Basic Information

Insect: Megamerina dolium
Gene Symbol: -
Assembly: GCA_963854835.1
Location: OY978526.1:92384939-92388286[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.44 42 5.8 0.1 2 23 211 232 210 232 0.96

2 14 0.0021 0.2 13.1 3.1 1 23 238 261 238 261 0.96

3 14 0.0039 0.37 12.2 3.2 1 23 270 293 270 293 0.94

4 14 0.016 1.6 10.3 2.5 1 23 297 320 297 320 0.93

5 14 0.00012 0.012 16.9 1.0 2 23 361 383 360 383 0.96

6 14 0.88 84 4.8 0.3 2 23 399 419 398 419 0.95

7 14 0.015 1.4 10.4 4.5 1 23 434 456 434 456 0.96

8 14 2e-05 0.0019 19.4 2.6 1 23 465 488 465 488 0.96

9 14 3.8e-05 0.0037 18.5 0.4 2 23 494 515 493 515 0.98

10 14 4.4e-07 4.2e-05 24.6 0.4 2 23 521 542 520 542 0.97

11 14 0.0086 0.82 11.1 2.3 1 23 548 570 548 570 0.97

12 14 0.02 1.9 10.0 3.6 1 23 575 597 575 597 0.95

13 14 0.19 19 6.9 1.6 1 23 602 626 602 626 0.96

14 14 0.91 87 4.8 1.2 1 23 691 715 691 715 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.44	42	5.8	0.1	2	23	211	232	210	232	0.96
2	14	0.0021	0.2	13.1	3.1	1	23	238	261	238	261	0.96
3	14	0.0039	0.37	12.2	3.2	1	23	270	293	270	293	0.94
4	14	0.016	1.6	10.3	2.5	1	23	297	320	297	320	0.93
5	14	0.00012	0.012	16.9	1.0	2	23	361	383	360	383	0.96
6	14	0.88	84	4.8	0.3	2	23	399	419	398	419	0.95
7	14	0.015	1.4	10.4	4.5	1	23	434	456	434	456	0.96
8	14	2e-05	0.0019	19.4	2.6	1	23	465	488	465	488	0.96
9	14	3.8e-05	0.0037	18.5	0.4	2	23	494	515	493	515	0.98
10	14	4.4e-07	4.2e-05	24.6	0.4	2	23	521	542	520	542	0.97
11	14	0.0086	0.82	11.1	2.3	1	23	548	570	548	570	0.97
12	14	0.02	1.9	10.0	3.6	1	23	575	597	575	597	0.95
13	14	0.19	19	6.9	1.6	1	23	602	626	602	626	0.96
14	14	0.91	87	4.8	1.2	1	23	691	715	691	715	0.92

Sequence Information

Coding Sequence: ATGGACATCCAGTGTCGCTGCTGTTTGAGTACCACAGCAACGGATTACATAGACATGTTCAGCTCAATGGACAGTTCCCATTCGTTTTTCGAGTGTTTTATACAATCCACGCAATTAGAGGGTACTATTGATGATGAGCTACCGAAAATGATGTGTCGCAGCTGTGCCCATGATTTACAAGTCGTATTCGATTTTATCCAAGTAGCACGTCAGGCAGATAATGTACTGCGTAACAAATTGGTGATCAAGTCAGAGTCTGTGAATTTAGAACATAATGAACAggtcgaagaagaagaagatataaGGCAGTTGGAAGTTGTGGAATGTTATAATGATGACGAAGAATGTATACTGGAGGGAATATTGGAGGATGATGAAACCATAGATGAGGAGCCAGATTGTGAAACGCAAATGGAATTGATGGAGTTTGAAGCCACAGAAGAAGTCTTAATGGACGATTCAATGGCAGAAACGGAATACTTGGATGATAAAGACAAACCACCTAAAGAAACAAGTGACGCCTTAGAGTACAATTCAGAGGCAGAGTTGGATGAAGACTATTTGGTAGAATATAATGAAGCAGATAAGGAGTCTGCGACTACAAACTCTAGTGATAATGGGACGAAATGGAAATGTGTAGAATGTAAACGTGTACTACGCGGTGATGTGTCCTATGAGGGTCACATGAATATACACAGAGATATACGTCCATATAAATGTCCACAATGCCAATATGCATTTCGTTGCAAATACGCTTTGGAGCGGCATGTGAACCAACGTCACAAAGAGAAGGTATTGACCAAACGTTTTCATTGCGAGCAATGTGACAAAGTGTTTCGATTGCAAACCCTGTTGGATCAACATCATCAAGAGGAACATGAAAcaTTGTTTAATTGTACGAAGTGCTCAAAGGAATTTGATTCGCTGTATATGTTTGATAAACATCAATACTATGTGCATTCAATCAGTGCATCCATACAATGCCCGCATTGCATTGACGTCCATATGACGGGTTCTAAACTAGCAGAACACTTTCGTCTTGAGCACCCAACAGAATATGTCAAGTATTTTCCAAATACTGTATGTCAATATTGTAAAAAGCAATTCGAAACAGCCAACGAATTTCGCTCACACCTAAATACAGTACATTCCGATAAGAGCGATGATGCTTTAGCTAAGAAAAGTGTTGCAGTGCAATGCGAAGTGTGTAAAAAGCAATTGCTGCGCCGGAATATCGAAAAACACATGGCAATACATCAGAAAAAAGAATGTCAATCAACTACACCAGTTCCACGAAAGTATCTATGTGCCTATTGtcCACGTGAGTGTAAAAGCCAAAAGTCATTGCATCAGCATGAGAAAATGCACGATGGAGAATCACCGGATGTGGTGTATATGTGTTCCGATTGTGATCGCACATATTCTACGCAGCATCTGCTGATGCAACATCGCAAACAGGCACATAAGGAACGCGACAACAAATGTCCCATATGCGGTAATGCGTTCAAGCTGAAGAATCAATTGGTGAATCATATGAAGCTGCATTTAGAGAAGAATATACAATGTCCCATGTGTGATAAGAAGTATGCAAGACAATTTGATTTGAATGTACACATGCGTAGTCATACGGGTGAGCTGCCCTTTGCATGTCATCTCTGTGAGAAACGTTTCGCTATCAAAGTTCGCCTGACATATCATCTGCAAAAGCATTATGGCATCAAGCATCGCTGTAAAGTATGCAGTGCCGAGTTTAACTCAAAACAAAAACTTAAGGCTCACTCGTACAAACACACTGGCATGCCATATCGTTGTGAAATGTGTGATGATCACGGTTTTGCCAATCGTGATGTATTTAAACGTCATTTGTTTCGTGTACATAATACCAGTATGACTGATGAGGCCTTGGTTGAGATGTTCCAACGCAATACGGGCAAAACAACGCGTATTCGTCAAATAGACGAGTTAGATACAACGACGTGGCATGGGGAAATTCAAGAGAGCGTATCACCGGAAGTGCAACATCATAAACAGGCGCATAAGGAGAGTGACAACAGTGACATTGGCATGTCATATCGTTGTGGGATGTGCAATGATCATGGTTTTGCCAATCGTGATGTGTTCAAACGTCATTTGTTTCTAGTACATAATACCAGTATGAGTGATGAGGCCTTGGCTGAGATGTTCCAACGTAATGCGACCAAAACCTCGTTGCAAAAATCTGAGGATCACACGGCTGAGGATATTGTTATTAAagcagaaattattcctaaataa
Protein Sequence: MDIQCRCCLSTTATDYIDMFSSMDSSHSFFECFIQSTQLEGTIDDELPKMMCRSCAHDLQVVFDFIQVARQADNVLRNKLVIKSESVNLEHNEQVEEEEDIRQLEVVECYNDDEECILEGILEDDETIDEEPDCETQMELMEFEATEEVLMDDSMAETEYLDDKDKPPKETSDALEYNSEAELDEDYLVEYNEADKESATTNSSDNGTKWKCVECKRVLRGDVSYEGHMNIHRDIRPYKCPQCQYAFRCKYALERHVNQRHKEKVLTKRFHCEQCDKVFRLQTLLDQHHQEEHETLFNCTKCSKEFDSLYMFDKHQYYVHSISASIQCPHCIDVHMTGSKLAEHFRLEHPTEYVKYFPNTVCQYCKKQFETANEFRSHLNTVHSDKSDDALAKKSVAVQCEVCKKQLLRRNIEKHMAIHQKKECQSTTPVPRKYLCAYCPRECKSQKSLHQHEKMHDGESPDVVYMCSDCDRTYSTQHLLMQHRKQAHKERDNKCPICGNAFKLKNQLVNHMKLHLEKNIQCPMCDKKYARQFDLNVHMRSHTGELPFACHLCEKRFAIKVRLTYHLQKHYGIKHRCKVCSAEFNSKQKLKAHSYKHTGMPYRCEMCDDHGFANRDVFKRHLFRVHNTSMTDEALVEMFQRNTGKTTRIRQIDELDTTTWHGEIQESVSPEVQHHKQAHKESDNSDIGMSYRCGMCNDHGFANRDVFKRHLFLVHNTSMSDEALAEMFQRNATKTSLQKSEDHTAEDIVIKAEIIPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -