Murs015887.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megathymus ursus
Gene Symbol
-
Assembly
GCA_003671415.1
Location
PDGT01000094.1:939202-943476[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00017 0.013 16.3 2.3 1 23 56 79 56 79 0.95
2 10 2.5e-05 0.0019 18.9 2.5 3 23 88 109 86 109 0.94
3 10 0.19 15 6.6 5.3 2 23 117 139 116 139 0.95
4 10 1.4e-05 0.0011 19.6 0.4 2 23 147 169 146 169 0.92
5 10 0.0091 0.7 10.8 8.2 1 23 176 199 176 199 0.93
6 10 0.0017 0.13 13.1 6.4 1 23 205 228 205 228 0.95
7 10 4.9e-05 0.0037 18.0 0.3 2 23 236 257 235 257 0.97
8 10 0.0017 0.13 13.1 1.9 2 23 265 287 264 287 0.96
9 10 0.00013 0.0097 16.7 3.5 2 23 294 316 293 316 0.94
10 10 8.5e-05 0.0065 17.2 4.2 1 23 326 348 326 348 0.97

Sequence Information

Coding Sequence
ATGGAGGAACCGCCGAAAGCTCCACTGGAGCCGAAGCCAGAGGAATCCAAGCCGACCAAGTTCATCAGCGTCAACAATCCATCGCTGACGGAGGAGCAGCGGGCGATGTACGAATCGGTGCTTACCACTTGGAAGCCGGTGCTTTTTCCAAAACGCATCAAACGATACATCTGCCAGAAGTGCAACAAGGAGTTCAAGAACTACCAGAACTTGTATCTGCACACCACGCGGGTGCATTCCTCCGAGGAGTCGGCCGTCATTTGTGACATATGCGACAAGACGTTCAAGAATAAACATTATCTTTACATGCATCGTATGAATAAACACTATTCAGAGTCGGAGAAATGTTACTGCCAGTTCTGTCTCCAAGAGTTCAGGACGCGGCGGGCGCTGCACATGCACGTGAAGCGAATCCACCCGAACACCCTGCCCGAGATCAAGTGTCCAGAGTGCGGCAAGGAGTTCAGCGTGCCCTACAAGCTGCGGTACCACATCGACGCCTGCCACCGGGTCGAGACCGAGAAATACAAATGCCACATATGTCAAAAGCTGTACAAGAGCCACCTCAACCTGAATCGTCACCTCCACTTCCAGCATACCCAAGTGGAACGTCACACCTGTGTCTTCTGTCCGATGACGTTCAAGTCGCGGCATCATATGAAACGTCACATCCTGAACATCCACCCTCCCTTGGAGTCCAAAGTCACCTGTCCGGAGTGTCTCAAGGAGTTCAAGAACGATCAGTATTTGAAGGAGCATATGCAGGTGCACTCGTCGTTCGAGACGAAAGTGAAGTGCGAGCTGTGCGACAAGTACTTCCACTCGGCGGTGAGATTGAAGAAGCACAAGAAGATAGTCCACCCGGACAAGCCGAAGATCCGGTGCGAGAAGTGCAACAAGGAGTTCGCTCACGCCCACTACCTGAGGCGGCACAACAACTCGGTGCACATCGACATGGACGAGAGCCAGTACCAGCACAGCTGCGAGCAGTGCGGGAAGAAGTTCAAGATCAGGAGGTACCTAAACAACCATCTCCAGAGACACGAGCAGCAGCATCTCAAACGGATCTCCCAGATGGTGAAGACGGTGATGGGAGCCGACGGTGAACCGGTGGAGAAGCAGCCGAAGAAGAGGGGCAGGCCGCGGAAGAGCACCAGGAAGGAGATCGAGTTCATTAAATGCGAACCGGTCTCCAGCAGCGGCTCGGACGCCGACTCCGATGAAGAGACCGACTCGGAGTAG
Protein Sequence
MEEPPKAPLEPKPEESKPTKFISVNNPSLTEEQRAMYESVLTTWKPVLFPKRIKRYICQKCNKEFKNYQNLYLHTTRVHSSEESAVICDICDKTFKNKHYLYMHRMNKHYSESEKCYCQFCLQEFRTRRALHMHVKRIHPNTLPEIKCPECGKEFSVPYKLRYHIDACHRVETEKYKCHICQKLYKSHLNLNRHLHFQHTQVERHTCVFCPMTFKSRHHMKRHILNIHPPLESKVTCPECLKEFKNDQYLKEHMQVHSSFETKVKCELCDKYFHSAVRLKKHKKIVHPDKPKIRCEKCNKEFAHAHYLRRHNNSVHIDMDESQYQHSCEQCGKKFKIRRYLNNHLQRHEQQHLKRISQMVKTVMGADGEPVEKQPKKRGRPRKSTRKEIEFIKCEPVSSSGSDADSDEETDSE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00943106;
90% Identity
iTF_00167147;
80% Identity
iTF_00971597;