Mdol020745.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978528.1:61151027-61153358[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.12 12 7.5 8.9 1 23 205 227 205 227 0.96 2 11 2.1e-05 0.002 19.4 0.6 1 23 233 255 233 255 0.98 3 11 0.00035 0.034 15.5 0.3 3 23 263 284 262 284 0.97 4 11 0.0057 0.55 11.7 4.6 1 21 290 310 290 312 0.95 5 11 0.00073 0.07 14.5 3.8 1 23 318 340 318 340 0.99 6 11 0.00033 0.031 15.6 1.2 1 23 346 368 346 368 0.98 7 11 0.0053 0.51 11.8 7.5 1 23 376 399 376 400 0.97 8 11 0.0029 0.28 12.6 0.7 2 23 406 427 405 427 0.97 9 11 0.0016 0.15 13.4 0.2 1 23 433 455 433 455 0.98 10 11 1.2e-05 0.0012 20.1 3.4 1 23 461 484 461 484 0.96 11 11 1.9e-06 0.00019 22.6 3.9 1 23 498 520 498 520 0.97
Sequence Information
- Coding Sequence
- ATGTCTTCGTCGGCATCAGCGGATAATCAAGATTTGCAAACCTATTTGGATTCATTTAACAAGGACATTGATGATGGCAGCGACACGCTTGTTACACTGAACGGCAACGCTATGCAAGTTTTGTCTCGATCAGAGAAAGTCgcacaaaaaatattaagttcGCGCGATGATGAAGTAGTTATCgaagatgacgatgatgacggaACATATTTTGTAGTCCAAAGTGGTAATTGCTATTATCAAGTATCTGGAGAGCAGGCATTGACTAATGTCGCAAATGAACCGAGTGCCACAACGAGTTCgcacaaaaaaatcataaaatctgaaatattgcaaaaaattaaaagagaagATTGTAAAGATGGAACTGACGAGGATATGGAATATGTTTTgattgttgaaaatagtgccacCAAGGATATGGAAGATACTAATGATGCTGATCCCGATGATCCAGGTGTTGCGCATAAGGAAATCTATGAATTTGATGAGAACGAGGAACTAGAAGCAGAGACAACTGCCCCACAGGAAAAAGAGTTACTTGTAACTAAAAACGTGGTACGATTGAAGTCAGTCAATGCAAGCAGTTCGGAAGCAGATGGTAGTGCTACCCACCATTGCACTCATTGTGATTATAAGACCACCAAGAAATTTCTGCTTTCGCGACATCTAAAGGCGCACTCAGACGAACGTCCGTTTATTTGTTCCGTGTGTGAGCGAGGCTTCAAGACCAACAATTCACTAATGAATCATGTAAATACCCATTTAGGCAATAAACCGCATGGATGTAAATTCTGTGAAATGGCATTTACAACCTCGGGTGAGCTCGTACGTCACGTACGCTATAGGCATACGGGCGAAAAGCCGCACAAGTGTTCAGAATGTGATTACTCTAGTGTCGAGTTGAGTAAATTACGACGCCATATGCGTTGCCATACGGGCGAGCGTCCATATCAGTGTCCCCATTGCACATATGCCTCGCAGGACACCTTCAAATTAAAGCGACACTTGCGTACGCACACTGGAGAAAAACCATATCAGTGTGATATTTGTTTATCTCGTTTCACACAGTCGAACTCGCTGAAGACACATCGTCTGATTCACAGTGTTGGCGATAAGCCTGTCTTCAAATGTCATCTATGCAGCACGACGTGTGGTCGCAAAACTGATCTTCGAATTCACATTAAAAAGTTACACCATTCTGATACACCTTTAGTGTGTAAGCGTTGTGGCAAAGAGTTACCCGATCGTTACACATACAAGGTACACTCGAAGACACACGAAGGAGAGAAATGTTATCGGTGTAAAATATGTCCCTATGCTTCAATCTCCATGCGTCAGTTGGATAATCATATGCTCATACATACGGGTGAAAAACCATTTGTATGTGAACATTGTAAAATGACATTCCGCCAACAACAACTGTTGAAACGACATATTAATTTGTACCATACGGCTGAGTATGTGCCACCGCAACCAAGAGAAAAGAATCACTCTTGCCCGAACTGCAAGCGTATGTTCACGCATAAAGGCAATCTGATGCGACACATGGAAATCCATGATCCACGATCGAATGTTGTGcaggaaaatttaaaattgaaacaaggACGTAAAACACGTTTGATACCACTTGATGGCATGCCAAATGTTTCAATACCCAATGAGGCGGAAGGTGAATATTCATCggatatgaaatatgaaataatcgaagccaatgataatgataatgatgatgaagagtTGGTTTTATCAAATGAGGTTACCGATGACATTTCTACAGATTATATGCCAATTTCTATAAAGAATGAGCCTAAACAACTAATATCGGTGGAAGTCGGCGATGAGCAGTATATGCTTGTGGAAGTGGTACAAAGTGACGACGAACGGGATGATGTTGATCAAAATGATGAagatgacgacgatgataataatgatgttgatgaggtGAACTGTATCACAGTTCAAAATAGTGATGAAACTCTAATacAAATACCCCTTGAATCCCAACACAAAGATGGTATAGGCAATTATTTTGGTTTTAAGGAGGATGTTGGCACAGGATATGTTGATTCGGATGCCAAGGAAACGATACAATTACTTCAAATTATTGATGAtgtgtaa
- Protein Sequence
- MSSSASADNQDLQTYLDSFNKDIDDGSDTLVTLNGNAMQVLSRSEKVAQKILSSRDDEVVIEDDDDDGTYFVVQSGNCYYQVSGEQALTNVANEPSATTSSHKKIIKSEILQKIKREDCKDGTDEDMEYVLIVENSATKDMEDTNDADPDDPGVAHKEIYEFDENEELEAETTAPQEKELLVTKNVVRLKSVNASSSEADGSATHHCTHCDYKTTKKFLLSRHLKAHSDERPFICSVCERGFKTNNSLMNHVNTHLGNKPHGCKFCEMAFTTSGELVRHVRYRHTGEKPHKCSECDYSSVELSKLRRHMRCHTGERPYQCPHCTYASQDTFKLKRHLRTHTGEKPYQCDICLSRFTQSNSLKTHRLIHSVGDKPVFKCHLCSTTCGRKTDLRIHIKKLHHSDTPLVCKRCGKELPDRYTYKVHSKTHEGEKCYRCKICPYASISMRQLDNHMLIHTGEKPFVCEHCKMTFRQQQLLKRHINLYHTAEYVPPQPREKNHSCPNCKRMFTHKGNLMRHMEIHDPRSNVVQENLKLKQGRKTRLIPLDGMPNVSIPNEAEGEYSSDMKYEIIEANDNDNDDEELVLSNEVTDDISTDYMPISIKNEPKQLISVEVGDEQYMLVEVVQSDDERDDVDQNDEDDDDDNNDVDEVNCITVQNSDETLIQIPLESQHKDGIGNYFGFKEDVGTGYVDSDAKETIQLLQIIDDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -