Mdol023205.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978529.1:32845768-32849003[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.012 1.1 10.7 0.8 2 23 16 37 15 37 0.96 2 15 0.084 8 8.0 1.1 1 23 43 67 43 67 0.93 3 15 0.0041 0.4 12.1 0.1 1 22 75 96 75 96 0.95 4 15 9.5e-05 0.0091 17.3 3.7 1 23 104 127 104 127 0.95 5 15 0.0071 0.68 11.4 2.7 1 23 133 155 133 155 0.97 6 15 0.00048 0.046 15.1 2.6 1 23 161 183 161 183 0.95 7 15 0.73 70 5.1 0.3 2 23 598 620 597 620 0.95 8 15 0.22 21 6.7 1.2 1 23 644 666 644 666 0.88 9 15 0.15 14 7.3 4.2 1 23 674 698 674 699 0.95 10 15 0.22 21 6.7 5.5 2 23 703 724 702 725 0.94 11 15 0.0018 0.17 13.3 0.1 2 21 738 757 737 758 0.93 12 15 0.0022 0.21 13.0 0.4 1 23 766 788 766 788 0.97 13 15 1.4e-06 0.00014 23.0 2.4 1 23 794 817 794 817 0.98 14 15 9.4e-05 0.009 17.3 1.4 1 23 823 845 823 845 0.98 15 15 0.00023 0.022 16.1 2.1 1 23 851 873 851 873 0.95
Sequence Information
- Coding Sequence
- atgcaaGCGATGGTCCAAATCACCACAGATGGTGTTCCAAAGCTGCATTGTCCGATATGTAATAAGGCGTTGGTTTCCCTGAATGGTTATGTGAAGCACACAAAGAAACATGAGCCACCAGGGGGTTTTATGTGTCGCTATTGTGATGCTCGTTTTTGTACAGATGAGGAGGATTATCGAGAACATATTCGTGTCATACACAATGGTGTCGATCGTGAAATGTACATTTGTGATAAATGCGGTGCCGAATACAAGACATTAGAACCTTATAAGAGGCACATGGAGACGTTGTGCGGTACCGTTAAGCCTCATAAATGTGAACAATGTAAAATGTCGTTTGTCACCAAGTATAATCTGAAGCAGCATAAGGAATCAATACACACGGGCGAACGAAAATTTTGCTGCAGCTATTGTGGTAAGAATTTCTTACAAAAGGGACGTCTTATTGAACATGAACGTTCACATACCGGTGAGAAACCATACAAATGTGATGTATGCGGCAAATGTTTTGCTCATCGTGAGAGTATTGTGACACATTCATCTATTCATACTGGTATTCGTTTGGTCGAATGCAAATGCTGCCATTCATCGTTTTCCTGCTATTCCAATTTGATAAAACATCGACGTACGCGTCCAGATACCTGTGGTCTGCCTGAATATGATCCGCCCAGGAATCGTATTCGTTCACATCGATCAAGAATTCCAGCTACCTTAAATCCAACATCGGAAATAAAAGTATCAAGCTCAAATCGTATTATAACATCTGACGCAAAggaacataaaaaacaaaagatatcccgcgataaaaaagaaaatggcaTTGATATGCCCACAACGATACGGAGACGCGGTACTCGCAAATGTACTGAACCGGAAGGGAAACCCATacgaaaaaaacgaaaaaagaacaTTACGAGTGATGACAACTCCGACCGTTCAGATTCAGAAATTATATGTAAGCGAAAGACACGTAAGCGTCGTAAAGAGGTGTTGCCCAATACCAAACAATCAAATGCAGTTGCAACGCCAAAAGAAGAGCCGCATAATTTTGCTTTAAATAGTTCAGAATCTGAAGATTTTCCTGATTTCGATCCAATTGATAGCGAAGAAAGTCTCTCTTATGGTAATGATtctaaattgaatattaaacaGGAACATCAGACCGAAATAGAAGTACAAGCGGAAGCATTTAGCTCGTATAACGAATTTGAATATACCAATACCAGTGAATTTGTAGATGCTGCATTCAATATTAAGTCTGAAGATGATATGAACATATTTAGTGAGAAAGATAAGCTACTCGACTGCCTTCTCAATGATAAAAATGTAATGCCAGCCGTTAGGAAAAATACCACCGCAGCCACAGATTCGCGGGAGAAAGTGAAAACAGAAGATGCATCTATACTGGAAGAACCTGAAATGGTTATGTTTAAAGATGTAGGCGATGATACAGAATTTCGCGAAGAAGATATATTGGATGTTAGGGATGTTGCTGATATTGTGATCACAAAATGTAAAATCGTCCTTGAAGACATCGCTACACATTACCCAAAATTAAAAGATGATAAAACCATTACCATTGAGACAAATAATATGGATTCCTTGCTCCAGTCAACCGATGAGCAACCACCTCCGACGAATAATAAGATAACACGAAAACGCCGTAAACGGAAGATTGTCAATGATGGCGATGATGTAAAAAAGAAGAGCGCTCCGAACCGCATggcaaaaatttcacaaaaagaATTAAAGGAACGTTTAAAGATTAGCAAAAAGGAAGAGAATTCATGGTCTTGCCCGTATTGTATTAAAATCTATTATATGCGGAAGCCATTTGAAAATCATTTGCGCCAAGATCACGAACGAACGGCGGACGAGGTTAGGGAAACATTGAAATCGCAACAGGTGGTCGAACTCAACGATGAAGTATTCAAGTGTCACGTATGCGACAAGATCTATTTGATGGAAAAACGCCTTTTGGCTCATGTGAAATTACATGGTCCCGATGCAAATCTCACGTTCAAATGCCCTTGCTATTGCAATATCTATTTCGCCTCGAAAGACGAAGCCACTGCACATGCGCACAAAGATCATCATGATCTATTGTACTGCAATTTGTGTAAGAAATTTATGACTGGGCATGACAGCCTAAAAAGTCATATGAAAAATCATCATGTGGAAAAGAATCCACGTGTCAAGGAAAGAAATTTAGTGTGTGATAAATGTGGCAAAAAATTCGGTGGACGAACCGCACTTACAGATCATGTGCGTTCCGATTGCGGTCGTATGCCTTTATATGCGTGCAACATATGTGACAAACACCTTACTACCGCTGGTATACTGAAGACGCATATGTTGTTGCATAAGGACGAGACACCGTTTCAGTGTGACCAATGTGGGAAGACGTTCAAGGTGAAGGCACAATACAAAACGCACATCAAAACACGACACAGCGATTACAAACCCTTCAAATGCCATCTTTGTCCCAAGGAATATCCATATCGTGAAAGTTTGCTCACGCACATGACAGTACACACGGGGATCAAACGTTTCCTTTGCAATGGCTGCGGTAAACGATTCACTTGTGTTTCAAATCTACAAGCCCATCGTAAGGTGCATGCCGAAACATGTGGTATGCTGCCACTAAATGCAAAGGCCACACAATATATGGGGGTGCAAAAAGGCAATTTGTTGCTGGGTGCGAAACCAGAAGCAGGACTTGATTATATCGAAACGAATACACTTGTCGCAAGGGAAGTCATCGATCGTGATTTGCCAATGGCACAAGAGCTAAATTATCCAACGCAACCAGCTCTAGCTGCGCTAATGAATTGTACGCAACCAGTACCACCAGTGCGCTTGATGTCGCCAACACTAAAAATGCCACCTTTTGTTGATAATGCTGCTTACccttaa
- Protein Sequence
- MQAMVQITTDGVPKLHCPICNKALVSLNGYVKHTKKHEPPGGFMCRYCDARFCTDEEDYREHIRVIHNGVDREMYICDKCGAEYKTLEPYKRHMETLCGTVKPHKCEQCKMSFVTKYNLKQHKESIHTGERKFCCSYCGKNFLQKGRLIEHERSHTGEKPYKCDVCGKCFAHRESIVTHSSIHTGIRLVECKCCHSSFSCYSNLIKHRRTRPDTCGLPEYDPPRNRIRSHRSRIPATLNPTSEIKVSSSNRIITSDAKEHKKQKISRDKKENGIDMPTTIRRRGTRKCTEPEGKPIRKKRKKNITSDDNSDRSDSEIICKRKTRKRRKEVLPNTKQSNAVATPKEEPHNFALNSSESEDFPDFDPIDSEESLSYGNDSKLNIKQEHQTEIEVQAEAFSSYNEFEYTNTSEFVDAAFNIKSEDDMNIFSEKDKLLDCLLNDKNVMPAVRKNTTAATDSREKVKTEDASILEEPEMVMFKDVGDDTEFREEDILDVRDVADIVITKCKIVLEDIATHYPKLKDDKTITIETNNMDSLLQSTDEQPPPTNNKITRKRRKRKIVNDGDDVKKKSAPNRMAKISQKELKERLKISKKEENSWSCPYCIKIYYMRKPFENHLRQDHERTADEVRETLKSQQVVELNDEVFKCHVCDKIYLMEKRLLAHVKLHGPDANLTFKCPCYCNIYFASKDEATAHAHKDHHDLLYCNLCKKFMTGHDSLKSHMKNHHVEKNPRVKERNLVCDKCGKKFGGRTALTDHVRSDCGRMPLYACNICDKHLTTAGILKTHMLLHKDETPFQCDQCGKTFKVKAQYKTHIKTRHSDYKPFKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNGCGKRFTCVSNLQAHRKVHAETCGMLPLNAKATQYMGVQKGNLLLGAKPEAGLDYIETNTLVAREVIDRDLPMAQELNYPTQPALAALMNCTQPVPPVRLMSPTLKMPPFVDNAAYP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -