Basic Information

Insect: Megastigmus dorsalis
Gene Symbol: ZFX
Assembly: GCA_900490025.1
Location: UELU01121379.1:38800-45167[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.9 2.4e+02 3.3 0.1 3 23 22 42 21 42 0.94

2 15 3.4 4.2e+02 2.5 3.1 1 20 951 970 951 974 0.76

3 15 0.00071 0.088 14.1 2.5 2 23 1061 1083 1060 1083 0.97

4 15 0.0011 0.13 13.5 0.4 2 23 1096 1117 1096 1117 0.98

5 15 2.1e-05 0.0026 18.9 2.3 2 23 1120 1141 1119 1141 0.97

6 15 0.014 1.8 9.9 0.3 1 23 1147 1169 1147 1169 0.95

7 15 2.9e-05 0.0035 18.5 4.5 2 23 1176 1197 1175 1198 0.95

8 15 0.13 16 7.0 3.7 5 23 1211 1229 1210 1229 0.97

9 15 2.6e-05 0.0032 18.6 1.5 3 23 1236 1257 1235 1257 0.97

10 15 0.012 1.5 10.2 0.3 2 23 1273 1293 1272 1293 0.97

11 15 7.8e-05 0.0096 17.1 0.7 1 20 1299 1318 1299 1321 0.92

12 15 9.7e-05 0.012 16.8 2.7 1 23 1329 1351 1329 1351 0.99

13 15 0.0027 0.33 12.2 3.2 1 23 1357 1379 1357 1379 0.97

14 15 4.9e-06 0.00061 20.9 3.9 1 23 1385 1407 1385 1407 0.99

15 15 0.00035 0.043 15.0 7.2 1 23 1413 1435 1413 1436 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.9	2.4e+02	3.3	0.1	3	23	22	42	21	42	0.94
2	15	3.4	4.2e+02	2.5	3.1	1	20	951	970	951	974	0.76
3	15	0.00071	0.088	14.1	2.5	2	23	1061	1083	1060	1083	0.97
4	15	0.0011	0.13	13.5	0.4	2	23	1096	1117	1096	1117	0.98
5	15	2.1e-05	0.0026	18.9	2.3	2	23	1120	1141	1119	1141	0.97
6	15	0.014	1.8	9.9	0.3	1	23	1147	1169	1147	1169	0.95
7	15	2.9e-05	0.0035	18.5	4.5	2	23	1176	1197	1175	1198	0.95
8	15	0.13	16	7.0	3.7	5	23	1211	1229	1210	1229	0.97
9	15	2.6e-05	0.0032	18.6	1.5	3	23	1236	1257	1235	1257	0.97
10	15	0.012	1.5	10.2	0.3	2	23	1273	1293	1272	1293	0.97
11	15	7.8e-05	0.0096	17.1	0.7	1	20	1299	1318	1299	1321	0.92
12	15	9.7e-05	0.012	16.8	2.7	1	23	1329	1351	1329	1351	0.99
13	15	0.0027	0.33	12.2	3.2	1	23	1357	1379	1357	1379	0.97
14	15	4.9e-06	0.00061	20.9	3.9	1	23	1385	1407	1385	1407	0.99
15	15	0.00035	0.043	15.0	7.2	1	23	1413	1435	1413	1436	0.96

Sequence Information

Coding Sequence: ATGGATCTCAGTACAGCAGTGAGTGCGATGTCAGGCAGCAGCAATGGGACTGGGGCAGTTGCCTGTccagtctgcacgctgtacctacGCGAGGGTATCAGTCTGCAGAAACACTTGGACACTCACCCCAAGGAACAGGTGATCGAGGCCCTCATTCGGGCGAGtagcggcggtggtggtggcgcCTCGGCTCTCCTAAATCAAGCCTGCGCGCAGCAATCACAGCCGCCGACTCCAGTACCCACACCGGTGCCTACGCCTACGCCATCGCTGTCACTGCCAAGCCCAGGGGCaggcgtgcagcagcagcagcagcagcagccaacacCGTCGCCGAGTCCACATGTTCCTCATGCTCAATCGCCTTATCCGATTGGGCCTATATTCGAGTGCCCACCAATCAACGCCATGATTCCACCACCTCAGTTCACTTCTTTTAGCTATCAGCAGTTTGTTAATAATGGTACGATGATGATACCCGCACAATATGCGATGGCTCAAGCACAGCCCCCGCAGACCAGTCAGATGATGCAAATGCTGTACAGTCCTTATGGTATGTACCATCAGCAGCAAATTCCTACGGTTCAAATGATCTCGGCGCCTCCGATGATGCCCACCTCGACGGCTACCTTACCAACGACGCAAGAAATTATCCGGGAGGTAATACCTGGACCTGACAGTATATTACCGGATCTAGAAGAGCCTACCACGCCCGAACCAACGCATATAGAACGCGAGGAAGAACAAACCAACATTCACGTTGAACACAGAGAACAGCAGACTCAGAACAGTTGTTTACAGGAAGAACAACAACAAGTTGTTGAACAATATCACAGAGAGGATCCACCAACGTTAATCAGTAACACTTGCGGCGTTATTACTGATGATGACAAGACTGAAAGGATCCTACCTGATATTGAAGATAACGAAGAAATTGAATCTTTAATAGTGCGTGAAAGAGACAGGGTAGAAAGTGAAAAAGACACTGAAGAACAAGTGGTAGAGTTTATTGAACACATGGAAATTTCAGCCCATGAAGAAAACATTGAAAAAGAGATCGTAGAAACTATTGCGTGTAGTGATGCAGAAGTTTGTAGAGAATCACAGGACAAAACTGAAAATCATATAGAAGTCGTGTCAGAAACTATACTGCCTCACGACCTCTCCGTCGATCAAACACAAATTTCTATCCTCAACCAACCTGAAATTGAACAACAGTTAGATCGATTAAATGTACACATAGAATCGGAATTCAGTAGCGTAGAATTAACCAACAAAGAAGACATCAGAGAAAAGCCTAATGAGCTTATCCAAGATGCAGTATCCATTGAAGTCCCCGAAAAGCCCCAGGAGGAGGACGATAGTAGTGTGCCGTATCACAAGATCTCAACCGAgccaattgaatgcaaaattaTTGTCGCTCACGAAGATACAGACGTGTCCTCCGTTGCCTCCTCAGATTCCATTCATTGCAACATGGAAGTGGAGAAAATCGCCACCTCTTACAACTACAAATACTCCCAATCAGCTCCTACCTCACCAGTTGGCAAAAAGAAGTTCTATCGTTCTATCTCGCGCGCGTCACTGCGCTCTGACTTCGACTGCTCGCTAGAGAACTTTTGTCCTTATCCAGTTGGCTTCGAAGCCACAACGCTACAGGACTTCCTCAAAGACAACTACAATGACGAGGACATGGAACTTGAGGAGCCGCAACATCACTCGTATATGAAAGAAAGTAGCGACATAATAGCCGAGCATGCAAGGTCGCATACTCCCTTGTCCACGAGTATGAGCGGCGTTTCCATTCTTAAAGCGCGTCGCAGCAAAGTGCCAAGCTCACCTGTATCTGTGCGTTCTACCTCGTCCTATGGTCAGatggaagaggaggaagaagacgaTTCAGATGCAGAGAGCTGCGGTACTCTTCACTCGAACGAAAAAGATGACGAGGACGAAGAGGAGGATGACGAGGAGGTAGATCATCTCTTGATAGGCACCGCGTCGCAACAACTCCTCGAGGACGGCGTACACGAGGAGAAGGTAATCGTACATAAAGAGGAATGCAAAGCCTTGGTAGCCGCCGAGATCATGCAACAGCAGGAGCAGCCTGCAGACTTCCGATGTCAGAGCTTAATGGCTGAGCACTACTCGACTGCTCAATTCCCACTAGATCATCATACAATTACGacgcagcagcatcagcagccaCAACAGCAACAGCCATCCGAAGTGTCGATCCACCACGAACTTTATCCACTGTCAAACAGCGGAACCTCGCAAAACCTACTCAACCTATCCGAGTGCGTGGATCCTACTACTAGCACGGACTCAAAGAGCTACTGCAGTTCCAACAAGTCAATCGCGCAGAAACCGACTACAGAGCTACTCAATATCAGCGAGGATGCGCATGCGGGGCCTATGAACGTGTTCGAGTTCGACGGACTGCAAATACTCGTGCCGAGTACGTTTATCAGCGAGTCGTCGCAGAAGGCGGTGAGCGGAACGAGTCAGCAGTCGATGTCGAGCAGCGAGAACGGAGCAGGCAACGATGAAGAGGTTAAGAGCGTTAACATGCGAGCCGATGAGACCATGCCACCGCGTGGAGAGCTGTCGGAGCAAGAGAGCAATGGCTGTACCGAGCAGTCGGCTTGGCAGATGTACATGGGACAAGATTCTTCGCGTATGTCGACGTCCTACGACCTGATGGCACGAGAGAGTTGGGAAGAGTCCGAAGGCTCGGACCACGACGACAACAACGGTGGTCCTCTTCTTGACAGCCGTTCCCTCGCCACTCATTTCACATCCAGCCTTTTTCTCGACCGCGACCGCAAGACACCCACTCGGCGAATTTTTAAATGTTCACACTGTTCGGAAGTGTTCGAATGTCCGAAAGAGCGTCGCGTCCACAGCACAATGGTACACAAAGAAGCCGGTCCTTCTAGCTGCAGTAACGACAACATAGATCAATCTGAGCTTAAGGACATAAAACTTCTCGACGGTCGAGCCAACGTCTTCGACGAGATCTTCGCACCAAGCGGTCTACATGTTCAGCCGACTTATCACCATCACCATCAACAACCACTCCTCCACCAACTGCAGCCGCCTCAGCATTCGAGCTCCGACAAAGTAGAGACTGATCCTAAGATCGACTCCCTACATCTGTCAGCTACAGCAGAGGTCACTTGTACCGTCTGCAGTCAGCGTTTCAGTAGTGAAAAGTCCTTGCAGCTCCATCATAGGCGTATACATGTAACCGAGCCCGTAAAGCGCATTCGCGAGAACGCCAAGTGCCAGATATGCAACGAGGAGTTCACCTCCGTTGCGAGCTTCAATCTCCATCTCAAAATACATCCACTCGAGTGTGGGCAGTGTGGCAAATACTTCTACCGTAAGCAGAACTTTAAGTTACATATGAAACGTCACTTGGGGATAAAACCATTCCCCTGTACCGTGTGCGACAAGGCTTTCCTTACAAAACAAAAGCTCGATGAACACACAAACGGTCACACAGGTAATGCTCCAGTAAAGTGTAACCTGTGCAACGAGACCTTCCGTCGCTACTCGAATCTCACGCAGCACAAGAATCGTCATCATTTGAACATTAAAAAGAAGCTGAAAGATTACATATGTCACTGCGGCGAAGTATTCCACACGAAGAAAAAACTTGCTTGGCACAAGGAAACGCACGACGAGAAGCCCAAGGCGTGCACCTATTGCAACGAGCGCTTCATACACATGGCGAGCTTGACCAGACACATGAGACGCGCTCACAATAGAAGATTCGTACCCGATGCGcaaagagagaacgagaacgTTGAATGCCCGATATGTAAGTGCATTTATCTGAGATCGTCGTTGGCTGTGCACATGCGAGTGCACAATGGTGAAAGGCCCTACGAGTGCCAGGTCTGTTCCAAGGCCTTCAGCACCAAGTGGAACCTACAGCTACATAAATGGACACACGCAGCTCGTAGCTCGAAACCCTTCAAGTGCAATCAGTGCAGCGCAGCGTTTTACCGACACAGCGACTACACAGCCCATATGAACTCACACAGGAACGTCAGGCCGTACACATGCAACTATTGCGGGGCTCAGTTCATCAGGAAATACAACTGTTTGCGGCACGTCAAGGAACACGAAGAGAACAAGGCGTACACTTGTGATGTGTGCAACAAGACCTTCCACAGGTCGTATTATCTAAAGGAGCATTTAAGAGTACACTCAGGCGCGAGACCTTACACTTGTCACATTTGCGGCAAGTCCAGCAGCACAAAGTCCAATCATAATAAGCACGTCAGAATTCACCACGCGCGCGAGCCTGTAAATACAGAGAATTAA
Protein Sequence: MDLSTAVSAMSGSSNGTGAVACPVCTLYLREGISLQKHLDTHPKEQVIEALIRASSGGGGGASALLNQACAQQSQPPTPVPTPVPTPTPSLSLPSPGAGVQQQQQQQPTPSPSPHVPHAQSPYPIGPIFECPPINAMIPPPQFTSFSYQQFVNNGTMMIPAQYAMAQAQPPQTSQMMQMLYSPYGMYHQQQIPTVQMISAPPMMPTSTATLPTTQEIIREVIPGPDSILPDLEEPTTPEPTHIEREEEQTNIHVEHREQQTQNSCLQEEQQQVVEQYHREDPPTLISNTCGVITDDDKTERILPDIEDNEEIESLIVRERDRVESEKDTEEQVVEFIEHMEISAHEENIEKEIVETIACSDAEVCRESQDKTENHIEVVSETILPHDLSVDQTQISILNQPEIEQQLDRLNVHIESEFSSVELTNKEDIREKPNELIQDAVSIEVPEKPQEEDDSSVPYHKISTEPIECKIIVAHEDTDVSSVASSDSIHCNMEVEKIATSYNYKYSQSAPTSPVGKKKFYRSISRASLRSDFDCSLENFCPYPVGFEATTLQDFLKDNYNDEDMELEEPQHHSYMKESSDIIAEHARSHTPLSTSMSGVSILKARRSKVPSSPVSVRSTSSYGQMEEEEEDDSDAESCGTLHSNEKDDEDEEEDDEEVDHLLIGTASQQLLEDGVHEEKVIVHKEECKALVAAEIMQQQEQPADFRCQSLMAEHYSTAQFPLDHHTITTQQHQQPQQQQPSEVSIHHELYPLSNSGTSQNLLNLSECVDPTTSTDSKSYCSSNKSIAQKPTTELLNISEDAHAGPMNVFEFDGLQILVPSTFISESSQKAVSGTSQQSMSSSENGAGNDEEVKSVNMRADETMPPRGELSEQESNGCTEQSAWQMYMGQDSSRMSTSYDLMARESWEESEGSDHDDNNGGPLLDSRSLATHFTSSLFLDRDRKTPTRRIFKCSHCSEVFECPKERRVHSTMVHKEAGPSSCSNDNIDQSELKDIKLLDGRANVFDEIFAPSGLHVQPTYHHHHQQPLLHQLQPPQHSSSDKVETDPKIDSLHLSATAEVTCTVCSQRFSSEKSLQLHHRRIHVTEPVKRIRENAKCQICNEEFTSVASFNLHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSSKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00969844;
90% Identity: iTF_00969844;
80% Identity: -