Basic Information

Insect: Megamerina dolium
Gene Symbol: E2f2
Assembly: GCA_963854835.1
Location: OY978525.1:8208638-8211431[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.5e-05 0.0072 17.6 0.2 2 23 425 447 424 447 0.94

2 8 0.0005 0.048 15.0 0.7 1 23 454 476 454 476 0.97

3 8 4.6e-05 0.0044 18.3 4.7 1 23 480 502 480 502 0.97

4 8 0.00026 0.025 15.9 1.5 1 23 510 532 510 532 0.94

5 8 1.6e-05 0.0015 19.7 0.4 1 23 537 559 537 559 0.98

6 8 1.8e-05 0.0017 19.6 0.2 1 23 565 588 565 588 0.95

7 8 1.4e-05 0.0014 19.9 3.8 1 23 592 615 592 615 0.97

8 8 0.0023 0.22 12.9 0.4 2 23 650 672 649 672 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.5e-05	0.0072	17.6	0.2	2	23	425	447	424	447	0.94
2	8	0.0005	0.048	15.0	0.7	1	23	454	476	454	476	0.97
3	8	4.6e-05	0.0044	18.3	4.7	1	23	480	502	480	502	0.97
4	8	0.00026	0.025	15.9	1.5	1	23	510	532	510	532	0.94
5	8	1.6e-05	0.0015	19.7	0.4	1	23	537	559	537	559	0.98
6	8	1.8e-05	0.0017	19.6	0.2	1	23	565	588	565	588	0.95
7	8	1.4e-05	0.0014	19.9	3.8	1	23	592	615	592	615	0.97
8	8	0.0023	0.22	12.9	0.4	2	23	650	672	649	672	0.92

Sequence Information

Coding Sequence: ATGGGTTCGGAAGACTTTAGCGATAACGAAACTTCGTCACCATTATTGCGTGAACCTCCATGGATTCAACCGGATAATAGACGTTCAAAGAAATTGATCGTTCTAACAAgacaatttatgaatttattaacaCATAATAATGGCAAAATAGATATTTTGAAGGCATGTGCTATTTTAAACGTTAATCGACGACGTATATATGATGTTATAAATGTTTTTGAAGGCTTGGGCCTTGTCGAAAAAAAGCATGCTATGTTACGATGGCGAGCTGAATCTCTTGATATAAAGCTTCCATTACCAGCATCACTCGATGATCACGATTTAGCAGCAGAACATCATAATGAAACGACGCAAGTAATTGATTCACATTCCACACATTTATTGGACAAAAAGAAAGCACGGAAATCAACACCTACCCAAAACGATGCAACTAAGTCATTGCAATGTGATGAAATATTTGACTATATAGGGGAATTTGATGAACAGCATCTAGAAATGACTGGCCATCGTACTATTGCTATTCAAACTACTTGCTTAGAAACACGAACTTGTGGTCTTATCGGTGTTTCAATGGATAATAATGAATTCACATTGAATTGCTATCAATGTTCAGAAGAAATTCCAATATCGGATTGGAAGAATTTTATTGAACATGTCAAGAGACAGCATCATCCTTTACAGCATGCTTATatgaattttgatgaatttgtGGTTCAGAGAGAAACTTTGAATGTATCGAACTGCAGTAATACTGAAATTGAAGTAAagaatgatataaatgaaaatagtaATCATGTTGAccatggtggtgatgatgaagatgatgatgtaGATGCGGTTAATGATGATCTTGAAGAAATCGAAAAACAATTGTTAAATCAAATTGATCCACATAGCTCTAGTGAAGACGATGAAGATGACACAAATATGGCCGATAAAAATTTGATACGTTTTGGCAAAACAGATAGTGCAATAGTTATAGATTTTCTAGATATGGTTAAAGAATATCCCATTCTATGGAATACGTACAAATCGGCAAAACGATATCGAACAACAGTTCAATCTATAGCACAACAATTGAACGAACGTTGGAATCTTTCATTGACTGTAGTGGGCATGATGAAATCTGTGAATCGTATTAAGATTTGGTATCGAAGGATTATGCGTAACAAGGAAGAGAAGATGAACTATAGAATTAAACATCCAGATTACTTTGAAAGAGTCTCACAATTTATACAACTGCCTGAGGGCACACAATCACTTGCAATTGTTGTGTGTTCGTATTGCGAAAGATCGTTCAAAGATGAAAATCTGCTGCAAGCTCATCAATATATAACACATAAAGTGGGCGAGCTTCCATATAAGTGCACAATGTGTGATAAACGTTTTATTAATGAAGCTCGCGTTAAGACGCACGAAGCAACGCACAATAAAATGCACTATTGCAAGAAATGTGGACGCAGTTATTATCGTGAACATGCCTTAAAAATCCATATGGAGACACACAAACCCAAAATGCCGCAAAGTTTTGAATGCGAAACGTGTGGTAAAAATTTCACAACGCGTGGTATGTATAAATTACATAAAGTATATCATGAGCCACCGAAATATAAATGCGACATCTGTCCAAAGTCTCTTTACACGCCGTTCATGCTTAAGGAACATATGAAGGCACATTTGAATGAGCGTGATTTTATTTGCGAAGAATGTGGTATGGCGTATGTGCGGCAAAAACAGTTAATGCGTCACAAACGTGCTGTTCACTATAAgatgtatgcatgtaaaataTGTGATAAACAATTCTCTACCGCGAATTGTTTGAATAAACACCTGAAACGTTTCCATTTAGTGTTGGAAGGTACCATTGAGCAATTGGAGGCAGCAAAACGTATGCGCAAAACAAAGCACACCTATATTACGGACCCCGTAACAAATAAGCGTCGCTTGGTATGTGAGATATGCGGTAAAAACTACAGTATGCATGAAGGTCTACGATCTCATAGTATAAAAGTGCATGGCATTAATCGGCTAAAGATTGCACCTCCAAAACGTAAACAAATTGATATGCACACAACTAATCAGTCGGCAGCAGTTTCTGACGATGAGTGTAATGAGGAGGCTCTTTATAGCGAAGTCGAAGTGGCCGAAGATAGCAATGAGTTGGCAACTACAGATGTAATTGCGAACAGTGAATATCTGGATGATTTTTCAGAATTAACACCTATTGAATATCTTATAGAAGAGGTTGATGATCCAATGGAAGATGAATAG
Protein Sequence: MGSEDFSDNETSSPLLREPPWIQPDNRRSKKLIVLTRQFMNLLTHNNGKIDILKACAILNVNRRRIYDVINVFEGLGLVEKKHAMLRWRAESLDIKLPLPASLDDHDLAAEHHNETTQVIDSHSTHLLDKKKARKSTPTQNDATKSLQCDEIFDYIGEFDEQHLEMTGHRTIAIQTTCLETRTCGLIGVSMDNNEFTLNCYQCSEEIPISDWKNFIEHVKRQHHPLQHAYMNFDEFVVQRETLNVSNCSNTEIEVKNDINENSNHVDHGGDDEDDDVDAVNDDLEEIEKQLLNQIDPHSSSEDDEDDTNMADKNLIRFGKTDSAIVIDFLDMVKEYPILWNTYKSAKRYRTTVQSIAQQLNERWNLSLTVVGMMKSVNRIKIWYRRIMRNKEEKMNYRIKHPDYFERVSQFIQLPEGTQSLAIVVCSYCERSFKDENLLQAHQYITHKVGELPYKCTMCDKRFINEARVKTHEATHNKMHYCKKCGRSYYREHALKIHMETHKPKMPQSFECETCGKNFTTRGMYKLHKVYHEPPKYKCDICPKSLYTPFMLKEHMKAHLNERDFICEECGMAYVRQKQLMRHKRAVHYKMYACKICDKQFSTANCLNKHLKRFHLVLEGTIEQLEAAKRMRKTKHTYITDPVTNKRRLVCEICGKNYSMHEGLRSHSIKVHGINRLKIAPPKRKQIDMHTTNQSAAVSDDECNEEALYSEVEVAEDSNELATTDVIANSEYLDDFSELTPIEYLIEEVDDPMEDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00966953;
90% Identity: iTF_00966953;
80% Identity: iTF_00966953;