Basic Information

Insect: Megamerina dolium
Gene Symbol: hang
Assembly: GCA_963854835.1
Location: OY978527.1:46638187-46655741[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.078 7.5 8.1 1.3 3 23 346 367 345 367 0.93

2 19 1.6 1.6e+02 4.0 3.6 3 22 467 486 465 486 0.90

3 19 0.004 0.39 12.2 1.0 1 23 561 584 561 584 0.91

4 19 7.4 7.1e+02 1.9 0.1 2 21 596 615 596 616 0.88

5 19 0.011 1 10.8 0.4 3 23 704 725 703 725 0.96

6 19 7.7e-05 0.0074 17.6 0.1 1 23 733 756 733 756 0.96

7 19 5.8e-05 0.0055 18.0 0.1 2 23 844 865 843 865 0.97

8 19 0.059 5.7 8.5 2.9 2 23 922 944 921 944 0.94

9 19 0.0054 0.52 11.8 0.2 2 23 953 975 952 975 0.95

10 19 0.0003 0.029 15.7 0.2 1 23 988 1011 988 1011 0.98

11 19 0.00028 0.027 15.8 1.2 1 23 1063 1085 1063 1085 0.98

12 19 0.0026 0.25 12.8 0.9 1 23 1093 1116 1093 1116 0.96

13 19 0.014 1.4 10.4 0.1 2 20 1124 1142 1123 1142 0.95

14 19 2.1e-05 0.002 19.4 0.2 3 23 1227 1247 1226 1247 0.98

15 19 0.00018 0.017 16.4 0.7 1 23 1282 1304 1282 1304 0.97

16 19 0.00043 0.041 15.2 0.8 2 23 1361 1383 1360 1383 0.92

17 19 3.6 3.5e+02 2.9 0.1 2 19 1403 1420 1402 1422 0.90

18 19 0.077 7.4 8.1 0.7 3 23 1438 1458 1438 1458 0.98

19 19 0.00037 0.035 15.4 1.0 1 23 1741 1763 1741 1763 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.078	7.5	8.1	1.3	3	23	346	367	345	367	0.93
2	19	1.6	1.6e+02	4.0	3.6	3	22	467	486	465	486	0.90
3	19	0.004	0.39	12.2	1.0	1	23	561	584	561	584	0.91
4	19	7.4	7.1e+02	1.9	0.1	2	21	596	615	596	616	0.88
5	19	0.011	1	10.8	0.4	3	23	704	725	703	725	0.96
6	19	7.7e-05	0.0074	17.6	0.1	1	23	733	756	733	756	0.96
7	19	5.8e-05	0.0055	18.0	0.1	2	23	844	865	843	865	0.97
8	19	0.059	5.7	8.5	2.9	2	23	922	944	921	944	0.94
9	19	0.0054	0.52	11.8	0.2	2	23	953	975	952	975	0.95
10	19	0.0003	0.029	15.7	0.2	1	23	988	1011	988	1011	0.98
11	19	0.00028	0.027	15.8	1.2	1	23	1063	1085	1063	1085	0.98
12	19	0.0026	0.25	12.8	0.9	1	23	1093	1116	1093	1116	0.96
13	19	0.014	1.4	10.4	0.1	2	20	1124	1142	1123	1142	0.95
14	19	2.1e-05	0.002	19.4	0.2	3	23	1227	1247	1226	1247	0.98
15	19	0.00018	0.017	16.4	0.7	1	23	1282	1304	1282	1304	0.97
16	19	0.00043	0.041	15.2	0.8	2	23	1361	1383	1360	1383	0.92
17	19	3.6	3.5e+02	2.9	0.1	2	19	1403	1420	1402	1422	0.90
18	19	0.077	7.4	8.1	0.7	3	23	1438	1458	1438	1458	0.98
19	19	0.00037	0.035	15.4	1.0	1	23	1741	1763	1741	1763	0.98

Sequence Information

Coding Sequence: ATGTCGGAAGAGAGCTCTCTTCGAGCGCGACAAAATTGTTGTCGCCTGTGTCTAGCGCCGGATAGTGAATGTATATCTATTCTCAACAGCTATGCCGCGGACAAGGAGCCGTTGGCTACGAAAATTCATAACTGTGTTAACATTATGatttcCGCGAACGATCGACTTTCATTGCGAATATGTCATGCATGCATCAGCTATCTGAATTCGTGGCAAAGCTTCAAGAATCGTTGTATTGCTTCACAGAAAAAACAACGCAGTTGGCTGGATAGCagtaaacaacaacagcaacaattgctCGATAACAATGTCAGTATATCGGCGTTATCGTCGAGTGAgcgacaacagcaacagcaacaatcacAGCGAGATCATCATGATGACTTTGCAGCGGATCAAGGAAGTCTATCGTCATCCATACTTGATGGCATTACATCGTTGAAGAAGCGTAAATCATTAACAGTCTATGTGAGTCCAAAACAGCAGCAAAAACAGCTGCAAAGCATACAGCGACCAAAGTATTATAAGAAATTGTCCCATTATTATTACcaacattatcgtcatcatcatcaacaacaacaacaacaacaacaacaacatcaacatcatgaGCAACATCATGAACGACAACAtaaccaacagcaacaacagcagcgacAACAACAATCCTCTCAAAAACAGGATGATTGCAATGAAAGAcaccaaaaacaacagcaatacaCACAGTTGCAGTCTGTTGTTGCAACACCCGTCCAACATAGTGCTACACAGCAATTACGTTTATTTAGACGATATTCTTATAATCCGTTACCTGCCGTTGAAATAAAAGATGAACCACTTGATGCAGATGATGATTATTCAATGAAGCAGCATGATGAATCCGATGAAATGGTAGATCCAACCATGTTTTTGGAACGCACTGAGGAAGAAGGTGACATTCCACTCATGGATCACTCTACTAGCGGCTATGAATTTCAGCCAAATAATACAACCATAGCAATGACTACAATCGTTCCTGAAGTCAAAGAGGCATCATGTCGTGCgtgcaatttgaaattttcaacacGCGCTAATGCACGTCGTCATGAACGCAACTTACATCCCAATCTGTTTGAATTGTCCGCTTCGTCGTCCAATAATATGCTCATTACAAAACCCACAGCTGCATTGGAGATGCAACGagctgctgcagcagcagctgctgccgAAATGTCAAAGGTCTCAGCAGCAATATCATCGCAGAAATATCGTCAAGAAGTTATTAACGCGTTTAATAAGTGTGAAACAGGCGGCTATGACTATGACAATCCAGAGAAATATCAATATCTTCTCACCGATGAGAAAATTGTTTTCATCCAACAGAACGAGGAGTTTTTGCAGCAGTATCAGAATATGACATGTCGTTGTTGCAACAAATTCTACATGACCTATAAGAATTTTATGGCACATATGCGCAAGAAATATGCCACTTTGCCGCGTAATCTCTGTTTTAATTGCCTCAAACTGAACGATTCCAAAGCATTGTTTATATCACATTTGAAACGACGCAATTGTATTAATCTGTACAAGGTGTTGCACGCTCTGATGGCGAATAATGCCGATTTTGCAGAAGCTGTTACGGCGACTGCTGCAGCCGCACCCGAGAAGTTACGTGCCAAAGAGTTGCTGGTCAATAAGATGTACGAGTGTAAATTGTGTCCGAAGAGTTTCCGCCTAAAGCTCGAGTTTCGCACACACGTCTATGAAGATCACGCCGATGCGCAAAAGAAGGAGATCTCACCAAATCAATGCAGCTATTGTGGGTTAGATATGGAGGATCCTGCTGAGCGCAAACGTCACTATAACAATATGGATTGCATTGTGTTATTACGTTGTGTTACATGTGAGGCGAAATTCGACAAACATCAACAGTTTCTGGATCACGTTTACGATAAGCATTTGGCTGGATTTGGTGAACAAGTACAAAAAGTCGGTGGCAATACGGAGAATTCACCGGGAAAGAAAATATCAATTGGaaacACTTCCTCGGCTGATGAGTCACGTAGTAATCAAGGTGGTCAACAGTCACTTGCGCAAAAATCACAATACTCCTCACGTATGCCCCAGGCTTGCCGTATTTGTGgtcaacaatataataattataataatgtacTGCGGCACATGGAATCCAAGCATCCCGACCAATTGCCACAAACATACAAGTGTGTGAAATGTGGAATTGGCTATCCACGTCTATCGAATTTGCGTGAGCATATGGTGTCAGCACATGGTGCAGATAAGGCACGTCACACCGGCTTTGAATACATTGTGAATGCAAAGGCGGTTAAAATGGCCGATAATAATTCATCGAACACATCATCCGGACGTTATGATTATGTAATGAAGGATCTTATGTCCATTACCAATGGTGGATCAATTGcCGATGAGGATGGCGAAGGCGGCGATAATGTGGCCCCCAATGTTAAACGTATGCGTATGGACAATTCTTCAACACCTAACAACAATAACGCTATGTACGCAAATCTAAAAGAATGTCCTATTTGTAGTGCGGTGTTTAGTAATAATATTGGGTTGTCCAATCACATGCGTTCGCACACAGCAGCTGCTGCGGCATTGTCTGCTGCTAGAGGAACAACACCCAAATCGCTGTCAATAACCGCCACGTCAGGTGGAAATGCGATGGCGACAAATCAAACGCCTGCGGAGCAGGCTATTTTCAAACGCAGTCTCGAGCAAGCAGCCGACAGACGTTTTCGCCGTATGCGCTGCCGTATTTGCCAGCGTCGCTTCTCATCAAAGAAATCGTATCGTTTCCATATGCTGAATGATCATCAGATACGAAATGTTCAGTTCATTAAGTGTAAACTATGCGATGCGGAATTCGCCTATGAGAAGGGCTTGAAAGTTCACATGTTCAAGATTCATAATACCCTGCTAAAGGATGAAATGATTATTAAACAGTATGAGTGCGATATTTGTTCGATTGTTTACAGAACGGAAGAGCAATTGTTGCAGCACAAGAAGACCATTCATGCCAATGAAGAAGCACAGGCAGATGCTGAACTCGCTGAAACAAGTTCGGCAGGTGCGGATGCGTCCGGTATATCGACACCAGTGAGTGTTGTCGGTGCTAGCGCGGATCGCAGTTTATTGGATGGTTCCGGTGCTGGTGGTCAATTGTTGTGGTATCAGTGCAAATATTGTCCGTCCAATTTTAATACCAACAAAAAATTGGCCATTCATATTAAGCTACACGATGAGTTCGACTCGAACGATTATTCGTGTAAGGATTGTGGAAATGTATATAGTGGCCGAAAGAGTCTATGGGTTCATCGTTATAAGAAACATCCACAAATCGCAGAGCCATCCGAGTGTGAGCTGTGCAAGAAGGTCTTTTTCGACAGTCAAATGTTAGAAAGTCACATTCCGACATGTAATCGCAAACCGGTTAGCAGCTCGGGTGCCAATGCTGACGGCTCGGGCTTGCCGATTTACAAGCACAAaactggtgatgatgatgatgagttctCGCGTGACGATGAGGATGGAGGTGacggtggcggtggtggtggtgtcggTAGTCATGGTATACCAGCTGGCACTCTAGGCGGCGGTGAGGTGGAAATCACCGCGATTCCTGCAGCTGGCAATTTAAAAATCAAACTACCCGAAGTTGCTTGCACCATATGTGGACAACGTTTCACCGATCAAGAGCTGTTCGCAAAGCACATTCAAATGCATGAAATGGAATTGTATACGGACAATCCGCTAGCTGCTATGTTCGATACTGGTCCCGCCGATCCGAATCAGTTCTACTTGGATCGTGTCAATGATAATGGTGAATACGCGTGTGATTTGTGTTCAAAGACATTCACGCAAATGACTGCACTTAAAGTGCATCGAAAATGGCATTTCAGAGGTGATAGCAAACAGAACCCAGCCGAAATCGAGCCCACGCCATCAGCGACATTCTTACAGACCCAGATCAACCATCAACATCCGCTGGGATTACAAGCGGTAGGTCTTATGCCCAACCCTATGCGCACATCTTCAAAATCCCAGAAACGCAAACGCGAACTTAAATGCGAATATTGTACCTCAACATttataagcaacaacaacttgCGGCGTCACATATACGAGCTTCACAAGGACGAAATTTCCAATTTGCCTCAGCCACCGAAAATTGAGACTGACCAATATTTGAACTGCAGACGTTGCAATTTGAAGTTTGAGACAAAGGCGGAATGGGTAGAACATAAAGCAGCTGATGCCCGTATCACAAAGCCGTTTGGTCCATTCCAATGGGGTTGCGATCTGTGCGGAGCGTATGTGTCGCGCAAGGAGAAGTTAATTAATCATATACATAATCACATGAAAGAGAAGGTCATAGTTCCGGTGGAGGAACAAAAcaaggaacaacaacagcagcagcaacagaaacagcagcatcaacagcaacagcaacaacaacaacaccagcagcagcaacaaaagcCACAGGAAGTGTTGTTGCAACAGAAAAAATTACATTCAACATCATCATTGAATAGCTCTGAAAGTAATCAAAATCAGGAAGAGGATATATCGAATGATGAGGATGCTACTAAGGGGGAGTATGAGGAGGATGAAGCTGCGGCAGAAGTTGACGAAGAGGACGATGAGGAGGCCGAGGCAGAAgaagaggaggaggaggaggaggaggaagaTGTTGCAAGACATGCTGTTGTTCATGAGAATGAAAACGCAAACGATGGACAAAACGACGATGATGAACTTGGTGAAGCAAACAATTATAGtaagaatgatgatgatgatgaggatgatgatgatgatgatgatgacgacgacgacgacgatgatgatgatgaagatgaagagCGTGATGCTGACAGTACAACCGATTATGCAACGGTCAAGTCGAAGGTACCCACCAAAAAGACGACGGTAACAACGGCGGTTACAATGACCGCaccaacaaaaatttcaataaaaacttcACGACCTTCTGCTGACACTACGGAGGCCGAAGACTCACCGCCATATGCAGGTGAAGAAGATGACGATGACGAAGAAGAGGCCGACGATggtgatgacgacgatgatgatgacgatgatactGATGACGATGAGGACACAACTTCTTCAACGGATGGTCTCAagtcatcagcagcaacaacagcgaAAGCAAAAATACCAACAGTAGCTGTGAAGACGCGCTTTTCCTGTGACTTGTGTCAAGTATTCTTCGATACACAACAAGAGCTGCAGAAGCatgtaaaaatgcattttctcAATGGACCTGGATCGGTGTCGTTAACAGAAATTAAACCAAAATCTTCGTTAAATAAAAGTCGAAGCAGCAGCAGTGACATTGTTGCCGTATCGTCGTCGTAA
Protein Sequence: MSEESSLRARQNCCRLCLAPDSECISILNSYAADKEPLATKIHNCVNIMISANDRLSLRICHACISYLNSWQSFKNRCIASQKKQRSWLDSSKQQQQQLLDNNVSISALSSSERQQQQQQSQRDHHDDFAADQGSLSSSILDGITSLKKRKSLTVYVSPKQQQKQLQSIQRPKYYKKLSHYYYQHYRHHHQQQQQQQQQHQHHEQHHERQHNQQQQQQRQQQSSQKQDDCNERHQKQQQYTQLQSVVATPVQHSATQQLRLFRRYSYNPLPAVEIKDEPLDADDDYSMKQHDESDEMVDPTMFLERTEEEGDIPLMDHSTSGYEFQPNNTTIAMTTIVPEVKEASCRACNLKFSTRANARRHERNLHPNLFELSASSSNNMLITKPTAALEMQRAAAAAAAAEMSKVSAAISSQKYRQEVINAFNKCETGGYDYDNPEKYQYLLTDEKIVFIQQNEEFLQQYQNMTCRCCNKFYMTYKNFMAHMRKKYATLPRNLCFNCLKLNDSKALFISHLKRRNCINLYKVLHALMANNADFAEAVTATAAAAPEKLRAKELLVNKMYECKLCPKSFRLKLEFRTHVYEDHADAQKKEISPNQCSYCGLDMEDPAERKRHYNNMDCIVLLRCVTCEAKFDKHQQFLDHVYDKHLAGFGEQVQKVGGNTENSPGKKISIGNTSSADESRSNQGGQQSLAQKSQYSSRMPQACRICGQQYNNYNNVLRHMESKHPDQLPQTYKCVKCGIGYPRLSNLREHMVSAHGADKARHTGFEYIVNAKAVKMADNNSSNTSSGRYDYVMKDLMSITNGGSIADEDGEGGDNVAPNVKRMRMDNSSTPNNNNAMYANLKECPICSAVFSNNIGLSNHMRSHTAAAAALSAARGTTPKSLSITATSGGNAMATNQTPAEQAIFKRSLEQAADRRFRRMRCRICQRRFSSKKSYRFHMLNDHQIRNVQFIKCKLCDAEFAYEKGLKVHMFKIHNTLLKDEMIIKQYECDICSIVYRTEEQLLQHKKTIHANEEAQADAELAETSSAGADASGISTPVSVVGASADRSLLDGSGAGGQLLWYQCKYCPSNFNTNKKLAIHIKLHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQIAEPSECELCKKVFFDSQMLESHIPTCNRKPVSSSGANADGSGLPIYKHKTGDDDDEFSRDDEDGGDGGGGGGVGSHGIPAGTLGGGEVEITAIPAAGNLKIKLPEVACTICGQRFTDQELFAKHIQMHEMELYTDNPLAAMFDTGPADPNQFYLDRVNDNGEYACDLCSKTFTQMTALKVHRKWHFRGDSKQNPAEIEPTPSATFLQTQINHQHPLGLQAVGLMPNPMRTSSKSQKRKRELKCEYCTSTFISNNNLRRHIYELHKDEISNLPQPPKIETDQYLNCRRCNLKFETKAEWVEHKAADARITKPFGPFQWGCDLCGAYVSRKEKLINHIHNHMKEKVIVPVEEQNKEQQQQQQQKQQHQQQQQQQQHQQQQQKPQEVLLQQKKLHSTSSLNSSESNQNQEEDISNDEDATKGEYEEDEAAAEVDEEDDEEAEAEEEEEEEEEEDVARHAVVHENENANDGQNDDDELGEANNYSKNDDDDEDDDDDDDDDDDDDDDDEDEERDADSTTDYATVKSKVPTKKTTVTTAVTMTAPTKISIKTSRPSADTTEAEDSPPYAGEEDDDDEEEADDGDDDDDDDDDTDDDEDTTSSTDGLKSSAATTAKAKIPTVAVKTRFSCDLCQVFFDTQQELQKHVKMHFLNGPGSVSLTEIKPKSSLNKSRSSSSDIVAVSSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -