Mdol014136.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978527.1:15053994-15057940[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 5.6 5.4e+02 2.3 1.8 2 19 111 128 110 133 0.86 2 14 1.9e-05 0.0019 19.5 2.7 2 23 151 173 151 173 0.97 3 14 1.3e-06 0.00013 23.1 3.3 2 23 303 324 303 324 0.98 4 14 2.7e-05 0.0025 19.0 5.4 3 23 332 353 330 353 0.94 5 14 0.015 1.4 10.4 10.4 3 23 521 541 520 541 0.98 6 14 2.3e-06 0.00022 22.4 4.0 1 23 547 570 547 570 0.93 7 14 0.00045 0.043 15.2 0.1 1 23 575 598 575 598 0.94 8 14 0.00013 0.012 16.9 2.4 1 23 606 628 606 628 0.95 9 14 0.00033 0.032 15.6 2.7 1 23 633 655 633 655 0.97 10 14 1e-05 0.00095 20.4 1.3 1 23 661 683 661 683 0.96 11 14 2.1e-05 0.002 19.4 0.7 1 23 689 711 689 711 0.98 12 14 1.8e-06 0.00017 22.8 1.7 3 23 719 739 718 739 0.99 13 14 2.5e-08 2.4e-06 28.6 1.5 1 23 745 767 745 767 0.99 14 14 2.1 2e+02 3.6 3.4 1 23 772 795 772 795 0.91
Sequence Information
- Coding Sequence
- ATGGATTTCGATAAAGAAATCTACAGAAGTCGTGTGTGCCGTGTGTGTTTAAAAGAAACACCGGAACTTTTTCCAATATTCGATAAGGCTTATGGATTGGAGGGTGCTGCCCGTCTTTCAGATGTACTTACTGAATGTACTCGATATCAAGTGCTCAGTAATGATAGATTACCACATAATATCTGTATTGCATGCATGGAGACAGCACGCGTATCATTTCAATTTAAACGGCAAACTGAGAATGCATATCGTACGCTGAAATTACTCCTAGAAGATATAAAAATACCTACTGAAACCGGGCCCATTGATAATTCGACACAAACGGCACAAACATGTAAATATTGTTCAGAAGAATTTTTGGAGAAAAATGAGTTGGAGGCACATTGTAAATTACAACATGCGGAACAATTTATCAAGGATTCAAATCCcataaatttaattgataagAGAACATGTCCAGTTTGCGATCGTCTTTTTTCGCGACGCGATCATATGCAACGGCATTTGCGTAAATTACATGGAATCGGATTAAAAAGcGCAAAAGATTCATTAGAAGAACCAGAAGTTGATTTAAAAACTGGTGGCGAGAATGCAGATATTGAAGGAAAATCGAGTGATGTTGGTGAGGGGGCTGTACAAATCGCAAACCCAATATCTATTAATGATGAAGAAAATGACGGCAATCAATTAAAACACGAAAACTTACTTTTGCATGATGCACCTATAAAAGATGAACCCATTGATGGAGACCATGCCACAAAGATGGACAATGATAGGAAACTGAATGATGATAAACCTATATCGAAAATGCGTCTGAACAGCACAGATGATAATGCCAAGGATGAAATGACTACTAAACGAACCATAGATATACGTCTTAAAGCGATTGCCCCGAATGAAGAAAATCGTTGTCCCGAATGCCAGCGTACATTCTCACGTTACCAGCACTTACGGCGTCACATGATGATTCATTACAATGAGAAGCCTCACCTTTGTCAACATTGCTCAAAGACTTTTTCACGTAGTGACCATTTAAAAGCGCACATTGCTAAAGCTCATCCAATACCGActgaagaaaaacaaagcagtaataatgattttgtaatatttgaGGTAGAAGAACAGGAGAATTTAGAAGTTGAGCCAGAGATTATCTTCATCGGTCTGAATGCTACTTCGACTGATGATGCTAATATtgaagatgatgataatgatcttAATAATGGTGTGGACAATTTGTTAGCTAATACTAATATCAAAGTTGAACCAGGTGAAGATTCGGACAATTCAAATGGTGATTGTGGTGGCGGTTATGGTGATGCCGGTGGCAACGATGTTTTTAGCGATAGTGACGATCATGTCCGCATAAAACGAATAAAACAGGAAAAGCGCACATCACCGAAAAGATATAAAGAAAGTGATACAGATTCAGAAGATGTTGATGTTAAGAAACTGATTCCGAAAAGTGAAAACGGAGCGGCAACGTCAGCAGCTCGACCGAATCAAGCGATCCGTCGTCGACGGCGTCGTGGTGAAGTACCGAAAACTGAAAATAATCATTGTCCAACATGTTTGCGTACATTTTCACGTCATTGCCATTTGCTGCGACACATGCTTACGCATCTAGACAACAAACCGCATACATGTCCCCACTGTCCGAAAAGTTTTGCTCGCAGTGATCATCTAAAGAAACATGTTGCCAATCTGCATGAGGTGAAGAAATTCAAATGTGAACAATGTCCCATTGCATTTGCATATCCCAAGGAATTGGTGCGTCACGTCGAACTAAGACATTCGGGTATCGATAATAAACTATATGATTGTGAATTTTGTGGTAAGAAATTTGCATCGAAAAATTATTTGAGCAAACACCGACTCTTTCATACGGATCGCGTATTCGCCTGTAAACATTGTGAGGAGACATTCAAAGAGCGTAAGCAATTGCGTGATCACGAAAAAGTGCATAATCTGCATCGCAAATTCTTATGTTCCATCTGTGGTGAGAGTTTTGAACGACACAACTATTTGGTAATCCATATGCGTCGACATAATGGCGAAAAGCCATATAAATGTCAATATTGTGGTAAAGGTTTTCCACGTGCAACTGATGTTAAAATGCATGAACGCTATCATACTGGCACCAAACCGAATCTGTGCACATTATGCGGCAAAGGTTTCCATCGTGCCTATAATCTTACCATTCATATGCGTACGCATACTGGTGAACGTCCATACAAATGCGATCAATGCGATAAAAGCTTTACACAGAGTAATGATCTGAAGGCACATATACGTCGTCATACTGGTGAACGTTTTCATTGCAGTAAATGTGATGCGgcatttttgcaattatattgTTTGCGTCAGCACTCGCTCAATGCACACGGCATTGTTATGGAAGCATCAAGTGGTCGCTTACAGAAATTTCCACCCGCACAACCAACGGCTACAGCAACGACTGGCTCATTAAATAGTAGTACAAACAATACAATTGCATCGAGCGTAGCATCGGTATCAGCTACCAGTTCAACAGCTAATATACCCGATATTATTAATAGCAGTGCGGAACAAGAATTACCTTCACCTTCCTCTGTTGTTCAAGCTTCTCATATTCCCGATATTCAAAgagagcagcagcaacaacatgagcaactacaacaacaacaacagcagcagcagcatcaacaccaccatcagcttctgcaacaacagcaacatatgCATGATCTTTCATTAATGCATAACGTCAACACTCCGTTAGCAAATACCGATTTAGTTGCAAAAGCTATGCAAACAATGATTgcaacatttcaacatttaggttag
- Protein Sequence
- MDFDKEIYRSRVCRVCLKETPELFPIFDKAYGLEGAARLSDVLTECTRYQVLSNDRLPHNICIACMETARVSFQFKRQTENAYRTLKLLLEDIKIPTETGPIDNSTQTAQTCKYCSEEFLEKNELEAHCKLQHAEQFIKDSNPINLIDKRTCPVCDRLFSRRDHMQRHLRKLHGIGLKSAKDSLEEPEVDLKTGGENADIEGKSSDVGEGAVQIANPISINDEENDGNQLKHENLLLHDAPIKDEPIDGDHATKMDNDRKLNDDKPISKMRLNSTDDNAKDEMTTKRTIDIRLKAIAPNEENRCPECQRTFSRYQHLRRHMMIHYNEKPHLCQHCSKTFSRSDHLKAHIAKAHPIPTEEKQSSNNDFVIFEVEEQENLEVEPEIIFIGLNATSTDDANIEDDDNDLNNGVDNLLANTNIKVEPGEDSDNSNGDCGGGYGDAGGNDVFSDSDDHVRIKRIKQEKRTSPKRYKESDTDSEDVDVKKLIPKSENGAATSAARPNQAIRRRRRRGEVPKTENNHCPTCLRTFSRHCHLLRHMLTHLDNKPHTCPHCPKSFARSDHLKKHVANLHEVKKFKCEQCPIAFAYPKELVRHVELRHSGIDNKLYDCEFCGKKFASKNYLSKHRLFHTDRVFACKHCEETFKERKQLRDHEKVHNLHRKFLCSICGESFERHNYLVIHMRRHNGEKPYKCQYCGKGFPRATDVKMHERYHTGTKPNLCTLCGKGFHRAYNLTIHMRTHTGERPYKCDQCDKSFTQSNDLKAHIRRHTGERFHCSKCDAAFLQLYCLRQHSLNAHGIVMEASSGRLQKFPPAQPTATATTGSLNSSTNNTIASSVASVSATSSTANIPDIINSSAEQELPSPSSVVQASHIPDIQREQQQQHEQLQQQQQQQQHQHHHQLLQQQQHMHDLSLMHNVNTPLANTDLVAKAMQTMIATFQHLG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -