Murs000520.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megathymus ursus
Gene Symbol
-
Assembly
GCA_003671415.1
Location
PDGT01000093.1:493929-503459[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 53 0.0069 0.53 11.2 1.5 1 23 31 53 31 53 0.99
2 53 3.1 2.4e+02 2.8 0.0 3 23 82 103 80 103 0.90
3 53 0.15 12 7.0 1.4 1 23 123 146 123 146 0.96
4 53 0.0042 0.32 11.9 0.8 2 23 153 175 152 175 0.94
5 53 0.0063 0.48 11.3 2.8 1 23 179 202 179 202 0.94
6 53 0.16 12 6.9 0.6 3 23 206 227 205 227 0.94
7 53 0.79 60 4.7 0.2 2 20 233 251 232 253 0.91
8 53 0.00059 0.045 14.6 2.2 1 23 314 337 314 337 0.97
9 53 6.7 5.1e+02 1.8 0.1 3 23 366 387 364 387 0.93
10 53 0.00065 0.05 14.4 0.5 1 23 409 432 409 432 0.93
11 53 0.00027 0.02 15.6 1.9 2 23 438 459 438 460 0.94
12 53 0.014 1.1 10.2 1.3 1 23 496 519 496 519 0.94
13 53 0.0003 0.023 15.5 3.8 1 23 523 546 523 546 0.97
14 53 0.47 36 5.4 0.6 2 23 553 574 552 574 0.97
15 53 4.6 3.5e+02 2.3 0.9 1 10 580 589 580 590 0.96
16 53 0.12 9.2 7.3 0.3 1 23 631 653 631 653 0.95
17 53 0.33 25 5.9 1.9 2 23 681 703 680 703 0.93
18 53 0.16 12 6.9 1.1 2 23 724 746 723 746 0.94
19 53 0.083 6.3 7.8 5.7 1 23 751 773 751 774 0.96
20 53 0.38 29 5.7 1.3 1 23 778 801 778 801 0.91
21 53 0.065 4.9 8.1 2.2 2 23 804 826 803 826 0.95
22 53 0.92 70 4.5 0.8 2 20 832 850 831 852 0.92
23 53 0.02 1.5 9.7 2.9 1 23 900 923 900 923 0.96
24 53 0.00024 0.018 15.8 0.3 1 23 995 1018 995 1018 0.92
25 53 7.7e-05 0.0059 17.3 0.3 1 23 1023 1046 1023 1046 0.95
26 53 0.0002 0.015 16.1 3.2 1 23 1051 1074 1051 1074 0.94
27 53 0.0033 0.25 12.2 0.5 2 23 1080 1102 1079 1102 0.93
28 53 0.035 2.7 9.0 1.0 1 17 1106 1122 1106 1123 0.90
29 53 0.0013 0.1 13.4 1.5 1 23 1164 1186 1164 1186 0.96
30 53 0.034 2.6 9.0 0.0 3 23 1215 1236 1213 1236 0.91
31 53 0.007 0.53 11.2 0.6 3 23 1258 1279 1257 1279 0.98
32 53 4.5e-05 0.0034 18.1 0.7 1 23 1284 1307 1284 1307 0.96
33 53 0.012 0.95 10.4 0.4 1 23 1312 1335 1312 1335 0.98
34 53 0.099 7.5 7.6 3.6 2 23 1338 1360 1338 1360 0.96
35 53 0.37 28 5.8 4.0 2 22 1367 1387 1366 1387 0.96
36 53 0.018 1.4 9.9 2.7 1 23 1441 1464 1441 1464 0.93
37 53 0.0034 0.26 12.2 0.3 2 23 1537 1559 1536 1559 0.94
38 53 3.2e-05 0.0024 18.5 0.7 3 23 1566 1587 1565 1587 0.94
39 53 0.013 0.96 10.4 3.6 2 23 1592 1614 1591 1614 0.93
40 53 0.0037 0.28 12.0 2.7 1 23 1619 1642 1619 1642 0.95
41 53 2.5e-05 0.0019 18.9 4.9 1 23 1646 1669 1646 1669 0.97
42 53 0.00079 0.061 14.2 0.3 2 23 1676 1697 1675 1697 0.96
43 53 0.00018 0.013 16.2 1.6 1 23 1703 1725 1703 1725 0.98
44 53 0.83 64 4.6 0.1 1 23 1800 1823 1800 1823 0.96
45 53 0.042 3.2 8.7 0.1 2 23 1854 1876 1853 1876 0.94
46 53 0.015 1.1 10.2 1.1 2 23 1899 1920 1899 1921 0.94
47 53 0.007 0.53 11.2 1.5 1 23 1926 1949 1926 1949 0.95
48 53 0.099 7.5 7.6 1.1 1 23 1954 1977 1954 1977 0.94
49 53 0.01 0.79 10.7 1.0 2 23 1983 2005 1982 2005 0.91
50 53 0.00048 0.036 14.8 0.1 2 23 2013 2035 2012 2035 0.97
51 53 0.11 8.2 7.4 0.1 2 23 2042 2063 2041 2063 0.96
52 53 4e-06 0.00031 21.4 1.3 1 23 2069 2091 2069 2091 0.94
53 53 4.1e-05 0.0031 18.2 3.1 1 23 2097 2120 2097 2120 0.98

Sequence Information

Coding Sequence
ATGCATCGAGATGCAAATCGACGGCGAAGACATAACCTTCAGATATTGTTCAACAATACTACAGTGATACCTTTCAAAGGACGAGGAAGGTTTAAATGTTTCTATTGTGGAACAGCAATAGTAGACTACCAGGAATTTAGACAACACACTAAAACACATAATCCTTGCTCAATAAACGATCGAgctataaaattagtaaaaacagATGAAGCGGAAGTGAGAGTCGATGTTTCAACTGTAATTTGTGAAATATGTAACGAATCTAAAGCTAATTTCGAAGATCTAATCGCACATTTAATTGACGAACACAATGTCATGTATgacacagaaataaaattattgattatgaaGTACAAACTCGAAGactttaaatgtgttttatgcGATCAAAAATGTAACACTCTCATTGCCTTGCTAACTCACGTGAGCAAATCTCATGACACATCTAAACTCCTGTCCTGCTCCGAATGTCGGCAGAAGTTTAAGAAAAAAGGCGAATTAGATGCGCATACAAGAGCTtatcataaaaaagaatataattgcACAAAATGTTCCTTAAGTTTTTCATCGTATTTTGAGCTGCAAAACCATAAAAGTAATTCTCATATCGCaatgtgtaatatttgttttagacCTTTCGCTACGGCTAAGAAAAGGttacaacatttaaaactagAACACGGGAATGATGATTTGCGGTGTggtttttgcaataaaatcgTAAGCACTAAAATTGGTTTTCTGAAACATGCTTCCAAGTGTATCGAGATGGAAAAGAAACATTCACGGCAGGATCTAGAAGATTTTATAGGTTTCAACATTGACGTTTTAAATACTGAACGCGTTATTAAAAAGGCGAGCGTCAAAACAATACGCAATAACATAGCATGTCTTCTCAACAATTCTACAGCGGTACCGTTTAAATTCTTCATGAATAGATTTAGATGTTTCTATTGTCCCAAAGATTTTAATGATTGCGATGGTCTAAAGGAGCATACCAAAATAGAACATCCCTACTGCGATACAAAGTTTAAGTGTATGTTAATGCGAAATCGAGAATATGGGAAAATTAAAGTTGATGTATCCTCACTGTTTTGTAAACTCTGTTTCGAGCCCATGAAAGATTTAGATTATCTTGTAGATCATCTGATTTCCGAACATAAGTCAAATTTCGATAAAACTGTAGATAGCAACATACAAGGGTTTTCACTCATCAGAGATAGTTATCTCTGCCCCTTCTGCGGTGAAGTATTTAGATATTTCAGCAATGTACTCAAACATATTAGTCAGACTCATTCTAATAATAATGCAGTTTGCATGCATTGTGGGGCGACTTTTCGTAACCTGCCAAACTTAAGAGCACACATCTACAAACATCATAGACAAACAAAACCTTCTAAATATAGATGCGCGAAATGTAAGCTCCATTTTAGTTGTAAAAAAGATTATCAGACCCATTTCGGTAAGGTACATGGCAATAAGATGTTCGACTGTCCGACATGTCAGGAGAAGTTTTCATCTGCACACACTAAAGATAGGCACATGATAAATGTGCATCAATTAGGGCACAAGTGTTCACACTGTGGAAAGCTGTTCCCAAGAAACTCGCAAATGGTGGACCATGTTAGACGTACTCATTTAAAGGAGAAAAACGTTCAGTGTCAAATTTGCCGCGAGTTATTTTTTGATGTGCACGTGTTGCGATTGCACATGGTTACGCATTGTGGTGAGCGCAAGTTTCAATGCGATGTTTGTAGCAAAAAGTTTCTTTGGAAGAAAAATCTTATTGATGTTATCGGCGCGGCACAGACGCAAAGTTTTAATAGAAGAAGGAATCTACAGATATTGTTCAACAACACGACCTTGTGTCCTTTTAAATGGCGGGGCAAATACCTGTGTTTTTATTGTGGAGAGGATATGCCAAACTACGAAGAACTAAAGAAACATACAAAAGGGCATGGCCCTTGTACCGACAGAGATAGAGCTATTAGATTAGTTAAAGCCGCTGATGCTGAAGTGAAAATTGACGTTTCAGACATCACATGCGAGATATGTAAAGAATGTTTTGTCAGCTTTGATGAAATTGTCGGTCATTTGAAACACAAACACGAATTGCCTTACGATACTGGTGTCAAGCTTTCTTTGGTTATATACCGTCTTATAGATCTGCAATGTTTATTCTGTGAAGAGAAAttcaattactttaataaacttATCAAACACGTCAACAACATGCATCCTAGTGAAAGTTTCGAATGTTGTAAGTGTCTACAGATGTTCAATAAGAAACGGGACTTAGATGCTCATACGCGGATGCATCATAAAAAAGACTATAGATGTCTTAAATGTTCTGTAACATTCGCTTCATATGCCGTTTTCAAGAAACACAATTTGAATTCTCATATCTCTACGTGTAAtgtttgtttcaaaaattttgcaTCCTTAAAGAAACGCTTGAAACACATGAAGCAAGAACATGCAAATGATATGCTCCAATGCGGTTTTTGCTCAAAAACAATGAGTACAAAACAAAGCTTTTTACGTCACGCGACCAAATGTAACTTACGAATTAACAGCTCTGAAAAAGTAATCGTTGACGATGAGGATAGAAAGCCGTCTGTCattcaaataagaaataatgttgcttgtgtattaaatatgtcAACTGCCATTCCTTTCAAGTACTTTATGAGTAGATTTAGATGTTTCTACTGTCCTAAAGATTTTTATGAATGCACTGATTTAAGAGAACACACGGTGACAGAACACCCGCATTGTGACATTAAGCTTAAGAGCATGAAATTACGTAACAGACATGACGggtgtataaaaatagatatctCATCTCTGTCTTGCAAGTTATGTTTTGAACCAATACACGATTTAGAGGCCTTAATAGATCATCTTATTTTCAACCATAAGGCGAACTATGATAAGTCCATCGACTGTAACATGCAGccttatagattaattaaagacaatttCTCGTGTCCTCTATGTGGTGAAGTTTATCGATACTTTAGTTCGTTGCTAAGACATATCGGTAATTTCCATACGGACAATAAGTATATTTGTGTTTACTGCGGCAAGTCATTGAGGAATGTTTCGAATTTAAGGGCACATGTTTCCAGTAAGCATAATACTGCCGTTCATAAATGCAGTAAATGTGATATGGAGTTTAATTCTAATAGTCATTTACAAACTCACTTAGGCAGCGCACACGGGATGAAGGTGATTCAATGTTCGGAATGTCAAGAAAAATTTATATCCAACTATAGAATGCAGAGGCACATGGTCAATGTGCACAGATCTGGACATAAGTGCACATTTTGCGGGAAGTTATTTACTAGAAACTCGCTAATGAAAAATTTCTTTGCAGATGAAATCGCGCATAGCAAGTACGAGAACTACACCTCTGAGAGAAGgaggaaaaatttgaaaatcctCTTCAACAATACATCTATTATACCGTTTAAATGGCGTGGCAAGTACTTGTGCTTTTACTGCGGTAAGAATTACGCAGATTATCCTGAATTTAAAAAGCATACTAAATCTCACGGTCTTTGTACCACTAAGGACTATTCTCTTAAACTTGTCAAAGGGTctcacaatgaaataaaaatagatatttcagATATGAACTGTGAAATTTGCAATGAACCATTTACCTCCCTAGATGAGATAATCAGTCATCTAATAGGAAAACATAGTCTGGAATATGACAAATCTATTGTTATTGCTTACCAAGAATATCTCTTGGCAGATTCACTATGCCAATTTTGTGGagaacattttgaatattttggttATCTTATCACCCATATAAACACAATTCATCCACAAAACTGTTTCATGTGTGATGACTGCGGACTTACCTTCAATAAGAAGAGAGATTTGGCGTATCATATAAGGCAAAATCACCGTAGAGGCGGCTACCCTTGTGACGAGTGTTCAGATGTATTTGAATCTCAAGGATTGATGCGAAAGCATAAAAATACCTTTCATTTTAGAAAGTGCAAATCCTGCCATTCTAGGTTTGCGTCATTCACTCTTCTCCAGAAACATATCAAGTTAGAACATTCTGTTACTGCCATTAAGAAATGTCCACATTGCGCAAAAGAATGTCACTCAAGACAGGGTCTGATGCAGCACTTACGGACTTGTAAAGTCAAAATGATTGTTAAAAGAGACAAGCCAACTACTTTTCCATCAAGAATGTTATTAATGCCTAGAAAGACGCAGAACATATCGCAAATTCGTCAGAATATTGTATGTGTACTGAATATGTCAACAGTAATACCGTTTAAGTTCTTTGCAAAATTTTCTTGCTTTCATTGCTCGAAAAAATTTACTGAATTCGAAGAATTAAAGGAGCACACGGCGTTAGAGCATCCTGTTTGTGACATGAAATCTAAATGCATCATAAAGTGTAAAGGAGAACGTACATGCGTGAAAATTGACGTGACGTCATTAGCGTGTAAAATCTGCTGTCAGTCGATGGAAGATCTAGATGCTTTGATCGATCATTTAATTAGTAAGCACAAAGCAAATTACGACAAGTCGTTGACCGAATGTTTTGAGCCTTTTAAGTTAGTTAAAGACAATATCCCCTGCCCTCACTGTTCGAACATGTTCAGATATTTCGCTACCCTTATTAGGCATATCAACGCAGAACATTGTAACAGCAAAAGGATATGTGATTTTTGTGGTCGATGTTTTAAAAATGCTGCCAATTTAAACGTCCACATTATCTATACGCATACTGGCTCATGCGAATGCGACATTTGTGGTCTTAAGTTCAAGAATCAGTGGTGTTTGGGTCGACACAAAGCAAAGAGTCACGACGCAAAAGATTTTAAATGTCCCAAATGTCCTGAACAGTTTCAGTCTCAATATCACAAGCAGAAACACTTGATCCAAGTTCATGATATCGGACACAAGTGCAGCTACTGCGGACGCATGTTTACGCGAAACTCATTCATGAAAGATCATATACGAAGGACGCATCTGAAAGAGAAGAACGTGCCATGTTCCGTTTGCAATGAGAAATTCTTCGATAACTATTTGTTGAAACTTCACATGGTGAAACACGATGGAGAAAGAAAGTTCTCATGCAGTGTCTGTAGCAAGACCTTTTTGAGGAGAAGCAATTTGAGTTCTCATATGGATATGCACAAAAAATATGGGCACGTTCAAGAGCATAAAAGGGAGGACTCCGTTAAGAAGAAAAGTATGTTTATAAAAGGGACTAATTTCTTTGCAGGTGCCAAATACAATTCGGTGGAGGATAAATATAAGAAACGGGAATTGGCACGTAAGCTATTGTTGAAACGACGCAATGTCGAATATGTGTTGCAGTATGGCAACGTAACACCCTTTATGTGGTACAAGGGTAGATATAGATGTTTTTACTGCGCGGAGCCCATGAAAGATCCCGTGCTGTTAAGAGAACATACGGCCAAAGTGCACCAATTCGCTAATTTAGAGCTGGTAGTACACGATAGGACGAAGAATAATAGAAACAGAGATGCAGCAGTGAAAATAGACGTTACGGATATTTCCTGTAAGCTTTGTCCTCAAGCGGTGAACAGTTTAGAACAATTAATCCATCATTTGATCATAGCTCACGATGCGGAGTATGATGTGAGTGTACCAAACTGTCTTCTACCTTTTAAGTTGGATAGAGACCATCCTTCTTGCCCAATTTGCAATCTTCAATTCGTCTTCTTCGAATATCTTTTACGTCATGCGAACAAACACCACTTGGCTCACGACTACATTTGCGATGTTTGCGGAACTAGTTTCCAAGGTGAAAATCACCTAAAAATGCATAACAGATATTATCACAGGGAAGGCGGTTACACATGTGAACACTGTGGGCTTAGCTTGGCTACGTTGTCAAAGAAGACACTTcatgaaaaaaatgtacatatgatAAACCTTTCCACGTGTCCTCATTGCCCCGAAACGTTCAAAAGTCCATACTTTAAGAAACTCCATTTGGCTAATGTGCACGGAGTTGAGGAATTGAAAATCAAGTGCCCATACTGTCCGAAAGTCTATCCGCAGGAAAGCATCATGTCACGTCATATGAGGCGAGTGCATTTACGAGAGAAAAACGTTGAATGCGAGGTCTGTGGAGACAAATTCTTCGGGCCTTACGATGTGAAATTACATATGTTAAAACACAATGGAGATAAAAAATTCGTTTGCACAGTTTGCGGCAAGAAATTTTCTAAGAAAAGCAACTTGAACTCACATTTCGTTATACATACAGGAAGCAAGAAGTATTCGtgtaaaatttgcaataaagACTTTGCCCATCGTCCAAATCTGAGAATTCATTTCAGGACTAGACATCCTGATTATGAGACTAGGTTTGTGGTAGAAGAGAGCACCGGAATTATTGACGAAGTTGATGATTCGGAAATAGTGCAGATGGATTTTGTTAGGGATGAACTCGAAGGAGCGGAGTTGACCGGACAATATATTGATTAG
Protein Sequence
MHRDANRRRRHNLQILFNNTTVIPFKGRGRFKCFYCGTAIVDYQEFRQHTKTHNPCSINDRAIKLVKTDEAEVRVDVSTVICEICNESKANFEDLIAHLIDEHNVMYDTEIKLLIMKYKLEDFKCVLCDQKCNTLIALLTHVSKSHDTSKLLSCSECRQKFKKKGELDAHTRAYHKKEYNCTKCSLSFSSYFELQNHKSNSHIAMCNICFRPFATAKKRLQHLKLEHGNDDLRCGFCNKIVSTKIGFLKHASKCIEMEKKHSRQDLEDFIGFNIDVLNTERVIKKASVKTIRNNIACLLNNSTAVPFKFFMNRFRCFYCPKDFNDCDGLKEHTKIEHPYCDTKFKCMLMRNREYGKIKVDVSSLFCKLCFEPMKDLDYLVDHLISEHKSNFDKTVDSNIQGFSLIRDSYLCPFCGEVFRYFSNVLKHISQTHSNNNAVCMHCGATFRNLPNLRAHIYKHHRQTKPSKYRCAKCKLHFSCKKDYQTHFGKVHGNKMFDCPTCQEKFSSAHTKDRHMINVHQLGHKCSHCGKLFPRNSQMVDHVRRTHLKEKNVQCQICRELFFDVHVLRLHMVTHCGERKFQCDVCSKKFLWKKNLIDVIGAAQTQSFNRRRNLQILFNNTTLCPFKWRGKYLCFYCGEDMPNYEELKKHTKGHGPCTDRDRAIRLVKAADAEVKIDVSDITCEICKECFVSFDEIVGHLKHKHELPYDTGVKLSLVIYRLIDLQCLFCEEKFNYFNKLIKHVNNMHPSESFECCKCLQMFNKKRDLDAHTRMHHKKDYRCLKCSVTFASYAVFKKHNLNSHISTCNVCFKNFASLKKRLKHMKQEHANDMLQCGFCSKTMSTKQSFLRHATKCNLRINSSEKVIVDDEDRKPSVIQIRNNVACVLNMSTAIPFKYFMSRFRCFYCPKDFYECTDLREHTVTEHPHCDIKLKSMKLRNRHDGCIKIDISSLSCKLCFEPIHDLEALIDHLIFNHKANYDKSIDCNMQPYRLIKDNFSCPLCGEVYRYFSSLLRHIGNFHTDNKYICVYCGKSLRNVSNLRAHVSSKHNTAVHKCSKCDMEFNSNSHLQTHLGSAHGMKVIQCSECQEKFISNYRMQRHMVNVHRSGHKCTFCGKLFTRNSLMKNFFADEIAHSKYENYTSERRRKNLKILFNNTSIIPFKWRGKYLCFYCGKNYADYPEFKKHTKSHGLCTTKDYSLKLVKGSHNEIKIDISDMNCEICNEPFTSLDEIISHLIGKHSLEYDKSIVIAYQEYLLADSLCQFCGEHFEYFGYLITHINTIHPQNCFMCDDCGLTFNKKRDLAYHIRQNHRRGGYPCDECSDVFESQGLMRKHKNTFHFRKCKSCHSRFASFTLLQKHIKLEHSVTAIKKCPHCAKECHSRQGLMQHLRTCKVKMIVKRDKPTTFPSRMLLMPRKTQNISQIRQNIVCVLNMSTVIPFKFFAKFSCFHCSKKFTEFEELKEHTALEHPVCDMKSKCIIKCKGERTCVKIDVTSLACKICCQSMEDLDALIDHLISKHKANYDKSLTECFEPFKLVKDNIPCPHCSNMFRYFATLIRHINAEHCNSKRICDFCGRCFKNAANLNVHIIYTHTGSCECDICGLKFKNQWCLGRHKAKSHDAKDFKCPKCPEQFQSQYHKQKHLIQVHDIGHKCSYCGRMFTRNSFMKDHIRRTHLKEKNVPCSVCNEKFFDNYLLKLHMVKHDGERKFSCSVCSKTFLRRSNLSSHMDMHKKYGHVQEHKREDSVKKKSMFIKGTNFFAGAKYNSVEDKYKKRELARKLLLKRRNVEYVLQYGNVTPFMWYKGRYRCFYCAEPMKDPVLLREHTAKVHQFANLELVVHDRTKNNRNRDAAVKIDVTDISCKLCPQAVNSLEQLIHHLIIAHDAEYDVSVPNCLLPFKLDRDHPSCPICNLQFVFFEYLLRHANKHHLAHDYICDVCGTSFQGENHLKMHNRYYHREGGYTCEHCGLSLATLSKKTLHEKNVHMINLSTCPHCPETFKSPYFKKLHLANVHGVEELKIKCPYCPKVYPQESIMSRHMRRVHLREKNVECEVCGDKFFGPYDVKLHMLKHNGDKKFVCTVCGKKFSKKSNLNSHFVIHTGSKKYSCKICNKDFAHRPNLRIHFRTRHPDYETRFVVEESTGIIDEVDDSEIVQMDFVRDELEGAELTGQYID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-