Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000006.1:5797244-5805374[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.03 2.3 9.2 0.2 3 22 250 269 249 269 0.94

2 10 1.7e-05 0.0013 19.4 0.4 1 23 301 323 301 323 0.98

3 10 0.0014 0.1 13.4 0.1 1 23 329 351 329 351 0.92

4 10 0.0018 0.14 13.0 0.3 1 23 356 379 356 379 0.98

5 10 0.0025 0.19 12.6 4.2 1 23 385 407 385 407 0.98

6 10 1.5e-05 0.0011 19.6 0.1 1 23 413 436 413 436 0.94

7 10 0.051 3.9 8.5 1.7 1 23 445 468 445 468 0.97

8 10 0.026 2 9.4 0.7 3 23 476 496 474 496 0.97

9 10 0.011 0.82 10.6 5.5 1 23 502 524 502 524 0.98

10 10 2.9e-05 0.0022 18.7 4.5 2 23 530 552 529 552 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.03	2.3	9.2	0.2	3	22	250	269	249	269	0.94
2	10	1.7e-05	0.0013	19.4	0.4	1	23	301	323	301	323	0.98
3	10	0.0014	0.1	13.4	0.1	1	23	329	351	329	351	0.92
4	10	0.0018	0.14	13.0	0.3	1	23	356	379	356	379	0.98
5	10	0.0025	0.19	12.6	4.2	1	23	385	407	385	407	0.98
6	10	1.5e-05	0.0011	19.6	0.1	1	23	413	436	413	436	0.94
7	10	0.051	3.9	8.5	1.7	1	23	445	468	445	468	0.97
8	10	0.026	2	9.4	0.7	3	23	476	496	474	496	0.97
9	10	0.011	0.82	10.6	5.5	1	23	502	524	502	524	0.98
10	10	2.9e-05	0.0022	18.7	4.5	2	23	530	552	529	552	0.95

Sequence Information

Coding Sequence: ATGGACGGAAGGTGTCGGTTGGATTGTAGCAACTCTAGTAGAGTTTGTATGTATTCAgaactaacaaataaaatttgtcaagtATGTGTTGATCAACTAGAAAATGTGTATAAgtatcgtaaaaaaattataagaaataacctaatactacttaaaaatattagagaAAATATTACCTACCATCCAACAATGTTATATTCTGAAGATTCACAGAAAGAAGTTGATATTAATGAAGTAAATGATGACATTGTAAGATTCAATGGAGATGATGAATCTGATACAAAATTGACTGTTAATGAAGAAATAggtactgaaattaaaaaactaaaagatGCTTCTGAACAAAAAGAAACAGAACACAACATAGGATTGAATAACATTAAGACCAATGAACTTCACATCAGagtaaatgaattaaatgacTTACACAGAAATCAGCAagatgtgaaattaaataattcagatGTAACCAAAAAAGAAgacattaatgatttaaatgaaaataaaaatagcttagataaaaacaaaaaacctttACCATCTATTCCTCCAATCATATTTCAATCTATTAATCAGTATAATTCTACATTAGAAACAGATAAAGAAAATGcagatataaacaatttaactaCTACTGATTTTACTGTCAATgacaatgaatttatatttaaaaatctagaTGGAAATCCtggtgttattttaaatcaagAACATGTTAATACATTgaatatagacaaaaaaaatatgtgcctTATGTGTCTAAAGATTTTTGAATCTCAAAAAGAATTATCTATTCATTACAAGACTGTGGAACTCTCTAAAGCTCCGAAGGAGACATCAAAGAAATGTATGGAAGTAAACATGTTAAAGGTTTTAAAGAATTACGATGATAAGACTGTGTTTCAGTGTAGTGTTTGCAGTAAAGTTTTCGAGAATAAAGCTTCGGTTATAAAGCACACACAGGTACATAAAATTGAACGGCCATTCGTATGTAATTTGTGCGGCCGAACCTACAAGACTGTAGATGATATTCTAAGGCATGGTGTGGTGCATAGTGGCAACAAATTTGTATGTTCATATGAGTGTGGGTATGCCACTGTCCATCTGGGTGCATTGCGAGATCATGTCAAAAGGCATAAGAAGGAATTCAAGTACAAATGTGAAAAATGCAGTAAGTGTTTTCAAGTGAAGACCTGGTATGACCAGCATCAGAATGTCCACAACAAGATCCGACCCTTTGTGTGCAATATATGTGGGCAATCATTTAGCATGGCAAGgtACCTAACCGCCCACCGTGCCAATGTTCACCCTCAGTCGTCGAAGGTGAAACGTTACAAGTGTGTGCAATGCGCCCTCCCATGCGACTCTCGGAAGAGCCTCGTGATGCATATGAAGCAAAAACACGGAATGAAGACCGACTGCCTGTGTGACGTATGTGGTCAGATCCTGCCCGACCAGCAGAAGTTGAGCCTTCATAAAAACACCCATAAGACAACAAGAAAGTACAGCTGTATGTTCTGTAAAAAGACGTTCAATAAAAAGGATCATAAGACAGTCCATGAGAAAATACACACCGGGGAGCGACTGAACTGCAACAGCTGTCCCAAGTCGTTCACACAGCGCTGCAGCCTTCGAAGACATATTAAAAGATATCATCCAGGGGATCAGCTATCAGTAGAGCAGAAaatctag
Protein Sequence: MDGRCRLDCSNSSRVCMYSELTNKICQVCVDQLENVYKYRKKIIRNNLILLKNIRENITYHPTMLYSEDSQKEVDINEVNDDIVRFNGDDESDTKLTVNEEIGTEIKKLKDASEQKETEHNIGLNNIKTNELHIRVNELNDLHRNQQDVKLNNSDVTKKEDINDLNENKNSLDKNKKPLPSIPPIIFQSINQYNSTLETDKENADINNLTTTDFTVNDNEFIFKNLDGNPGVILNQEHVNTLNIDKKNMCLMCLKIFESQKELSIHYKTVELSKAPKETSKKCMEVNMLKVLKNYDDKTVFQCSVCSKVFENKASVIKHTQVHKIERPFVCNLCGRTYKTVDDILRHGVVHSGNKFVCSYECGYATVHLGALRDHVKRHKKEFKYKCEKCSKCFQVKTWYDQHQNVHNKIRPFVCNICGQSFSMARYLTAHRANVHPQSSKVKRYKCVQCALPCDSRKSLVMHMKQKHGMKTDCLCDVCGQILPDQQKLSLHKNTHKTTRKYSCMFCKKTFNKKDHKTVHEKIHTGERLNCNSCPKSFTQRCSLRRHIKRYHPGDQLSVEQKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00971615;
90% Identity: iTF_00971615;
80% Identity: iTF_00971615;