Basic Information

Insect: Megamerina dolium
Gene Symbol: -
Assembly: GCA_963854835.1
Location: OY978527.1:15059248-15061638[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.045 4.3 8.9 0.5 1 23 128 151 128 151 0.93

2 13 8.8e-05 0.0084 17.4 0.3 2 23 157 179 156 179 0.94

3 13 5.9e-05 0.0057 17.9 5.1 2 23 189 211 189 211 0.95

4 13 0.0012 0.12 13.8 0.8 1 20 369 388 369 390 0.95

5 13 0.0003 0.029 15.7 1.6 1 23 398 421 398 421 0.95

6 13 0.00014 0.014 16.8 1.2 2 23 424 446 423 446 0.96

7 13 7.8e-07 7.5e-05 23.9 1.7 1 23 451 473 451 473 0.98

8 13 0.00059 0.057 14.8 0.0 1 22 478 499 478 502 0.92

9 13 0.0022 0.21 13.0 1.3 3 23 508 528 507 528 0.99

10 13 0.00016 0.015 16.6 1.5 1 23 534 556 534 556 0.98

11 13 9.7e-07 9.3e-05 23.6 2.6 1 23 562 584 562 584 0.96

12 13 6.9e-06 0.00066 20.9 1.2 1 23 590 612 590 612 0.99

13 13 0.53 51 5.5 0.2 1 23 617 640 617 640 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.045	4.3	8.9	0.5	1	23	128	151	128	151	0.93
2	13	8.8e-05	0.0084	17.4	0.3	2	23	157	179	156	179	0.94
3	13	5.9e-05	0.0057	17.9	5.1	2	23	189	211	189	211	0.95
4	13	0.0012	0.12	13.8	0.8	1	20	369	388	369	390	0.95
5	13	0.0003	0.029	15.7	1.6	1	23	398	421	398	421	0.95
6	13	0.00014	0.014	16.8	1.2	2	23	424	446	423	446	0.96
7	13	7.8e-07	7.5e-05	23.9	1.7	1	23	451	473	451	473	0.98
8	13	0.00059	0.057	14.8	0.0	1	22	478	499	478	502	0.92
9	13	0.0022	0.21	13.0	1.3	3	23	508	528	507	528	0.99
10	13	0.00016	0.015	16.6	1.5	1	23	534	556	534	556	0.98
11	13	9.7e-07	9.3e-05	23.6	2.6	1	23	562	584	562	584	0.96
12	13	6.9e-06	0.00066	20.9	1.2	1	23	590	612	590	612	0.99
13	13	0.53	51	5.5	0.2	1	23	617	640	617	640	0.83

Sequence Information

Coding Sequence: ATGGATCTTCCAACTGTAAGATTAGAAACCAAATTGGATATGGAGAAGATTTGTCGCGCCTGTTTGCGTAGTGataaagaaatgtttttaatatatgATAAAAACTATGCAATTGGGCAGAAGACAATTGCCACAATGCTATcagaatttacaatttatactGTGGAACGTTTCGATCATTTGCCACATTTAATATGCAGTCTTTGCATGCATTCACTTAAAACGGCATATCGTTTCAAACATCAATGTGAGCAATCCTACAGGCATTTAATTGGACTACTTGATAATAGTAAGTCGCCCTGTCATACATCAATGAATGGAGTCAAATTGGAATTAGTGGATAATTTGGAGAAGAGTACGCAAACTGAAGATAGCACAATATATCCTTGTGAACGTTGTGAGTcgaaatttttcacattttatgcacTGCGGGCACATCGTGAGGAAGTCCATAAGGGTAGTGCGATTGTATGTCGATTTTGTGGAAAAACCTTTAATCGCATTGGTTATTTAAGAACTCATATTGCCATTTTCCATCCTGAATCCGGCTATAAATCACATAACGAATGTCACATTTGTAAACGACAATTTACGCGTAAAGAACATATGCGTCGTCATATGGCAATAACACATACAATAGCTGAACTTGTGGATGATgatgaggaggaggaggaggaagtTGCACAGGATCACAATGACAAATTGAATGTAGAACTGCATATAAAGAAATCATTTGTGGCAAATAATGATTGTTCCAAATCAAATGTAACATTAACCAGTGACAAAGTGAGAGTGatggaaaaaattgcaaatgataCCGATAATGATGATGCAGATGCTGGTGTTAATGgcgatgatcatgatgatgatgatgaaaagccGCTTATAAGTTTAATCAATAGAAATACGCccatcaatggatttattgaagTTCTCCTTAATGAAAGTACTTCAGAGgataaattcaatgaaaatgtgGAGCTGGCCCCTGAGAGTGTTGAACATGAGACTGAATGTGACGCTTTGCTTATATCCGATTTGGCTCCATTGAAGCGAAAACGTGGGCGGCCACGACGTAACAATGCGATATTACAGCAGCAGGAATTTAAATGCCAAAAATGTGATAAATTATTTCAACAGCAAACGATGTTACAAAGTCATGTGTCGTTATGTACCAATGATGTACCAAAGcataaatgtttaatttgtGCAAAGCACTTCCCATACAATGatgatttaaaattacatatgcAGGCTGTCCATAGGTTGGAATGCGATAAATGTGGTGAGGAGTTTGCACATGTTACAAAATTACGACGTCATCAGGAGACAAAGCATTCGAGAAAACGTTATACATGtgagaaatgtgaaaaaacgTTCACAACCAAAATCTATTTGCAACGTCATTTGCTGATACATGGCAAGTCAAAGTATACCTGCAAAGAATGCGCACAAATTTATGCCAGCAAAGAGGAGCTGCAGGCACATATCAAGGCAGAAGGTCACGACAAACCAATGTTGTGTCCCGAATGTGGGCTGCGTTGCAAAACGAGCAATATCTTAATGGTGCACATGCGACGGCACAATGGTGAGAAACCATTTAAGTGTAAATTTTGTAGTAAAGGGTTTCCCCGTATGGACGATTTACGTGTACATGAAAAATATCACACTGGTGAGAAATCCCACTTTTGTGAGACTTGCGGGAAAGGTTTCCAGCGTAAATATAATCTTACAATACATATGCGTGTACATACCGGCGAAAAACCCTATAAATGTCCACATTGCTCACAGGCATTTGCACAGGGCAATGATTTGAAGTCGCATATACGTCGCCATACTGGTGAACGATTTCGTTGTGAAGTCTGTGGTGCTGCATTCTTACAAGGCTATCAAATACGTCAGCATAAGCTAAATGAGCATGGCATCAAAGAAGAGCCACCAACACAACGTGTAGCAAAATTTACATCACCTGAGGAGCAAGCGCagcaaatcaaacaaaatttgcaaaagGAACTAACGAAAACCACATGCAGCGAGAATGTATGCATGGAGACAACGCATACTACAACAACAGTACCAGTAGCAGTAGCTATAGCAGACTTATCAAGCACAACGGCGTAA
Protein Sequence: MDLPTVRLETKLDMEKICRACLRSDKEMFLIYDKNYAIGQKTIATMLSEFTIYTVERFDHLPHLICSLCMHSLKTAYRFKHQCEQSYRHLIGLLDNSKSPCHTSMNGVKLELVDNLEKSTQTEDSTIYPCERCESKFFTFYALRAHREEVHKGSAIVCRFCGKTFNRIGYLRTHIAIFHPESGYKSHNECHICKRQFTRKEHMRRHMAITHTIAELVDDDEEEEEEVAQDHNDKLNVELHIKKSFVANNDCSKSNVTLTSDKVRVMEKIANDTDNDDADAGVNGDDHDDDDEKPLISLINRNTPINGFIEVLLNESTSEDKFNENVELAPESVEHETECDALLISDLAPLKRKRGRPRRNNAILQQQEFKCQKCDKLFQQQTMLQSHVSLCTNDVPKHKCLICAKHFPYNDDLKLHMQAVHRLECDKCGEEFAHVTKLRRHQETKHSRKRYTCEKCEKTFTTKIYLQRHLLIHGKSKYTCKECAQIYASKEELQAHIKAEGHDKPMLCPECGLRCKTSNILMVHMRRHNGEKPFKCKFCSKGFPRMDDLRVHEKYHTGEKSHFCETCGKGFQRKYNLTIHMRVHTGEKPYKCPHCSQAFAQGNDLKSHIRRHTGERFRCEVCGAAFLQGYQIRQHKLNEHGIKEEPPTQRVAKFTSPEEQAQQIKQNLQKELTKTTCSENVCMETTHTTTTVPVAVAIADLSSTTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -