Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:493929-501547[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 37 0.084 7.7 7.8 0.3 1 23 52 74 52 74 0.95

2 37 0.23 21 6.4 1.9 2 23 102 124 101 124 0.93

3 37 0.11 10 7.4 1.1 2 23 145 167 144 167 0.94

4 37 0.058 5.3 8.3 5.7 1 23 172 194 172 195 0.96

5 37 0.27 25 6.2 1.3 1 23 199 222 199 222 0.91

6 37 0.046 4.1 8.6 2.2 2 23 225 247 224 247 0.95

7 37 0.65 59 5.0 0.8 2 20 253 271 252 273 0.92

8 37 0.014 1.3 10.2 2.9 1 23 321 344 321 344 0.96

9 37 0.00017 0.015 16.3 0.3 1 23 416 439 416 439 0.92

10 37 5.4e-05 0.005 17.8 0.3 1 23 444 467 444 467 0.95

11 37 0.00014 0.013 16.6 3.2 1 23 472 495 472 495 0.94

12 37 0.0023 0.21 12.7 0.5 2 23 501 523 500 523 0.93

13 37 0.025 2.3 9.4 1.0 1 17 527 543 527 544 0.90

14 37 0.00094 0.085 13.9 1.5 1 23 585 607 585 607 0.96

15 37 0.024 2.2 9.5 0.0 3 23 636 657 634 657 0.91

16 37 0.0049 0.45 11.7 0.6 3 23 679 700 678 700 0.98

17 37 3.2e-05 0.0029 18.6 0.7 1 23 705 728 705 728 0.96

18 37 0.0087 0.8 10.9 0.4 1 23 733 756 733 756 0.98

19 37 0.069 6.3 8.0 3.6 2 23 759 781 759 781 0.96

20 37 0.26 23 6.3 4.0 2 22 788 808 787 808 0.96

21 37 0.013 1.2 10.4 2.7 1 23 862 885 862 885 0.93

22 37 0.0024 0.22 12.6 0.3 2 23 958 980 957 980 0.94

23 37 2.2e-05 0.002 19.0 0.7 3 23 987 1008 986 1008 0.94

24 37 0.0088 0.81 10.9 3.6 2 23 1013 1035 1012 1035 0.93

25 37 0.0026 0.24 12.5 2.7 1 23 1040 1063 1040 1063 0.95

26 37 1.8e-05 0.0016 19.4 4.9 1 23 1067 1090 1067 1090 0.97

27 37 0.00056 0.051 14.6 0.3 2 23 1097 1118 1096 1118 0.96

28 37 0.00012 0.011 16.7 1.6 1 23 1124 1146 1124 1146 0.98

29 37 0.59 53 5.1 0.1 1 23 1199 1222 1199 1222 0.96

30 37 0.03 2.7 9.2 0.1 2 23 1253 1275 1252 1275 0.94

31 37 0.0049 0.45 11.7 1.5 1 23 1325 1348 1325 1348 0.95

32 37 0.069 6.3 8.1 1.1 1 23 1353 1376 1353 1376 0.94

33 37 0.0072 0.66 11.1 1.0 2 23 1382 1404 1381 1404 0.91

34 37 0.00034 0.031 15.3 0.1 2 23 1412 1434 1411 1434 0.97

35 37 0.076 6.9 7.9 0.1 2 23 1441 1462 1440 1462 0.96

36 37 2.8e-06 0.00026 21.9 1.3 1 23 1468 1490 1468 1490 0.94

37 37 2.9e-05 0.0026 18.7 3.1 1 23 1496 1519 1496 1519 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	37	0.084	7.7	7.8	0.3	1	23	52	74	52	74	0.95
2	37	0.23	21	6.4	1.9	2	23	102	124	101	124	0.93
3	37	0.11	10	7.4	1.1	2	23	145	167	144	167	0.94
4	37	0.058	5.3	8.3	5.7	1	23	172	194	172	195	0.96
5	37	0.27	25	6.2	1.3	1	23	199	222	199	222	0.91
6	37	0.046	4.1	8.6	2.2	2	23	225	247	224	247	0.95
7	37	0.65	59	5.0	0.8	2	20	253	271	252	273	0.92
8	37	0.014	1.3	10.2	2.9	1	23	321	344	321	344	0.96
9	37	0.00017	0.015	16.3	0.3	1	23	416	439	416	439	0.92
10	37	5.4e-05	0.005	17.8	0.3	1	23	444	467	444	467	0.95
11	37	0.00014	0.013	16.6	3.2	1	23	472	495	472	495	0.94
12	37	0.0023	0.21	12.7	0.5	2	23	501	523	500	523	0.93
13	37	0.025	2.3	9.4	1.0	1	17	527	543	527	544	0.90
14	37	0.00094	0.085	13.9	1.5	1	23	585	607	585	607	0.96
15	37	0.024	2.2	9.5	0.0	3	23	636	657	634	657	0.91
16	37	0.0049	0.45	11.7	0.6	3	23	679	700	678	700	0.98
17	37	3.2e-05	0.0029	18.6	0.7	1	23	705	728	705	728	0.96
18	37	0.0087	0.8	10.9	0.4	1	23	733	756	733	756	0.98
19	37	0.069	6.3	8.0	3.6	2	23	759	781	759	781	0.96
20	37	0.26	23	6.3	4.0	2	22	788	808	787	808	0.96
21	37	0.013	1.2	10.4	2.7	1	23	862	885	862	885	0.93
22	37	0.0024	0.22	12.6	0.3	2	23	958	980	957	980	0.94
23	37	2.2e-05	0.002	19.0	0.7	3	23	987	1008	986	1008	0.94
24	37	0.0088	0.81	10.9	3.6	2	23	1013	1035	1012	1035	0.93
25	37	0.0026	0.24	12.5	2.7	1	23	1040	1063	1040	1063	0.95
26	37	1.8e-05	0.0016	19.4	4.9	1	23	1067	1090	1067	1090	0.97
27	37	0.00056	0.051	14.6	0.3	2	23	1097	1118	1096	1118	0.96
28	37	0.00012	0.011	16.7	1.6	1	23	1124	1146	1124	1146	0.98
29	37	0.59	53	5.1	0.1	1	23	1199	1222	1199	1222	0.96
30	37	0.03	2.7	9.2	0.1	2	23	1253	1275	1252	1275	0.94
31	37	0.0049	0.45	11.7	1.5	1	23	1325	1348	1325	1348	0.95
32	37	0.069	6.3	8.1	1.1	1	23	1353	1376	1353	1376	0.94
33	37	0.0072	0.66	11.1	1.0	2	23	1382	1404	1381	1404	0.91
34	37	0.00034	0.031	15.3	0.1	2	23	1412	1434	1411	1434	0.97
35	37	0.076	6.9	7.9	0.1	2	23	1441	1462	1440	1462	0.96
36	37	2.8e-06	0.00026	21.9	1.3	1	23	1468	1490	1468	1490	0.94
37	37	2.9e-05	0.0026	18.7	3.1	1	23	1496	1519	1496	1519	0.98

Sequence Information

Coding Sequence: ATGGAAATCTCATTCGTCCAGATTTTCTCACAATGTTCATTTTGTGATAAAAATGTTATCGGCGCGGCACAGACGCAAAGTTTTAATAGAAGAAGGAATCTACAGATATTGTTCAACAACACGACCTTGTGTCCTTTTAAATGGCGGGGCAAATACCTGTGTTTTTATTGTGGAGAGGATATGCCAAACTACGAAGAACTAAAGAAACATACAAAAGGGCATGGCCCTTGTACCGACAGAGATAGAGCTATTAGATTAGTTAAAGCCGCTGATGCTGAAGTGAAAATTGACGTTTCAGACATCACATGCGAGATATGTAAAGAATGTTTTGTCAGCTTTGATGAAATTGTCGGTCATTTGAAACACAAACACGAATTGCCTTACGATACTGGTGTCAAGCTTTCTTTGGTTATATACCGTCTTATAGATCTGCAATGTTTATTCTGTGAAGAGAAATTCAATTACTTTAATAAACTTATCAAACACGTCAACAACATGCATCCTAGTGAAAGTTTCGAATGTTGTAAGTGTCTACAGATGTTCAATAAGAAACGGGACTTAGATGCTCATACGCGGATGCATCATAAAAAAGACTATAGATGTCTTAAATGTTCTGTAACATTCGCTTCATATGCCGTTTTCAAGAAACACAATTTGAATTCTCATATCTCTACGTGTAATGTTTGTTTCAAAAATTTTGCATCCTTAAAGAAACGCTTGAAACACATGAAGCAAGAACATGCAAATGATATGCTCCAATGCGGTTTTTGCTCAAAAACAATGAGTACAAAACAAAGCTTTTTACGTCACGCGACCAAATGTAACTTACGAATTAACAGCTCTGAAAAAGTAATCGTTGACGATGAGGATAGAAAGCCGTCTGTCATTCAAATAAGAAATAATGTTGCTTGTGTATTAAATATGTCAACTGCCATTCCTTTCAAGTACTTTATGAGTAGATTTAGATGTTTCTACTGTCCTAAAGATTTTTATGAATGCACTGATTTAAGAGAACACACGGTGACAGAACACCCGCATTGTGACATTAAGCTTAAGAGCATGAAATTACGTAACAGACATGACGGGTGTATAAAAATAGATATCTCATCTCTGTCTTGCAAGTTATGTTTTGAACCAATACACGATTTAGAGGCCTTAATAGATCATCTTATTTTCAACCATAAGGCGAACTATGATAAGTCCATCGACTGTAACATGCAGCCTTATAGATTAATTAAAGACAATTTCTCGTGTCCTCTATGTGGTGAAGTTTATCGATACTTTAGTTCGTTGCTAAGACATATCGGTAATTTCCATACGGACAATAAGTATATTTGTGTTTACTGCGGCAAGTCATTGAGGAATGTTTCGAATTTAAGGGCACATGTTTCCAGTAAGCATAATACTGCCGTTCATAAATGCAGTAAATGTGATATGGAGTTTAATTCTAATAGTCATTTACAAACTCACTTAGGCAGCGCACACGGGATGAAGGTGATTCAATGTTCGGAATGTCAAGAAAAATTTATATCCAACTATAGAATGCAGAGGCACATGGTCAATGTGCACAGATCTGGACATAAGTGCACATTTTGCGGGAAGTTATTTACTAGAAACTCGCTAATGAAAAATTTCTTTGCAGATGAAATCGCGCATAGCAAGTACGAGAACTACACCTCTGAGAGAAGGAGGAAAAATTTGAAAATCCTCTTCAACAATACATCTATTATACCGTTTAAATGGCGTGGCAAGTACTTGTGCTTTTACTGCGGTAAGAATTACGCAGATTATCCTGAATTTAAAAAGCATACTAAATCTCACGGTCTTTGTACCACTAAGGACTATTCTCTTAAACTTGTCAAAGGGTCTCACAATGAAATAAAAATAGATATTTCAGATATGAACTGTGAAATTTGCAATGAACCATTTACCTCCCTAGATGAGATAATCAGTCATCTAATAGGAAAACATAGTCTGGAATATGACAAATCTATTGTTATTGCTTACCAAGAATATCTCTTGGCAGATTCACTATGCCAATTTTGTGGAGAACATTTTGAATATTTTGGTTATCTTATCACCCATATAAACACAATTCATCCACAAAACTGTTTCATGTGTGATGACTGCGGACTTACCTTCAATAAGAAGAGAGATTTGGCGTATCATATAAGGCAAAATCACCGTAGAGGCGGCTACCCTTGTGACGAGTGTTCAGATGTATTTGAATCTCAAGGATTGATGCGAAAGCATAAAAATACCTTTCATTTTAGAAAGTGCAAATCCTGCCATTCTAGGTTTGCGTCATTCACTCTTCTCCAGAAACATATCAAGTTAGAACATTCTGTTACTGCCATTAAGAAATGTCCACATTGCGCAAAAGAATGTCACTCAAGACAGGGTCTGATGCAGCACTTACGGACTTGTAAAGTCAAAATGATTGTTAAAAGAGACAAGCCAACTACTTTTCCATCAAGAATGTTATTAATGCCTAGAAAGACGCAGAACATATCGCAAATTCGTCAGAATATTGTATGTGTACTGAATATGTCAACAGTAATACCGTTTAAGTTCTTTGCAAAATTTTCTTGCTTTCATTGCTCGAAAAAATTTACTGAATTCGAAGAATTAAAGGAGCACACGGCGTTAGAGCATCCTGTTTGTGACATGAAATCTAAATGCATCATAAAGTGTAAAGGAGAACGTACATGCGTGAAAATTGACGTGACGTCATTAGCGTGTAAAATCTGCTGTCAGTCGATGGAAGATCTAGATGCTTTGATCGATCATTTAATTAGTAAGCACAAAGCAAATTACGACAAGTCGTTGACCGAATGTTTTGAGCCTTTTAAGTTAGTTAAAGACAATATCCCCTGCCCTCACTGTTCGAACATGTTCAGATATTTCGCTACCCTTATTAGGCATATCAACGCAGAACATTGTAACAGCAAAAGGATATGTGATTTTTGTGGTCGATGTTTTAAAAATGCTGCCAATTTAAACGTCCACATTATCTATACGCATACTGGCTCATGCGAATGCGACATTTGTGGTCTTAAGTTCAAGAATCAGTGGTGTTTGGGTCGACACAAAGCAAAGAGTCACGACGCAAAAGATTTTAAATGTCCCAAATGTCCTGAACAGTTTCAGTCTCAATATCACAAGCAGAAACACTTGATCCAAGTTCATGATATCGGACACAAGTGCAGCTACTGCGGACGCATGTTTACGCGAAACTCATTCATGAAAGATCATATACGAAGGACGCATCTGAAAGAGAAGAACGTGCCATGTTCCGTTTGCAATGAGAAATTCTTCGATAACTATTTGTTGAAACTTCACATGGTGAAACACGATGGAGAAAGAAAGTTCTCATGCAGTGTCTGTAGCAAGACCTTTTTGAGGAGAAGCAATTTGAGTTCTCATATGGATATGCACAAAAAATATGGGCACGTTCAAGGTGCCAAATACAATTCGGTGGAGGATAAATATAAGAAACGGGAATTGGCACGTAAGCTATTGTTGAAACGACGCAATGTCGAATATGTGTTGCAGTATGGCAACGTAACACCCTTTATGTGGTACAAGGGTAGATATAGATGTTTTTACTGCGCGGAGCCCATGAAAGATCCCGTGCTGTTAAGAGAACATACGGCCAAAGTGCACCAATTCGCTAATTTAGAGCTGGTAGTACACGATAGGACGAAGAATAATAGAAACAGAGATGCAGCAGTGAAAATAGACGTTACGGATATTTCCTGTAAGCTTTGTCCTCAAGCGGTGAACAGTTTAGAACAATTAATCCATCATTTGATCATAGCTCACGATGCGGAGTATGATGTGAGTGTACCAAACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAACACCACTTGGCTCACGACTACATTTGCGATGTTTGCGGAACTAGTTTCCAAGGTGAAAATCACCTAAAAATGCATAACAGATATTATCACAGGGAAGGCGGTTACACATGTGAACACTGTGGGCTTAGCTTGGCTACGTTGTCAAAGAAGACACTTCATGAAAAAAATGTACATATGATAAACCTTTCCACGTGTCCTCATTGCCCCGAAACGTTCAAAAGTCCATACTTTAAGAAACTCCATTTGGCTAATGTGCACGGAGTTGAGGAATTGAAAATCAAGTGCCCATACTGTCCGAAAGTCTATCCGCAGGAAAGCATCATGTCACGTCATATGAGGCGAGTGCATTTACGAGAGAAAAACGTTGAATGCGAGGTCTGTGGAGACAAATTCTTCGGGCCTTACGATGTGAAATTACATATGTTAAAACACAATGGAGATAAAAAATTCGTTTGCACAGTTTGCGGCAAGAAATTTTCTAAGAAAAGCAACTTGAACTCACATTTCGTTATACATACAGGAAGCAAGAAGTATTCGTGTAAAATTTGCAATAAAGACTTTGCCCATCGTCCAAATCTGAGAATTCATTTCAGGACTAGACATCCTGATTATGAGACTAGGTTTGTGGTAGAAGAGAGCACCGGAATTATTGACGAAGTTGATGATTCGGAAATAGTGCAGATGGATTTTGTTAGGGATGAACTCGAAGGAGCGGAGTTGACCGGACAATATATTGATTAG
Protein Sequence: MEISFVQIFSQCSFCDKNVIGAAQTQSFNRRRNLQILFNNTTLCPFKWRGKYLCFYCGEDMPNYEELKKHTKGHGPCTDRDRAIRLVKAADAEVKIDVSDITCEICKECFVSFDEIVGHLKHKHELPYDTGVKLSLVIYRLIDLQCLFCEEKFNYFNKLIKHVNNMHPSESFECCKCLQMFNKKRDLDAHTRMHHKKDYRCLKCSVTFASYAVFKKHNLNSHISTCNVCFKNFASLKKRLKHMKQEHANDMLQCGFCSKTMSTKQSFLRHATKCNLRINSSEKVIVDDEDRKPSVIQIRNNVACVLNMSTAIPFKYFMSRFRCFYCPKDFYECTDLREHTVTEHPHCDIKLKSMKLRNRHDGCIKIDISSLSCKLCFEPIHDLEALIDHLIFNHKANYDKSIDCNMQPYRLIKDNFSCPLCGEVYRYFSSLLRHIGNFHTDNKYICVYCGKSLRNVSNLRAHVSSKHNTAVHKCSKCDMEFNSNSHLQTHLGSAHGMKVIQCSECQEKFISNYRMQRHMVNVHRSGHKCTFCGKLFTRNSLMKNFFADEIAHSKYENYTSERRRKNLKILFNNTSIIPFKWRGKYLCFYCGKNYADYPEFKKHTKSHGLCTTKDYSLKLVKGSHNEIKIDISDMNCEICNEPFTSLDEIISHLIGKHSLEYDKSIVIAYQEYLLADSLCQFCGEHFEYFGYLITHINTIHPQNCFMCDDCGLTFNKKRDLAYHIRQNHRRGGYPCDECSDVFESQGLMRKHKNTFHFRKCKSCHSRFASFTLLQKHIKLEHSVTAIKKCPHCAKECHSRQGLMQHLRTCKVKMIVKRDKPTTFPSRMLLMPRKTQNISQIRQNIVCVLNMSTVIPFKFFAKFSCFHCSKKFTEFEELKEHTALEHPVCDMKSKCIIKCKGERTCVKIDVTSLACKICCQSMEDLDALIDHLISKHKANYDKSLTECFEPFKLVKDNIPCPHCSNMFRYFATLIRHINAEHCNSKRICDFCGRCFKNAANLNVHIIYTHTGSCECDICGLKFKNQWCLGRHKAKSHDAKDFKCPKCPEQFQSQYHKQKHLIQVHDIGHKCSYCGRMFTRNSFMKDHIRRTHLKEKNVPCSVCNEKFFDNYLLKLHMVKHDGERKFSCSVCSKTFLRRSNLSSHMDMHKKYGHVQGAKYNSVEDKYKKRELARKLLLKRRNVEYVLQYGNVTPFMWYKGRYRCFYCAEPMKDPVLLREHTAKVHQFANLELVVHDRTKNNRNRDAAVKIDVTDISCKLCPQAVNSLEQLIHHLIIAHDAEYDVSVPNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKHHLAHDYICDVCGTSFQGENHLKMHNRYYHREGGYTCEHCGLSLATLSKKTLHEKNVHMINLSTCPHCPETFKSPYFKKLHLANVHGVEELKIKCPYCPKVYPQESIMSRHMRRVHLREKNVECEVCGDKFFGPYDVKLHMLKHNGDKKFVCTVCGKKFSKKSNLNSHFVIHTGSKKYSCKICNKDFAHRPNLRIHFRTRHPDYETRFVVEESTGIIDEVDDSEIVQMDFVRDELEGAELTGQYID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -