Mdol012577.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978526.1:83309143-83312119[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0003 0.029 15.7 3.3 1 23 260 282 260 282 0.98 2 12 1.4e-05 0.0014 19.9 0.4 1 23 289 312 289 312 0.98 3 12 0.0001 0.0096 17.2 0.0 1 23 317 339 317 339 0.97 4 12 0.00019 0.018 16.3 3.9 1 23 345 368 345 368 0.97 5 12 0.00021 0.02 16.2 1.7 1 23 373 397 373 397 0.94 6 12 0.00036 0.034 15.5 0.8 1 23 402 425 402 425 0.98 7 12 0.11 10 7.7 5.3 1 23 555 578 555 578 0.97 8 12 2.1e-05 0.002 19.4 2.8 3 22 587 606 585 606 0.95 9 12 0.00043 0.041 15.2 2.6 1 23 615 637 615 637 0.97 10 12 0.0036 0.35 12.3 3.1 1 23 643 666 643 666 0.96 11 12 0.0021 0.2 13.1 2.2 1 23 671 695 671 695 0.92 12 12 3.1e-05 0.003 18.8 0.9 1 23 701 724 701 724 0.97
Sequence Information
- Coding Sequence
- atgagTTTCACCGAAATAGAAGATCTCTCAGAATATTGCCGAGTTTGTCTACAGCTGCCAGAACCTGATCAACTATTGgatctaaatttaatatacgATGAAGAGGAACAGTTGAGTTACAGCGATTGCTTTACGATATGCACACAAATTCAATTAGACGCTGAAGATAGAATGCCTCACAACTTATGCAAATCATGTGGCTTGGAATTGCAAATGGTCtatgattttcataaaaaaattgaagaatcgAAAAACTATTTGAAGCAGCTCGAAGAGCAAACCTATGAAAAAGATGAGGATGCAGAATCATTAACGGAGACTGAAAAGCATTTGCAGGAAGATACTTCCACACAAGCAGAAATTGTAACAGAAATAGAAGAATTAGATCCAAATATCGAATGTGATACAATAGAAGAACACTTGGATATGGAGGATGATTTCCAGACTCTTGAGGAGATTGATGAAAAAGATGTGGAAGCaatgcaaattaaaattgaagatTACGATATCATTGAAGATACGCGGACAAtacatgaaaattatgaaaataaaatgtatatgtatgaggcAACTGATAAATCTGAAGCAAATAATGATTTGTCATGGGAAGAAGCCGTCGTCACAGTGGCTAATAAATCCCATCTACCACTTGACGGATCTGTAAGCACAATAACGACTACAGAAAACGATCAGGAGCCCATTGATACCCTAGAGTCTCCCGCCAACGGTGAAGCAATAGGAACAATTGTTAGGGAACGTAAACGTCATACTGGAAAATATAGTTGTGACTATTGTcagaaaatatttccaaatcatTCACGTATGACTATACATCGACGTTCGCACGAACCGAATCGTCAGAAATATCCATGTACACATTGTGGACGGGTCTATGCGACCAAGCAGGCTATGCAGGTACATGCGCGCACCGTACACGTTAAAAAAGGGTTTGCATGCCCAATTTGTGATAAGATTTATGCTATAAAAAAAGGCTTAGAAGTGCATATACGTTATCATACGGGTGATTTTCCGTATGTCTGTGATTTGTGCGGCAAAAAGTTTGCACAAATGTGCCACCtcaatacacatacaaatgttaAACATAATAGCGTTCGTTTCTCCTGTGATCATCCGGATTGTGGTAAATATTTCACATCGTCCGCATCATTGAGAAATCACGAATTCTCACACAGCATTATGCCATTCGAATGTGAATTTTGTCAGCGTGGCTATCCAGCAAAATCCAAGTTAAAAGTGCATATACGGCGAAAACATGGTGTGGAAATGACTTTAGATGACTTGGAGAACATGCGAAAGTTTCATGTAATGCGCTCTAAATTGAATTTAGTTAAAGTAGCCGAAAAAGTGAACTTATGTAACAGCGGTGATGACAATTATAACGGTGATTTAGGATTTGATGATTTATATCAGCAGTTCTATGAAGACATTCCCAATGATGAAGATTCGAATGCTTATGACGATAAcaatgataatgttgatgatgatgatgatgctgatcaGAATGAGGACCAAAAATATatcatacaaattcataaagtcacacgaaaaaatgaaaaactctCAGTAGAGGTTCTGGAAAAGGTGGAGCCACAAAACGCACGAAAACGCACACGTGCTCCGACTGTAATCGGTGGGCCGCCCTACAAATGTGAACATTGTGAACACATCAGTCCTTCACGTTCATTGCTCGCGTCACATCGCCATCGCAAACATCGTCTAAAGGAGAATCGATTTGGCTGTCCGAAGTGTGACAAATGTTTCGATACACGCAAACAATTGGAACGGCACCAGAAGAGGCCCACATGCAATTCATATCCCGAATTCAATTGCGAGTATTGTGGCAAGAAATGCATTGGATTATCAAATTACAATATACATTTGCGCTTTCATAAAAAACTGTATCCGTTTGTGTGCCATCTGTGTGCCAAACGTTTCATGATGGCTACACATTTGAATACCCACATTAAGGCTAAGCATGAGAATCAACGATTCATTTGTGAACATCCAAATTGTGGTAAGATGTTTCAAACGCGCCACTCGCTGAAAATACACGCCTATGTGCATGTTGAGATGATGCCATATAAATGTGATTACTGTGATCGCATGTATCCCTCCAAGGGAAGATTACGATGGCACATAAGCAAGACACATGGCATTGAACATTCTCTAGATGAATTGGATAATATGATGGTGGCGGAAAAACTCTCAATAAAAGCTGAGATGCAACCAATTACtgttgaaaaaatttga
- Protein Sequence
- MSFTEIEDLSEYCRVCLQLPEPDQLLDLNLIYDEEEQLSYSDCFTICTQIQLDAEDRMPHNLCKSCGLELQMVYDFHKKIEESKNYLKQLEEQTYEKDEDAESLTETEKHLQEDTSTQAEIVTEIEELDPNIECDTIEEHLDMEDDFQTLEEIDEKDVEAMQIKIEDYDIIEDTRTIHENYENKMYMYEATDKSEANNDLSWEEAVVTVANKSHLPLDGSVSTITTTENDQEPIDTLESPANGEAIGTIVRERKRHTGKYSCDYCQKIFPNHSRMTIHRRSHEPNRQKYPCTHCGRVYATKQAMQVHARTVHVKKGFACPICDKIYAIKKGLEVHIRYHTGDFPYVCDLCGKKFAQMCHLNTHTNVKHNSVRFSCDHPDCGKYFTSSASLRNHEFSHSIMPFECEFCQRGYPAKSKLKVHIRRKHGVEMTLDDLENMRKFHVMRSKLNLVKVAEKVNLCNSGDDNYNGDLGFDDLYQQFYEDIPNDEDSNAYDDNNDNVDDDDDADQNEDQKYIIQIHKVTRKNEKLSVEVLEKVEPQNARKRTRAPTVIGGPPYKCEHCEHISPSRSLLASHRHRKHRLKENRFGCPKCDKCFDTRKQLERHQKRPTCNSYPEFNCEYCGKKCIGLSNYNIHLRFHKKLYPFVCHLCAKRFMMATHLNTHIKAKHENQRFICEHPNCGKMFQTRHSLKIHAYVHVEMMPYKCDYCDRMYPSKGRLRWHISKTHGIEHSLDELDNMMVAEKLSIKAEMQPITVEKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -