Basic Information

Insect: Megastigmus dorsalis
Gene Symbol: zfh1
Assembly: GCA_900490025.1
Location: UELU01141137.1:17892-25561[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.07 8.7 7.8 0.7 2 23 109 131 109 131 0.90

2 7 3.2e-05 0.0039 18.3 0.6 2 23 153 174 152 174 0.97

3 7 7.5e-06 0.00093 20.3 7.8 1 23 183 205 183 205 0.99

4 7 1.9e-05 0.0023 19.0 1.9 1 21 211 231 211 232 0.95

5 7 0.00011 0.014 16.6 4.7 1 23 785 807 785 807 0.94

6 7 2.6e-05 0.0033 18.6 8.1 1 23 813 835 813 835 0.98

7 7 0.002 0.25 12.7 4.3 1 21 841 861 841 862 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.07	8.7	7.8	0.7	2	23	109	131	109	131	0.90
2	7	3.2e-05	0.0039	18.3	0.6	2	23	153	174	152	174	0.97
3	7	7.5e-06	0.00093	20.3	7.8	1	23	183	205	183	205	0.99
4	7	1.9e-05	0.0023	19.0	1.9	1	21	211	231	211	232	0.95
5	7	0.00011	0.014	16.6	4.7	1	23	785	807	785	807	0.94
6	7	2.6e-05	0.0033	18.6	8.1	1	23	813	835	813	835	0.98
7	7	0.002	0.25	12.7	4.3	1	21	841	861	841	862	0.96

Sequence Information

Coding Sequence: ATGCATAACGGACCTTTTCGAGGGTGCAGCGAGGACGAGGCAGGTGCCGACGCGGAAGTGGGCGGTTGCGCCGAGGGCGCAGCTAATGGTGGGAaaggcggcagcggcggcggcgtagGCGAGGGCGGCACCGAAGGAggcaccaccaccgccgccaccaccaccgccgccggcagcaccgccgccgccgccgccgccactcaCGCGaccaacagcagtagcagcacagccgccgccgccgccgccgccgcagcagcagcagccgctggCAGcacgaccagcagcagcagcagcagcagcggcaagcAGTCGACGACGTGCGAGCGTTGTCCACAGTGCGGCATCGTCTGCCGGAACTCGCGCATACTCCAGCTCCACCTCGAGGACCAGCACAAGGCGGTCGGTGCCTACAACGCCATCGACAAGCACGACCTCCAGGCGCAGTTCTCCCAAGTCTCGTGTAAGGTGTGCAGTAAAACTTTCGCAAACGTGTACAGACTACAAAGGCACATGATCAGCCACGACGAAAGCGCGGTACTCCGCAAATTCAAGTGTCCTCACTGCGAGAAGGCCTTCAAATTCAAACATCACCTTAAGGAGCACTTAAGAATACACAGCGGGGAGAAGCCCTTCCAATGCAACAACTGCGGCAAGCGATTCTCCCACTCGGGCTCCTACTCCTCGCACATGACGTCCAAGAAGTGTCTCGTGGTGAATCTGAAAAAGTCGAGACAGAGCTCCAGCGTGAATTCGGGCCTCGGCGCCCCCACCTCCGAGCGCAATCCCGCCTGCGGCGACAAGAAGCCGCTCCAGCAGCGACAGCCGGCTCCTCTTCGACGACtccagccgccgccgccgccgccacagcctcagcagcagccacagccacagccgcagccgcagccgcagccacagcaacagcagccgcaggagccacagcagcagcagcagcagcaacagcagacgCTGCAGATGAGGCGCGAGGTCGAGCTGCTCGCCGCCAACAACAACACCTTCCTGCCGATCCTGCCCAAGCTCTCGCCCTCCGACTACCGGGACATGCAGCGAGACGCAGCAGGTCTCTACGACATGCCTACGCTACTACCTCACATGATGGGCTTTGGCAGCTACTTCCTCCAGTCCGAGCACTACGACGCCCTGAGCCAGCAGAGCGAGGCGGCCCTGAGTCCCTCGACGACTGCCGCGGACTCGGAGGACGCTGTAACCGAGGGCACCGAGGGCACCGAGGGCACCGAGGGCGACAACTGCTCGCCCGCCCCGCCGCCGCCCGGACTCCTCCacctccaccaccaccacaacCACAACCACAACCACAACCACCACCAGCCCCCGGTCGAACAGTCGCAAGGCCTCGACGCCGTCAGGCGACTCCTCGAGACCGTCAATACCTCCGTCACGAAGCAGCTGCTCGAGGCCAACGTGAGGAAGCTCGCTTCCTCCCCGGCTATCGTCATCAAGCGCGAGATCGACGAGGACTATCAGGACCAGGATAGCGAGATGTCGAGCGAAATGGCGCACTACCCGGCCGATTGGTCGGCCACGGAACAGTGCGACTCGCAGAGCGAGGGCCTGGCAGCTAAGCTCGAGGAGGTGCACCACAAGGCGATACCCTCGCCCTGCCATCAGTCCGGGATTAAGCGCAAAGCCGAGAACGGACTCTCGGCCCACACATCCGAGGCGGACagcgaggacgacgacgagtcGCTGCAGAGGCAGCACCTGCACCAGGACGAGAGCGCGAGCGGGGCGGCGCGTAGAGTCAGGGCGAGGTCGCTCATCGACGACGAGCAGCTCGCCGTACTCAAGGGCTACTACGGCATCAATCCCCGACCCAAGAAGGAGGAGATCAACATGATAGCCAGCTACATCAATTTCCCTAGGCGCGTCGTCCAGGTATGGTTTCAAAATTCTCGAGCGAGGGACCGACGCGAGGCAAAGATACCAGCCCTGGTGCCGCTCTCCAGCTTGAGTAACCTCGTGTTCAATGAGCAGCCCCTCGATCTTTCCAAGAAAGACGTACTCAGGACGATATCGACGGTAAAGGATAGTAGCGATGCCTCGAGCAGGAACACTGCCTCACCCTACGGCCCAAAAGAAGATGCTGTCGTTCCAAAACTGTTGGCGAATAATAACGTCGAACCTGAGGATGTGGAGGAGTCGCCTTTAGTCATCGATGAAGAGACCACCGATTTTACCGAGGTCAAACATACACCTATGCCTGTCGAGGTCATCATTAAGGCTCATTCTCCAGTTTTACAAATCAAAAATGATGTCGAAACCAGAGTAAACACAGACCCTACACCGCATACAGAAACGGAACAAGAAGGTCTGTACTTCTGCAACCAGTGCGACAAAACATTCTCCAAGCATAGTTCTTTAGCGAGACACAAATACGAACATTCCGGGCAAAGGCCGTACAAGTGTCAGGAGTGCCCGAAAGCATTTAAGCACAAGCATCACCTGACCGAACACAAGCGACTGCATAGCGGCGAGAAGCCCTTCCAGTGTTCCAAGTGCCTCAAGCGCTTCTCTCACTCTGGCTCCTACAGCCAACACATGAACCATCGTTACTCATACTGCAAGCCTTACAGAGAATAG
Protein Sequence: MHNGPFRGCSEDEAGADAEVGGCAEGAANGGKGGSGGGVGEGGTEGGTTTAATTTAAGSTAAAAAATHATNSSSSTAAAAAAAAAAAAAGSTTSSSSSSSGKQSTTCERCPQCGIVCRNSRILQLHLEDQHKAVGAYNAIDKHDLQAQFSQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLVVNLKKSRQSSSVNSGLGAPTSERNPACGDKKPLQQRQPAPLRRLQPPPPPPQPQQQPQPQPQPQPQPQQQQPQEPQQQQQQQQQTLQMRREVELLAANNNTFLPILPKLSPSDYRDMQRDAAGLYDMPTLLPHMMGFGSYFLQSEHYDALSQQSEAALSPSTTAADSEDAVTEGTEGTEGTEGDNCSPAPPPPGLLHLHHHHNHNHNHNHHQPPVEQSQGLDAVRRLLETVNTSVTKQLLEANVRKLASSPAIVIKREIDEDYQDQDSEMSSEMAHYPADWSATEQCDSQSEGLAAKLEEVHHKAIPSPCHQSGIKRKAENGLSAHTSEADSEDDDESLQRQHLHQDESASGAARRVRARSLIDDEQLAVLKGYYGINPRPKKEEINMIASYINFPRRVVQVWFQNSRARDRREAKIPALVPLSSLSNLVFNEQPLDLSKKDVLRTISTVKDSSDASSRNTASPYGPKEDAVVPKLLANNNVEPEDVEESPLVIDEETTDFTEVKHTPMPVEVIIKAHSPVLQIKNDVETRVNTDPTPHTETEQEGLYFCNQCDKTFSKHSSLARHKYEHSGQRPYKCQECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00968688; iTF_00969939; iTF_00969459;
90% Identity: iTF_00968688;
80% Identity: iTF_00968688;