Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000002.1:6270104-6288300[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0098 0.75 10.7 0.7 1 23 546 568 546 568 0.97

2 11 2.7e-05 0.002 18.8 3.4 1 23 584 606 584 606 0.97

3 11 0.00046 0.035 14.9 2.6 1 23 612 634 612 636 0.97

4 11 7.6e-07 5.8e-05 23.7 3.6 1 23 641 663 641 663 0.99

5 11 1.2e-05 0.0009 19.9 0.2 1 23 669 691 669 691 0.93

6 11 6.3e-08 4.8e-06 27.1 0.1 1 23 697 719 697 719 0.98

7 11 4e-06 0.00031 21.4 1.8 1 23 725 748 725 748 0.96

8 11 0.00069 0.052 14.4 3.6 1 23 754 777 754 777 0.95

9 11 5.6e-05 0.0042 17.8 1.7 2 23 784 805 783 805 0.97

10 11 1.9e-05 0.0014 19.3 1.0 1 23 811 833 811 833 0.97

11 11 0.0027 0.21 12.5 0.1 1 23 839 863 839 863 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0098	0.75	10.7	0.7	1	23	546	568	546	568	0.97
2	11	2.7e-05	0.002	18.8	3.4	1	23	584	606	584	606	0.97
3	11	0.00046	0.035	14.9	2.6	1	23	612	634	612	636	0.97
4	11	7.6e-07	5.8e-05	23.7	3.6	1	23	641	663	641	663	0.99
5	11	1.2e-05	0.0009	19.9	0.2	1	23	669	691	669	691	0.93
6	11	6.3e-08	4.8e-06	27.1	0.1	1	23	697	719	697	719	0.98
7	11	4e-06	0.00031	21.4	1.8	1	23	725	748	725	748	0.96
8	11	0.00069	0.052	14.4	3.6	1	23	754	777	754	777	0.95
9	11	5.6e-05	0.0042	17.8	1.7	2	23	784	805	783	805	0.97
10	11	1.9e-05	0.0014	19.3	1.0	1	23	811	833	811	833	0.97
11	11	0.0027	0.21	12.5	0.1	1	23	839	863	839	863	0.94

Sequence Information

Coding Sequence: ATGTACCAGACCTGCTTTGTATGTGACGCTAACAATGTTGGGTTTCGAAATGGATTTAATCTATTTTCGCAAGATACCACTCTTCAATCGGGAAAAAAGATGATAGAAGTATTGAGTGAGATATTGGATAAGCCTATCCACGAAGAGAACGTTCATTCTAAGATTATATGTAAAAAGTGTCACAAATTTGTGTCCGAGTATGATTCTATCCAAATCAGAATGCAAGTGATAAAGCTGGACCTTTTATCACACTTCAAAACCACTCTGCCGCGCCACAAATTGAGCTACGACTCATACAACCAGGAACCAGTGATAATCCACGTACCCGCATTGAATTGTTCGGAAATAAAATCGGAACCCAAGAAAAAGCTAGTATTACCCGCGTCTAAGCTGCAACCGGTACCGGCAGATTTTGTTTTGAGACCCGGAAAATGGTTGACGAGTAAACATACTGCTAGTAAGccAATCATCAATCAAGTAACGCTACCGTCATCAACGTCTACCCTCAACTTAAAAGTGACCGTCGGTTCGTCTGTTCTCACACAGAGCATCAAGACAACGAATgcaattggaaataaaataatatccttaACAAACAGTCCTAATAATTCAGAAAACTACGTATTGGCACAAAAGGCAGATAATGAAAGCAGCAGTTCAACTGCAGATTTAAAAATAGACGGGAACACGCTTCTGCAAACCATTGAAACTCCAATAAGTCTATCGTCACTAAATTATTCATCAAACGCTAATATATCGTCGGCTAAAACTAACAATTCCATAATAAGCTTTAATGTGAAGTCGTTGCCGAAGGATTTTCTTTCTTCCGCGGTATTTAATAAGGTCGATGTGAATGAGCTGGTCGAGcttgaaatgaatttaaagaAGGAAATTCAAGAGAACAGTGATGCAGAGAACAACGACGAACAACCCATGGAAATAGATGAAGATTGTTCGTTGGCTGTGGCGGTTAACAGTGGCGAAGAGAAATCCATTAACAAAGATTCAGACCAGAACGAGTCGGACAAAACCAAGGACTTCCTCGACAACCTCCTTCCCGGCCTGACGTCCAACGAGGACACGACCGACGATGACATCGAGAGCAAGTTTATCGTCGGCAAACTGGAGATACTCAACGACAGGGAGGACGATGGAGATGGCCCAACAATCCTGATGGATGGTGAGAACGGGTCCATCATAAGGCTGGTGTCTGGGCAGAAGTTTCTGTACGGCGACAGCGAGATATCGTTAGTGGTGCCCGAGGACGTGCAGGGCTGTGATAACGAGAACGGAGACAATCAAGATTCAAATGATGAATCGCAAATAGAACTTCAAGTCTCCGGCGACGAAGAAACGGCGAACGCTATTATTGCAGCCGCTCAGGAACAAGGTGGTGCTTTCATAAAAGTGGAATCTGGCGAGATGTACAGAGTGAAATCAGTACAGAGCAAGAAGACTGATGACACAGTGACCAGTGTTGATCTGCAACCGGCTTTGAACTCGATGGTAAAGCAAGAAGAAAACGGTCAATTCAAATGTTTGCTCTGTGAGAACAACGAGAAGAAAGCAGACTCGTTCGTCGAAGACGCGGAGGCCACGATGCAGCACTTGAAGAGCGAGCACGCAGCGCGCATCTACATCTGCGGGCGGTGCGGGCACGTCGTGAGGAAACGGAGCGAGTACGTGACGCACCTAGAATCGCACGCAACAAAGTcgaataatgttttacaaacGGACAACTCCAAAACCCATGAATGTACCATATGCAATAAGAAATACAgCTCCCGAACGCTACTGTCGAAGCATATGAATCTCCATAACGAGGTGAAGTCTTACAGTTGCAACGTTTGCAACAAATCCTTCGCGTCCAAGTATACCCATCAGTCCCATCTCAAAATACATATGGAGCGAACACGCCCCTACAAGTGCAAGCAATGTGGCAAGTCATTCTTCACGCAGCAGAATCTCAACCAGCACGAGAAAACACACTCCGGGGTCAAggatttcatttgtaatacatgCGGCAAAGCGTTCGCGTCTCAACATAATTTGGAGGTTCACGGAGTAGTCCACTCGGGGAACAAACCGTTCGTGTGCGGAGACTGCGGAAAAGCGTTCGCGCGACGCGCCGAACTGCGGGATCACATGCGAATACACACCGGTGAAAGGCCGTTCTCGTGCGACATCTGCGGCGCTAGCTTTACCCAGCGGTCGAACCTGCACTCCCACAAGCGCGCAACGCACATGGACGACAAGCGCTACCACTGCACGCAGTGCCCGAAGAGGTTCAAACGCCGCAGGTTGTTAGACTACCACATAAAGGCGTCGCACACGGGCGAGCGGCCGTTGAAATGTGAGATTTGCAAATCGACCTTCGTGTACCCGGAACACTACAAGAAACACATTCGAATACACAGCGGGGAGAAGCCGTATGTCTGCGAGGTTTGCGGCAAGTCGTTTAACTCGCGCGACAACCGCAACACGCACCGGTTCGTGCACAGCGACCGCAAGCCGTACGAGTGCGTTGTCTGCGGCGCCGGTTACATGAGGAAACAACTGTTGTACCAGCATATGAACACCACCGGCCATTTAGCAGAATCAATAGTAGTCAATCAGCCCAGAGTTGTGAAGGGACCTAAGaatatatacgAAGCCACCGAAGAGTTGCAACTACATACAGAAGACGGCAAACATATTGCGGACACAGACGGCGcggcaaaattatttataactgaaGATAAAAAACTCATCTTTCAAGATGCTAAATCAATAAACGTCGTACAAGAACCTGACGAATCGACGCTCCTTACGTTACAAAACACTGATGCCAATTACAAGACTGATGGTGCTATGTTGGAAGGAATCACAGCGGAGCAGTTGGAACAAGTGCAGTTGGTGACTACCGACGGCGCCGGCACTTCGCTTCGGTTGGTGCAAATTCAACTGTCCGATGGCAACAACGGATGGCTCGCGATAAACCATTGA
Protein Sequence: MYQTCFVCDANNVGFRNGFNLFSQDTTLQSGKKMIEVLSEILDKPIHEENVHSKIICKKCHKFVSEYDSIQIRMQVIKLDLLSHFKTTLPRHKLSYDSYNQEPVIIHVPALNCSEIKSEPKKKLVLPASKLQPVPADFVLRPGKWLTSKHTASKPIINQVTLPSSTSTLNLKVTVGSSVLTQSIKTTNAIGNKIISLTNSPNNSENYVLAQKADNESSSSTADLKIDGNTLLQTIETPISLSSLNYSSNANISSAKTNNSIISFNVKSLPKDFLSSAVFNKVDVNELVELEMNLKKEIQENSDAENNDEQPMEIDEDCSLAVAVNSGEEKSINKDSDQNESDKTKDFLDNLLPGLTSNEDTTDDDIESKFIVGKLEILNDREDDGDGPTILMDGENGSIIRLVSGQKFLYGDSEISLVVPEDVQGCDNENGDNQDSNDESQIELQVSGDEETANAIIAAAQEQGGAFIKVESGEMYRVKSVQSKKTDDTVTSVDLQPALNSMVKQEENGQFKCLLCENNEKKADSFVEDAEATMQHLKSEHAARIYICGRCGHVVRKRSEYVTHLESHATKSNNVLQTDNSKTHECTICNKKYSSRTLLSKHMNLHNEVKSYSCNVCNKSFASKYTHQSHLKIHMERTRPYKCKQCGKSFFTQQNLNQHEKTHSGVKDFICNTCGKAFASQHNLEVHGVVHSGNKPFVCGDCGKAFARRAELRDHMRIHTGERPFSCDICGASFTQRSNLHSHKRATHMDDKRYHCTQCPKRFKRRRLLDYHIKASHTGERPLKCEICKSTFVYPEHYKKHIRIHSGEKPYVCEVCGKSFNSRDNRNTHRFVHSDRKPYECVVCGAGYMRKQLLYQHMNTTGHLAESIVVNQPRVVKGPKNIYEATEELQLHTEDGKHIADTDGAAKLFITEDKKLIFQDAKSINVVQEPDESTLLTLQNTDANYKTDGAMLEGITAEQLEQVQLVTTDGAGTSLRLVQIQLSDGNNGWLAINH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00887606;
90% Identity: iTF_00971548;
80% Identity: iTF_00971548;