Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000027.1:2660492-2667917[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00077 0.059 14.2 2.9 1 23 372 394 372 394 0.98

2 12 0.014 1.1 10.2 1.5 2 23 402 424 401 424 0.94

3 12 0.17 13 6.8 0.7 1 23 428 450 428 450 0.95

4 12 3.1e-06 0.00024 21.7 0.8 1 23 455 478 455 478 0.97

5 12 0.47 36 5.4 0.8 2 23 483 505 482 505 0.87

6 12 0.22 17 6.5 0.2 2 20 516 534 516 536 0.94

7 12 0.00015 0.012 16.4 0.1 3 23 546 566 546 566 0.98

8 12 0.00016 0.012 16.4 0.2 2 20 592 610 591 611 0.94

9 12 1.1e-06 8.6e-05 23.1 1.8 2 23 635 656 634 656 0.97

10 12 1.2e-05 0.00091 19.9 0.1 1 20 662 681 662 684 0.94

11 12 9.2e-06 0.0007 20.2 1.4 1 23 690 712 690 712 0.98

12 12 0.018 1.4 9.9 2.4 1 23 718 741 718 741 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00077	0.059	14.2	2.9	1	23	372	394	372	394	0.98
2	12	0.014	1.1	10.2	1.5	2	23	402	424	401	424	0.94
3	12	0.17	13	6.8	0.7	1	23	428	450	428	450	0.95
4	12	3.1e-06	0.00024	21.7	0.8	1	23	455	478	455	478	0.97
5	12	0.47	36	5.4	0.8	2	23	483	505	482	505	0.87
6	12	0.22	17	6.5	0.2	2	20	516	534	516	536	0.94
7	12	0.00015	0.012	16.4	0.1	3	23	546	566	546	566	0.98
8	12	0.00016	0.012	16.4	0.2	2	20	592	610	591	611	0.94
9	12	1.1e-06	8.6e-05	23.1	1.8	2	23	635	656	634	656	0.97
10	12	1.2e-05	0.00091	19.9	0.1	1	20	662	681	662	684	0.94
11	12	9.2e-06	0.0007	20.2	1.4	1	23	690	712	690	712	0.98
12	12	0.018	1.4	9.9	2.4	1	23	718	741	718	741	0.78

Sequence Information

Coding Sequence: ATGGAGCACTTAACATACTGTGTGATGTGTCTGGGGACTGAAGTAAAGATATTTCACCTTAATTCTGCATTGTTAAAACTTTACAAACAGTTAATTCCAATAAATgaTGAACTTTGCACAAAACACATGCATGCATGTTATGAATGTGCATATTTGTTGCACAAATATGgagaatttaaagaaaaatgctGTAAAGCctataatattctttgtacAATCAGCCCTAAACCATTTGagGTAAACAAAGACAACCTAAAAAGTATAGATCGAAAACAAAGCAAATTAGAATCTGTACTGACGACATGTACCACATCTAATTATTACAAACCCAATCAAAAAAATGACTGTTGCAATGTAGATAATCAACTTCAAGGTGGTATGGTAAAGACTAAATCAGTTTTAAATAGAATACAAGACCAATGCAATGGAAATGTACTAAACTCAGAGAAAGATTCAGAATTATCTACAGCTGATCCAATTACTTTTGATGATTTAAGCAAtcaatctattttaaataatgacgAAATCAAAACAGATGTCAAAAGCACATTTGAACAAGATTTTGAAGATGATAATTGCCCTTTGaacatgttaaaaacaataagCTCCTACAACAGTTTAAATATAAGtgggttttatatttttaatacaaaagaaGGATGTGATTTAAAAACTACACATGTAGCTAATAATATAGTACCTCTTTTGAAGCTAGAATGCGTTGACAGTAATAATGATAGCGATTGTGAAGTTTCAAGTAAAATTCCAGTTAAAGTTGAAAGAAAGATCACAAGAATAGAAAAGAggaaacttgaaataaataagaagaataCACATAGTAAACGGagtaaaaaggaaaaaagtaaGAATAAAGCTTTCAGTGAAAGTATGAAGCTTGGTAgtgatatagataataaatgtattaaccaAAAAGGGTCTCaaaaaaatggtaaaacaaGGAAAGTAATCATAGATAAAACCACTAAAAATTATCGCTTTTCTATCAATTCAAGTATTTTTAAGGAGCACATGACTATAGTTGAATTAACTCCGGAAGATGCAAAGAACGAATTACTTCTAAGAAAGGAATcgagaaattataaaataaattcgcaTAAGTGCGATTTATGTTATCGTGGATTTATTTCAGAGGCTACATTTCAAACACATATGAAAAAACACAGTCCGATATACGGAACCCTTAAGTGCGACATCTGTCAACTGAGTTTCGCTGAGAATCGCTGCCTCGCCAATCACTGGATCGTCTGCCACACGCGAAAATTTCTTTGCAAGAATTGCCCTTATGTATGTTTCGGCGCTAATCAAGCCAGAGCTCATATACAATCACACATAGGAAAGAAGTACACGTGTAAGGAATGTGGAGAAATattcagGTTTCCAAACAGTCTCTCAACACACATGCGGTTGAGACATAGTGTGGAGCTTGTGTGTGATTTTTGTGGAAGCACGTTTGCATCACCGAAAGGATTGGACTGTCATAAACGGTTACTTCATAGAAAGGAAAAGAACGAGCATCTAGGTCCAAAATGTGAAGAGTGCAATGTACACTTCGCCTCCGAGCTGGCGTGGAAGAGGCACCGCGTGCTGTGCTCCAGACACGATGTACAcGAAGGGTGCGGGGTATGCGGCGACACGTTCTCGGACGCGAGCAGTCTGCGTGTACACTTACGCGAGCACGGCCCGCTGCCGACCACGTGGAACTGGCGCCTGCGCACCAAACCGCCCGTCGCCGCCCACCGCACCGCGCCGCAGCCGTGCGACTATTGTGACAAAGAGTTCCGTAACCAAAAGGAGTATAAAATGCACATCGCCTGCGACCATCCGCAGGTGGACGCACAGGACAGCCGCGAGGGGTTCCTCACGACGTCGCCGATGAAATGGGTGTGCGAGGTCTGCGGGAAGATGTTCAAACATAATTCTCTATTCATCAGCCACCAACGCAAACACACGGGCGAGAAGCCGTACAGTTGTCCCGACTGCGGCAAAGCGTTCAAGCGCGCGGACGCCGTTAAAGCGCACCGTCCACTCCACACCAACGAGTACATGTTCAAATGTCACCTGTGCGATAAGGCGTACGGGGACAGAGGCAAGCTTAATAGACATATTAAAgGTCACTTGGGCATCCGTCCGTACAAGTGTCCTTACTGCGATAAATCCTTTCTGTACCAGTGCGTGGCGAATGCTCATACCAGGTACGTGCACTGTAAGGAACCGTATCCCAAGAGGAACAGAAGTAAAAAAAACCGGTAA
Protein Sequence: MEHLTYCVMCLGTEVKIFHLNSALLKLYKQLIPINDELCTKHMHACYECAYLLHKYGEFKEKCCKAYNILCTISPKPFEVNKDNLKSIDRKQSKLESVLTTCTTSNYYKPNQKNDCCNVDNQLQGGMVKTKSVLNRIQDQCNGNVLNSEKDSELSTADPITFDDLSNQSILNNDEIKTDVKSTFEQDFEDDNCPLNMLKTISSYNSLNISGFYIFNTKEGCDLKTTHVANNIVPLLKLECVDSNNDSDCEVSSKIPVKVERKITRIEKRKLEINKKNTHSKRSKKEKSKNKAFSESMKLGSDIDNKCINQKGSQKNGKTRKVIIDKTTKNYRFSINSSIFKEHMTIVELTPEDAKNELLLRKESRNYKINSHKCDLCYRGFISEATFQTHMKKHSPIYGTLKCDICQLSFAENRCLANHWIVCHTRKFLCKNCPYVCFGANQARAHIQSHIGKKYTCKECGEIFRFPNSLSTHMRLRHSVELVCDFCGSTFASPKGLDCHKRLLHRKEKNEHLGPKCEECNVHFASELAWKRHRVLCSRHDVHEGCGVCGDTFSDASSLRVHLREHGPLPTTWNWRLRTKPPVAAHRTAPQPCDYCDKEFRNQKEYKMHIACDHPQVDAQDSREGFLTTSPMKWVCEVCGKMFKHNSLFISHQRKHTGEKPYSCPDCGKAFKRADAVKAHRPLHTNEYMFKCHLCDKAYGDRGKLNRHIKGHLGIRPYKCPYCDKSFLYQCVANAHTRYVHCKEPYPKRNRSKKNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00971562;
90% Identity: iTF_00971562;
80% Identity: -