Basic Information

Gene Symbol
-
Assembly
GCA_900490015.1
Location
UELV01002304.1:1-9905[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.35 47 5.6 0.4 1 23 760 783 760 783 0.83
2 9 8.9e-05 0.012 16.9 0.4 2 23 835 856 834 856 0.97
3 9 0.38 50 5.5 2.5 3 21 1029 1047 1027 1048 0.94
4 9 1.1 1.5e+02 4.0 0.4 3 23 1069 1089 1067 1089 0.96
5 9 0.053 7.1 8.2 0.4 1 20 1167 1186 1167 1188 0.93
6 9 0.52 69 5.1 1.7 2 19 1213 1230 1212 1231 0.95
7 9 0.37 50 5.5 0.2 1 23 1256 1279 1256 1279 0.97
8 9 0.0031 0.41 12.1 0.3 1 23 1331 1353 1331 1353 0.97
9 9 0.015 2 9.9 0.7 3 23 1673 1693 1671 1693 0.94

Sequence Information

Coding Sequence
GTGGCAGAAGAAGTTCATCCAATAAAAAGGTCAAAAGTAACATTTTCAGCAGTATCCAAATCACCTGATGTAAAAAAGTCAACATCGGTTCCCACATCTCCAGCAAAGACCATCTGTTCATTATTCTCCTTGGACTGTACAAAGCACACTCATCATCATTCTCACAATGGCGAGTGCCCAATATCCCTGAAAGTAAAGCAAGATTCTCATGTTCTATTGACCAGACTAGAGCAGTTAAAGGATCCGCTAGTCGTCGAGTATCTTAAAAAGACTGATCTAACTTACAAAATCAAAAACGATTTGTTTTCGCCCCAAAATGATATGATCAACAGTGATAATGCAAAAACGAGTTTAGACAGTCAGAAGCAACAAATTCCTTGTGCTACTCAAGAGGAGGAACAAACTGCCAAAGATAATTGCCCAAGTTTAAGCATACCACTGATCACCTCAGAAATAAATTCTAGTGAAGTCCAGGCAGAAGCAACGGCAGCTCCAAGTGACGTCACTCGACAAACAATAGTCGAgagcaataaaaataatcagtcTCCATCGCGATCTGTGACAAGAATGAGGCACAGGACCCTGAGTAGAACCTCTACTATAGAGTCACTAAATGTTAGTACTAAGCGAAAGAAACCCCCTGTTAGTTATGCGGAAGAATCTAGTGACTCGGAATTATCTCAATCCTCTTCATTTTTTTCGATGCAACTAAGGACACGATCACAgaGTCGCGGACCGACGCTGCGCGAGCGAAGTAAACGTGAAAATTATCTCGTACATGACCAGGATGAGAACGATATGGAGGTGGAGGAATTTACACGAATTGGTAAAAGAACTAAACTGCAGAACTACGAAGAGAATGATTTGAATCAGGCTGACACGGATAAGGGAGAACCGGCCATTTGTAAGAGAACAAGATCTAAAAGTCAGTGCGGAGGAGCTATTGATACCATTATGGAAAATATTCGTCCTCGGTGTAAGAGCGTTCTTGAGAGGAAATTAGAAGAGACTTCAAAAGTGCAATCTAAAGTGAAAACACCAAGTGAAAGCTTATCGAATAAGCTAAATGAACAGTCCCTTGAAACTCAAGATGAACTAGTCATACAAGCTCAAGCTGACGAAGCAATTCTTGATAAGGAAATGGATACGCTTTCACATACTTGTACTCCACGGATCAAGTCCCACAGCAAAAATGACCATCAGACTGTAAAAAGTCCGAGTTTCAATCAGCAAGAAACTGAATACAATAACAACAGCTGTGTTAATGATGAGCAGTCGCAGATCAGTGGTCTGCGAACGCCTACCTTAAGCATTCGAGCTTCTAGTGAGCGGATGCTCGCCACACCCAAGACcgttaataaaaatgatagtaCCCCTCACTCCACTAGAAGACCGTACAGTAGAGCTTCTAAAATGGATGAATCTTTTACACCTAAAAAAGCTCCGGCTACTCCAATGCAAAGTGAGAGAGATGGAAGTTCGGTGTGCAGTCGCAGTAGCAGTCGCTCTGATACCCCTTTCAAATATTCCAAACGGCCTGGAATTAAGAaaaatctacttattaactTGAATAAGCATGGATCAAGTTCAGAAATTTCAAGCAAGCCGACAACTAATGACATATCTCTAAAGAATCTcaaggTTCAGCTTATAAAATTAGAAGCGGTTTGCGGCACTTTTGAAGATTATTCAGCTAGTGAGATTGAGTTGTTGactgaaaaatatattgatcTGTTGATGAATTCGAATTTCTCTTGCGATACCTGGCGCAAGCCTATCAGTTATGATCGATCTAGAACATTAACAGATACACACGCTGAGGAAATCGACAATTCCGACTACATTACAGACGTCGAAATGCCGGAAGAGGAGATTGACAGCAAAACTAATGTGCTGCTTCTTAAAATACAAGATCCCATTGCTTTTGTAAGTGTAGAACTAGATCTTGAAGAAAATACAGTTGATGAAATACCAAAGGTGGGAAGTCCCAAAAAGTCTGATCAGCAACAACAAGAGCCACAAAATACTTCATTAACGTCTTTAGATACTGCGATTGCAATGCTTGTTGAAACAGAACGACCCCCGGAAAGAAACTTTGGGGCTGTTAATATTTCAGAAGCCCTGCATGTGCCAGTGAGTAAGGAAAAAGATAAAGTACAGACTATCGAACcaagtgaaaaaaatgttagtaGTGATAACCAGGAACGATTAGAAACAATCGATTGCCAAGTGCCTTCTATAGATCCAAACACAATTTTGGTAAATGGCACAACCATGTTTGCCTGTCCCTTATGCAACAAAATATTCGTTGAGTTACATATTTTTAATCGCCATGCGGTAAAAGACCATCAAAATAGGAGCAAACCTACTGCTAGTACTTCATCTGCATCTACCACATCGAAGTCCTCTGAAAAATCAGCGAACGAAACTCCCAGTGAATCGTTCGCGAAGAAATCTTCATCTGtgaaaagtaagaaaaaatacaaatgtTCAGACAGTTTGAAATGCACAATTTGCTCGGTGACATTCGACACAAAAGAACTACTCTTTGATCACATAATGACCCACAATGAGCAAGAGCTGCAAGAAGCTTATAAAACAGCCAAACTGCAACAGCAAAAGAATCAACAGCAACGGGAGGCAGACGACAGTATGTCGGAAGAATCAGATAAAGAACCACACCTAGACGTGAGCAGTACGCTCGGTGAAGgcaagagcaagaaaaaaaagaaaaagaacaaagatAAGTCAAAGAGAACTAAGAATACGGATAGTAATATACGAAACAGTAGGTCATCGATAGAAGGCGAGGAAATAAGTTCTGACGATCCGTTACAAATTGCCGTTATTAAAAAGGTACCTAGTACATCTGGTACACCTGCTGAACAAACACAAAAAGAATTAATGAACAGAGTTGATAAGCAATTGATGTTTTTGCAGGGAGCGGATTTTGCAAGGCACGATGCTTATGCTACAATTGAACGCATACAGCCCAACAGTACTAACAGTAAACCTATAACTATTTGCCCTTGTCATGCATATGAGACAACTAATCAGGACCTTCAAATCGAGATGCTTCTTTTTTGCAAAACGTGTAATGTTCTCTTCCGGCGTCGTGATTGTTTTGAAGTCCACTACCGTAATAGTCCGGAATGTCGGCGTAAGCGTACTAATAACGAAATAACAAAAGTGCCCAAACTTTTCTGTAGTGGATGCCCTTGTGTTCTCGATTCACTTATGGACATGCGGTCGCATCTCGAGATGCACGCAAGACAGAATTGTCATGGTACAGTAacgtttatttgtaatatttgtaagGTAGCCTTCTTTGGAGTGGGCGGAATCTTTTATTCGCATTGGTTCAGTCACACGAAGTCGCCGAATTTTGTCGCTAGTCGCTATTCATTCCCAAAGCTGTCAGTAGTATCGGTGCTGGAAGATTCGAATGTTTCGATGACGACCAGCAAGAGTCAAGAGGGATTCTTTTATATTGCTGAACACGTTTGCCGACAGTGCAGATTACCATTTAGTTCTGAGCCAGAGCTTCAAAAGCATAAGCTCAACCCCTGTCAATCTCAGCAACCGGTACCCCGCTTGGAGATCCCGGAGAGCAATCGTCTTCAAATGATAAAGCTCATCTGCGATCTTTGTAAAAAGTACTACGTGAGCAAAGAAAATTTCGACCGCCATTGTAGTGAACGCAATCACCTTAAGACTCCAATCACTAAATTCTCTCGATTGCCTATTAATGCTAACGAGCAAGCTTTTGTATGTAGCCTGTGTCGCGCTATAAGCAAGTCTCTTGATGACATGAAGGAACATTGGAAACGAATCCACAGTCCTATAATGGAACTTTACACCTGCAAAACATGTAATGTTGTGCCTTCCAATGATGTTACGAATTACACTTACGAAAAATTCGAGCGTCACTGTCGTTTAGCACATAAGAGCGAAGTTATCACATGTTTGGTTTATTTCGTAACTGCCAGATATGTTTGTAACATCTGCAAGTTTGGTTTTGAGACTGAGGAGTCGATGAAGGAACATCAAGTTATGCACGAAAAGAGGTCGTGTCAAGAGACTTCTGGACCACCACAATTACTACCTGTATCAACAGCAGGTCTGCCAGCTGATCCTCAAACAGTTACACTCTGGGTAGCTGATAAACCAACGACTCCGGATGGCGGGAGACAGGTGCATCCTGTTTATGTGCACTATCCAGGAGTCAATAAGAATGTCACTTATCCAGCGTCAGGACCAATAgctcCTACACCGCAAGCACATCAGCAGCAAGTACAAATTCGAAGTCAAGTTCAAGGATCTGGTGCCGCGGTCAACATTATTTCCAACGACTCCGCGGACAATAATACACCACTAACACCAGCGACCATGAACAATATGTTACGAAACATTCTGAATCAATCCACACTCCATCAGCCGGAACAGCAGCAAAATTCTTCCAAAATCCCGAGCGTTGAGACAATAGTGCTGGATTCAAGGTCAAACAGCCCTGTTACAGATACCGCTGTGACTCCAGTTTCGACTAATAGTCTTCCTGCGAGTAATGAAACTACTACAAATATTGACAATCCAGCCGGTACGTCCAGAAAATCTTACATGACCATGGTGAATCCGGACTTTGAGTCGATGCTTGGAACAAACACTACCAACTCCGCGGAGAATAGGAGCGGTAGTCTACCTCTGGAGAAGCAGAAATCAAACTCTGCCAATGTCGATAAATCTGCTAGTGTAGATTCCTCGGCACCGGAACCATTTGAGGTCGTTCTCGTGACTGATGATTTAAGTGAGAACTCTAATGGTGAAACCCCAAACGAGAAAGACAAAAATCCATCTTCAGACAAAACGACAGAGAGTACAGAAAATGTGGCGAATCAACAagagcagcagaagcagcagaagcagcagaagcagcagcagacgTCTGGAAACAATGAGATCAAGTCATTTCTACGTGTTCGTTCAATAGCTGAGCTGCAGAGTATGAAAATCCATTTGTGCTCGATGTGTGGACTGAGTTTCGATTCCCCTCAGGCTTTCGAAGAGCATTCGAAGCAGCACGACTTAACATCGGTAGCTCCACAAATTGCAGGCGACGTTGGACGAACGACCCCAGTTCAGATGATCTCTCCGATGGTTACACAAACCAACAAGGAAACAATAAGCGATCCGCAAAGTATAATTATTGCTCAGATGAGACAGAAAATGTCTGTGATAACGTCTAATGGGCAGAATTCGCCGAAAGATCTGAATACGAGAATGAGCTCACCAGCTCTTTCCAATAACCAacagcaccaacagcagcagccttACTGGTTTGCATCCTGTAACGGTATGGAGAATACGACCCAACcgaatataaattacaatagcTATAGCGTCAATCGTCAGacgcagaagcagcagcagaatcAGCCAAATATTTTTCGACGAAGTTCTAATAACGTTGGTAGTACAATGAACAATAGTTACTCTTCACGTGGCCCGCCACCCCTGTATCCTGGAACTTCAAATTCAGGAATATCCAGTCGACCCACCGCTATACAGTTACCAGAAAGAAACATTACAGCCAACAGTGCACCAATGACTAAGCGGCCATCTGGTGCAGCAACGAGGATTCCCCAACAAAATTTCGACGAATCTCGTGAACATCACCAAGCA
Protein Sequence
VAEEVHPIKRSKVTFSAVSKSPDVKKSTSVPTSPAKTICSLFSLDCTKHTHHHSHNGECPISLKVKQDSHVLLTRLEQLKDPLVVEYLKKTDLTYKIKNDLFSPQNDMINSDNAKTSLDSQKQQIPCATQEEEQTAKDNCPSLSIPLITSEINSSEVQAEATAAPSDVTRQTIVESNKNNQSPSRSVTRMRHRTLSRTSTIESLNVSTKRKKPPVSYAEESSDSELSQSSSFFSMQLRTRSQSRGPTLRERSKRENYLVHDQDENDMEVEEFTRIGKRTKLQNYEENDLNQADTDKGEPAICKRTRSKSQCGGAIDTIMENIRPRCKSVLERKLEETSKVQSKVKTPSESLSNKLNEQSLETQDELVIQAQADEAILDKEMDTLSHTCTPRIKSHSKNDHQTVKSPSFNQQETEYNNNSCVNDEQSQISGLRTPTLSIRASSERMLATPKTVNKNDSTPHSTRRPYSRASKMDESFTPKKAPATPMQSERDGSSVCSRSSSRSDTPFKYSKRPGIKKNLLINLNKHGSSSEISSKPTTNDISLKNLKVQLIKLEAVCGTFEDYSASEIELLTEKYIDLLMNSNFSCDTWRKPISYDRSRTLTDTHAEEIDNSDYITDVEMPEEEIDSKTNVLLLKIQDPIAFVSVELDLEENTVDEIPKVGSPKKSDQQQQEPQNTSLTSLDTAIAMLVETERPPERNFGAVNISEALHVPVSKEKDKVQTIEPSEKNVSSDNQERLETIDCQVPSIDPNTILVNGTTMFACPLCNKIFVELHIFNRHAVKDHQNRSKPTASTSSASTTSKSSEKSANETPSESFAKKSSSVKSKKKYKCSDSLKCTICSVTFDTKELLFDHIMTHNEQELQEAYKTAKLQQQKNQQQREADDSMSEESDKEPHLDVSSTLGEGKSKKKKKKNKDKSKRTKNTDSNIRNSRSSIEGEEISSDDPLQIAVIKKVPSTSGTPAEQTQKELMNRVDKQLMFLQGADFARHDAYATIERIQPNSTNSKPITICPCHAYETTNQDLQIEMLLFCKTCNVLFRRRDCFEVHYRNSPECRRKRTNNEITKVPKLFCSGCPCVLDSLMDMRSHLEMHARQNCHGTVTFICNICKVAFFGVGGIFYSHWFSHTKSPNFVASRYSFPKLSVVSVLEDSNVSMTTSKSQEGFFYIAEHVCRQCRLPFSSEPELQKHKLNPCQSQQPVPRLEIPESNRLQMIKLICDLCKKYYVSKENFDRHCSERNHLKTPITKFSRLPINANEQAFVCSLCRAISKSLDDMKEHWKRIHSPIMELYTCKTCNVVPSNDVTNYTYEKFERHCRLAHKSEVITCLVYFVTARYVCNICKFGFETEESMKEHQVMHEKRSCQETSGPPQLLPVSTAGLPADPQTVTLWVADKPTTPDGGRQVHPVYVHYPGVNKNVTYPASGPIAPTPQAHQQQVQIRSQVQGSGAAVNIISNDSADNNTPLTPATMNNMLRNILNQSTLHQPEQQQNSSKIPSVETIVLDSRSNSPVTDTAVTPVSTNSLPASNETTTNIDNPAGTSRKSYMTMVNPDFESMLGTNTTNSAENRSGSLPLEKQKSNSANVDKSASVDSSAPEPFEVVLVTDDLSENSNGETPNEKDKNPSSDKTTESTENVANQQEQQKQQKQQKQQQTSGNNEIKSFLRVRSIAELQSMKIHLCSMCGLSFDSPQAFEEHSKQHDLTSVAPQIAGDVGRTTPVQMISPMVTQTNKETISDPQSIIIAQMRQKMSVITSNGQNSPKDLNTRMSSPALSNNQQHQQQQPYWFASCNGMENTTQPNINYNSYSVNRQTQKQQQNQPNIFRRSSNNVGSTMNNSYSSRGPPPLYPGTSNSGISSRPTAIQLPERNITANSAPMTKRPSGAATRIPQQNFDESREHHQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00969125;
90% Identity
iTF_00969125;
80% Identity
-