Mdol013607.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- grau
- Assembly
- GCA_963854835.1
- Location
- OY978527.1:5708354-5715900[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.29 28 6.3 0.3 2 23 342 364 341 364 0.95 2 9 0.0042 0.4 12.1 2.0 1 23 396 419 396 419 0.98 3 9 0.014 1.3 10.5 6.3 1 23 427 449 427 449 0.98 4 9 2.3e-05 0.0022 19.2 0.3 1 23 456 479 456 479 0.97 5 9 7.6e-06 0.00073 20.7 1.2 2 23 486 508 485 508 0.95 6 9 0.00095 0.091 14.1 2.8 2 23 517 538 517 538 0.98 7 9 0.0035 0.34 12.4 0.7 1 23 547 570 547 570 0.97 8 9 6.2e-06 0.00059 21.0 1.3 1 23 575 597 575 597 0.99 9 9 0.045 4.3 8.9 8.2 1 23 603 626 603 626 0.97
Sequence Information
- Coding Sequence
- ATGCTTTGTCGTTTGTGTTTAAGTGAATCACAggactatttatttatttttaatagtcATGACGGATCTTGTGATGGttcagaaatttcaaaaattattctcaaatattttcaaatggaaCTTCTTACAAGTGATGCAATTTCTAACATAATATGCCAAACGTGCTGGCATCAATTGTATGATTTTCATCAGTTTTGGTTGAATATTGTTCAAAAACAAGAGTTGATGCATCAACAGCAAGTAATTTTCAATTATGATGCACGACCGAAAATTGAAGAGGTACAAACAGATGATGATGTCAAGGCAATATCATTATATGAGCCACAAATCGATGCACTCGAGACAAAGGAAATTCCATTACTATCAGAATCGTCACAATCATGGGAAGATGAGCCGGATGTTTTAGCCGATCCATTGCCGGTAAAAACAACACGAACACCAATGAAGCGTCCTCAAAAAACTCGATATCACAATAAGAAAGCCTCCGAACAAAGAAAGTCTTGCCGTCTGATGGCAAAAAATGATGAAACAAACGATATATTGGTATCGCCAGCAATAGAACGTCTTCCGGAAGTGCAATTATTACATTCAGATGAAACTTTGGCAAGAAAGAACAATAATAGCCCACGAGAATCAAATCGTTCTAAACTGGATAAATCGAACGATGATACCGATGAAATGGCTGAACCTATGAATATTACAGCTTTATCCGATCAATGCAATGAAACGAAGCATGAAACCACTGATAGTGGTGCTAAAATGGTAAAGCTAAAGAGGAAAGTTGGACGTCCACCGAAGCTATCAAAGGAAAAAATGGAGTTTAAACCCATTAAGGAAAATAAATTGAGAAAACAAATAAAGCACAAAGAGAAAAGGCAAACAATTTTGGACGAGTCGACTGATGAGAGCTCACCGAAAAAAAATGCTTACGATAATAGACATTCGGATACCACTGTACTCTTGCCACATTTAATTTATACCATTAGTGAAATGGATGCTTATATTGCTGAACACTCACAATTACGGTGTAGCCTCTGTGAAGAACCATTGGCTAATTTTAATGTGTTGAAGAAACATTTTCGCAGCGTACACAAATTGAATGGTTATGCAATTTGTTGTCAAAATCGATTTCTTAAACGCACACTATTTGTTGATCATTTGAAAATGCACACTAATCCTGAATTCTTCAAATGCGCTCTTTGCAATAAGGTATTGGCTAATCGTAATTGCTTTTATAATCATATGGCAACATTACATCCACAAGATGAGGAACTCAAATTTCAATGTACACACTGCTCGCGCAAATTTACCAAGCAATACATATTGGATTATCACATGAAAAAACATCAGGAGGTGACAGGGGCATTTAACTGTAACATATGCCAGAAGGGATTTAAATCAGCTGTACTACTGAGTGTCCATCAGAAAAGCGTACACTTCAATAAATTTTCAGTGATGTGTGATTTATGCGGAAAAAGTTTCAAGaataagcaaaattttgtaaaacataaACAGTCAatacatgaaaatattcaagTACCAGAAGAACAATGTCAAATTTGTGGCAAATGGCTAAAggataaatataatttacataaacatatgtataagcaTCGTGATGAAGCTTCTGGCAAAGAATACGTATGCAACGAGTGTGGCATAGTGAAGACAACACGACAGAAATTGACAAGTCATATTAAATACAATCACGAGTACAAAACATATAAATGTACGCTGTGTGAAAAAGTGTGTAAGAGGCCTCGTGAATTACAGGAACATATTGCTACGCACACAGGAAAAGCTTTGTACAATTGTCAGTTTTGTACGCGTACATTTAAATCGCATGCCAATATGCACaatcataaaaagaaaatgcatCCAAATGAATGGATACGAAAATATTCGCGACCAACAAAACCGATAACTGTTACAAATCAAAACCCACAGCCGAGTTTGAgcattaatgaaaatttaattaatagcaTAGTTTAG
- Protein Sequence
- MLCRLCLSESQDYLFIFNSHDGSCDGSEISKIILKYFQMELLTSDAISNIICQTCWHQLYDFHQFWLNIVQKQELMHQQQVIFNYDARPKIEEVQTDDDVKAISLYEPQIDALETKEIPLLSESSQSWEDEPDVLADPLPVKTTRTPMKRPQKTRYHNKKASEQRKSCRLMAKNDETNDILVSPAIERLPEVQLLHSDETLARKNNNSPRESNRSKLDKSNDDTDEMAEPMNITALSDQCNETKHETTDSGAKMVKLKRKVGRPPKLSKEKMEFKPIKENKLRKQIKHKEKRQTILDESTDESSPKKNAYDNRHSDTTVLLPHLIYTISEMDAYIAEHSQLRCSLCEEPLANFNVLKKHFRSVHKLNGYAICCQNRFLKRTLFVDHLKMHTNPEFFKCALCNKVLANRNCFYNHMATLHPQDEELKFQCTHCSRKFTKQYILDYHMKKHQEVTGAFNCNICQKGFKSAVLLSVHQKSVHFNKFSVMCDLCGKSFKNKQNFVKHKQSIHENIQVPEEQCQICGKWLKDKYNLHKHMYKHRDEASGKEYVCNECGIVKTTRQKLTSHIKYNHEYKTYKCTLCEKVCKRPRELQEHIATHTGKALYNCQFCTRTFKSHANMHNHKKKMHPNEWIRKYSRPTKPITVTNQNPQPSLSINENLINSIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -