Basic Information

Insect: Megamerina dolium
Gene Symbol: erm
Assembly: GCA_963854835.1
Location: OY978529.1:63588882-63591146[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.7e-05 0.0026 19.0 0.8 1 20 381 400 381 403 0.93

2 6 1.4e-06 0.00014 23.0 1.6 1 23 409 431 409 431 0.97

3 6 1.1e-06 0.0001 23.5 3.5 1 23 437 459 437 459 0.98

4 6 1.3e-05 0.0013 20.0 3.2 1 23 465 487 465 487 0.98

5 6 0.0021 0.2 13.1 5.9 1 23 493 515 493 515 0.99

6 6 2.5e-05 0.0024 19.1 4.3 1 23 521 544 521 544 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.7e-05	0.0026	19.0	0.8	1	20	381	400	381	403	0.93
2	6	1.4e-06	0.00014	23.0	1.6	1	23	409	431	409	431	0.97
3	6	1.1e-06	0.0001	23.5	3.5	1	23	437	459	437	459	0.98
4	6	1.3e-05	0.0013	20.0	3.2	1	23	465	487	465	487	0.98
5	6	0.0021	0.2	13.1	5.9	1	23	493	515	493	515	0.99
6	6	2.5e-05	0.0024	19.1	4.3	1	23	521	544	521	544	0.98

Sequence Information

Coding Sequence: ATGCAACCCTGTAGTCCATCCGGTGTTATTGCCATGATGCCACCATCAAAGAGTCCTATTATGGAAACTGCTGCTGGTCAAGGAGCAGTCCATGTGAATAGTGAATCTCATAAGATAACCACAACTGCGATAACATCCCCATCAATACCGGTAGCTGCTTCACCAATTAATGAGGTCACAACGATGCCGCCGAATTtacaaacagcaacaacaacagccacagTAACAACTTCGACGCGCTCATGCCCACTGAAGTTCTCCATTGCAAAGATAATGGAACCCGATCATCAACGATTGCGTGATGTTTCAGCTGCTGATTCGGATCGTTCATCGAGTCCCATCGAAGTTACTACCAATGACGAAGATGATATTGAAGAACATATTGATTTGACTACAACGTCTACTGTCAATATCAATActaatactaacaacaacaataattatacgaCGACCAGCGTACAGAGTGTCGAGTCCATGGAGAATTACGATTCAGCATTTAAGAAATATGTACCGACGGCAAATGTGGCTGTCCAGCAATTTGTTAATCCACGCCATCAAGAGTTAATTTCACAATATCCATTCTTGTATTATGGTCCGAATCAGTTGATGTGCGCAGCGGCCCAATATGCCGCCCTTACAGCGGCCCAACAGCAATCCCTATTAGCCAGTACAGCAGCAGGTGCGGCCCATTTAAATTTGACAGCATCGTTAAGTACGTTGCACTCACAGTCGTTGCGTCGTCATTTGGGCACGCCTGGACATCATTTGGCGgcggctgctgctgcagctgctgccgcGCAAGCCCAAGTACAGCAGGCACATCATCAGGCCTTGGCCAATGCACATCCGCAATTGCAACAATCTCTGGAGAAGACATCGCCACCTAGTCGTGATCGCCGTGAGTCCGCTAAGGGCGCTAGTGGCCCCTATCATGGTCATAAGCGCAAGCATTCGCCGGCCGTTGCTGCTGCTTCAACAGCGACTACCGCTGCGGTTGCTGCTACTGTGACACCGACAAGACCTGCCGAACAACATCTGGTCACGTCCTCGCCACCAGATTCACAACGTGTGCCGCCACGTACGCCTACACCCAATTCGCTAGATGACAGTCCGGGATCTTCGGCTGGCAAGCAGAAAACCTTTTCCTGCCTAGAATGTGGTAAGGTATTTAACGCCCACTACAATCTCACCCGCCACATGCCCGTCCATACTGGGGCACGCCCATTCGTTTGTAAGGTGTGCGGTAAGGGGTTTCGGCAGGCCTCGACGCTGTGTCGTCACAAAATTATTCATACCGCTGAAAAACCGCACAAGTGCCAGACATGTGGTAAGGCATTTAATCGATCCTCCACACTGAATACACATACACGCATTCATGCCGGCTACAAACCGTTCGTGTGCGAGTACTGCGGCAAAGGTTTCCACCAGAAGGGCAACTATAAGAATCACAAGTTGACGCATAGCGGCGAGAAGGCGTATAAGTGTAGCATTTGCAATAAAGCATTTCACCAGGTCTATAATCTCACGtttcacatgcacacacacaacGACAAGAAACCATATACGTGTCGAGTGTGTGCGAAGGGGTTCTGTCGCAATTTCGACTTGAAAAAGCATATGCGTAAATTGCATGACCTGGGCAGTGGCTCCATGGAAGATGACACACCACATGGCCCAGAGCGTAGACGTGAGTACACGCGGCGCAGTGAGTCATCATCGCACAGCTATCACAGTCATAATCGCGCGAGACAGATGACTCCCGATTCATCAGTCGGAAGTCTTAGTCCGCCAATTAATGTTACAACACCGCCACTGTCGAGTGGTGGTGAGACGAGTAGTCCCGTCTGGCACAGCCCATATCCGACATTGAACTCGGGTCATCAGTGCGTAACTCCACAAGACTATGGCCATCATTTAATGTCACAACCACCTACCATTCATAACTCGATTACATCGGCTGAGTATTCGGCAAGTTCCGCGCTTATCCATTTAGCAACTTCAGCGTCTGCAACATCATCCACCTCATCGGGAGTAACATCGGGTGGTGCTTctgcggcagcagcagcagcagcggctgCGGCAGCGGCGGCGGCTCAAATGATTTCCAATacacatcaccatcaccatcagcatcaacagcagctTCACCATCATcctcaccaccaccaccaccatcatcatcatcctccgCATCATCAGCGGCTctcggcagcagcagcagtcacTGCTATGGAAAATGTGCCTTTCATTGCCAAAGTATTTTGA
Protein Sequence: MQPCSPSGVIAMMPPSKSPIMETAAGQGAVHVNSESHKITTTAITSPSIPVAASPINEVTTMPPNLQTATTTATVTTSTRSCPLKFSIAKIMEPDHQRLRDVSAADSDRSSSPIEVTTNDEDDIEEHIDLTTTSTVNINTNTNNNNNYTTTSVQSVESMENYDSAFKKYVPTANVAVQQFVNPRHQELISQYPFLYYGPNQLMCAAAQYAALTAAQQQSLLASTAAGAAHLNLTASLSTLHSQSLRRHLGTPGHHLAAAAAAAAAAQAQVQQAHHQALANAHPQLQQSLEKTSPPSRDRRESAKGASGPYHGHKRKHSPAVAAASTATTAAVAATVTPTRPAEQHLVTSSPPDSQRVPPRTPTPNSLDDSPGSSAGKQKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTAEKPHKCQTCGKAFNRSSTLNTHTRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCSICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHDLGSGSMEDDTPHGPERRREYTRRSESSSHSYHSHNRARQMTPDSSVGSLSPPINVTTPPLSSGGETSSPVWHSPYPTLNSGHQCVTPQDYGHHLMSQPPTIHNSITSAEYSASSALIHLATSASATSSTSSGVTSGGASAAAAAAAAAAAAAAQMISNTHHHHHQHQQQLHHHPHHHHHHHHHPPHHQRLSAAAAVTAMENVPFIAKVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -