Mdol000095.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- grau
- Assembly
- GCA_963854835.1
- Location
- OY978525.1:1066243-1068022[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 1.5 1.4e+02 4.1 0.3 3 23 181 202 181 202 0.97 2 9 4.2e-06 0.0004 21.6 0.4 1 23 235 258 235 258 0.95 3 9 0.00018 0.017 16.4 2.2 1 20 266 285 266 288 0.94 4 9 0.0043 0.41 12.1 0.7 1 23 296 321 296 321 0.95 5 9 0.59 57 5.4 1.0 2 23 327 348 327 348 0.96 6 9 0.00031 0.03 15.7 0.2 2 23 357 380 356 380 0.96 7 9 0.00014 0.014 16.7 0.9 1 23 387 410 387 410 0.95 8 9 2.4e-05 0.0023 19.2 1.2 1 23 415 437 415 437 0.96 9 9 0.00085 0.081 14.3 4.1 1 23 443 466 443 466 0.98
Sequence Information
- Coding Sequence
- ATGATTTGCCGTGTTTGTCTTCACGAGGCTGAGTGTCCACTTAATATATTTGATGCAAACGGAGAGCAGCTTAACATTTCCCAAATCATTGAAACTCATTTATGGTTTAAAcCACTTCCAAAGGATTCCATGTCAACTGTTATTTGCCGACTGTGTTGGTTTAAAATTGatgaatttcacaaattttacaTATGTGCGAAACAAGCGCATCTAAATCTTGGTAAAACTTTAGATTCGCAAGCTGAATATGATGACAACAATAGCGATGAATTAGAAATTAAAGATGAAATGTGGCATGAGCCTGAATTAAGTAATCCTCTTTATGAGCCAGAAGTAATCTTAAAATCTGAAAAAGACGAAAATGAATGTATAAACCAAGAGCAGAATTGTTTAGATACAAgagaaaataaaacaaaggaTGTTCGGAGTATTAAAAagcttcaaaagaaaaaaacaaatcgtAAAGGACGCACAAATTCTAGTGCGGGAAAGAAGTCTCCATTGGATGATGACCTCATTaagaaatatatcaaaatgGGTTGCGATTTATGTACATTCGTTGGTGAGGACTTTGATGATATGAGAACCCATTTCAGAACTGGCCATGACGGCGTTAGACCATATGTAATGTGCTGCGGCCGTAAATTAAATAAACGCGTGTTTCTAGTGCAGCATGCTTACAAACACAAAGATCCGGAATACTACAAGTGTGTCGAATGCTCAAAAGTTTTCTCCGATGGCTATAATTTACGCTCACATATGTTAGCATCTCATGCACAAGAAGATGAACTGAAGTATCAATGTGATCAATGTCCCAAGAAATTTTCACGACTTCACCTACTTACACTACATAAGCCATCACATATACCACTGAATGAACGTAGTTTTATTTGCGAAAAATGCACACAGCCTAAGgcATTTGCAAGCCAGTATCTTCttcaaatacatattcatatgcaacACATTAAAGCAACCAATGTGTGTCATGTATGTGCAAAGGAGATACGTGACGATAAGGTTTTTAAGAAACATGTACGTCTACATTTTGAGGATAGTGGTCCTAGAGTTAAGTGTCCTCGGCCCGATTGTGATCAATGGCTTAAAGATGAAGATAATTTGAAACGACACATGCGTCGTCACGCTGATGAAGGCAAAACGTTCACTTGTGATACATGCGGGAAAACGACAAAAAATGGCCGATCTCTCAAAAGTCATATAAGCTATGCCCATTCAAAGGAAGTACATTCTTGTGGTGAATGTCAAAAAACATTCAAAAGTGCAATTACATTGAAGGAGCACATGGCACAACACACTGGCGAAACGTTGTACAAATGTCCGTTCTGTGTGCGGACGTTCAATTCAAACGCAAATATGCATtcacacaaaaagaaaatgcatCCAATGGAGTGGGATTTATGGCGTAAAACAAAGCGTGGTAGTTCGCAgagtataataaacaaataa
- Protein Sequence
- MICRVCLHEAECPLNIFDANGEQLNISQIIETHLWFKPLPKDSMSTVICRLCWFKIDEFHKFYICAKQAHLNLGKTLDSQAEYDDNNSDELEIKDEMWHEPELSNPLYEPEVILKSEKDENECINQEQNCLDTRENKTKDVRSIKKLQKKKTNRKGRTNSSAGKKSPLDDDLIKKYIKMGCDLCTFVGEDFDDMRTHFRTGHDGVRPYVMCCGRKLNKRVFLVQHAYKHKDPEYYKCVECSKVFSDGYNLRSHMLASHAQEDELKYQCDQCPKKFSRLHLLTLHKPSHIPLNERSFICEKCTQPKAFASQYLLQIHIHMQHIKATNVCHVCAKEIRDDKVFKKHVRLHFEDSGPRVKCPRPDCDQWLKDEDNLKRHMRRHADEGKTFTCDTCGKTTKNGRSLKSHISYAHSKEVHSCGECQKTFKSAITLKEHMAQHTGETLYKCPFCVRTFNSNANMHSHKKKMHPMEWDLWRKTKRGSSQSIINK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -