Basic Information

Insect: Megathymus ursus
Gene Symbol: znf574
Assembly: GCA_003671415.1
Location: PDGT01000118.1:488371-491078[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.11 8.3 7.4 0.0 3 23 39 59 38 59 0.97

2 8 0.089 6.8 7.7 2.5 2 23 169 191 168 191 0.93

3 8 2.5e-05 0.0019 18.9 2.4 1 23 204 227 204 227 0.97

4 8 2.5e-05 0.0019 18.9 6.0 2 23 268 289 267 289 0.97

5 8 0.00074 0.057 14.2 5.0 1 23 295 317 295 317 0.97

6 8 4.9e-05 0.0037 18.0 4.6 1 23 323 345 323 345 0.98

7 8 1.1e-05 0.00082 20.0 3.4 1 23 351 373 351 373 0.98

8 8 0.059 4.5 8.3 4.3 1 20 379 398 379 400 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.11	8.3	7.4	0.0	3	23	39	59	38	59	0.97
2	8	0.089	6.8	7.7	2.5	2	23	169	191	168	191	0.93
3	8	2.5e-05	0.0019	18.9	2.4	1	23	204	227	204	227	0.97
4	8	2.5e-05	0.0019	18.9	6.0	2	23	268	289	267	289	0.97
5	8	0.00074	0.057	14.2	5.0	1	23	295	317	295	317	0.97
6	8	4.9e-05	0.0037	18.0	4.6	1	23	323	345	323	345	0.98
7	8	1.1e-05	0.00082	20.0	3.4	1	23	351	373	351	373	0.98
8	8	0.059	4.5	8.3	4.3	1	20	379	398	379	400	0.93

Sequence Information

Coding Sequence: atgaGTGCTGACGCAGCTTCCTTACCGTGTCCAATATGTTTACATACTGGAGTATTTGACTCAGTACAATCTTTGAAAGatagattaatatttgtttcgaCTAATGTAATACTGTGCCCTGTATGTCAAGAAGAAGTATCCGGGCTAGATAAACTTACAATACATTTGTTTAGCCATGTGaaagtattaacaaaaaaaagtgttacTGAAAAACATGAAAACAGTGATAAAATATCCCAATCGAAATCTGAAAATGCTTGCGTATTAGAGCAACAGCAAAACAAGCTGAGAACGTcggtaactaaaaataaaactctaacATCCACGCCTGTTAATGCGCccgtaaaatatgtaaagattTACCCAAAGCTGCCAGTAATAGCTCTGAATACAATGCCTGTGATTGATATAACACGTGCTTCTATAGATGGTTgtataaataaaggaaattcATCGTATATACCACCGGCTAAAAATGAAACAACAAATGgacaagttaataataaatgtaatatttgtggtCTGCAATTTGTGGATTGTGATATTTTAAGAATGCATAGATGCCTTATTCATAACCTTGATGATAAAGTTGAGCAAAGTGTTACGCGGTATAACTGCCACCTTTGtccaaaacatttcaaaatgagAGGATCACTCATGGTTCATTTAAGAGTAGCTCATTTCGGATTTCCctcaaataatgtaacaaataatccggaaaatactaattttaaaggTAACTATTCAAATGAACTCGAGGTAACATCAAATAATCTTGAAAGAAATGATGGCAAGCAATGGCAATGTGAAGATTGTCGGAAATGTTTtactactaaatattttctgaaGAAACACAAGCGTCTACATACAGGTGAAACTCCATACGCGTGCACTctgtgtaataaaacatttacatttcaacAATCTTATCACAAACATCTTTTGTATCATAATGATGAAAAgccacacacatgcacattttgTGGCAGAGCTTTTAAAGAATTGTCAACATTACATAACCACCAACGTATACATACCGGCGAGAAACCGTTTTCGTGTGAAACCtgtggaaaATGTTTTAGACAGAGGGTTTCATACCTAGTTCATCGTCGCATACATACTGGGGCTATGCCGTACAGGTGTACTGCTTGTAACAAAAGTTTTAGATACAAGGTTTCACAAAGGACTCATAAATGTCAAGCTCAGCCACCGGGTACTGTAATACGAAAAACTGGTGACCTTGTGGAAAAACTTAAAAGGAAACATACCGATACTGGAAAGATAAACATAGAAAATGAAATGACTGTTGTCCAAGACGTAACATATGCAGAAGTTTCTGAAGCTAACGCTGAGCTAGTTCGCACTGGAGCTAAAATATCATTAGAAGATATGGAATCTGATAATTTCAACATAATTGCCGACAgctttaatgttaataacgaTCACGGCCGACCAGACACTAGTTATTCTACTCGAATCATAGTTAGTGATGtcgctgaaataaaaaataatatcgttgAATCGAACATAGAAGAACTTATAGAGTCTTTACCAGCCGTAGACAAAAACGTACCTTCGCCAtcggatattttaaaaaatttgtgcTTGTCTACCGATGAAGAATTAAGTAGTGTTTTAAAAGAGCTGATATga
Protein Sequence: MSADAASLPCPICLHTGVFDSVQSLKDRLIFVSTNVILCPVCQEEVSGLDKLTIHLFSHVKVLTKKSVTEKHENSDKISQSKSENACVLEQQQNKLRTSVTKNKTLTSTPVNAPVKYVKIYPKLPVIALNTMPVIDITRASIDGCINKGNSSYIPPAKNETTNGQVNNKCNICGLQFVDCDILRMHRCLIHNLDDKVEQSVTRYNCHLCPKHFKMRGSLMVHLRVAHFGFPSNNVTNNPENTNFKGNYSNELEVTSNNLERNDGKQWQCEDCRKCFTTKYFLKKHKRLHTGETPYACTLCNKTFTFQQSYHKHLLYHNDEKPHTCTFCGRAFKELSTLHNHQRIHTGEKPFSCETCGKCFRQRVSYLVHRRIHTGAMPYRCTACNKSFRYKVSQRTHKCQAQPPGTVIRKTGDLVEKLKRKHTDTGKINIENEMTVVQDVTYAEVSEANAELVRTGAKISLEDMESDNFNIIADSFNVNNDHGRPDTSYSTRIIVSDVAEIKNNIVESNIEELIESLPAVDKNVPSPSDILKNLCLSTDEELSSVLKELI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01439390;
90% Identity: iTF_00971695;
80% Identity: iTF_00971695;