Murs022193.1
Basic Information
- Insect
- Megathymus ursus
- Gene Symbol
- Zfa
- Assembly
- GCA_003671415.1
- Location
- PDGT01000067.1:1526561-1532660[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0012 0.094 13.6 0.3 1 23 309 331 309 331 0.98 2 10 7.6 5.8e+02 1.6 8.5 1 23 335 357 335 357 0.96 3 10 0.17 13 6.8 2.1 2 23 362 384 361 384 0.92 4 10 9.6e-05 0.0073 17.0 8.3 1 23 387 409 387 409 0.97 5 10 0.0013 0.1 13.5 0.4 3 23 415 436 414 436 0.93 6 10 0.014 1.1 10.2 0.4 3 22 446 465 445 469 0.92 7 10 0.0006 0.046 14.5 0.9 2 23 483 505 482 505 0.95 8 10 9 6.8e+02 1.4 8.5 1 23 511 533 511 534 0.93 9 10 2.6e-05 0.002 18.8 0.2 2 23 544 565 543 565 0.97 10 10 0.00019 0.015 16.1 2.0 1 23 571 594 571 594 0.97
Sequence Information
- Coding Sequence
- ATGTACGAGGAAGAAGAAATAGAATGTTACGGTTCGCAGCCATCAAATAGTATTTGTTATGCGTGTTTATGCAGAAGTCGAAAAACAGTGCCTCTGGGGGAATACTCTGCAATTTTtaacagaataatatttaatgttgaaCGTCAACCACCAAGATGTTTATCTACATTAGCAATGACACCAGTGAAAATAGATGTACACTATGGTGATGAATTGAATGAAACACGTCatggatttaaatttgaagtgaaACCATTTGTATATCAAAGAAATTTTAACACTAGCAATgtgttatatgaaaattatatccATAGCAATAAGAATGAAGATGATTGCTGTACGAAATTTGAACAAACCGCCTCATCAGAAGATTGTATGGACAATCAATCAgacaataattatgaatatttgaataagaataaaaatagcaattattatttaaaatgtaacagcAAAAAGGAACCTAATTTTAACAATACTGAAGTCAATAGAAGTGATATTGTAACTAAATCAGATAAAGAGGTGACAAATAATGAGGGATATGATAATGGaatgtttaataacaaatttaattcaagTAGCAATAGTATAGATTCAAAccaagaattaaaatattatttaaacagtaaatctagtcaatttaaattaaataaaaatgacaaacttGTAAGAAGAAAGGGTTTAAGGAAGAAAGATTTAGAAGAACATTTTAGAATAGTTGGTGCAATATCGAAGGAAATTAAAcgatttaaatcaaaatgtaaaatagATGCCAGTGAACTAGAGTCTTGCAGGGAAATGGAGAGATCGATTGATTTCTACGTTGACCAGCCTTATAAATGTCATAACTGTATTTGTGCATTTTCAACTCCCAAAAAGAAATATGAACATGACAAGAAATATCATGATAATACATCCGGTGTTTACATGTGCGACATTTGCACCAGCACGTTCGCCAGCAAGCGGCAGATGGCAGCACACGTCTCGAAACATTACTACTTGCACCGGTGCCACCTGTGTCAGTTCCAATGCTTCTCGAGGCAGGCGATGAAGTCGCACATGGGCCGGCACAAGCGGCTAGTAATGTGCGCGCATTGCGATGCGTGTTACTCTAACGTCGGTCTGTTCTATAAACATTTCAAAGCAAACCATTCAGTGTTTATCTGCGATCACTGTGGTAAAAGATGTCGAACGAAATACACTCTTGAGAAGCATGTGAGGCACCACTCCGAAAAGAACATATGTCTCATATGCAACAAGGTGTACGCGTCGCGCAACTCACTAAGGAACCACAGTGAGATGAAGCACAAGGAGACCTCCAGCGAGATGGCGTACTGCGTCAAGTGCGACAAGCAGTTCCCCAACGTGCCGCTGTATAAGCGCCACGTGCAGACCAGCAAAGCGCACGCGGCTGAACGAGACGCCGATAGaagTAAGAAGCAAGTGAGCTGCCCCATATGTGGGAACATTTACTCGAGGAAGACATACATGATGAACCATTATCGCCACGTGCACATGAAGCAGTCCAAACATTATTGTACTGATTGTGACAGGCATTTCCTCAACCGGACCAGGTACGTCGAGCATCGGAAGTACCACCACGAGGGCGAAACCAAAGCGAAGAACAAGATGTGTAACATTTGTGGACGGGGGTTCGCTGCAAACAGAACATTGGTGAATCACATTCGTACGCATTCTGGGGAGCGGCCGTACGAATGTCAGTATTGCGACGCGAAATTCACTCAGAAGCACGGAATGCTGTCCCatatcaaatatattcatatgaaGAGCAAACGACGAGGGTTTCAGTGA
- Protein Sequence
- MYEEEEIECYGSQPSNSICYACLCRSRKTVPLGEYSAIFNRIIFNVERQPPRCLSTLAMTPVKIDVHYGDELNETRHGFKFEVKPFVYQRNFNTSNVLYENYIHSNKNEDDCCTKFEQTASSEDCMDNQSDNNYEYLNKNKNSNYYLKCNSKKEPNFNNTEVNRSDIVTKSDKEVTNNEGYDNGMFNNKFNSSSNSIDSNQELKYYLNSKSSQFKLNKNDKLVRRKGLRKKDLEEHFRIVGAISKEIKRFKSKCKIDASELESCREMERSIDFYVDQPYKCHNCICAFSTPKKKYEHDKKYHDNTSGVYMCDICTSTFASKRQMAAHVSKHYYLHRCHLCQFQCFSRQAMKSHMGRHKRLVMCAHCDACYSNVGLFYKHFKANHSVFICDHCGKRCRTKYTLEKHVRHHSEKNICLICNKVYASRNSLRNHSEMKHKETSSEMAYCVKCDKQFPNVPLYKRHVQTSKAHAAERDADRSKKQVSCPICGNIYSRKTYMMNHYRHVHMKQSKHYCTDCDRHFLNRTRYVEHRKYHHEGETKAKNKMCNICGRGFAANRTLVNHIRTHSGERPYECQYCDAKFTQKHGMLSHIKYIHMKSKRRGFQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -