Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000003.1:3606907-3610775[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0007 0.053 14.3 2.4 1 23 138 160 138 160 0.98

2 12 0.00013 0.0099 16.6 1.1 1 21 165 185 165 186 0.94

3 12 0.0019 0.14 13.0 4.3 1 23 215 237 215 237 0.98

4 12 5.6e-07 4.3e-05 24.1 1.9 1 23 247 269 247 269 0.98

5 12 1.7e-06 0.00013 22.6 2.5 1 23 275 297 275 297 0.99

6 12 1.4e-06 0.00011 22.8 4.8 1 23 303 325 303 325 0.97

7 12 7.3e-08 5.6e-06 26.9 0.7 1 23 331 353 331 353 0.95

8 12 3.8e-06 0.00029 21.4 1.6 1 23 359 381 359 381 0.98

9 12 5.9e-07 4.5e-05 24.0 0.1 1 23 387 409 387 409 0.98

10 12 0.0006 0.046 14.5 6.9 1 23 415 437 415 437 0.98

11 12 2.9e-06 0.00022 21.8 1.1 1 23 443 465 443 465 0.99

12 12 0.00018 0.013 16.2 0.5 1 20 471 490 471 493 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0007	0.053	14.3	2.4	1	23	138	160	138	160	0.98
2	12	0.00013	0.0099	16.6	1.1	1	21	165	185	165	186	0.94
3	12	0.0019	0.14	13.0	4.3	1	23	215	237	215	237	0.98
4	12	5.6e-07	4.3e-05	24.1	1.9	1	23	247	269	247	269	0.98
5	12	1.7e-06	0.00013	22.6	2.5	1	23	275	297	275	297	0.99
6	12	1.4e-06	0.00011	22.8	4.8	1	23	303	325	303	325	0.97
7	12	7.3e-08	5.6e-06	26.9	0.7	1	23	331	353	331	353	0.95
8	12	3.8e-06	0.00029	21.4	1.6	1	23	359	381	359	381	0.98
9	12	5.9e-07	4.5e-05	24.0	0.1	1	23	387	409	387	409	0.98
10	12	0.0006	0.046	14.5	6.9	1	23	415	437	415	437	0.98
11	12	2.9e-06	0.00022	21.8	1.1	1	23	443	465	443	465	0.99
12	12	0.00018	0.013	16.2	0.5	1	20	471	490	471	493	0.94

Sequence Information

Coding Sequence: ATGacgaaattagaattatcaacGACTTGTCGCAGTTGTATGATGAGAGACATAGAATTGGTTGATTTGTTTGTCCCTCTTAATGACGATAATTGCAATCTGCAGCTAGCTGAATTACTTATGACGACGGTTTCTATTAAgGTTAGCAAAGAAGATGGATTGCCTCAAAAGCTGTGTAATAAATGTGTATGTTTTCTTCATTCTGTACATATGTTTCGCAATAAAGCCTTATCAGTCGATAGTGAACTGAAGAAATTGTTTCTTCCTCAGTCAGATGTCAAAgatgaaattgaattaaaatgtgAAAGTATTGCAGACTACTTGGACGATTACAATGATTATACCCATAGTGATGTTATTCCTAAACAAGAAACTCAAGACAGTGATTTTAAAGAAGAGAATCAGGAACTGTATGTGTGTAATGTGTGCCATAAACCTTACACTATACAGAGTCGTTATTTAAAACATCTGTCCACTCATTTAGAACCTAAGTTCTTCTGTAAAGTATGCAACAAATCATTCCAAAAGGAGACCTCATTAAACaggcacataattaaaaaatgcaaaaatgcTACAGCCCTCTTTGGTTCTTTGCAAAATGCTACAGTATCAGTGAAGGCAGAAAAGGATGAAGATGGAGTGTTTAGATGTATGCTTTGTCCGCTGACATTTACCAAGCACAGATCTCTTTCATCACATTTAAAGAAACACAAAACGAAACATAAACCTAGAGTTATGTATAGATGTGACTATTGTAGTAAAGAGTTTACAATGAAGTCTGCACTTAAAAGACATATTAAGCTTCACTCATCTAACCAAGCTTACCAGTGTTCAATGTGTTCCAAGAAGTATTCTAGACAAGATCAGTTGGAGGAGCATACGAGGAAACATACTGGACTTAAGCCACATCCCTGTCCACACTGTGATAAAGCCTTTTCTCAATTATGCAGTTTGAAAGATCACATTAGAACACACACAAAGGAAACGCCATTCCTATGCCCTCAGTGTGGCAAGGGTTTTACAAACAGCTCCAACTTAAGACAACATCTTTTGAGGCATTCGGGCCATAAGGCATTTTCTTGCAACCTTTGTCCTAAGACATTTTACACAAAAGGTCAAATGAAGACCCACATGGGAACTCATACAGGCGCTCATCGGTACGAATGTCCCGACTGCGGCACCGCCCTCACTACACCCAGTTCACTAAAGAAGCACCGCCTTATACACCTGGGAGTCAAGCCGTACGCTTGCGACACTTGCAATTACAAGTTCACGTGTAAAGATCACCTGAAGCGTCACCAGCGCATCCACACCGGTGAGAAGCCGTACCGGTGCGCGCACTGCGAGCGCGCGTTCGCGCAGAGCAACGACCTCGTCAAACATCTGCGCTCGCACGTCGGACAGAACATCTACCAGTGTACCATATGTGAAATGAAGTTCCGGCTACTTAGCGAGCTGAAACGTCACTATCCGATTCACTACATCAACGGCAACAACATTAGTCAACTGGCTACCGACCAATCGGTTCTGCTGATGGAAGGACAGCCCTTGCAACTCGAGAAGCCGCCGGAAGACATCACCAGTATGGACAAACACACCGACAATCAGATCACTATAACGTTTAATAGCAACGTGTTGGACAAAAGTATTGCCGGTgacattactattaatatatcgCCGACTAAAACTTAG
Protein Sequence: MTKLELSTTCRSCMMRDIELVDLFVPLNDDNCNLQLAELLMTTVSIKVSKEDGLPQKLCNKCVCFLHSVHMFRNKALSVDSELKKLFLPQSDVKDEIELKCESIADYLDDYNDYTHSDVIPKQETQDSDFKEENQELYVCNVCHKPYTIQSRYLKHLSTHLEPKFFCKVCNKSFQKETSLNRHIIKKCKNATALFGSLQNATVSVKAEKDEDGVFRCMLCPLTFTKHRSLSSHLKKHKTKHKPRVMYRCDYCSKEFTMKSALKRHIKLHSSNQAYQCSMCSKKYSRQDQLEEHTRKHTGLKPHPCPHCDKAFSQLCSLKDHIRTHTKETPFLCPQCGKGFTNSSNLRQHLLRHSGHKAFSCNLCPKTFYTKGQMKTHMGTHTGAHRYECPDCGTALTTPSSLKKHRLIHLGVKPYACDTCNYKFTCKDHLKRHQRIHTGEKPYRCAHCERAFAQSNDLVKHLRSHVGQNIYQCTICEMKFRLLSELKRHYPIHYINGNNISQLATDQSVLLMEGQPLQLEKPPEDITSMDKHTDNQITITFNSNVLDKSIAGDITINISPTKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01082658;
90% Identity: iTF_00971544;
80% Identity: iTF_00971544;