Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:530942-542833[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.026 2 9.4 0.5 1 20 215 234 215 236 0.94

2 10 0.34 26 5.9 0.5 2 22 264 284 263 286 0.88

3 10 0.79 61 4.7 3.3 1 23 309 331 309 331 0.97

4 10 0.00079 0.061 14.2 0.5 1 23 335 357 335 357 0.98

5 10 0.0013 0.099 13.5 0.6 1 23 362 385 362 385 0.94

6 10 0.015 1.2 10.1 0.4 2 23 393 415 392 415 0.93

7 10 0.00027 0.02 15.6 6.1 1 23 422 444 422 445 0.95

8 10 0.0012 0.094 13.5 0.9 1 23 451 473 451 473 0.96

9 10 1.3e-07 9.8e-06 26.1 3.3 2 23 480 501 479 501 0.96

10 10 9.4e-06 0.00072 20.2 4.3 1 23 507 529 507 529 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.026	2	9.4	0.5	1	20	215	234	215	236	0.94
2	10	0.34	26	5.9	0.5	2	22	264	284	263	286	0.88
3	10	0.79	61	4.7	3.3	1	23	309	331	309	331	0.97
4	10	0.00079	0.061	14.2	0.5	1	23	335	357	335	357	0.98
5	10	0.0013	0.099	13.5	0.6	1	23	362	385	362	385	0.94
6	10	0.015	1.2	10.1	0.4	2	23	393	415	392	415	0.93
7	10	0.00027	0.02	15.6	6.1	1	23	422	444	422	445	0.95
8	10	0.0012	0.094	13.5	0.9	1	23	451	473	451	473	0.96
9	10	1.3e-07	9.8e-06	26.1	3.3	2	23	480	501	479	501	0.96
10	10	9.4e-06	0.00072	20.2	4.3	1	23	507	529	507	529	0.98

Sequence Information

Coding Sequence: atggaACACACATTGAACCATGGAATGTGTCGGTGTTGTGCGTCAGAgggattatttaagaattttaactCGACATATCAATGGATGGGCGCCGACGAAGTTTATGCAGACATGTTGAAAGAATGTTTCGATATTACGCTCACAACTGCAGAGGAATGGAATAATGGAGGAATCTGTGAGGTGTGCATTACGCAGCTTCGAAATGCTTCCAACTTCAAGAAGCAGGTCCTACAAACTGAGGACCAGTTTAAAAAAGCACTACACGATAAATTGTTTCAAGCAAGCATAGTCAAAGAAGAGCTGAATAGAGAAGATGGAGACTTGGAAGTTGGAGACTCTGACCACAATGTCTCTGAAGATTATTCTGGAACAGACTTCGATGTGTCCATCAAAGAAGAGATGGAAGAGCCAAAATCAAAAAAGAGGGCAGCTAAAGCTGGTACATCGAGGGCTAAGAAGGCGAAAACAGAAGATGGCGAGCCATCAGCTAAACGAACGGACGGCGACTCGCCCAAGtgcaagaaaaagaaaaagagatCGGACGTAAGCGCAACACCCGAGCGAATTGAGCACAGGGTCAACTTGACCGCGATACTACAGTATTCTAATGCCAGCCCGTTCAGGGATAAGACTATCAAAGGTTTCTCTTGCCTCTATTGCGCTAAGCACTTCCAAGATATCGATGATCTCCGCTCGCATACGGCTCAGAAGTCCGAAAAGGCCAAAATCAACAAGATGCTCGACTATAAACTCAGCTATAACCCCATTAAGGTCGATATCACTGACCTACGTTGCAccgtttgtaataaaaacatgcaCGATCTCAACGACCTTAAAGATCACCTCGTCGCCGAGCACAATAAAGTCATTCATAAAGATATCAAGGATATCATATTACCGTTTCGGCTAGAGGATGGCAAAAACTTCACTTGCGTTATCTGTTCCGTCGTTCACGTATCGTTTAAGAATCTCTACCACCACATGAGTAGTCACTACCGTAATTACTGTTGTGATAAATGTGGAGTTGGCTACATAACGATTGGAGCTTTGAGGAAACACGGAAAGACACATTATCAAGGCAACTTTCCATGTGAGTACTGCGACAAAGCCTATACATCGCTCACGAAGAAGCGCAATCACGTAAAAGGTGTCCATACTGGCGGCTGGCTTAGGAACAAATGTCCACATTGCCCAGAGATTTTCGTCAGTTACTACGACCGAAGTGAACATTTGGTGAAAGCTCACAACGAAGTGCCGATAATCTATCCATGCAACGCGTGCAATAAGACATACAAGAAGAAGTTTGAATTGAACAGGCATATAAAGCACCATCACCTCCAGCAGAGAAATTACCTATGCGATAAATGCAACGCCAATTTCTTCTCCAAACGCGGTTTAATAGACCACATGTCGAAGCATTCGGGCGTCGAAATGTGCTCTTGTAACGTGTGCGGCAAGTCATTCTCTCGGTCGAGGACGCTCAAAGAACACATGAGAATTCACGATGACGACAAAAAATATCAGTGCGAAGTGTGCAACAAGACGTTCATGCAAAAATGCAGCTTGAAAAGCCACTTACGTCTGCATCAGGACGACCTAGATATCTTCAAGGAGTTTGATGACGTCAAGCATTTGATAGACAATAGGGAGGTTACGTTGAAACAGATCGCGGCCGAGAACAAAGCTAAAGAACTCGCCGAAAAGATCAAGCATCAAATTGGACACGattgttga
Protein Sequence: MEHTLNHGMCRCCASEGLFKNFNSTYQWMGADEVYADMLKECFDITLTTAEEWNNGGICEVCITQLRNASNFKKQVLQTEDQFKKALHDKLFQASIVKEELNREDGDLEVGDSDHNVSEDYSGTDFDVSIKEEMEEPKSKKRAAKAGTSRAKKAKTEDGEPSAKRTDGDSPKCKKKKKRSDVSATPERIEHRVNLTAILQYSNASPFRDKTIKGFSCLYCAKHFQDIDDLRSHTAQKSEKAKINKMLDYKLSYNPIKVDITDLRCTVCNKNMHDLNDLKDHLVAEHNKVIHKDIKDIILPFRLEDGKNFTCVICSVVHVSFKNLYHHMSSHYRNYCCDKCGVGYITIGALRKHGKTHYQGNFPCEYCDKAYTSLTKKRNHVKGVHTGGWLRNKCPHCPEIFVSYYDRSEHLVKAHNEVPIIYPCNACNKTYKKKFELNRHIKHHHLQQRNYLCDKCNANFFSKRGLIDHMSKHSGVEMCSCNVCGKSFSRSRTLKEHMRIHDDDKKYQCEVCNKTFMQKCSLKSHLRLHQDDLDIFKEFDDVKHLIDNREVTLKQIAAENKAKELAEKIKHQIGHDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00673811;
90% Identity: iTF_01439329;
80% Identity: iTF_00971658;