Basic Information

Insect: Megathymus ursus
Gene Symbol: ZNF526
Assembly: GCA_003671415.1
Location: PDGT01000020.1:2107976-2134130[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 5.3 4e+02 2.1 2.0 2 19 490 507 489 511 0.89

2 18 0.005 0.38 11.6 0.0 1 23 521 544 521 544 0.95

3 18 0.38 29 5.7 2.1 1 21 664 684 664 685 0.91

4 18 0.0093 0.71 10.8 3.3 2 23 746 767 745 767 0.95

5 18 0.2 15 6.6 0.3 1 23 779 803 779 803 0.91

6 18 7e-05 0.0054 17.5 0.4 2 23 810 833 809 833 0.97

7 18 0.069 5.3 8.1 0.2 1 23 839 861 839 861 0.93

8 18 0.0021 0.16 12.8 3.3 1 23 867 889 867 889 0.98

9 18 0.7 53 4.9 0.0 2 19 900 917 899 920 0.89

10 18 0.0031 0.23 12.3 0.3 1 23 999 1021 999 1021 0.98

11 18 2 1.6e+02 3.4 7.2 1 23 1028 1050 1028 1050 0.95

12 18 0.0014 0.1 13.4 1.8 1 23 1091 1114 1091 1114 0.95

13 18 0.0017 0.13 13.2 0.7 1 23 1121 1144 1121 1144 0.97

14 18 0.022 1.7 9.6 0.1 2 23 1166 1188 1165 1188 0.95

15 18 0.00013 0.01 16.6 1.2 3 23 1212 1233 1210 1233 0.94

16 18 0.052 4 8.4 0.3 1 23 1248 1270 1248 1270 0.96

17 18 9.2e-05 0.007 17.1 0.1 1 23 1276 1298 1276 1298 0.98

18 18 0.00011 0.0085 16.8 1.4 2 23 1305 1327 1304 1327 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	5.3	4e+02	2.1	2.0	2	19	490	507	489	511	0.89
2	18	0.005	0.38	11.6	0.0	1	23	521	544	521	544	0.95
3	18	0.38	29	5.7	2.1	1	21	664	684	664	685	0.91
4	18	0.0093	0.71	10.8	3.3	2	23	746	767	745	767	0.95
5	18	0.2	15	6.6	0.3	1	23	779	803	779	803	0.91
6	18	7e-05	0.0054	17.5	0.4	2	23	810	833	809	833	0.97
7	18	0.069	5.3	8.1	0.2	1	23	839	861	839	861	0.93
8	18	0.0021	0.16	12.8	3.3	1	23	867	889	867	889	0.98
9	18	0.7	53	4.9	0.0	2	19	900	917	899	920	0.89
10	18	0.0031	0.23	12.3	0.3	1	23	999	1021	999	1021	0.98
11	18	2	1.6e+02	3.4	7.2	1	23	1028	1050	1028	1050	0.95
12	18	0.0014	0.1	13.4	1.8	1	23	1091	1114	1091	1114	0.95
13	18	0.0017	0.13	13.2	0.7	1	23	1121	1144	1121	1144	0.97
14	18	0.022	1.7	9.6	0.1	2	23	1166	1188	1165	1188	0.95
15	18	0.00013	0.01	16.6	1.2	3	23	1212	1233	1210	1233	0.94
16	18	0.052	4	8.4	0.3	1	23	1248	1270	1248	1270	0.96
17	18	9.2e-05	0.007	17.1	0.1	1	23	1276	1298	1276	1298	0.98
18	18	0.00011	0.0085	16.8	1.4	2	23	1305	1327	1304	1327	0.95

Sequence Information

Coding Sequence: ATGGATGAACCTCGGGCAGAACCACTGATCCTTTGTTTGGAGAATGCTGATAGAGAAGTTTCTGTTGAAATTGAATCGCATGACAACTTCCAGATGTTTTTGGACAAAGCCAAGGATTTACTTGGttatgaaatagatttaaattcaataactaATAACCAGCCGGTTTCGCTCACTGACaacatttatcaatttttattgaacGCAGAACAAAATCTAAGTAGAGATAACATAGAAATTGAGACATTTGACCTAATGGTTGAGCAAAATCCTAATGATGATCTAATTTACGTCTTGGATGACGGTACACAAATCAAAGCCTCACAAATACAGTTTGATAATGAGGATCCGCCTTTAGATTTGACAGCGGAGAAGATCCCTTTCATCAAATATGCTGATGATAGTGATGAAAATGAAGATGACAATGCCTTGGTAGaaaccacaaaaaaaattaacataattgaaaGCCCCGTGACCAAATGGTCGATTCAAAATTTAAGCCCGAAATGTAGTTTCGTTAATAGCCTCCCttttaaattggtctgtaatAACACTTCCAATTTTGAAGCTCAGTTTACTAAGTATTTAGAAACGAATAGCAAAAATTCCAATGTGAATGCCACTGTTAACAATGCTAACACTATCAAAAGCTACGATAAGAACTCCTCGAGACGAAACgatgattttaatttgacgAGAGAGGATATTCTTGATATGTTCAAAGACGCACCGGTGACATCCGCACCTTACCAGGAAAGAAGCTTTGCGGATAAACGGAAACATGCACGCAAAAGTGACCCTTCTAGAATGGCACATAAAACTTGGAATCCAAAACCGTTGTCTTGTGTCGTAGATAGTGATAGTCAAATGTGTTTCATCTGTAGAAAGTTTGTGGATAGTAGTCtagaaaaactatatttatttgacaatgaAGACCAAAAGCTACATAGATGTTCGCCCCAAAGGCGGTTTTCAACACAGCTCAAAATCTTGTGCGAGCAATGCTTGGCCGAAAACTTTAAGCCTTGTACCATTAAAAGTCCCACACAATCATTAAAACCcgatgaatatttaattattaaaaataatcaacaatacATCTTTCAAAAAGTAACTTCGATCAGTCTGAGGGATGCTGATAGCGATTATAAAATTCCCGAGGATTCAAACGATGATAAATTTGAACCTAATGCATTTATAGAAGTTTCTGATAAACAAGGAATGGATTTCGTTAAAGTGGAAATAGGCTCAGACGGAGAAATAGTTACAAAGGCGTTGTACGAAGATCCGGATTCATCGGATGATGTAATAATCGTGCAAAATAAAGAAAGAGACAGTTCTAGTGACGTTGAAATTGTAGAACCTGAAATAGATGATAACATTATTGAGAATTTAGATGACGCGGATGAAGATGTTAAGGAGTTTCTGGGGAAATATAATTGTGGTGTGAACGATGCGATAGAACTTAAATGCAGATTTTGCGAGAAGAACTTCGAAGATGTTACTGAAGTGACTAACCACTGTGAAGAACATAAGCATGACGTAGAAGATGGTGTTGTATTTCCGTGCCCTCTCTGTGATTATGGTTATGCAAATCTTAAATGGCTCAGAGGTCATTTAAAAGCGGCCCATGACAAGCCAAATGACACAGATACCAAAGAGGATGGGAAAGAAACTACCCCGTCTCCGATTCACTCGCCAGTGGCTAAAAGAACTCGCAGTGCAATTAAGAAGAGCGATGGTCCGAAAAGGACAGATAAACCAGAGAACATTATCAAGGACGAAGAAAATCCAAATAAGTTTGAGGAGAATGAGTCGAAAGAGCCCGAATTAGAGATCAAAATGGAAGTGAAACAGGAATCGTTAAACAGCAGTGATGATGAGATCTGGATACTGCAGACAGGTGATGACGATGCCACGGAGACATTGCAACAGCTGCTGCAAGGGGTGAAGGTTAAAAATGAAAACGGACCTGAAGTCACAAAAGTCCACAATTGTGCCAACTGCAGTCAGTCGTTTACGTCTACGACGTTGCTTCTCGAACACAAATGCGTCAGACGGCGAGGGCGAAAACGCAAGGCGAAGGGTGGCGTGTGTGTGCCGAAGAAAGAAGATTTCTTCAAGcgCGCTCAAGAACGACCTAGGCAACCATCAGTGGACATTGATAATGATTTATTGGTCGAGAGACCTCGTAAGAAGAGAAACCGCCAGCCCACATCAGATCCCCAGATAGTCACGTGCCACGACTGCAACGAGTCATTCACCTCTAAAGTTCGCCTCAAGTTTCACATGCAATTCCACGAGTCCAACTCCTTCCTAACGCCCGGTGGTGAGTATAAGTGTCCGGAGTGCGAGGACGCAGCGTTCCCGACTGAAAGCGAACTCTTCGACCACGTGCACTTCCAGCACGATAAACAGAAGCGATGGCAGTGTCCGGTCGAGGACTGCGGGAAGACCTTCTTCCTCCGGGCTACCCTCACTAAACATAGCCGCACGCACACAGACACGCGGCGTTATGTGTGCGTCACGTGTGGGAAGCGGTTTCTGGATAAGCAGACTTTGGATGAACACGGCGTCACTCATTTGCAGATAAAGCCGTTCCAGTGCCACATCTGTCTGAAGCAGCTGACCCGTCGCTCGCGGCTCAGGATGCACCTGCGAGCTCACGAGGAGGAACTCCGGCCCAAGCTGGTGCTCGTGTGCGCCGTCTGCAGCCGTGCCTTCAGGGACCACGGGGAGGCTCGGGAGCACGCGGCGAAGTCGTCAGGCTGCATAGCGGCAGTCGCCAACGAGCTGAAGGAGGAGTCGGAGACGGTCGCCGAACAGCTGTCCCCGACCAGCGGCGAAATTAGACACACCGTTAAAGTTGTTGAATCCCCGCGTCTGAGCAGGCAGATTCCCGGGGAGGTGGCCGATTCGGAGAGCGACGCGCTGTTGACAGCCCTGGAGGACTGCGCCCGGCCGTTTGTACGGGTGGTCCGGATAGAGAAGGCGTTTCGATGCGAATATTGCGAGGACGTATTCTATCAAGAAGATGCTCTCAACACCCATCGTAGCGTCCACAAAGGTGTGAAGAATCCTTTCACTTGCCACATCTGTAAAGTTAGCTTTGCGACGTATTCCAGATGCACAACCCATAAAACAACTCATGGGTTCTATAAAAGATCCTTGGCGGATGCCAAGAAGCATGCCGAACAAAGCCAAATACCTGAAGCTGGACCTTCGGCTACCGGTATACTGGGCTACGGTGGCTTCCCTGTGGTAAAACATTTCCTGTGCGAGGACTGTGGACGCTCATATTTACATTGGACGTATCTGCAAGTACACCGTCGCATGAAGCACGCCAACGAGAACTTTGTCTTCAAATGCAATCAGTGCGACGTGACGTTCCCTAACAGTTGGAGCGTCGCGTACCACAGGAAGAAACTTCACGGTAAGACCGGCCATGAGGACGGTGGGGGAGTCACCAAGATTGCCAGGGAGGACTATCGCATACCGTGCCGAGACTGCGATGAGATATTGCCGAACAAAACTGCCCTGTACAAGCACAGGAAGAACGAACATAGCGATGGACTCTTCTGCTTCAACAGGAATGAAGgTAATATCAGTACTAGCAGTACTAGCCGTACGGCGTGTTCGAAATGTGGACACAATTTCAAGCAACCGCAAGATTTGCAAAAACATCTCGACTCGGTGCACGGCCACGAGACGAGCGCGACACGGCGTCAGCGCGTCAAAATGCACGCGTGTCCGCTGTGCGCGCGCTCGTTCCGCGCGGCGTCCAGCCGCGACGAACACTTGCGCGTTCACACTGGCGAGCGGCCGTACCCTTGCGACGTGTGCGGCGTTGCCTTTAGGCGATCAACAGCAATGCGTAACCATCGCTTGATCCATACGGGCGTGCGCGCTTGGCCGTGCGCGCATTGTCCCAAGCGCTTTCGCATCCGCTCCGATCTCAGAACGCATCTTCGGTTGAAGCACCCTGCGCATTTGGTTGTTATCGAGGTACAAGGATTGAACCCGAGCACTGAAGATATTCTCCACCAGCTGAACACCAACGGCATCAACCCGGACAAGGTTCTTGAGATAACGCTCATGGCTTTCGAAAAGGGCACTACAAGTATAGTCCCACATTCGTCGCGTGCGCTCTCCAGGTTGGGGTCCGTGCCTCGTAGTCAGCTGGCCTCCTGGAAACCAACGTGTGGAATACCTGAGGAATTGCAACCGGCTCGTCGAGGCAGAGGAATTGCAAAGGAGCCCCTAAAACCGCAGTCGTATGAAAATCGCCTAGCCCAAGAACCTACGGAGTGTCCGGTCGCACTCGACGTCAGCGAGGAGGCGTTATCTGCTCTCAACGTGCAACTGATGCTCAATGACGGTGTTCTGGCGAATGGCAACGAGATGGTGCAACTGCAGCTGGACAATATACTGTCTGAGTAG
Protein Sequence: MDEPRAEPLILCLENADREVSVEIESHDNFQMFLDKAKDLLGYEIDLNSITNNQPVSLTDNIYQFLLNAEQNLSRDNIEIETFDLMVEQNPNDDLIYVLDDGTQIKASQIQFDNEDPPLDLTAEKIPFIKYADDSDENEDDNALVETTKKINIIESPVTKWSIQNLSPKCSFVNSLPFKLVCNNTSNFEAQFTKYLETNSKNSNVNATVNNANTIKSYDKNSSRRNDDFNLTREDILDMFKDAPVTSAPYQERSFADKRKHARKSDPSRMAHKTWNPKPLSCVVDSDSQMCFICRKFVDSSLEKLYLFDNEDQKLHRCSPQRRFSTQLKILCEQCLAENFKPCTIKSPTQSLKPDEYLIIKNNQQYIFQKVTSISLRDADSDYKIPEDSNDDKFEPNAFIEVSDKQGMDFVKVEIGSDGEIVTKALYEDPDSSDDVIIVQNKERDSSSDVEIVEPEIDDNIIENLDDADEDVKEFLGKYNCGVNDAIELKCRFCEKNFEDVTEVTNHCEEHKHDVEDGVVFPCPLCDYGYANLKWLRGHLKAAHDKPNDTDTKEDGKETTPSPIHSPVAKRTRSAIKKSDGPKRTDKPENIIKDEENPNKFEENESKEPELEIKMEVKQESLNSSDDEIWILQTGDDDATETLQQLLQGVKVKNENGPEVTKVHNCANCSQSFTSTTLLLEHKCVRRRGRKRKAKGGVCVPKKEDFFKRAQERPRQPSVDIDNDLLVERPRKKRNRQPTSDPQIVTCHDCNESFTSKVRLKFHMQFHESNSFLTPGGEYKCPECEDAAFPTESELFDHVHFQHDKQKRWQCPVEDCGKTFFLRATLTKHSRTHTDTRRYVCVTCGKRFLDKQTLDEHGVTHLQIKPFQCHICLKQLTRRSRLRMHLRAHEEELRPKLVLVCAVCSRAFRDHGEAREHAAKSSGCIAAVANELKEESETVAEQLSPTSGEIRHTVKVVESPRLSRQIPGEVADSESDALLTALEDCARPFVRVVRIEKAFRCEYCEDVFYQEDALNTHRSVHKGVKNPFTCHICKVSFATYSRCTTHKTTHGFYKRSLADAKKHAEQSQIPEAGPSATGILGYGGFPVVKHFLCEDCGRSYLHWTYLQVHRRMKHANENFVFKCNQCDVTFPNSWSVAYHRKKLHGKTGHEDGGGVTKIAREDYRIPCRDCDEILPNKTALYKHRKNEHSDGLFCFNRNEGNISTSSTSRTACSKCGHNFKQPQDLQKHLDSVHGHETSATRRQRVKMHACPLCARSFRAASSRDEHLRVHTGERPYPCDVCGVAFRRSTAMRNHRLIHTGVRAWPCAHCPKRFRIRSDLRTHLRLKHPAHLVVIEVQGLNPSTEDILHQLNTNGINPDKVLEITLMAFEKGTTSIVPHSSRALSRLGSVPRSQLASWKPTCGIPEELQPARRGRGIAKEPLKPQSYENRLAQEPTECPVALDVSEEALSALNVQLMLNDGVLANGNEMVQLQLDNILSE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00971680;
90% Identity: -
80% Identity: -