Basic Information

Gene Symbol
-
Assembly
GCA_900490015.1
Location
UELV01175819.1:16092-18887[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 3.8 5.1e+02 2.4 0.9 1 15 181 195 181 204 0.64
2 16 0.036 4.8 8.7 3.2 2 23 281 303 281 303 0.97
3 16 0.016 2.1 9.9 1.2 2 23 330 352 329 352 0.93
4 16 1.7 2.2e+02 3.5 0.3 2 23 452 474 452 474 0.90
5 16 2.8 3.7e+02 2.8 0.8 1 23 503 526 503 526 0.86
6 16 1.8 2.4e+02 3.4 8.7 1 23 541 564 541 564 0.97
7 16 3.3 4.3e+02 2.6 1.3 1 23 574 597 574 597 0.93
8 16 9.1 1.2e+03 1.2 3.7 1 23 614 636 614 636 0.93
9 16 0.0098 1.3 10.5 1.4 1 23 649 672 649 672 0.97
10 16 0.014 1.9 10.0 1.5 3 23 693 714 691 714 0.95
11 16 6e-06 0.0008 20.6 1.3 1 23 720 743 720 743 0.95
12 16 0.00047 0.063 14.7 1.2 3 23 750 771 748 771 0.93
13 16 0.0036 0.47 11.9 0.3 1 23 776 799 776 799 0.95
14 16 1.5e-07 2e-05 25.6 0.4 3 23 807 827 806 827 0.98
15 16 3.2e-05 0.0042 18.4 0.4 1 23 833 855 833 855 0.98
16 16 3.4e-07 4.5e-05 24.6 0.7 1 23 861 883 861 883 0.98

Sequence Information

Coding Sequence
ATGTCAAAAGCATGCGAGTCTCGTCCTACAACCCAATTTTTCAGCTCCACGCTGCATCGACATACGCATAGTACCAGTCCAGTGCTatCGTCGTCGgcgaacaacaacaacagccgTCGCTTCGTCTTCCAAAAGAAGCTCGTCAAGATCCAACCCCTGCAAATAGACTCGCGCGGCCAGGTCGTGCGCACTGCTCAGGCGCCGCCTCTGGTGCGCGTCAAGCTCGAACCCGCGGAGCCTACGGTTGACGAGCCACAACAATACCAGGAGGTCGTCAGCTATCCAGAAGCTGTAGCCGCTGTTGCCCCCGTAATTGTGAAAAAACCCAACCAAATCATCGTCTATCTCTGCAAGCCCTGCAAGATCTACTTTCCGATCAAGCAGATGCTCGAGGTGCACAATGCCACAATGCaccaacaacagcagcagcagcagcagcagcagcagcagcagcagaaggagAAGAGGGAGACGAGTCGGTGCCGCGTCGAGGGCGACAAGATCTTCTACGCGGGCTATCACAAGGTGAAGAGCGGCGCCTACGTGTGCAACTACTGCTCGTTCAAGTCGTTCGTGCGCACGACAGTCTCGTCACACGCGGCCCGCAAGCACAGTTCCCTCATACAGATGAACAGTAAGCCGACTACGAGTAGCGAGGAGGCCGAGGAGAGTAAAGACCAACACGCCGAAGTgtgcagcggtggcggcggcggcaccgaGCTCAAGACCGAGGTGGCCGACATAGAGGACGAGGATTTCTGGCCGATGGACGTGATCGAGGAGGTCGAGGACGACCCGGGACCCGAGCCTCCCATCCAAAGAGTCGTAGAGCCGACTCGTACCTGTCCCTATTGTCCTTTCGAGACGACCAAGTCCTCGACCTTTCACTCGCATGTTAAGCGCAGACATCGCGACAATTGGCTCAAGTCGGTCGCGCAGAAGGTCGCTGCTCTACAGCCCGGTGTTCAAGATGTTAAAGCTGTGATGAAATGCGACGAGTGTCCTTACAGGTGCTCGAAGCTCGAGGACATGCAGATGCACATGATCGACAAGCACGGTTACGAGACTCTGGAGGTGGACATGCTGAACGAGGAGTAcgggaaagaagaagaagtggaTGAATCAgcaggagtagcagcagcagcagcagcagtcgaggAGTACGAGGTTGACAACGTGGTGGAGGGGGAGGAGGGCGAGAGCATAGTGTATACCCATGGCGAGAGCATCGAGATCGTGGACTCAATGGATGCACCAGCTCTCGAGGAGGAAGTAATAGAGGAGGAGGTGGCGATGGAGGAACAGGAGGAGGCGgcgaccacgacgacgacgactcctGCGCGAAAGTCACGCAAGTGTCCCTACTGTCCGTTCGAGTCGTGGATCAACTCGACCCTCAATTCCCACATAACGCGTCGTCACAAGAGCCAGCCGACGCGTCGTCGTTGCAGGGATGACGATGAGCTGAGCGGACGCAGACAGCCTAATGCCCAGATGTACACCGGCTACGCCTGCCACTATTGCACCTTCGTCGCAGCGACCGTCGCCAGTATCAAGAACCACTCGACTAGGCAGCACCAGGGCCTGAAGCAGCCGATCAAGGAGGTGCCCGTCAATGAGTACGACTGCCACCTCTGCGAGCACAAGTCCAGGTATCGCAGGAACATGCAGCTCCATATCAAGAAGTGTCACACTACCCAGGCAAATGACGAGGGCATGTTCAGCTGTCACGCCTGCTCCTACGAGACGTTGTCGCGCATGGGCCTACAGAGGCACATATCGATCAAGCACAACAGCTCGAGGAAGGACATAGGCTTCAAACTGATCAAGGGCGCCTGCTACGAGTGCAACGAGTGCGAGTTCAAGTGTCTGAACAGGAAGACCATGGACTGGCACAAGAGGCAGCACGTAGCGAGGCCCAATGCCGAGGATGACGGCAACAGTTACTTCTGCAACGACTGCGACTTCTCGACCTGGACCAAGGGCCAGCTCTACATGCACATAAGGCGCAAGCACAAGGACAGCGAGGGCAATGCCAGAGAGACGGACGCGGATCAGTCGGAGCAGCTCTACGGCTGCGAGCAGTGCGACTACACGACCAAAAACAAGCACGCGATGAAGGTCCACGTGATCAGGAAACATACCACGGAGTACAATCACGAGTGCGAGATATGCGGCAAGAAGTACAAGGTCAAGGCTGACCTGACCAATCACATAAGGTTCCAGCACAGGGAGCAGCCGATCATATGCGACGTGTGCGGCAAGACCTGCCGTAACAGCAATCTCCTCTATCTGCACCAGAAGTTCGCCCATTACAAGCCCGAGTTCGAGTGTCCGATCTGTCACAGGCGTATGGTCAGCCAGGCGAATCTCGACGATCACATAGTCAAGCAGCACGAGCAGAGAGAGGACGCCATATGCGAGGAGTGCGGCAAGACGTTTACTCGACAGGCGAGGCTCAAGGTCCACATGAGGATACACACGGGTGTCAAGCCCTACACCTGCAAAGTCTGTCTAAAGGCGTTCGCGCGTAGGAACGGCCTGAGGCAGCATCTATTGATACACACGGGACAGAGGCCCTACATATGCGATATATGCGGCAAGACCTTTACCCAGAAGACGGGACTGATTAGTCACAGGAAGAGCCATCCGGGCACGCATCCGCCCCTCCCCAGGGTAACCATTGATCATGTGCTCTCGGAACTGCTCAACGAAGAGAATTGA
Protein Sequence
MSKACESRPTTQFFSSTLHRHTHSTSPVLSSSANNNNSRRFVFQKKLVKIQPLQIDSRGQVVRTAQAPPLVRVKLEPAEPTVDEPQQYQEVVSYPEAVAAVAPVIVKKPNQIIVYLCKPCKIYFPIKQMLEVHNATMHQQQQQQQQQQQQQQKEKRETSRCRVEGDKIFYAGYHKVKSGAYVCNYCSFKSFVRTTVSSHAARKHSSLIQMNSKPTTSSEEAEESKDQHAEVCSGGGGGTELKTEVADIEDEDFWPMDVIEEVEDDPGPEPPIQRVVEPTRTCPYCPFETTKSSTFHSHVKRRHRDNWLKSVAQKVAALQPGVQDVKAVMKCDECPYRCSKLEDMQMHMIDKHGYETLEVDMLNEEYGKEEEVDESAGVAAAAAAVEEYEVDNVVEGEEGESIVYTHGESIEIVDSMDAPALEEEVIEEEVAMEEQEEAATTTTTTPARKSRKCPYCPFESWINSTLNSHITRRHKSQPTRRRCRDDDELSGRRQPNAQMYTGYACHYCTFVAATVASIKNHSTRQHQGLKQPIKEVPVNEYDCHLCEHKSRYRRNMQLHIKKCHTTQANDEGMFSCHACSYETLSRMGLQRHISIKHNSSRKDIGFKLIKGACYECNECEFKCLNRKTMDWHKRQHVARPNAEDDGNSYFCNDCDFSTWTKGQLYMHIRRKHKDSEGNARETDADQSEQLYGCEQCDYTTKNKHAMKVHVIRKHTTEYNHECEICGKKYKVKADLTNHIRFQHREQPIICDVCGKTCRNSNLLYLHQKFAHYKPEFECPICHRRMVSQANLDDHIVKQHEQREDAICEECGKTFTRQARLKVHMRIHTGVKPYTCKVCLKAFARRNGLRQHLLIHTGQRPYICDICGKTFTQKTGLISHRKSHPGTHPPLPRVTIDHVLSELLNEEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00969079;
90% Identity
iTF_00969079;
80% Identity
-