Mdol000524.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978525.1:12280673-12290495[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00021 0.02 16.2 0.7 1 23 120 142 120 142 0.98 2 14 0.013 1.2 10.6 0.5 2 23 398 419 397 419 0.97 3 14 4.4 4.2e+02 2.6 4.1 1 23 425 448 425 448 0.94 4 14 0.25 24 6.5 2.6 1 23 472 495 472 495 0.94 5 14 4.8e-05 0.0046 18.2 2.3 2 23 529 550 528 550 0.97 6 14 0.041 3.9 9.0 3.1 3 23 696 716 695 716 0.97 7 14 0.0072 0.69 11.4 0.7 1 23 722 745 722 745 0.96 8 14 0.48 46 5.6 0.5 2 23 781 803 780 803 0.96 9 14 0.65 63 5.2 0.3 1 23 817 840 817 840 0.95 10 14 0.0044 0.42 12.1 3.3 1 23 1002 1024 1002 1024 0.98 11 14 0.0011 0.1 14.0 0.6 1 23 1029 1051 1029 1051 0.97 12 14 0.013 1.3 10.6 10.5 1 23 1057 1080 1057 1080 0.97 13 14 0.0027 0.26 12.7 0.0 1 19 1085 1105 1085 1105 0.97 14 14 0.0029 0.28 12.6 3.0 1 23 1115 1138 1115 1138 0.97
Sequence Information
- Coding Sequence
- ATGGACGAAAACCCCAGTATTGATTATAGATTAGTGTGCCGTACGTGCCTCACATCGGATGCCGAGTTTTATAAATTGGATGCACCTCTTATTTCGggcaatgaaaaaattaatatcatagacTGTTTACGGTATTGCACACGCTTGGATGATGCGCCTGATTTTCCGTTTTACATTTGTACCAAATGCTGCAGTGATCTACAGGTAGCATACACGTTCATACGTAACGCCATTGAAGCGCACGATATCCTACGTCAGAAATTATGTCCCATACAACGTAATAATGGACTGAATGTTAAGAATAATAATACAGTAGCCAAATGCGAGTTTAAGATCAGTGACGAAAAACTTATGCGATTTCGATGTAAAATTTGCGGTGAAAAAGTTGACTCGAAGAAATCATTAAAAGATCATGTCAAACTGCATATGGATATTATTTCGTATTGCTGCCAATTGTgtacatatgaaagtaaaaAACGTAACATTTTAAGTGACCATTATAGTGTCGTTCATGGTACACAGGCTACACGGGAGCAATTAAAACCAAAAACAGCACAATTAACAGATAGTAAAACAGAAGAAATAGAAGCAGGAATAATAGATCCAAATACAGCAAATGCCGAGCAACAATTCATAATagcatcacaacaacaacaacagccggAACAACAGAATATATTCCTACAACATCAAAATCAACATTTACCATATGGCAGCAATAACATTGAAGGACAGCTTCAGCATCAAGTTGTTCAAGGGGAGCAAATTAATTTTACCAATCACATAATATCGTCCGCAAATAATATCAATGTGAATACAATATCGGCAGATGCAATACAAATGGAAGAATGCGGCAATGAATATAATATAGCAAATGAAATGTGCATTGGAAATGAATTTATTGTAATGGCTGATGGCACAGTGGAGGAAGTTATGGGAAATGGTGttgtaattgaatatattaatgCGACAGATGATGGCGTTAAATTGGCAGATGATTTAgcttttaataatattgtacaaatggATACAAATGATGCTGCCGCAATGTTAAATTTGAACGTAGAGGATATTATAATAGAAGAAAATGTACCAAGTGAAGTTAATAATGAAGCTAGTGTAAATACAGAAACTAATTTAGAAGACGAAATACCACAGGCCGTCATCGTAGTATCGAAcgcaaaaaaaatcaaatgtaaaatatgcGCAAATAATTTTGATACACAAGATAAACTAAAACCTCATATGTTGACACATAATGAGATTCCACACTTCTTTTGTGATCAGTgcacattttatacatttttcaagaTTGATTTAACTCAacattacaaaacaaaacacaatctACAGCCGACATTTAAACAATTACAACCGAAAAATAAGGTTGCCGAGATTGAATCCAAAGAAACATATGCATGTGATTTATGCCTGTTTGAGACAAATCTGAAATCACATTTGCGACGGCATTACTTGAGTAAACACAAGGTAGAAGCCACCGAAATACAATTACGACCTGCTACTGCCAATGAAGGCGTTATGtctaatagtaataacaatatcGACTTAAAACCCAGTGGAGTTAGCTGTAAGAAATGCAAGAAAGTATTTTATTCTCGTAGTAAACTTACAGATCACTATAAAGTGCATAATTTAAGTGATAGCTATCAATTAACAACAACGAATTCATCTAtaacaagcacacacacaccagATTCATCATATGCAAAAGTAATAGtgcagaataataataatggaatgAAAATAGTGAATAGAACGGAAATGGTGCCAATGGTATCAACATATAACTCAATACCCGCAGATAGTATACCACAAATTGTTGAAACCGACCGAACGGTTGATACCAATGATATGGACTTTGATTTTAACGGCGAAACATTCTTCGAAGATTTCTATGGTGATACTGAAATCAATAATGAGGacaatgaagaagaagatgacgatgatgaagTTCAGGATCTTCATTTGACAAGTGATGATGACAATGTCGATGAGCTACTTCAAGATAAACAACAACAGGCACAAAATGCAGTCGGCGACGACAATAAACAATACAAGGCATTTTGTGTGCATTGCAATAAGAACTTTTTAAGTCAGTATCAGTTTGAGAATCACATGTTTATCCATCGAGGTTTAGCACCATATCGTTGTGAAATGTGcacaaatttatacaatacaaaacgTGCACTAATTAGACATTATAGGGCAGTGCATAAGAAAATACCCACCAGAGATATGATACAAGCGAAAGGTGATAAAGTAACATTTGATAGAACGCCAGTAGAGCATTTAATTTTGGAAGAACAAAAGGcaacTTTAATGTGCGCCAAATGCCCTTATGAATCGACTGAATTgcataatatacaaatacatttaaatacaaGCCATGGATTAAATGAtgaGAATTACATTCTACAAAagctGCCATATGAATGTCCTCGTTGTATACGTTCGTATGCAACCAAATTACGTCTAATTTATCATTTGGAAAGTAGTCATTCGGCAACAGTCATACAACAACGCCAGTCATCATCCACAACAATGACGACGGCAAGACCATTCGATACAATTGAATGTGCTACAACAATGCCACCCAGCATTCGAAGTGACACCAATTTAGATCGTAGACAAAGCAACACAGCAGCAACATccatacaccaacaacaactacaaacgACTACAATCAAAACAtccccaacaacaacaacaacaatatcatcatcatcatccgccgccgccgccgcagattcaataataaaagaagaagaagaagagtatACTACAAATGTTGTATACTACAATGATAGTGATACCAACGACACCACTAGCACCACAACCACCACAACCGCCACCATCACCAACAATACGATGGAAGTAAATCAATTGAAATGTAAAGCATGCCAATTTATctgtaataaaattgaaacattaaACGAGCACAGCAAACATCATTCGAGCAATGATAAGCGtagtaatttcaattttgaatgtGTCATCTGCCAATGCAAATACAAGACGATCGAATCGCTAAAACAACATTTGAAACGTCATATAGGGCGTAAATACTCATGTCCGCAATGTCCGAAAGCGTATATTAAtcgaaatgaattgaaatgtcACATATTGGTACATACCGGCGAAATGCCATACAAATGTCATTTATGTTGCAAAGAATTTCGTTATAAACATCATCTGAAGCGACATATGGATGTTGCGCATCTTGGTAAACGATACATGTGTCCGATGGCCGGATGTGAGCGTACATTCGCAACAAAGGCTCAACTGAAAATACATGACTGGGATCATAATGGTAATATACCATATAAATGCCAGTATTGCAAGCAAACTTTAAAAAAGCGTCAATTaCTACGTCAACATGTTCAAAAAGTGCATAATGTCATACTAACAGAAGATGATATTGCTGAAATCTATCGCAACAATGTTGGCTATACGAATCCACATGATTTCACAGTAACCGTTTCAAATGGTAAAATGTTGCGCCGTTCCGATGTCGGAACAAAAATTCTTTCTAAGAGATCAAGATGA
- Protein Sequence
- MDENPSIDYRLVCRTCLTSDAEFYKLDAPLISGNEKINIIDCLRYCTRLDDAPDFPFYICTKCCSDLQVAYTFIRNAIEAHDILRQKLCPIQRNNGLNVKNNNTVAKCEFKISDEKLMRFRCKICGEKVDSKKSLKDHVKLHMDIISYCCQLCTYESKKRNILSDHYSVVHGTQATREQLKPKTAQLTDSKTEEIEAGIIDPNTANAEQQFIIASQQQQQPEQQNIFLQHQNQHLPYGSNNIEGQLQHQVVQGEQINFTNHIISSANNINVNTISADAIQMEECGNEYNIANEMCIGNEFIVMADGTVEEVMGNGVVIEYINATDDGVKLADDLAFNNIVQMDTNDAAAMLNLNVEDIIIEENVPSEVNNEASVNTETNLEDEIPQAVIVVSNAKKIKCKICANNFDTQDKLKPHMLTHNEIPHFFCDQCTFYTFFKIDLTQHYKTKHNLQPTFKQLQPKNKVAEIESKETYACDLCLFETNLKSHLRRHYLSKHKVEATEIQLRPATANEGVMSNSNNNIDLKPSGVSCKKCKKVFYSRSKLTDHYKVHNLSDSYQLTTTNSSITSTHTPDSSYAKVIVQNNNNGMKIVNRTEMVPMVSTYNSIPADSIPQIVETDRTVDTNDMDFDFNGETFFEDFYGDTEINNEDNEEEDDDDEVQDLHLTSDDDNVDELLQDKQQQAQNAVGDDNKQYKAFCVHCNKNFLSQYQFENHMFIHRGLAPYRCEMCTNLYNTKRALIRHYRAVHKKIPTRDMIQAKGDKVTFDRTPVEHLILEEQKATLMCAKCPYESTELHNIQIHLNTSHGLNDENYILQKLPYECPRCIRSYATKLRLIYHLESSHSATVIQQRQSSSTTMTTARPFDTIECATTMPPSIRSDTNLDRRQSNTAATSIHQQQLQTTTIKTSPTTTTTISSSSSAAAAADSIIKEEEEEYTTNVVYYNDSDTNDTTSTTTTTTATITNNTMEVNQLKCKACQFICNKIETLNEHSKHHSSNDKRSNFNFECVICQCKYKTIESLKQHLKRHIGRKYSCPQCPKAYINRNELKCHILVHTGEMPYKCHLCCKEFRYKHHLKRHMDVAHLGKRYMCPMAGCERTFATKAQLKIHDWDHNGNIPYKCQYCKQTLKKRQLLRQHVQKVHNVILTEDDIAEIYRNNVGYTNPHDFTVTVSNGKMLRRSDVGTKILSKRSR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -