Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000034.1:555037-561492[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0021 0.16 12.8 1.8 3 23 409 429 407 429 0.92

2 8 1.4e-05 0.001 19.7 3.9 1 23 435 457 435 457 0.98

3 8 2.9e-06 0.00022 21.8 1.9 2 23 466 487 466 487 0.97

4 8 1.9e-05 0.0015 19.3 0.6 1 23 493 515 493 515 0.99

5 8 6.8e-06 0.00052 20.7 1.2 1 23 521 543 521 543 0.97

6 8 2.7e-06 0.0002 21.9 1.6 1 23 549 571 549 571 0.97

7 8 0.00069 0.053 14.3 7.4 1 23 577 599 577 599 0.97

8 8 5e-05 0.0038 17.9 0.9 1 22 605 626 605 626 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0021	0.16	12.8	1.8	3	23	409	429	407	429	0.92
2	8	1.4e-05	0.001	19.7	3.9	1	23	435	457	435	457	0.98
3	8	2.9e-06	0.00022	21.8	1.9	2	23	466	487	466	487	0.97
4	8	1.9e-05	0.0015	19.3	0.6	1	23	493	515	493	515	0.99
5	8	6.8e-06	0.00052	20.7	1.2	1	23	521	543	521	543	0.97
6	8	2.7e-06	0.0002	21.9	1.6	1	23	549	571	549	571	0.97
7	8	0.00069	0.053	14.3	7.4	1	23	577	599	577	599	0.97
8	8	5e-05	0.0038	17.9	0.9	1	22	605	626	605	626	0.95

Sequence Information

Coding Sequence: ATGTGTGAATGGTTGGCATGCGGCGATTGGTGGGATGTGCGATTAATCTGTGGGGATCGTTCCTTTAACGCTCATCGCGCAGTTTTGGCTAGTGTCAGCACTTTTCTCAAGAAATTGCTTCTTTCTTGTCCAGTGGATGAATCACCAGTTAATATATTCTTACCAGAATTCGATATCGACGCGATGTCATctgtactttattatatttacaacggCAAAGTGTTAATTCCAAAtcataagttaaaaatgttcataGATACAGCTAATGCGATGGAAATATTTATCGATACACGGTACATACCCGAAACAAACgagtgtaaacaaaatttttttgaacCTAATAgatgtgataaaatatttgcgaaaggaaattataatatttgtcaactaaaattatatcatgAAGAAgacgaattttttattaatgtcaaaaaaaGCATGGGAAGCGAAGAACAGGTACGCCAGCAACATACAGTTGGTAGTTTAAATCTGCAAGATAAATTTAATCACACATTCAGTTGGAGTAAAGAATATATCTCACAATTGGGTAATCTAACATCTATATCTGGAAACCGACAAAAGCAGTTATTCCTACGTGAAGGCAACATTAACGGTCAAACGTCAGGCGTGCTAGCAATATCAAATGAGGAGCATCCTATAGCGACATCTGCTTACTTCAGTAATGCTACGGAAAATTATGCCAATGTCTGCGAAGCATTCTCAGTTACATCTAATAGAACTTTAGCACAAAACAATCCAAAAACttcattttttagttattttaaacaaatacgtGATAATTATTACAGAGAAAggaataaagataatataaacatatcttATACTGCGTCTAATCATTTGGACGACAATTTTAACGTCaaacttttattacaaaaagaacaaaacattaatttctttaaaaattggTCAATTAATTCATCTTCAGACTTTCATGTAGAAACACAAAGTTCCTTTGGTCTTAAGTATGAGGGACTAAATTCCTTCTTTGAGACTCCAAAAGTTACTATTTTGAATGGGGTTCTACAGAACCCTTGGAATTCTCGGCAACCGAAGAGTTACGTACCGTTTCCTAAGAAAGCCCTTAATTCTAAGCATTTGGAAAGAAACCAGGAAAGCAaggcatgtGGTAGGCACGACGAGCAAATTAAAATCAGTGCAAATGTTTTTGGAGAACGAACAGTGTCCGAACAAAAAGATTTAAGTTGCATTGTGTGTCATGAGGTTTTTACAAGAAGGCAAGAGTACAGTAGTCATATGAGACAACATACCTCAATTACACGATATAGCTGCGGGGAATGTCATAAGACATTTTCGCAACTTCGCAATTATAAATACCACATGTCAGTCCATCGCGGCACCAAGGAGTTCGCAGCGAGTTGTACTGTATGcggaaaacattttaatgataaaggCTATCTCAGCAATCACATGAAAATTCATAGAAATCGAAAGGAATACAAATGTGCTTCTTGCCCCAAATCTTTCAATCAACGCGTCGCATTCAATATGCATTTACGGATTCATACAGGTGTGAAGCCACACGTATGTGAGGAGTGTGGAAAGGCGTTTTCTCGCAAGATGATATTGAAACAGCATCAACGCATACATTCGGGTGATCGGCCCTACGCTTGCGCGCACTGCGACAAGCGCTTTGCGGATAGATCTAACATGACTTTGCATCAACGACTCCATACCGgagtAAAGCCCTTTTCCTGTACATTGTGTGCAAAATCATTTACCAAGAAACATCATTTGAAGTCTCATTTGAATTTTCACACCGGGCTGAAACCTTACTCCTGTCCTCGGTGCAAACTCGCTTTTACCCAGTCGTCCAATATGAGGACTCACTTAAAAAAGTGTAatatgacaaattaa
Protein Sequence: MCEWLACGDWWDVRLICGDRSFNAHRAVLASVSTFLKKLLLSCPVDESPVNIFLPEFDIDAMSSVLYYIYNGKVLIPNHKLKMFIDTANAMEIFIDTRYIPETNECKQNFFEPNRCDKIFAKGNYNICQLKLYHEEDEFFINVKKSMGSEEQVRQQHTVGSLNLQDKFNHTFSWSKEYISQLGNLTSISGNRQKQLFLREGNINGQTSGVLAISNEEHPIATSAYFSNATENYANVCEAFSVTSNRTLAQNNPKTSFFSYFKQIRDNYYRERNKDNINISYTASNHLDDNFNVKLLLQKEQNINFFKNWSINSSSDFHVETQSSFGLKYEGLNSFFETPKVTILNGVLQNPWNSRQPKSYVPFPKKALNSKHLERNQESKACGRHDEQIKISANVFGERTVSEQKDLSCIVCHEVFTRRQEYSSHMRQHTSITRYSCGECHKTFSQLRNYKYHMSVHRGTKEFAASCTVCGKHFNDKGYLSNHMKIHRNRKEYKCASCPKSFNQRVAFNMHLRIHTGVKPHVCEECGKAFSRKMILKQHQRIHSGDRPYACAHCDKRFADRSNMTLHQRLHTGVKPFSCTLCAKSFTKKHHLKSHLNFHTGLKPYSCPRCKLAFTQSSNMRTHLKKCNMTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00970556;
90% Identity: iTF_00970556;
80% Identity: iTF_00970556;