Mdol018087.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- Zfy1_1
- Assembly
- GCA_963854835.1
- Location
- OY978528.1:12278744-12282537[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 7.3e-05 0.007 17.6 0.6 1 23 148 170 148 170 0.97 2 11 1.1e-07 1.1e-05 26.5 1.7 1 23 176 199 176 199 0.98 3 11 1e-05 0.00097 20.4 0.7 1 23 205 227 205 227 0.98 4 11 3.4e-06 0.00033 21.8 2.5 1 23 233 255 233 256 0.95 5 11 5.2e-06 0.0005 21.3 0.3 3 23 265 285 263 285 0.98 6 11 0.024 2.3 9.8 3.3 1 23 291 314 291 314 0.96 7 11 0.044 4.3 8.9 0.2 1 23 320 341 320 341 0.96 8 11 5.5e-05 0.0053 18.0 2.6 1 23 347 369 347 369 0.97 9 11 1.6e-05 0.0015 19.8 1.9 1 23 375 397 375 397 0.99 10 11 0.0084 0.81 11.2 1.1 1 23 403 428 403 428 0.88 11 11 0.00016 0.016 16.6 0.1 1 21 434 454 434 455 0.95
Sequence Information
- Coding Sequence
- ATGGTGCGCAGTCGTCGTTCCATTTCGAAGGAAGACGCCTCATCTGTGGTGACTGATAGTGGCATATCATTATCGTCGCCACGATCTGCTGTCACTACCACCAATTATCAATTAGACGAGGATGAGGAAgaggctctcatacaaaagttatGTGTcaccgatgatgatgatactgatgTGGAgcaggaggaggaggaggaggaggagatCAGCAAAGATGTGACAGCATCAAAAAAGTCATCATCAAATCCAAAGAGGAAATGTAAATTAGATCCAGTGATTAAGacaccatcatcgtcatcatcatcatcatcattgtcgttatcgtcatcgtcattgaCATcaaaagtagcagcagcagcagcagcaacagcaccagcagcagtaaATGTACCACTGAAGAAGCAAGATCAACCACCATCGAAGAAACATCGTAAAAGTTACATTTGTCATGTGTGCCAAAAGGAGTTTGGTGGTAATACCGACCTCAAACGACATGTGCTCATCCATTCTGATGAACGACCATTTAAATGTGAACAATGCGGTAAATGCTATCGTCAGGctgtgaatttgaaaaatcacatGATCACCGCTCATGAGGGTCTCAAGCAGTACTCGTGCTCTGAGTGTCCAAAAACGTTTGCACTGAAAGAACGTTTACGTTTACATATGCGATTACATTCGGGCGAAAAGCCATACTCTTGTGAACACTGTGACAAATCTTTTGCTAGAGGTGGACAGCTCCAACAGCATATGGTTTCACATCATAATGATAGTTCAAGGAAATTTGGTTGTAAGAAATGTTCGGCTGCTTTTTCAACACCAGCAAATTTGCGTGCACACATGCAACGTCACGAAGATGGTCTTGATCATTATTGTTCAATTTGTAATCAACATTTCGGCAATAAGGTCATCTTGCGTACACACATCAACAAGGAGCATTACAAGTTGAAACAGTTCGACTGTGAGGTATGTAAGAAAACCATTGAGGATGATGATTTGGCAACGCACATGAAAACGCATGCTCACGTCAAAATGCACATTTGTGAAGTGTGTAATTCGTATTTTACCCAAAAGTCACAATATAATGTGCATATGCGTATGCACACAGGAGAAAGACCATACCAGTGTCGGatctGCTGGCAGACATTTGCACACTCGAGTGTATTAAAATTGCACATACGCAAGCATACGGGTGAAAAACCATTTAATTGTTTACTATGCAAAGATGAAGTTGCCTTCTCACAATTGGCACATCTCAAGACACATATGCgtaaaatacataaacaaaataatcCATATATGTGTGAGGGatgtaatgaattttttaagGTAAAAGTTGAATTGCAAGCGCACATGGAACAGTgtcccaacaacaacaacaacaacaacaacaacgacagcaatAGCAATACTAATGATAGTGGCAGTAGTAATTCTAATGATcagcagaagcagcaacagcaacagcagcagtcaAATTCACAAATTAGCGATATGGAAAAGTTGTCACATTTGCGTTTCCTTATTGCGTTGCTATTGAAGAAAATCTCCACAGAACAAAAGCTACGACAATTGGGCTATGAGAAACGTTTGATCGATAATGTTGTCATTGCATCATTGAAATTGGCAAACCGTAAGGCATACGATGATCACAAATTGTCTGCCATTGAACGAATGCGTTTGAATGTggaagaatttttaaattggaTTGTACCAGCAAAAATGATGCAAATTTTTCGTGAAGAGCAATTATCTGTAGAATGCATATTGGATAAAATTGTTTCGCTACATACAAAACAGAAatag
- Protein Sequence
- MVRSRRSISKEDASSVVTDSGISLSSPRSAVTTTNYQLDEDEEEALIQKLCVTDDDDTDVEQEEEEEEEISKDVTASKKSSSNPKRKCKLDPVIKTPSSSSSSSSLSLSSSSLTSKVAAAAAATAPAAVNVPLKKQDQPPSKKHRKSYICHVCQKEFGGNTDLKRHVLIHSDERPFKCEQCGKCYRQAVNLKNHMITAHEGLKQYSCSECPKTFALKERLRLHMRLHSGEKPYSCEHCDKSFARGGQLQQHMVSHHNDSSRKFGCKKCSAAFSTPANLRAHMQRHEDGLDHYCSICNQHFGNKVILRTHINKEHYKLKQFDCEVCKKTIEDDDLATHMKTHAHVKMHICEVCNSYFTQKSQYNVHMRMHTGERPYQCRICWQTFAHSSVLKLHIRKHTGEKPFNCLLCKDEVAFSQLAHLKTHMRKIHKQNNPYMCEGCNEFFKVKVELQAHMEQCPNNNNNNNNNDSNSNTNDSGSSNSNDQQKQQQQQQQSNSQISDMEKLSHLRFLIALLLKKISTEQKLRQLGYEKRLIDNVVIASLKLANRKAYDDHKLSAIERMRLNVEEFLNWIVPAKMMQIFREEQLSVECILDKIVSLHTKQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -