Mdol023566.2
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- -
- Assembly
- GCA_963854835.1
- Location
- OY978529.1:40303563-40309358[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 2.9e-05 0.0028 18.9 3.1 2 23 226 248 225 248 0.96 2 19 0.0002 0.019 16.3 0.3 2 23 258 279 257 279 0.97 3 19 0.001 0.096 14.1 0.3 2 23 289 311 288 311 0.95 4 19 1e-05 0.00096 20.4 0.1 2 23 318 339 317 339 0.97 5 19 3.3e-05 0.0032 18.7 5.6 1 23 345 367 345 367 0.97 6 19 0.14 13 7.4 0.0 1 23 372 394 372 394 0.96 7 19 5.8e-05 0.0056 18.0 3.2 1 23 400 422 400 422 0.97 8 19 0.025 2.4 9.7 4.6 1 23 428 451 428 451 0.97 9 19 2.2e-05 0.0021 19.3 0.4 2 23 731 753 730 753 0.97 10 19 9.8e-05 0.0094 17.3 0.4 2 23 763 784 762 784 0.95 11 19 3.3e-05 0.0032 18.7 1.7 2 21 794 813 793 816 0.94 12 19 0.00053 0.051 14.9 0.0 2 23 823 844 822 844 0.97 13 19 0.0015 0.14 13.6 6.1 1 23 850 872 850 872 0.98 14 19 0.0016 0.15 13.4 0.1 1 23 877 899 877 899 0.97 15 19 9.2e-06 0.00088 20.5 2.7 1 23 905 927 905 927 0.98 16 19 0.027 2.6 9.6 5.5 1 23 933 956 933 956 0.97 17 19 0.0015 0.14 13.6 0.1 1 23 1006 1028 1006 1028 0.97 18 19 1.7e-05 0.0016 19.7 1.1 1 23 1034 1056 1034 1056 0.97 19 19 1.3 1.2e+02 4.3 3.3 1 23 1062 1085 1062 1085 0.80
Sequence Information
- Coding Sequence
- ATGGATTGGCAGTTATGGTGTCGTCTATGTGCAAAAAATGTTCCGGAAGGACATGCAACGCAGAGAACACATACGCTGGATGATATTAGGCGTACAATGAGAAAATACTTTAGGCTAAAGATTACCGATGAAGTGAAACTACCAAATATTTTGTGTGCGGAATGTTTTTCATTAGTAAAAACGCTTGTTGGGTTCGTAAAACATATTGCTAAAGTTCAGAAAATGTACCTCGATTTACAGGATAGCACCGATGGGGAGAGCTCTATATCGGATATGAATGCCATAcgtgtaaaatataaattacaagaTGGCCATAAAAAGCATATAATTGTACATTCACAGTTGCCAGAAGTACATGCTGAGGAAACGACAGAACAGGAATATGATTCTACTGCTGCAGTGGTGGAAACTCCTTTCGAAAGTGAAATACAGCTGGAAAATCGGGGCGATGATGCaaattttgaatatgatttAGATGTAGATAAATGTACCGTTGATGACACACATTTTAATGAGGTTGTTGTCAATGATTATGAAATTGTGACCATTATGGAAGACCCTGCAGATACACCTGATATAGAAGAAATGAGTAATTGCAGCAAAGAACAACCTAATCCTGGCAAAGTGCATCAACTGAGCGAGCAGGAATGCAGTGAAGAGAGTTCTAAAAGCATCTCTTGCCCGCAATGCCCACGTAAATTTAAACGGTCAACTAATCTCAGAATTCATTTGTGCAAAACACATCAAACAAAGCTGCCTGATCGCAAATGGTCATGCCCACAGTGTGCGTGGTCATTTGATGCAAAATACAAACTACAAAGGCACTTGAAAACTCATTTGccagatgaagaaaaaaatacactGCCGTGCCAATATTGTGGAAAAAAGTACAGCACGAAATTTATACTGCAAGCACATGTGCAAAGTGTTCATATGGATAAACGTCCAATCGTATGTGAAAAATGTGGTATATCAGTGCGAACAAATTCAGCTCTTAAATCACACATGTTAACGCATACAGATTATGCACCATTTGAATGTGAAGTTTGTGGCAAACACTTTAAAAATCAACATCGTTTAAAGGttcatatgaaatttcataACCCTGATAAATATACATGTGAAGAATGTGGTGTTCAAGTGAATTCGAGTTGGATTTTAAAAAAACATGCTTTGGTTCATTcggatgaaatgaaatttaaatgtgatttttgtgaGCGTCGTTTTAAGCGTCAGAAAACTTTACGTAATCATCTCATACTGCATACGGATCTTCAACCATATACATGCAATTTCTGTGATCGTACTTTTGCTAATGGCTCAAATTGTCGTAGTCATAAGAAGAGAGAGCATCCGAAAGAATTGGCAGAATATGAGGCAGCTGGGATACaaacttatacatataatattcccAAATTGGAACAacttataattatggCAAAAGCTGCAGCGGAAAATGGTACACGTAATAAGAATGGATCAGAGTCAGAATCAAATCTAAGCTATGGCATGGACTGTGAAGAGAGTAGTTCAGAACTTAATGTATCAACACACGACGAAGTTGTAATCGAATTGATTTTACAGATTACCGATGAAGCGAAACCACCAAATGTATTGTGTGTGGAATGTTTTTCATTAGTTAAGACGTTTCTTAAGTTTGCAAAACATGTTACAAAAGTGCAAAATATGTTTCTCACTTTACATAATAGTTGCAATGAGGGTAGTTCTTTATCGGATATGCAAGCTATACGCATAAAATATGGTCTACTGGAAggacataataaatatgtacttgaaCATTCACAGTTGCCGAATGAACACAATGAAGATATTACAtctgcaacaacaatagcagcagcagaaggagaagaagaagaagaagaagaatatgttACGGATGAACCAGTTCTTGAAAATCCTTtagaaataaaaacagaaaatacaaTGGACTATGCACTGGTTGACGGTAACATGGAAAATAGCtgcaacgatgatgatgaacagACTATAGATGATGATGAGGAGGATATTAAATACGAGTATGAAGTTGTGACGCCTGCGAAAGATGATTCAGACACTGATTCGGATAGCGAACAAGTTAGTAATGACAGCGTGGAAGAGGAAAGTAAAACTTGGAAAAGACGAAAACGCGAAAAAGTGGAGTGCACCGAAAATGGTGCTAAGAAAATTAAATGTCCAAAGTGCCCACGGGAATTTAAACGTTTAAACGATTTAGGTATTCATATGCGGAGAACACATCGATCAAAGCTGCCAAACCAAGAATGGCCATGCCCACATTGTACGCGCGTTTTCGATGCAAATTACAAACTACAGAGGCATATGGTCATTCATTTGCCCAATGAAGTTAGAAATATAGTGCCTTGTCCATATTGTGAAAAGAAGTTTAGTACGAAATACCTTCTACGAACCCATATCAAATGTGTTCATATCGATGAGCGTCCAGTCGTGTGTGAGAAATGTGGTGTATCGGTGCGAACGGTGGCCGCTCTTAAATCTCACATGTTGACGCATACAGATTATGCGCCCTTTCAATGTGACACTTGtggaaaatactttaaaaatgaatatCGTTTAAAGAATCATAAGAAGCATCATGATCCCCAGAAATATACTTGTGATGAATGTGGTATACAAGTGAATTCGCGTGTTAGTTTAAAAAATCATGCATTGGTCCATTCggatgaaatgaaatataaatgtgACTATTGTGAGCGTCGTTTCAAGCGTAAACTTAATTTACGAAATCATCTTTTGCTGCACACGGATCTTCAGCCATATTCATGTAATTTCTGTGATCGCACTTTTAGTAATGGTTCCAATTGTCGTAGCCATAAGAAGAAAGAGCATCCAAAAGAATTGGCCGAGTTGGAAGCAGCTGGCATACAAATCTATACGCATGATATTCCAAAATTGGATGAACTAACAATTATGGTTAAGGCTGCAGCTGCAAACGCAAAGCCAGAGCGACAATTAAACCAACTTGAAAATGGTAAATTTAAATGTGATGAATGTGGTATAGAAGTGAATTCGCGCAATGGCCTAAAAAAGCATGCAATCGTTCATACGGGTGAAAAGAAGTTCAAATGTGATTATTGTGGCAGTGCTTTTAAGCGTTCAACTACATTGCGAAATCATCTTATATTGCATACGGATCTTCGACCATATTCATGCGATTTTTGTGATCGTACATTTGCTAATGGTACAACATGTCGAGGTCATAAAAAGAAAGCACATCCCAAAGAATTGGCCGAACTCGAGGCAGCCGGTTTTCAAACCTTTACATATAATGTTCCAAAATTGAAGGACCTCAAGGTTATGGTAAAAGCCGCTGCCGAAATGGTAGGGGACATCAAGGAACAACCAGCAGAGAcagaattaaatataaaagaagaTAATATGGACAATGAAGAAAATAgtttataa
- Protein Sequence
- MDWQLWCRLCAKNVPEGHATQRTHTLDDIRRTMRKYFRLKITDEVKLPNILCAECFSLVKTLVGFVKHIAKVQKMYLDLQDSTDGESSISDMNAIRVKYKLQDGHKKHIIVHSQLPEVHAEETTEQEYDSTAAVVETPFESEIQLENRGDDANFEYDLDVDKCTVDDTHFNEVVVNDYEIVTIMEDPADTPDIEEMSNCSKEQPNPGKVHQLSEQECSEESSKSISCPQCPRKFKRSTNLRIHLCKTHQTKLPDRKWSCPQCAWSFDAKYKLQRHLKTHLPDEEKNTLPCQYCGKKYSTKFILQAHVQSVHMDKRPIVCEKCGISVRTNSALKSHMLTHTDYAPFECEVCGKHFKNQHRLKVHMKFHNPDKYTCEECGVQVNSSWILKKHALVHSDEMKFKCDFCERRFKRQKTLRNHLILHTDLQPYTCNFCDRTFANGSNCRSHKKREHPKELAEYEAAGIQTYTYNIPKLEQLIIMAKAAAENGTRNKNGSESESNLSYGMDCEESSSELNVSTHDEVVIELILQITDEAKPPNVLCVECFSLVKTFLKFAKHVTKVQNMFLTLHNSCNEGSSLSDMQAIRIKYGLLEGHNKYVLEHSQLPNEHNEDITSATTIAAAEGEEEEEEEYVTDEPVLENPLEIKTENTMDYALVDGNMENSCNDDDEQTIDDDEEDIKYEYEVVTPAKDDSDTDSDSEQVSNDSVEEESKTWKRRKREKVECTENGAKKIKCPKCPREFKRLNDLGIHMRRTHRSKLPNQEWPCPHCTRVFDANYKLQRHMVIHLPNEVRNIVPCPYCEKKFSTKYLLRTHIKCVHIDERPVVCEKCGVSVRTVAALKSHMLTHTDYAPFQCDTCGKYFKNEYRLKNHKKHHDPQKYTCDECGIQVNSRVSLKNHALVHSDEMKYKCDYCERRFKRKLNLRNHLLLHTDLQPYSCNFCDRTFSNGSNCRSHKKKEHPKELAELEAAGIQIYTHDIPKLDELTIMVKAAAANAKPERQLNQLENGKFKCDECGIEVNSRNGLKKHAIVHTGEKKFKCDYCGSAFKRSTTLRNHLILHTDLRPYSCDFCDRTFANGTTCRGHKKKAHPKELAELEAAGFQTFTYNVPKLKDLKVMVKAAAEMVGDIKEQPAETELNIKEDNMDNEENSL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -