Basic Information

Gene Symbol
-
Assembly
GCA_936440415.1
Location
CAKZFH010000187.1:478393-484808[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.16 12 6.7 4.0 2 19 219 236 218 241 0.89
2 12 1.5 1.2e+02 3.6 0.2 6 23 251 268 249 268 0.88
3 12 9.2e-05 0.0071 16.8 1.5 1 23 301 324 301 324 0.95
4 12 2.3 1.8e+02 3.0 0.6 5 23 333 351 332 351 0.93
5 12 0.0037 0.28 11.8 0.4 2 23 358 379 357 379 0.97
6 12 0.00036 0.028 15.0 2.7 1 23 387 409 387 409 0.98
7 12 0.0012 0.093 13.3 1.6 1 23 418 441 418 441 0.97
8 12 0.00017 0.013 16.0 0.2 1 23 447 469 447 469 0.97
9 12 2.7e-07 2.1e-05 24.8 2.3 1 23 475 497 475 497 0.98
10 12 0.00031 0.024 15.2 1.0 1 23 502 524 502 524 0.98
11 12 2.3e-06 0.00017 21.9 4.2 1 23 530 552 530 552 0.97
12 12 0.00013 0.01 16.3 2.7 2 23 559 581 558 581 0.95

Sequence Information

Coding Sequence
ATGGCTGTAGATATTAATAATATGAAGGAACTGTGCAGGCTATGTGCACAAAACGATGTTTTTTCCAAAGATTTGCTGGAGGAGAGTAATAAAAATATCTTAAACCTCGTACAAAAATATATTAAAATCGCTATACAAGATCAAAATTATCTGCCTACAAAAATTTGTTTAAATTGTGAAGAAAAAATAGTTTGTTTTGAAATGTTTAAACTTGAATGTTGTAAAGTGCAAGAAACATTTAAAAAAATATGTGAAGATAGCCTGTCTTCTATTGTGAAACTAGAAAACCCTATTACAGTTTTTGGGACTCCAATAAAATCTGAGGTTAAAAAGGAAGCAGAAAGAGATATGATGGACGTAACAGATGTTACCGATGAAGCAGATGATGTAACAGATGATGTAACAGAAGATTTAGTATGTGCTTTAACAAATAATGATGCATCTTTGACTGTGATTGATGAATATCCTGAAAATTCAGAAATTCCCTTAAGTGACCACCATGAAGATATTGAGGCTGATGATGAATATCTTGAAAATTTATCTATAGCATCATTAAAAAAGATCAAAAGGAGAGAAGTGACAGATGAAGAGATAGAAGCATTTAATGAAGCTCTTATGAAGACAAACTTAAAACTGAAAGATGTGATAAAATTAAATTGCGTTTTTTGTGGAGAAAAATTTAAAGCATGGAAAAGTCTACGTCATCACTGTGCGAAGCGACACAAAGCCAGACCATATGTTATTTGTCTTTGTGGTTATTTGGTGCGATCTCAGAGTACTCTCTACAAGCATGTGGGAGATCATAGGCGAGAAGGTCGAAAACTGCGAAAAGAGAGTGGACAAGATGTTGAAAAGAAGAAAAAAAAATATGCTAACCTGCAAATTAAGGATTTTGTACGGTTCAATTGTGCTACGTGTGACAAGGCATGTTCTAGTTGGTACAGTCTGCAGACTCACACAGAAAGAGTACATAAACTCGCTCCAATTTTATCATGCGTGTGTGGACTCATTATCAAGTCCAAATCTGTTCTGTATAAACATATACATGACCACAAAAATCCTAATATCCTAAGATGCGATAAATGCCCCAAGATCGCTAAAACTGAGTCTGCCATGGCTAAACACAAGATGAGACATATACCAAAGAATGAGAGGAAATATTCATGTGCCTCATGCGATAAATTATTTAATACAAAAGATTGTTTGAAATCACATGTGAAAGTGCATATACCCATTGAGGAAAGAAAAATATATCATTGCGATTTATGCAATCTAAGATTTACAAGTCGTTCGTCTGCGGCATCCCACAAGCGCGTGGTGCACGACAAGATCAAGTGCTACGTGTGCGATCTGTGCGGCTACGCGTGCGGCACCAACGGCGAGCTGAGGCAGCATCGCGCCATACACAGCGACGACAAACCCTTCGTATGCTCCAAGTGCTCCAAGCCATTTAAAACATATTCAAATCTGAAAACTCACATGGACACACACGAAGACACGTCGTACGAATGTTTCATCTGCAGACGTGTGCTGAACAGCCGACGAACACTGCGCAAGCACTTGTTAGTGCACGAGGACAAGTGTCGGCACGTGTGTTCTTACTGCAATAAGGCATTCAAGAGAAGACAAACTTTAAAGGTGCACATGTACACGCACACGGGAGACAAGCCGCTGTCGTGCAAGTGGTGCGACGAGCGGTTCTCGTACGCGTCGACGCTGCGCTCGCACCGCCTGCGATGTCACCCGGAGCACATGGCCGCACTGGCCACGCGCAACATACTCAACAATACCGGGTTCATCGCTCAATGCGACACACCAGTGCAATGA
Protein Sequence
MAVDINNMKELCRLCAQNDVFSKDLLEESNKNILNLVQKYIKIAIQDQNYLPTKICLNCEEKIVCFEMFKLECCKVQETFKKICEDSLSSIVKLENPITVFGTPIKSEVKKEAERDMMDVTDVTDEADDVTDDVTEDLVCALTNNDASLTVIDEYPENSEIPLSDHHEDIEADDEYLENLSIASLKKIKRREVTDEEIEAFNEALMKTNLKLKDVIKLNCVFCGEKFKAWKSLRHHCAKRHKARPYVICLCGYLVRSQSTLYKHVGDHRREGRKLRKESGQDVEKKKKKYANLQIKDFVRFNCATCDKACSSWYSLQTHTERVHKLAPILSCVCGLIIKSKSVLYKHIHDHKNPNILRCDKCPKIAKTESAMAKHKMRHIPKNERKYSCASCDKLFNTKDCLKSHVKVHIPIEERKIYHCDLCNLRFTSRSSAASHKRVVHDKIKCYVCDLCGYACGTNGELRQHRAIHSDDKPFVCSKCSKPFKTYSNLKTHMDTHEDTSYECFICRRVLNSRRTLRKHLLVHEDKCRHVCSYCNKAFKRRQTLKVHMYTHTGDKPLSCKWCDERFSYASTLRSHRLRCHPEHMAALATRNILNNTGFIAQCDTPVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-