Basic Information

Insect: Megamerina dolium
Gene Symbol: -
Assembly: GCA_963854835.1
Location: OY978526.1:40558317-40568655[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.073 7 8.2 0.9 1 23 1724 1747 1724 1747 0.97

2 13 9.3 8.9e+02 1.6 1.0 1 23 1925 1947 1925 1947 0.93

3 13 0.00079 0.076 14.4 2.8 2 23 1950 1971 1950 1971 0.97

4 13 3e-05 0.0029 18.9 0.2 3 23 1979 1999 1977 1999 0.98

5 13 1.6e-05 0.0016 19.7 6.2 2 23 2006 2027 2005 2027 0.97

6 13 9.1 8.7e+02 1.6 0.4 5 23 2040 2058 2038 2058 0.96

7 13 2.3 2.2e+02 3.5 5.4 3 23 2065 2086 2063 2086 0.93

8 13 0.062 6 8.4 0.1 2 23 2097 2117 2096 2117 0.96

9 13 3.3e-05 0.0032 18.7 0.8 1 19 2123 2141 2123 2145 0.94

10 13 9.6e-06 0.00092 20.4 1.2 1 23 2153 2175 2153 2175 0.98

11 13 0.00017 0.017 16.5 7.6 1 23 2181 2203 2181 2204 0.96

12 13 0.0016 0.15 13.4 6.5 1 23 2209 2231 2209 2231 0.98

13 13 0.0028 0.27 12.7 6.0 1 23 2237 2259 2237 2260 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.073	7	8.2	0.9	1	23	1724	1747	1724	1747	0.97
2	13	9.3	8.9e+02	1.6	1.0	1	23	1925	1947	1925	1947	0.93
3	13	0.00079	0.076	14.4	2.8	2	23	1950	1971	1950	1971	0.97
4	13	3e-05	0.0029	18.9	0.2	3	23	1979	1999	1977	1999	0.98
5	13	1.6e-05	0.0016	19.7	6.2	2	23	2006	2027	2005	2027	0.97
6	13	9.1	8.7e+02	1.6	0.4	5	23	2040	2058	2038	2058	0.96
7	13	2.3	2.2e+02	3.5	5.4	3	23	2065	2086	2063	2086	0.93
8	13	0.062	6	8.4	0.1	2	23	2097	2117	2096	2117	0.96
9	13	3.3e-05	0.0032	18.7	0.8	1	19	2123	2141	2123	2145	0.94
10	13	9.6e-06	0.00092	20.4	1.2	1	23	2153	2175	2153	2175	0.98
11	13	0.00017	0.017	16.5	7.6	1	23	2181	2203	2181	2204	0.96
12	13	0.0016	0.15	13.4	6.5	1	23	2209	2231	2209	2231	0.98
13	13	0.0028	0.27	12.7	6.0	1	23	2237	2259	2237	2260	0.96

Sequence Information

Coding Sequence: ATGGTGGAGAACGTACAGTGCCCTGTGTGCACGTTATTCCTGCACGCGGGTATGAATCTGTCCGATCATTTGGAGACGCATCCCAAGGAGCAAGTGATTAAAGCACTTGTTCATATGATGATACCGGGTGGTGGAATTGGCAGCAGTGCTCTAGCCGCAGTATTAGCAGAACATAAAAAACCTGAAACCACCACAACAAATGCGAAGCCCATACAAATTCAGAAGGAGCCAACTTCGAGTGATCACTCAACAGCTACTGCTAGAACGGGGAATAATAACGGCGCATCGAGTGTAAAGGATGCCAACTTTGCGAAAAGTTTCTCAGCAGCGGCTGCACCATCTACTGCAACAGCAATAGCACTTGCGTCGTCGTCTAGTTCGGACACAATTCACTGCCCCTCAATAACCACTAAGACAGCTGTTTGCGTTGACGCTACTGTTGCCGGCACaacatcgccatcatcatcatcatcgtcatcgtcatcagtTGGTAGTGGCGGCGTCGCAAGTGCTGCTGGCAGTGTGGTGGAGAAGATTATGTACAATCAATCGGTTTTGAATTCATCATCCACAGCATATCAACGTAGTTTCAACACTGTAGTGGCCACATCGGCACCGCTAGCCATTGCCAGTGTTAATGAGGTCGCAAGTGTGCCAACTGATTTTAGAACATTTGCTGCTACTAGTCGCTACCAACAAACGCAGCGAAATGTTACAATAAGTCAATtaccgcagcagcagcagcagcagcagcaacaacaactgccAACTACTCTTCAACATGTTGTACTTGCTCATCAGCAGCATCGCACATCattactaccaccaccaccacctccaccgccaccaccaccaccaccaccactaccgccGATGCCATCGAATACAATTTCGCAGCTATCATCCACGACGACAGCATTTCAtggacagcagcagcagcagcatggatTACTTGCAACAGCAATAGCACCAACCATACATCTTCGTAATCAGCATGTACAACAACCGCAGCcacagcatcaacaacagcaacagcagaatCTAAAAATCTCCTACTCTTCAACTATATCACCACCACCTCCACTACAACTTTTCTCCTATCAACCACAGCCGCAAGCTCAACATCAGAAACCACCGCCAGCTTATGGCACAGCAATCAGTCAAATACGATCTCAACATAGCCAAAATAAACCACATCATGTTACGATGTCTACAcagaagcagcaacaacaacagcagccgcAGCAGCCACAGcaacagctgcagcagcagcagcaacaccaccaccaccaccaccaccatcatcaacagcatcatcatcagccgCATCACTTGCGTGTTGCACATCCTGCAACAACAGTAGCATCAATATCAAAGAATCACATGTTGCAACAAACTCACAAACAGATTGGGCCTTCCCTAACGACAGCGCCAGTTTTCCCGATTTCGATTGCTCGTGCACCACAGCAACAATTTTTCAGCACCATTACAACAAGCAGTGCTGCTTCGTGCTCTAAATTGGCCACTAGTGCCCACCAGCGTTCATCAATGGTTTCGGTAacggtggcggcggcggcggcgacgGCGACGGCTTCAACTCCTGCACCCCAACAAGTACTGACACAACAACAGCCTTCAACAACAAGCGCCATCAGTCATCAGACAAATTCACAATCATTTAGCAGTTTCCtagctgccgctgctgctgctgctgctgctgctgctggatCCACACCATCACCATCGTCCGTTCTGCGTTACGCTGAATCACCGGTGGCGCATTATTTGGAACGCGATAATGGCGACTTTATCGTACAGGAGACACCGAAGCACATCGTGGAGTGTGTTGAAAAGGATAATGGTGAATTTTCTGTTATAGAACGCATTTACCAGTCACCACCGAGTGTATTGCACATACACGACGAAGACGAAGatggagatgatgatgatgatgacggcgAGATCGAATGCAAGCAGGAGGGCGACGAAGAGTTCTTGGAGTTGAGAGCTCTCGAGAAAGGCGACGATCACAATAAATCAGATTTGCAAATCGACGATGAGGAGGAGTTCATGAGCATAGCCAGTGATAGCGATCAAGATGAAGTTGCCACAGTCGAAAACCAAGCCAAGAAGGAAGATCTTGGGAAGCAATCGGCTAGTgagcaaagacgaatgagcacCGAACCCTCAactagtagcagtagtagtgcAGCGACAGCGGCGACTGCTGATCAAACGGCTGGTACAACAGTTAATGGTGCCACTCCTACGCACACCAATAATGCTGCGACCATCCTTAATTCCAATTCCAATTCGAGCTCCAGCAATTCGACAGTGAGTCGAAAGAAATCCTCCAAAAATACAATAACGGTTTTGAGTGATGTACACTTGAATCTGAACGAATACCTAGATTTAGTGGGTAATATTATTGCGTCAAGTAAGATAGGCACACAACGGCCGGCATTTACAGCAAGAGCGCCTATTCCGCTGTTGAAAGTTGAGAAGATTGAGCCTCCCGACGAATACGAAATGCAGCATACGAACACCGATGAACACAACGATGAAATGGATGCATCGACTGAGGAAGCAACAGCAGCGACTGAAGTGCTAGATGAAGCAACCACGGAACCACCTAAAATAGCCAATAAAAATGAGACTGATGAAttagttgaaataaattgtaagaACGATAATATGTCTaacttaaaagcgaatcacgGCGGtaatggcgatgatgatgatgccgatGTCGAAATGAGTCCTACTACGGCTGCGTTATCGCACGAGCAGAGTAAAGAACACTTGACAGCAACAGCtttaaatgtacaaaatgtTGCAACAACAGCATGTTCCAGTCATGTGACAAGTGTCATTCGTATGGCTACAACTagtcagcagcaacagcaacagcaacagcaacaacaagaacagcacTATTCGACAGAACTGAAAGTTGAACATGTGCCCGTAGCTGTGCCACAAACTGTAACAGCGAAAGAAGAATATGTTGCACAAGACTTGTCGCAATCACAATTCAAATTGGAAGACGACCAACAGCAGCAGATTCAGCAGCGTAGGATTCCCGTACAATCACAACCACCACCGGTAAAGAAGGGTCCAAAGAAGTTAGTAATTAAAccaaaatcatcaataaagaCTGATTCAAATGCCAGCAAtaaagtagcagcagcagcagacaCACTGCCCAACGATGAGCAGCCAACCACATCGGCAATGGCACAAATGAAATTGCTGTCCAGCGTGAAGGAGAATGAATCACCAAAGTATGACAAGGAACACGATCTCACAACGATTCAGAGAATTGTCATTAAGAATGAACCCTACGAGAATGGTGGCTATGCCAACAGTAGCATTTTGGAGCAACATTTGAAATTAGGCTCATCACAAGCAACACCCATCGAATGTAAAAAGGAGAAATCATCCCCGGTTGATGTGAAAACTCAACTCAAGTTCGAAGCGAAAGAGAGTCAGGAGAGTGTGCTGGAGTTTCAAGTTTCAAGCGATGAAACGACATCACGTAAGCATGCAGCCGAAAATGTTGCAGACGATGCGCGTGTGCTGTTGGATTTTGCCAATTCTTCAAAGAAGCACCATACTTGTTCTACCAGCGGCGTGAATTTTCTCTCTTCCACCTCGATATTTTCAAGTGCTGCCATATCGATGGCAACAGCGTCAAATGCaaacaccaacaccaccagcACAACATCAACTCCAACGGTCACAGCGGCCATTTGCAGCAATTCGTCATCGCTCTCAAGTCATTCGCTACACTGTGAGGACGAGTTTATTGCAAACGATGTTGTGCAGGAAATTGTCATCTCCTCATCGTATTCCTCGCAATCGGCATCTGATGCTTTGTGCATCAATCAGACAACGAACGCTTCAAACCAAACGCATCAGCAGTCGTTGCACTCTTTCAACGATTATCCATTCAGTTTCCTTTATGGTGCCAACAACGTTGCACAACAGATTGATACAAAAAGTACTTTTGCACCGATctatcagcagcaacagcagcatcaacagcatGATGTTGGCGCTGCTGCAGTGTCTGTTATGTCGGGCAGTAATTCCGCTGTTACGATTGAGGATTCAACATCAGCACATGTGCACTCACAATCGCAATCAAATCGCCATTCGGCTCAATGGTATCACCATCATGCCGCCGCCACAGCAAACTCAGACTTTGAGGCTGCACTGGCTGTAGATTGCAATGCTGCCGTGGACAGTGGTGACGTCAGTAAGTATCTCGATTTGGATGCATGCAAGCGTGAGGGCGGTATTGGCAACAGTGTGCAGACGGCACCCTCTTCTTCCACATCGTCCTCATTCACAATAGTCACCGACAGCAGTTTAGCCGGTGGTTGCACAACGGCAGACGCTCTAAATATACGTACCGATGAGAAAATGCCAGCCAAGGGGGAAATATCTGAACAGGAAAGCAACTGTGACATTGAGAATTCGTGGAGTCAGCCGATGTATGGCGATTCGACACGTTTCTTTAAGACATCATTTCCTGGAATCTTTCAGCAGGATCAAGGTTGGAATCATGAAGAATATTTTACTGTACAGGATTTAAGTGCTTCAACTGCGgccgccgccgccgctgctgctgctgctgctactgctggcAGTACTAATGCTGCCAACGGTAGATCAAACAAGAGctTTGATTTTCGCCTTCCATTGGAAGCAACTACCTCAGCCACGGCAAACGGCAGCAATTCGAACAGTAATCAACTACAATTATTTCCACAGCATGGCGATACAGTATTGCCATCAACATCTACCAACAAGAAGAAACGTAGGCGTGAGACACACGCTGATAAACCAACTTCCACACGAATACAACCGACAGCAACGATTACGTCGCAGCAAATGTTGCTGCATCAGCcaatacaacagcaacaccatcaacatcatcatcatcagcagcatcatctTCATAATCACTTACAACAACCATCCCAACAGCCTGTATTGCATATACAATTgcagcaccaacagcaacatcatcaacaacaaaatccatCGACATCTGCAGCATTGATGGCTGGTCCATCAacagctgctgctgccgctgcagCTGCTGCCAGTGGTGTTGCCACAGCAATGAcgattcaacaacaaaagccacGCAAAAAGATCTTTCAATGCGCACACTGCTCCGCCAAATTTCCAAAGCTTAAAGATCGCAATTCGCACATGATTGTCGTGCATAATTATGTGCGTCAAAATCGTCGTCTCATTTGTACAACAAATGCACTGGCTCAAGCGACAGCAACTGCCACTGCTGCAGATTTGATGGCGACTTCTGGGGCAGCGTCTTCCAGCAGTGGTATTCCACATATGATGCTCGATGCACAAAATGGCGAATTCATGGAGGATTCCAAACAGGGTATTGTTAAAATCGAGATGGACATTTCCCCACAACCCACTTCTATGGCGATGAGCAATGAAAACATTTCAACTAAATCAGAGTTTATCGATGAGAAGGAGAACATGGCATTGATACCAGTGAATGGTTCAACAGGAGTTGCAACAGTTGATGCTGCAACTGCAGCGGCCGGCACCAATGCAATTAGTAACAATCAGGAAGATACGAAACCCACCTTGCAACCACTGTCGGTTACCACACCAGCAACTAAGCTGGCCACTTTGTACCGCATGCTGGTTTCCTATAATATTTCAACGCTGAAACAGAGTCAGACTTTGACTGAAGTCGAGGAGAAATTAATCGAAACATCGATATTCTTTTGCTACGTATGCCGTAACAATTTTAGTTCAGTGAAATTATACGACGCTCATCTTACGGAACATCCAGCAGAGTGTTTCACATGTGGCAAGAAATTTCAACGTTGGAAGAATTTTTCATTGCATCTGAAACGTCATTTGGGTTGGAAGGAGTTTGGTTGTAATGTGTGCGATAAAAAGTTTGTTGTTCGTAGTGCACTCGTTGAACACATGCGAATGCATACAGGTCAAACGCCATTAAAATGTAAACTTTGTGGCAAACACTTTAAGCGCTATTCAAATCTAACGCAACATCGTAAACGTCACGGCAAGATGATTGTACGCAAGAAGGAGTATGTGTGCCACTGTGGCGAAGTGTTGCCGTCGAAGGCACGTTTCTTGTGGCACAAGGAGACACATGATGCCAAACCGAAATGTTGTCCCTATTGTTGTGATCGTTTTGTGCATGCAAATTCACTGCGTCGCCATATACGATTGGCGCATTCGGACAAATTCGACTATACCGAACCGATGGAGTGTCCCATGTGTAAGCAGATATTTGCCAAATCGTCGATAAAGGCTCACATGGCCACACATTCGATGGACACACAACATGATTGTCCCATTTGTAATAAGTCATTCTCGACCAAATGGAATTTAAAGATACATTCATGGGTGCATGCAAATCGCACCGCCAAACCATTCAAATGTGAACATTGTCCCAAGGCGTTTGTACGCGAGGTCGACTTTAAGAATCATATGAATGCGCACAAGCAAATTAAACCGTATACATGCGAGTATTGTGGCTGTAAATTCATACGCAAATACAATTATATGCGACATCGACGCGAACATCATGGCAATAAGAAGTTCACCTGTGATTTGTGTAAAAAGTCGTTCCATCGCCACTACTATCTGATCGAACATCGACGTATACATACGGGCGAACGGCCCTTCCAATGCACCATCTGTGGTAAGAGTTCAACAACGAAAACCAATCATAACAAACACTTGAAGATACACCATTCGCGTGATCCATTTACGGTGGAGGCGTAA
Protein Sequence: MVENVQCPVCTLFLHAGMNLSDHLETHPKEQVIKALVHMMIPGGGIGSSALAAVLAEHKKPETTTTNAKPIQIQKEPTSSDHSTATARTGNNNGASSVKDANFAKSFSAAAAPSTATAIALASSSSSDTIHCPSITTKTAVCVDATVAGTTSPSSSSSSSSSVGSGGVASAAGSVVEKIMYNQSVLNSSSTAYQRSFNTVVATSAPLAIASVNEVASVPTDFRTFAATSRYQQTQRNVTISQLPQQQQQQQQQQLPTTLQHVVLAHQQHRTSLLPPPPPPPPPPPPPPLPPMPSNTISQLSSTTTAFHGQQQQQHGLLATAIAPTIHLRNQHVQQPQPQHQQQQQQNLKISYSSTISPPPPLQLFSYQPQPQAQHQKPPPAYGTAISQIRSQHSQNKPHHVTMSTQKQQQQQQPQQPQQQLQQQQQHHHHHHHHHQQHHHQPHHLRVAHPATTVASISKNHMLQQTHKQIGPSLTTAPVFPISIARAPQQQFFSTITTSSAASCSKLATSAHQRSSMVSVTVAAAAATATASTPAPQQVLTQQQPSTTSAISHQTNSQSFSSFLAAAAAAAAAAAGSTPSPSSVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDNGEFSVIERIYQSPPSVLHIHDEDEDGDDDDDDGEIECKQEGDEEFLELRALEKGDDHNKSDLQIDDEEEFMSIASDSDQDEVATVENQAKKEDLGKQSASEQRRMSTEPSTSSSSSAATAATADQTAGTTVNGATPTHTNNAATILNSNSNSSSSNSTVSRKKSSKNTITVLSDVHLNLNEYLDLVGNIIASSKIGTQRPAFTARAPIPLLKVEKIEPPDEYEMQHTNTDEHNDEMDASTEEATAATEVLDEATTEPPKIANKNETDELVEINCKNDNMSNLKANHGGNGDDDDADVEMSPTTAALSHEQSKEHLTATALNVQNVATTACSSHVTSVIRMATTSQQQQQQQQQQQEQHYSTELKVEHVPVAVPQTVTAKEEYVAQDLSQSQFKLEDDQQQQIQQRRIPVQSQPPPVKKGPKKLVIKPKSSIKTDSNASNKVAAAADTLPNDEQPTTSAMAQMKLLSSVKENESPKYDKEHDLTTIQRIVIKNEPYENGGYANSSILEQHLKLGSSQATPIECKKEKSSPVDVKTQLKFEAKESQESVLEFQVSSDETTSRKHAAENVADDARVLLDFANSSKKHHTCSTSGVNFLSSTSIFSSAAISMATASNANTNTTSTTSTPTVTAAICSNSSSLSSHSLHCEDEFIANDVVQEIVISSSYSSQSASDALCINQTTNASNQTHQQSLHSFNDYPFSFLYGANNVAQQIDTKSTFAPIYQQQQQHQQHDVGAAAVSVMSGSNSAVTIEDSTSAHVHSQSQSNRHSAQWYHHHAAATANSDFEAALAVDCNAAVDSGDVSKYLDLDACKREGGIGNSVQTAPSSSTSSSFTIVTDSSLAGGCTTADALNIRTDEKMPAKGEISEQESNCDIENSWSQPMYGDSTRFFKTSFPGIFQQDQGWNHEEYFTVQDLSASTAAAAAAAAAAATAGSTNAANGRSNKSFDFRLPLEATTSATANGSNSNSNQLQLFPQHGDTVLPSTSTNKKKRRRETHADKPTSTRIQPTATITSQQMLLHQPIQQQHHQHHHHQQHHLHNHLQQPSQQPVLHIQLQHQQQHHQQQNPSTSAALMAGPSTAAAAAAAAASGVATAMTIQQQKPRKKIFQCAHCSAKFPKLKDRNSHMIVVHNYVRQNRRLICTTNALAQATATATAADLMATSGAASSSSGIPHMMLDAQNGEFMEDSKQGIVKIEMDISPQPTSMAMSNENISTKSEFIDEKENMALIPVNGSTGVATVDAATAAAGTNAISNNQEDTKPTLQPLSVTTPATKLATLYRMLVSYNISTLKQSQTLTEVEEKLIETSIFFCYVCRNNFSSVKLYDAHLTEHPAECFTCGKKFQRWKNFSLHLKRHLGWKEFGCNVCDKKFVVRSALVEHMRMHTGQTPLKCKLCGKHFKRYSNLTQHRKRHGKMIVRKKEYVCHCGEVLPSKARFLWHKETHDAKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYTEPMECPMCKQIFAKSSIKAHMATHSMDTQHDCPICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVREVDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDLCKKSFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTVEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -