Mdol014112.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978527.1:14912359-14914533[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 6.3e-06 0.0006 21.0 0.2 1 22 216 237 216 237 0.97 2 11 0.00013 0.013 16.8 2.2 1 20 244 263 244 264 0.96 3 11 0.003 0.29 12.6 1.2 1 23 397 419 397 419 0.99 4 11 2e-06 0.00019 22.6 3.7 1 23 425 448 425 448 0.96 5 11 0.00036 0.035 15.5 0.4 3 23 457 480 455 480 0.93 6 11 4.3e-05 0.0041 18.4 0.3 2 23 489 510 488 510 0.97 7 11 0.00018 0.018 16.4 4.9 1 23 518 540 518 540 0.97 8 11 0.014 1.4 10.5 4.4 1 23 546 568 546 568 0.97 9 11 3.6e-05 0.0035 18.6 0.1 2 23 575 597 574 597 0.95 10 11 0.0014 0.13 13.6 3.9 1 23 603 625 603 625 0.97 11 11 6.1e-06 0.00058 21.1 3.9 1 23 631 653 631 653 0.98
Sequence Information
- Coding Sequence
- ATGAATAATATAACAAGTACGAATAGACATAATTTTTGTCGAACTTGCTTAAGTGAATTGCAAGGATACGGCTCCAACTTTACTATGAATAGCATGTACAATGTGCACGAATCTAAGGAACTTTCTCAGTGGGTTGTTAACTGCTTGCCAGTACCATCATTGGGTGAGAATGATTGTTTGCCAAATTTCGTTTGTACGGGATGCTATCAACAGTTGCAGTGTTTCTATGAGTTTCGTGAAATGTCTACTCGTTCAATGCGTACATTGTGGGAAATTCTTGGTTTATCCAAAAATGGAGAAGAAAACCAGACACTAGATTTGTTGGTGTCGTCAAATAATgtagatgaaatgaaatgtactACGACATTAACCAGTGAGCGAACAAAGGAGACTGTGAATCATGATGTGGATGATAAGAATCGGGTAATACAAACACTCCTGGAGAGTGTACGATTTGAACCAGAAAACAATATTGATGGACATGAATCACAATTTCCCCACGTCGATGCTATCATACCAGAAGTGCCAGTGCCAATCAACAATGAAGAAATGCTAGAAGACGCCATCGATACGCTTGACATCAGCAGCAACTATAACAACGcaaaaaaacaactgaaaaatCGATCACAACCCATTGCAAGTAAATTTCAATGTAAGGAGTGCAAACGAAGTTATGCCAATCAGGGGAACTTAGACGCCCATATACGAACCTGTCAGGGCCTTAAACCGTTTCAATGTAAGGATTGTGATAGCAACTTTAATAGAGCACATCACTTACGTCGTCATGTAGAATGTAGGCATTCGGAGAGTGTGCAGCAGAAAAACACTAAATTAAGCGAGGAGCCAGAAAAGAGCACGAAAACTATTACCAAAGAAAAGCTAAAAGCTACTCAGATCGATGGAAATGATGGTGCTGAGACAACATCGACAGATTCAAGAAAAGACAAGAGAagacaaattattacaaaagaaaaacagcGAAAACCTGTTGATGTACATTGTAATGATTCGAGTAATGATGGCGATGAAGATGATAAAGATTATAAAATCGATGATTCCGATGATTCGGAAGAATCGAATTACTCGGAAACCGAGAAGAAAACAAAACGGACGCCAAAAAGAACGAGGATAACAAGGAAAAAATCATCAGCGACATCATCGACAAATCCgattaagaaaaaatttatatataaatgcgaAGAGTGCAATCGGTATTACGCCAGCGAAGAGACACATGCCGCTCATATGCGCACCCATAAGGGTTTACCAGCATACTCATGTACAAAGTGCCCGAAAAGTTTTAAACGGTCATATCACTTGCGAATACACACGCTCAGCATTCACACTGAGAACGCAGAGCCAATTATTTGCAAAGTGGAAGGTTGTGGTAAATCATTTCGTATGGAAGTGTCCTATCGTAGACACTATCGTCTCCGACATACTGATGCAGCGCCCCAATTGAAAGTTTGTGAAGATTGTGGACGAGTTTTGAAGTCTGCCTCCTCACTGCGTGAACATCGCTATACGCATGCCCCACGCGAAGAGTATCCTTTTCACTGTGAGCAATGTGACAAACGTTTCTCATCACAGCGCACCTATAAAGAGCACCTGCTGCGACATGCGGGTATTAAACAATTCGTATGTCCACACTGTGGCATGCGTAAGACAACCCGCAGAGAATTGAAGACACACATCCATTATCATACGTTAGAAAAGCGGTGGTCATGTCCACTATGTCCAAGTGTCTTCAACCGTCCAGAAAATTTGACGAGACACAATCGCATTGTCCATATTGGACTGCGTGAGCATGTATGTCGTTATTGTAATGAGAGTTTCGCTAAACTCGAGACCTTGCGACATCATGAGATGCGGCATACGGGTGAAAAGCCCCACGAATGCCATATATGTCAAAAGCGATTCATACAATTGGTTGCACTGAAAACGCACATGAAAACCCATGCTAAATGTGGTATAACTCCAGAATTGCCACCACAACCACGTAAGCGACAGCGCCAATATCTAATGCAAGCACCACAACAACCAGAACAATTACAACCGGAAGAGGTACAACCGCAGGTACAACAATTTCAAAAAGACGGGAACCTTCTTGCAATGCCATAa
- Protein Sequence
- MNNITSTNRHNFCRTCLSELQGYGSNFTMNSMYNVHESKELSQWVVNCLPVPSLGENDCLPNFVCTGCYQQLQCFYEFREMSTRSMRTLWEILGLSKNGEENQTLDLLVSSNNVDEMKCTTTLTSERTKETVNHDVDDKNRVIQTLLESVRFEPENNIDGHESQFPHVDAIIPEVPVPINNEEMLEDAIDTLDISSNYNNAKKQLKNRSQPIASKFQCKECKRSYANQGNLDAHIRTCQGLKPFQCKDCDSNFNRAHHLRRHVECRHSESVQQKNTKLSEEPEKSTKTITKEKLKATQIDGNDGAETTSTDSRKDKRRQIITKEKQRKPVDVHCNDSSNDGDEDDKDYKIDDSDDSEESNYSETEKKTKRTPKRTRITRKKSSATSSTNPIKKKFIYKCEECNRYYASEETHAAHMRTHKGLPAYSCTKCPKSFKRSYHLRIHTLSIHTENAEPIICKVEGCGKSFRMEVSYRRHYRLRHTDAAPQLKVCEDCGRVLKSASSLREHRYTHAPREEYPFHCEQCDKRFSSQRTYKEHLLRHAGIKQFVCPHCGMRKTTRRELKTHIHYHTLEKRWSCPLCPSVFNRPENLTRHNRIVHIGLREHVCRYCNESFAKLETLRHHEMRHTGEKPHECHICQKRFIQLVALKTHMKTHAKCGITPELPPQPRKRQRQYLMQAPQQPEQLQPEEVQPQVQQFQKDGNLLAMP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -