATGAGGGTTCATACCGGTCAAAAGCCATACTCCTGCAGTTTCTGTGACAGGCAATTCGCCCAAATGTCAAGCTTTAAGCTTCACGAAAGAACGCACACTGGAGAAAGACCATTTTGTTGCAAAATTTGTAAAAAGATGTTTGCTGACAACGGTTACTTGAAGATTCACATGAGAGTTCACACTGGAGAGAAGCCTTATAACTGTGAAGTGTGTGATAAGGCTTTCAGGGAGACAGGTCAATTAAAACGACACATGAAAACACATAGCCAGATTAAATTGACGTGTAAAATTTGTAACAAACAAATTGGGAACTTAACGAGGCATATGAGAATCCATTCCGTTGAAAGGCATAAATGTACTGCGCGGGTGAAAAAGAAACAATTTTAG
Protein Sequence: MAENLNLNKICRCCHTQGVFKSLTTPYTQEGKEEIYSNMLKQTFDLVLTTLQDASDTTSMICNTCISRLRDANQFKQQVLLCEQTLKKFYNHFNQKSTTVRAVKEELEICIDEDKTPLGIFTQAMDVDDQPLSVLRSQDNHEEWALPDNSGDEETKPLTQIKTKKFACTICFKQFTYNGSLEVHMKIHTGQKPYPCRICNERFSHNKELIKHISSSHSDNGKFPCKVCAKIFDKARQLKNHLSVHFDSDQFKCSECNKLFQRRKGLKEHMKIHSGERNFKCSICSKSFGHNQTLKSHILTHTGEKPYVCDVCGRRFPQRTHLKRHIYIIHTGVKPHSCKVCQKQFSSKSYLSIHERQHTGVKPYSCEVCKKDFTAYTTLKVHMRVHTGQKPYSCSFCDRQFAQMSSFKLHERTHTGERPFCCKICKKMFADNGYLKIHMRVHTGEKPYNCEVCDKAFRETGQLKRHMKTHSQIKLTCKICNKQIGNLTRHMRIHSVERHKCTARVKKKQF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01438230;
90% Identity: iTF_00970591;
80% Identity: iTF_00970591;