Basic Information

Insect: Megamerina dolium
Gene Symbol: su(Hw)
Assembly: GCA_963854835.1
Location: OY978526.1:39528841-39531886[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00096 0.092 14.1 0.7 1 20 126 145 126 146 0.95

2 12 8.1e-06 0.00078 20.7 0.3 3 23 198 219 196 219 0.93

3 12 0.12 12 7.5 0.4 1 23 225 247 225 247 0.90

4 12 6.3e-07 6e-05 24.2 2.4 1 21 254 274 254 275 0.95

5 12 3e-05 0.0029 18.9 0.9 3 23 288 308 286 308 0.96

6 12 3.7e-05 0.0035 18.6 3.0 1 23 319 341 319 341 0.98

7 12 7.5e-06 0.00072 20.8 0.8 1 23 347 369 347 369 0.98

8 12 8e-06 0.00077 20.7 0.7 1 23 375 397 375 397 0.99

9 12 2.3e-06 0.00022 22.4 2.2 1 23 403 425 403 425 0.97

10 12 4.7e-05 0.0045 18.3 2.2 1 23 429 451 429 451 0.98

11 12 0.0022 0.21 13.0 0.5 1 23 463 487 463 487 0.91

12 12 0.11 10 7.7 0.6 2 23 501 523 500 523 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00096	0.092	14.1	0.7	1	20	126	145	126	146	0.95
2	12	8.1e-06	0.00078	20.7	0.3	3	23	198	219	196	219	0.93
3	12	0.12	12	7.5	0.4	1	23	225	247	225	247	0.90
4	12	6.3e-07	6e-05	24.2	2.4	1	21	254	274	254	275	0.95
5	12	3e-05	0.0029	18.9	0.9	3	23	288	308	286	308	0.96
6	12	3.7e-05	0.0035	18.6	3.0	1	23	319	341	319	341	0.98
7	12	7.5e-06	0.00072	20.8	0.8	1	23	347	369	347	369	0.98
8	12	8e-06	0.00077	20.7	0.7	1	23	375	397	375	397	0.99
9	12	2.3e-06	0.00022	22.4	2.2	1	23	403	425	403	425	0.97
10	12	4.7e-05	0.0045	18.3	2.2	1	23	429	451	429	451	0.98
11	12	0.0022	0.21	13.0	0.5	1	23	463	487	463	487	0.91
12	12	0.11	10	7.7	0.6	2	23	501	523	500	523	0.94

Sequence Information

Coding Sequence: ATGAATATCAAGCAAGAAAATGCCCGTCCGAGTAGTGGCATAAAAATACTGAATGACGATCGCATTCCAGCACTGCCACTACCAGTAATGACATCCGTACCACTTGCACCGTCTAAGCAAATAAGCATGTCAATTGCGAAAGCAAAAACATCGCCTACGAAGCAAAAACAAATGGATCATTATGTGTTGCAAACGACAAAAGTGGGTGATGGCGAGGAGGATGCCGAGAGTGAAACAATTGATTTCATTCTGACCGAAAACGATGGTGCCCAAGAGAATGATGGCCTTGGCGGGCCTAGTGGCGAAATTACGGAAGAATTGCACTTGAGTGGTGACGAGGAAGAGGGCGATGAAAAGACTGAGGAAATTGTCGAGCATGTATGTGGCAAGTGTTACAAGTCATTTCGACGTATCGGAGGTCTGAAGAAGCACTTGGATTTCTGTCGCTTTGATAGTGGATATCATTTACGTAAGGCTgagatgttgaaaaatttggagaaaattgAAAGGGATGCTATAAGCATGGAGAACAAAGATGTTTGCTTTTGCTGTGGTGAAAGTTATGATACGTTTCATTTGGGGCATATTAATTGTCCGGATTGTCCAAAATCGTTCAAAACACAAATCAGCTATGAACGTCATATCTTCATTACACATTCAGAGTTCGATGACCATCCGTGTACGATTTGTAATGCCAAACTACGAAGTGCTAATCTATTAAAGCTGCATGAGGGACAGCATCAAAATCGTGGAAAACCGTATGCATGTAAAATATGTGGCAAGGATTTTACACGATCATATCATCTGAAACGTCATCAAAAGTATTCATCTTGCTCGGCCAATGAAAACGATTCTATGAATTGTAAAGTCTGTAATAAGGTATATTTTCGTTTAGATAATTTGCGCGctcatttaaaaaatcatttggGAACAAATGTAACCAAGAAATCAGAATACATGTGTCCCATTTGCAAGAATTGTTTTTACAGTTTGTCCACATTGAACATTCATACACGTACCCACACCGGAGAGCGTCCATTTGAATGTGATTTATGTGATAAAAAATTTCCTTCTTTGGTCGCTTTGAAAAAGCATCGCCGTTATCATACTGGCGAAAAGCCATACACATGCTCAGTGTGTAATCAATCGTTTGCAGTGAAAGAGGTGCTGAATCGTCACATGAAGCGTCATACGGGGGAAAAACCTCATGTTTGTAAGGAATGTGGAAAAAGTTTTATACAGGCTACCCAATTGCGAAGTCATTCGAAAACGCATCTAAAACCTTATGAGTGCAATACGTGCAAAGAAAAGTTTAAAACTGAAAAACAGTTAGAGCGACACTCCAAAATACATAACAAGGGTCTCAAACGAAAAAATATTCAAGATTTTAATTGCAAAGTTTGTAGTGTTGCTTTCGGGAAAAAGGAACAGCTTGTTAAACACTTGAAGTCTGACAGTCACTCTAagcAACAGGAGAGGTACAATAAGAATGCACTCACATATTGCTCAATGTGCGAGAAGGATTTCGAAACCGTTAAAAGTCTGCAGTTTCATATTCTGAAAGTACATCAAGTTGATGTGGAAGAGTGTATTGATAACAACAAAGACGACGTATATAAAGTAGAAGAGTTGAACAATAGCTCAGGGCAGATACAATTTATTACTACGACCAGTGATGGCGATATGATCCTCAATGAGAGCAATAAATTAGAAAGTGAAACTCAAGCGACAAACACCATAAACAACGGCTTGGTAGTACAGGagtacattgtaaataataacaCAAATGACAATAAACAAAcgattattttgcaaaatgaagCATACACAATTATACCATTGGACTCTGATGGCATTATAGAAACGGTTACAACAAATACAATGCCCATGCAGGTGGACAAAGATATGAGAAAGGAACAAAGAAAATCGCTGGCTCAAAGCTTAGCTGCAGCTATTGCtgacgatgatggtgatgatgatgaatactCCAAAGTTATGGATATAGAAACTGAAGATGATatcaaattgaaagaaaatgtaCGAAAGTTACTGGATATGCTAGTGGATAATGTGACTTTGACCAAATTTGGATGGCCAAAGACATCGGAAGAAAATGTGCTGTGTAAAGTGATTGAAAATTGCGGTCATAATCTAAGTAATGATTCCGATTTATACAAATACTGTGACTATGCCACTCGCATGCgtgaatatgtaaaattattatttacggTCGTCATACATAATGATTCCATAAAGGAATTACTCAATAATTATCCAATAGATGAAGTCATTGAATATGTTCTGGgaagtgatgatgatgatgatgatggtgatgacgatgacgacgatatAGATGATAAGGAGTTGGTGGAGAAGAAGGAAGAGACATCAGAATCATTAGATAATGATGGCAATatcaataatgttgaaatagATACTTAA
Protein Sequence: MNIKQENARPSSGIKILNDDRIPALPLPVMTSVPLAPSKQISMSIAKAKTSPTKQKQMDHYVLQTTKVGDGEEDAESETIDFILTENDGAQENDGLGGPSGEITEELHLSGDEEEGDEKTEEIVEHVCGKCYKSFRRIGGLKKHLDFCRFDSGYHLRKAEMLKNLEKIERDAISMENKDVCFCCGESYDTFHLGHINCPDCPKSFKTQISYERHIFITHSEFDDHPCTICNAKLRSANLLKLHEGQHQNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDSMNCKVCNKVYFRLDNLRAHLKNHLGTNVTKKSEYMCPICKNCFYSLSTLNIHTRTHTGERPFECDLCDKKFPSLVALKKHRRYHTGEKPYTCSVCNQSFAVKEVLNRHMKRHTGEKPHVCKECGKSFIQATQLRSHSKTHLKPYECNTCKEKFKTEKQLERHSKIHNKGLKRKNIQDFNCKVCSVAFGKKEQLVKHLKSDSHSKQQERYNKNALTYCSMCEKDFETVKSLQFHILKVHQVDVEECIDNNKDDVYKVEELNNSSGQIQFITTTSDGDMILNESNKLESETQATNTINNGLVVQEYIVNNNTNDNKQTIILQNEAYTIIPLDSDGIIETVTTNTMPMQVDKDMRKEQRKSLAQSLAAAIADDDGDDDEYSKVMDIETEDDIKLKENVRKLLDMLVDNVTLTKFGWPKTSEENVLCKVIENCGHNLSNDSDLYKYCDYATRMREYVKLLFTVVIHNDSIKELLNNYPIDEVIEYVLGSDDDDDDGDDDDDDIDDKELVEKKEETSESLDNDGNINNVEIDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -