Mdol021799.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978529.1:7189312-7191368[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00013 0.013 16.8 2.1 1 23 5 27 5 27 0.96 2 12 2.3e-06 0.00022 22.4 3.2 1 23 33 56 33 56 0.96 3 12 0.00024 0.023 16.0 5.5 1 23 62 85 62 85 0.96 4 12 0.0003 0.028 15.7 1.7 1 23 94 117 94 117 0.96 5 12 0.00035 0.034 15.5 1.0 1 23 226 248 226 248 0.98 6 12 1.7e-05 0.0016 19.7 6.4 1 23 254 276 254 276 0.99 7 12 0.15 14 7.3 0.1 1 21 289 309 289 309 0.95 8 12 0.056 5.3 8.6 6.7 1 23 336 358 336 358 0.99 9 12 0.0024 0.23 12.9 6.3 3 23 444 464 443 464 0.97 10 12 3.6e-05 0.0034 18.6 3.4 1 23 474 497 474 497 0.97 11 12 4.1e-05 0.0039 18.5 0.3 2 23 509 530 508 530 0.97 12 12 0.0028 0.27 12.7 9.3 1 23 536 560 536 561 0.94
Sequence Information
- Coding Sequence
- atgcaGAGAAGATATGCATGCAgcatatgtactaaatattttactaaacCATGTTTATTAACACGTCATCAAGTGGTACATACCAAATCAAATGCATATGagtgtgaaatttgcaaaaaaaccTATAGTCAATTGTCATCACTACAACGCCATCAGATGCATTATCACAAAGGCATACGTAAACATACTTGTTGCAAATGCTCACATagCTTTGCTCAAAAGAGTAATCTTGTTGCACATATTAAGAATGCACATTCCACGGCGGCGAATATTCAAATGTATCCATGTGAACAATGCTCATGTTCATTTAATTCGCAAATATCCTTATCACGACATATAACAATAAGGCATCGTGCAACAAAAGGGTGGAccaatgacgatgacgacatATTAATAGAAGATCCCACAGAGTTTGCACAAAATGTTTTACAGCAATTGAGATATTTACAAAATGACATGGCTACTATAGATAAAGTGAACAACATGAGATGTGATAGTAATGAACAGCAGTTACAGCTTCAGGAGTCGCCTGTGTCCAAAGTAAAATCTTTGCAATTAACGGCTGTGGACGATTATACAACAGATTTGGCTACCATCTGTGATAGATTAAATCCCAAGGGTGAAATGGAATTTATTGTAGTACAATGCATTACAAGATCCGATCATCAAAGGTATTATGTTTGCGAATTTTGTGctaaagaatttataaaaacatatgatTTTATAAGacATCGACGTATACATACAAAACAATCACCATATAAATGTGAATATTGTCAACGTTCATTTCGAACAAAATCCAAATTGCATGAACATACTCAAAGgcatattttaaatgaacatGTGGGTATTTTAAGTGGCCAGCATGAATGTCCAATATGTCTGGAAATGTATGATTCCATACGACAGTTAGATTTGCATATGAAATGTAATACTGCAAAAGATAAGGAATTGGAAATGTTGACACCATTGCTTCCGGAACCTATTTGTGTGAAAAATCGCTCATTTAAATGTGCCTATTgtattaaacaatttaaaacacGTCAAAATTGTCGTAGCCATATGAAGACACATTTACGTCATTTATTACATACCAATAATGATTTACCACAAGCGTTAAATACTGTTCAaggtgatgatgttgatggcgATGCTGGTCAAAGACAAAAATGTCTCATTGCCATAAGTGATAATAATACAAATCAAGTGACTAAACTAATTGAAATGCCTCAAATATTACCGTCTACTAAAAGGCACCGAAGaaacaatatatgtaaaattactcATAATTCGGACACTCCATCCAGTAgtaacaaatatacaaatatttgccGACATTGCAACAAAAATTTTCGCAAACGTTGTGATCTACAACGTCATGCTCAAGTGCACGTGCCACCAGAGAAACGTTCACATTCATTCACTTGTGACTTTTGCAAAAAGAGTTTCACACTAAAATCGACCTTACATGAGCATATTCGATTGGTGCATGCAACAGATGGCAAAGATTGCAGTAAGAAAATTACATGTCAAGTATGTGATAAATCGTATGGGTCACGGAAAgctttaaatatacatttacgcTTACACACCGGACAACGACCATTTCAATGTTTGTACTGTGATAAATGTTTTCGCACATCTGGCCATCATATAGCACATATGCGTACAACAAAACATCATTAA
- Protein Sequence
- MQRRYACSICTKYFTKPCLLTRHQVVHTKSNAYECEICKKTYSQLSSLQRHQMHYHKGIRKHTCCKCSHSFAQKSNLVAHIKNAHSTAANIQMYPCEQCSCSFNSQISLSRHITIRHRATKGWTNDDDDILIEDPTEFAQNVLQQLRYLQNDMATIDKVNNMRCDSNEQQLQLQESPVSKVKSLQLTAVDDYTTDLATICDRLNPKGEMEFIVVQCITRSDHQRYYVCEFCAKEFIKTYDFIRHRRIHTKQSPYKCEYCQRSFRTKSKLHEHTQRHILNEHVGILSGQHECPICLEMYDSIRQLDLHMKCNTAKDKELEMLTPLLPEPICVKNRSFKCAYCIKQFKTRQNCRSHMKTHLRHLLHTNNDLPQALNTVQGDDVDGDAGQRQKCLIAISDNNTNQVTKLIEMPQILPSTKRHRRNNICKITHNSDTPSSSNKYTNICRHCNKNFRKRCDLQRHAQVHVPPEKRSHSFTCDFCKKSFTLKSTLHEHIRLVHATDGKDCSKKITCQVCDKSYGSRKALNIHLRLHTGQRPFQCLYCDKCFRTSGHHIAHMRTTKHH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -