Malb004953.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Meganola albula
Gene Symbol
ZNF526
Assembly
GCA_936440415.1
Location
CAKZFH010000056.1:349795-389012[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.72 56 4.6 1.5 2 23 482 503 481 503 0.87
2 23 0.00016 0.012 16.1 0.0 1 23 513 536 513 536 0.96
3 23 0.0025 0.19 12.3 2.4 2 23 649 670 649 670 0.98
4 23 0.036 2.8 8.7 3.8 2 23 732 753 731 753 0.95
5 23 3.3 2.6e+02 2.5 3.9 1 23 765 789 765 789 0.90
6 23 0.00024 0.019 15.5 0.5 2 23 796 819 795 819 0.96
7 23 0.037 2.9 8.6 0.2 1 23 825 847 825 847 0.93
8 23 0.019 1.5 9.5 3.0 1 23 853 875 853 875 0.98
9 23 3.2 2.5e+02 2.6 0.0 2 20 886 904 886 906 0.89
10 23 0.073 5.6 7.7 0.1 1 23 985 1007 985 1007 0.98
11 23 2.1 1.6e+02 3.1 7.2 1 23 1014 1036 1014 1036 0.95
12 23 0.0014 0.11 13.1 1.8 1 23 1072 1095 1072 1095 0.95
13 23 0.0054 0.42 11.3 3.8 1 23 1102 1125 1102 1125 0.98
14 23 0.0039 0.3 11.7 0.2 2 23 1146 1168 1145 1168 0.96
15 23 0.002 0.16 12.6 6.1 3 23 1187 1208 1186 1208 0.96
16 23 2.5e-05 0.002 18.6 0.1 2 23 1213 1234 1212 1234 0.96
17 23 0.00029 0.022 15.3 1.4 1 23 1238 1260 1238 1260 0.96
18 23 0.11 8.5 7.2 0.1 1 16 1266 1281 1266 1281 0.92
19 23 0.11 8.5 7.2 0.1 1 16 1313 1328 1313 1328 0.92
20 23 0.11 8.5 7.2 0.1 1 16 1407 1422 1407 1422 0.92
21 23 0.11 8.5 7.2 0.1 1 16 1501 1516 1501 1516 0.92
22 23 9.4e-05 0.0072 16.8 0.1 1 23 1576 1598 1576 1598 0.98
23 23 0.00039 0.03 14.9 0.7 3 23 1606 1627 1604 1627 0.95

Sequence Information

Coding Sequence
ATGGTGGAACCCCAAGCTCCATTGATCTTATGCATGGAGAACGCAAATGGTGAAGAGGTCTCACTTACAATTGAACCAGATGACAATTTTCAGACTTTTTTGGATAAAGCTAGGAACCTTCTGAACTATGATGTAGATCTGAACTCACTCACCCATTACCAGCCCGTCTCTCTCTCCGAAAACATCTACCAATATTTCCTTAACTCTGAACATGATTACCAGAACTTTAATCCTATGTTGGACTTCAACGAAGACAAAGATTTAGTCTACGTATTAGATGATGGCACACAAATACGAGCATCTCAAATACACTTTGATAACGATGACCCGTTAACGGATCTTACAGCTGAGAAAATACCATTTGTCAAATATGCAGATGATATTGACGATAGTTTAGAAAATCTTAGCATTCGTGAAACAAAAAAGATTAACATAGTTGAAAGTCCTGTTTCCAAGTGGTCTAATAACTCAAGTCCTAAATGTAGTTTTGTTAACAGTTTACCATTTAAGTTAGTATGTAATAATACTTCTGGTTTTGAAGCTCAATTCACTAAATATTTGGAGTCCACTAACAAAACTTATGCTACCCTTAACCCCGTTACTACAAGAAATAAATCACCAAAAAGTTTGATCAAAGATAACTTTAAAAACTATGATGATAGTTATACTAGAAATGATAACCTGTCTTACACTAGAGAAGACATTCTAAACATGTTCAAAGATTCTCCAATGACGTCACTGCCATATGACCAAGGGCATTCTGAAAGAAGGCATATCAGAAAGACGGACCCATCAAGAATAGTTCTTAAAAATTGGACGAAACCAATCGCCTATATTGATATCGATGGGGTTTTGATTGGAGAAAGTGAAAGCCAGATATGTTTTATCTGTGGTAAACATGTAGACAATAACATAGACAAGTTATATCTCTTTGATAATGAAGACCAGAGAGTACATAGATGTTCTCCTCAGAAAAAAATGTCTACCCAACTAAAAATTATTTGTGAAGCATGTTTGAATGAGAATTTTAGGCCATGTAGAATGAAAAGTGCGACGCAGTTTTTGAATACCGATGAATATCTTGTTATTAGAAACAACCAGCAGTATATCTTTCAAAAAATAAAGAATTTTAACTTCACACATTTAGGGAAAGCTAAAGAAATCATAAACAAAGTAGAGTCTAAGATAAATAAAGATGAATTTGTTAAAGTTGAAATTGGTTCGGACGGAGAGATAATTACTAAGCCCATAGACAATGATTCGAGGTCTGATGACGTAGTTATTGTTAAAGATTTGAAAAAGGAAGACAGTTCTAGTGATGTGGAGATTATAGAGCCGGAACCGGAAATAGATAACATCATAGATAATTTAGAAGAAGCAGATGAGGAAGTGAAAGAGTTTTTGGGAAAATATCAATGTGATAATAATACAGCTATTGAACTTAAGTGCAGATTTTGTGATAAACAGTTCGCGGATGTGTCGTTAGTGATGGAACACTGCGATACGCATAAACACGATGTAGATGACGACGAAGTATACCCTTGTCCTCTATGTAACTATGGTTACGCAAATCCAAAATGGCTGAAAGCTCACATAAAAGCGGCGCATGAGAATATTAAAAAAAAAGACGAAGACCAGAAAACGGAAGACACTGAAAATGGTGACAGCGAAGATCTGAAGAAAACCTCTTCAGTAGCAGACTGCACTCAGAATAGCAAGAAAACTGATTCTGACAATAAAGAACAAGAAAACACTGAAGATGCCAACCCTGATGAAAATAAACATTCGGATATCATATTTAAGACTGAGGTGAAACAAGAATGCTTGGACAGCAGTGAGGATGAGATCTGGATAGTTCAGACTGTTGATTCTGATGCCACTCAGGACCTGAAGACCTTGCTAGGGACACAGGGGAATTCACAGAACGATACAGAAAAAACTCCCAAATGTAATAATTGCAGTCAAGTATTCCCCACCGCTGGTAGTCTATCATCACACCGCTGTAGACATCGAGGCAAGAAGCGGAAGACTAAGGACGACACTCAGATCTGTATACCCACGGAAGAGGACTTCTTGAAGAGGGCTCAAGGCCGGACTATACAAACAGAGGGATCGACTGATAATAATGATTTGCTTGTTGTGCGCCCAAGGAAGCGTCGGTCCCGAGAACCGACTTCCAACCCTCAAATCGTCACTTGTCACAACTGCAATGAATCATTTACTTCTAAAGTTCGACTCAAGTTCCATATGCAATTCCACGACTTCAACACAAATATTACCCCAGAGGGTAAATATACCTGCACGGAATGTGAACACACCACCTTCAACACTGAGACTGAGCTATTCGACCACGTGCACTTCCAACATGACAAGCAGAAGAGATGGCAGTGTCCTGTCGAGACATGCGGGAAGACTTTCTTCTTAAGAGCAACGTTGACCAAACACAGTCGCACTCACACAGACACGCGGAGGTATGTGTGCGGCACTTGTGGGAAGAGATTCTTGGACAAACAGACATTGGACGAACACGGAGTTACACATCTACAGATCAAGCCGTTCCAATGTCACATCTGCATGAAGCAGCTGACCCGTCGGTCCCGGCTCCGTATGCATGTGCGTGCGCACGAGGAGGAACTGGCGCCCAGACTTGTGCGTGTCTGTGCACTCTGTGCGCGGGCATTCAGAGACTTGGAGCATGCACAGGAGCATGCTACAACATCTACGGAATGTATAGAGGCTTACGCGAACGAGTTGAAAGAGGAGGAAGACGATACAGCAGTACAGCTGTCGCCCACAAGTGGGTTAGTGAGGCACAGCGCTAATGTTTCAGCATCTCCAAAGCTGTCGAAGGTTATAAAGCGCGAAGTATCAGCGGAGCGAGCGGAGCCATTACTCGCTCAGCTGCCGGACGAAGCGAGGCCGCTCATACGGGTTGTGGAGATTGAGAAGGCGTTCCGCTGCGAGTATTGCGAGGATGTGTTCTACTTGGACAGCGGTTTGAACGCACATCGGCTGATACACAAGAATGTCAAAAATCCCTTCACCTGTCACATCTGTAAAGTCAGCTTCGCTACTTATTCTAGATGCACAACCCACAAGACTACCCACGGGTTCTACAAGCGCTCCCTGGCGGACGCCAAGAAGCAAGCTGTGGGTCACACACACTCTGCCTCCGGTATACTAGGATACGGGGATTTCCCTGTAGTCAAACATTTCCTGTGCGAGGACTGTGGCCGTTCGTACTTGCACTGGACGTATTTACAAGTACACAGACGTATGAAACACGCGAATGAAAACTTTCTATACAAGTGTAACCAGTGTGAACTCACCTTTCATAATAGTTGGAGTTTGTCGTACCACCGTAAGAAAGTGCACGGTAAGACAGGACCGGATGAATCCGGGACTACAAAGGTATGCCGGGAAGATTACAGGATCCCGTGCCGTGATTGTGACGAGGTGTTACCTAACAAGACGGCGCTATACAAACACAGGAAGAAGGAACACAGCGATCTGTCTCTGCAGCTGAAACCAGGTGAACTGACGACAAGTGGTGGAGCATGTCCACATTGTCACGCGACGTTTACACACGACGAGGATCTACAGAAACATATAAGGGAATGTCACGGCACATCGATAACGTGCGCCTCGTGCGGCAAGCGGTTCTCGTCCCGCGGCGAGCTGGCCGCGCACGTGCGTGTGCACGCGCGGAGACACGCGTGCCCCGTGTGTGGGCACGCCTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGGATATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGGTACTACACACTTCCGCACGCTGTCCATGCGCCGCGAGCACCTGCGCGTGCACACCGGCGAGCGGCCCTACCCCTGCGACGTGTGCGGCGTCGCCTTCCGCAGATCGACAGCGATGCGTAACCACCGTCTCATACACACCGGCGTCAGGGCGTGGGCTTGTGGTCGATGTCCGAAGAGATTCCGTATTCGTTCTGACTTGCGGACACATTTGCGGCTGAAACATCCCGCCACTATTGTTGTACTGGAAATGGAAGGTTTAAACCCGACGTCGCAAGAGGTGATGAAGCACTTAGAAATGAACAACATACCCCACGACAAGATCATCGAGATCACTAAGATATCATTCGCTAAGGGCAGCACGCAAGTGGTACCAAATAGTGCGCGTGCGCTCTCCGCGCTAAGTGCCGCGCCAAGGACCAGCCTACGTACTGACACTACTCCACACAACAATATGGAAGAATATCAACCGGCTCGTCGTGGTCGGGGCATAGCGAAGAACCCACGCCGCCCAAAGATATTGCAAAGAGGAGACACGCCACAAGACTCTGCTTACCCTCTAGCTAACGAACCTGTTAATAATGTAAGGATAACAATAAACTGTCTCGGTGGTTCAGTGGAACTATGCGACTTGAACGTGCAACTGTTGCTCCGTGACGGAATACTAGTAAATGGAAACCAGATGGTACAGCTTCATCTCGACGACCCGATGCTGTTAGAGTGA
Protein Sequence
MVEPQAPLILCMENANGEEVSLTIEPDDNFQTFLDKARNLLNYDVDLNSLTHYQPVSLSENIYQYFLNSEHDYQNFNPMLDFNEDKDLVYVLDDGTQIRASQIHFDNDDPLTDLTAEKIPFVKYADDIDDSLENLSIRETKKINIVESPVSKWSNNSSPKCSFVNSLPFKLVCNNTSGFEAQFTKYLESTNKTYATLNPVTTRNKSPKSLIKDNFKNYDDSYTRNDNLSYTREDILNMFKDSPMTSLPYDQGHSERRHIRKTDPSRIVLKNWTKPIAYIDIDGVLIGESESQICFICGKHVDNNIDKLYLFDNEDQRVHRCSPQKKMSTQLKIICEACLNENFRPCRMKSATQFLNTDEYLVIRNNQQYIFQKIKNFNFTHLGKAKEIINKVESKINKDEFVKVEIGSDGEIITKPIDNDSRSDDVVIVKDLKKEDSSSDVEIIEPEPEIDNIIDNLEEADEEVKEFLGKYQCDNNTAIELKCRFCDKQFADVSLVMEHCDTHKHDVDDDEVYPCPLCNYGYANPKWLKAHIKAAHENIKKKDEDQKTEDTENGDSEDLKKTSSVADCTQNSKKTDSDNKEQENTEDANPDENKHSDIIFKTEVKQECLDSSEDEIWIVQTVDSDATQDLKTLLGTQGNSQNDTEKTPKCNNCSQVFPTAGSLSSHRCRHRGKKRKTKDDTQICIPTEEDFLKRAQGRTIQTEGSTDNNDLLVVRPRKRRSREPTSNPQIVTCHNCNESFTSKVRLKFHMQFHDFNTNITPEGKYTCTECEHTTFNTETELFDHVHFQHDKQKRWQCPVETCGKTFFLRATLTKHSRTHTDTRRYVCGTCGKRFLDKQTLDEHGVTHLQIKPFQCHICMKQLTRRSRLRMHVRAHEEELAPRLVRVCALCARAFRDLEHAQEHATTSTECIEAYANELKEEEDDTAVQLSPTSGLVRHSANVSASPKLSKVIKREVSAERAEPLLAQLPDEARPLIRVVEIEKAFRCEYCEDVFYLDSGLNAHRLIHKNVKNPFTCHICKVSFATYSRCTTHKTTHGFYKRSLADAKKQAVGHTHSASGILGYGDFPVVKHFLCEDCGRSYLHWTYLQVHRRMKHANENFLYKCNQCELTFHNSWSLSYHRKKVHGKTGPDESGTTKVCREDYRIPCRDCDEVLPNKTALYKHRKKEHSDLSLQLKPGELTTSGGACPHCHATFTHDEDLQKHIRECHGTSITCASCGKRFSSRGELAAHVRVHARRHACPVCGHAFRTLSMRREHLRVHTGERPYPCDVCGVAFRRYYTLPQVLHTSAGTTHFRTLSMRREHLRVHTGERPYPCDVCGVAFRRYYTLPQVLHTSAGTTHFRRYYTLPHAVHAPRAPARAHRRAALPLRRVRRRLPQVLHTSAGTTHFRTLDMRREHLRVHTGERPYPCDVCGVAFRRYYTLPQVLHTSARCPCAASTCACTPASGPTPATCAASPSAGTTHFRRYYTLPQVLHTSAGTTHFRTLSMRREHLRVHTGERPYPCDVCGVAFRRYYTLPQVLHTSARCPCAASTCACTPASGPTPATCAASPSAGTTHFRTLSMRREHLRVHTGERPYPCDVCGVAFRRSTAMRNHRLIHTGVRAWACGRCPKRFRIRSDLRTHLRLKHPATIVVLEMEGLNPTSQEVMKHLEMNNIPHDKIIEITKISFAKGSTQVVPNSARALSALSAAPRTSLRTDTTPHNNMEEYQPARRGRGIAKNPRRPKILQRGDTPQDSAYPLANEPVNNVRITINCLGGSVELCDLNVQLLLRDGILVNGNQMVQLHLDDPMLLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-