Mdol006760.1
Basic Information
- Insect
- Megamerina dolium
- Gene Symbol
- grau
- Assembly
- GCA_963854835.1
- Location
- OY978525.1:98217009-98237870[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 35 0.053 5.1 8.6 0.6 2 23 250 272 249 272 0.94 2 35 2.6 2.5e+02 3.4 1.5 6 23 281 298 281 298 0.97 3 35 0.0013 0.12 13.8 0.7 1 23 304 326 304 326 0.99 4 35 0.0054 0.52 11.8 1.7 1 23 334 356 334 356 0.98 5 35 0.00016 0.016 16.6 2.8 2 23 365 387 364 387 0.96 6 35 0.00054 0.052 14.9 0.4 3 23 395 415 393 415 0.94 7 35 0.002 0.19 13.2 1.6 1 23 423 446 423 446 0.97 8 35 2.5 2.4e+02 3.4 0.6 2 12 455 465 454 477 0.79 9 35 0.0018 0.18 13.2 4.1 1 23 483 505 483 505 0.96 10 35 1.3e-05 0.0013 20.0 1.3 1 23 511 534 511 534 0.98 11 35 0.14 14 7.3 0.4 2 23 788 810 787 810 0.95 12 35 0.17 17 7.0 3.9 6 23 819 836 819 836 0.98 13 35 9.3e-05 0.0089 17.3 1.5 1 23 842 864 842 864 0.99 14 35 0.041 4 9.0 2.3 1 23 872 894 872 894 0.98 15 35 2.8e-05 0.0026 19.0 0.2 2 23 903 925 902 925 0.96 16 35 0.00095 0.091 14.2 0.1 2 23 932 953 931 953 0.95 17 35 3.4e-05 0.0033 18.7 2.5 1 23 961 984 961 984 0.96 18 35 3.9 3.8e+02 2.8 0.1 2 12 993 1003 992 1005 0.87 19 35 0.31 30 6.2 1.2 1 17 1021 1037 1021 1037 0.89 20 35 2.1 2e+02 3.6 0.9 2 23 1358 1380 1357 1380 0.95 21 35 0.17 17 7.0 3.9 6 23 1389 1406 1389 1406 0.98 22 35 0.00019 0.019 16.3 1.8 1 23 1412 1434 1412 1434 0.99 23 35 0.0048 0.46 11.9 1.4 1 23 1442 1464 1442 1464 0.98 24 35 2.6e-05 0.0025 19.1 0.3 2 23 1473 1495 1472 1495 0.96 25 35 0.001 0.099 14.0 0.1 2 23 1502 1523 1501 1523 0.95 26 35 0.38 36 6.0 0.9 2 23 1763 1785 1762 1785 0.93 27 35 4.5 4.3e+02 2.6 4.3 6 23 1794 1811 1794 1811 0.98 28 35 0.52 49 5.5 2.2 1 23 1817 1839 1817 1839 0.97 29 35 0.013 1.2 10.6 2.6 1 23 1847 1869 1847 1869 0.98 30 35 0.00044 0.042 15.2 0.3 2 23 1878 1900 1877 1900 0.96 31 35 0.62 60 5.3 1.0 3 23 1908 1928 1907 1928 0.95 32 35 0.00059 0.057 14.8 2.7 2 23 1937 1959 1936 1959 0.96 33 35 0.0013 0.13 13.7 0.1 2 23 1968 1990 1967 1990 0.96 34 35 6.8e-05 0.0065 17.8 3.1 1 23 1996 2018 1996 2018 0.96 35 35 3e-05 0.0029 18.9 2.0 1 23 2024 2047 2024 2047 0.98
Sequence Information
- Coding Sequence
- ATGGACGATTTTGCAGTGCCGGATGATTTCTTCTATCCCAAATATTGCATTCTGTGCTTGGAAACCAATGCTGCTTCTTATGTTCATATTTACTCAAAAGAAGGTACACAACTGGGCATAGAGAGGGTAATTGTAAAACACTTCTGGTTGCAGccaaatgaagaaaatatcaaaaaacgtTTTATTTGCCGTGATTGTTGGAAAATTGTGAATTGTTTTCACAAGTTCTATCTGCGAATAGAGAGTGCTCACAAACTTCTTCAAAACCAAATACCTGTGGTATTTTGCGAAAGTACCGTTGAAGATCCTATAGGTGAAAAAgctaatattgaaattgaaaaatgtgaaGACAGTTGTGTCACTCTTAAAAAGCCACGCCGTGGTCGACCTAAAACACAGAAGAACGAAGAACTATTATCAAATGTCGAGAGTATAGGCGAGAATGTAGGAATATCATTAAATACATTAAGAGAAACATCGACAAATAGTGCACGTCGTAGCGATcgattgcaaaaacaaaaagaagtcgatAAAATAATTAAGATAGAATATCCCGTTGAGGAAGCATGTGGATCCATTGATGAGGTaccaattaaaattgaatacgATGCAAATTCGCCTGATAATCATAACGAAGCATATTCTGATGAAGCAGCGGAAGACGATAAGGAATTTATAGCAGAAAAGAGCGAAAACCTAAAAAAGGTGGATCGGCGTGATGAATATATAGCGGAACATTTCTCTTTAACGTGTTTCATTtgtgaaaagggatttcaaaaatttatagcACTAAAGAGACACTTTAGAGCTGAGCATGAGGAGCAGGGTTACGCGGTATGCTGTAATAAAAAACTTTATAAGCGACACCTGCTCATCGATCATATTAAATCACACCAAAACCCACAGGCCTTCAAATGCCCACAATGCAATAAAGTTTTAGCTGTAAAACGCAGTTATGAATTACATTTGAAACGTCATGAAGAGAAGCGTGACCGCAAGTATCAATGCAAAATCTGCTCAAAGAAGTACTTTAATAAAGATATCTATCTGCGGCATATGATAGTGCATGCACCAGATGAACAAAAGACTATATCCTGTCCCGATTGTGAAAAAAAatttgtAACTCAGCACTTGATGATACGCCACCACAAAACGgtgcatttaaatttttatgctaTAATATGTGATGTTTGCGGCAAATCACTATGCAGCAAAGAGGCATTTGAACGTCATATGGTCGAACACTCTGGTATAGCTCTTCCAACTCATCAATGCGATATATGTGGCGTCAGAGTGACTAGCAAATATAATCTTGGAACACATAAAAAGCGTATGCATTCGGAGGAAGGTCAAAAACCACAAACCTGTAAAATTTGTGGCAAAACGTCACCAACACTAAATATTCACCGATATCACATGAAGTATATGCATACAATGAAACGCACACATGCATGCTCCTTCTGTATGAAAACATTTAAGCGGGAGACTAACTTGAAGGAGCATATGACAACACACACAGGTGGTGTTTTATATACGTGCACATATTGTCCGAAGACATTCAACTCGAACGCAAACATGTACGCACACCGCAAGCGTGCACATCCGAAAGAATGGGAGGAGAATCGCTTACAGAAATAcccaaattttcaaatatctcAGAAAAATGCACCAAGTGAAAAGACACCCAAGACACGCTCCATTTGTCGCCGTTGCTGGAATTCGGTGTATAgttttcatgaattttatttacaagtGGAACGTGCTCACAAACGTTTGGGACATGAAATACCTGTTGTGTATTGTGAAAGCATTATGGAAGATCCAATTGGAGAAAACGTTTATATTAAAGATGAATTAGATGAAAAGGATGAAGGGGTTCCACCTATTCATAAGGCAAAACGAGGTAAACCAcgtaaaagaaaacaaaatactgTTACATCAGGCGAATCAAAGATAGACGTAAATGTTAAAGATGAGCAAACGCAATTGGGATCAGAGGGATATTCGCAAGGAATAAATGACAATGAGCCATATTGTAGTTTGGCAAACGAATGGAAAACGAAATGTACAAATGGAGAACACGGTGCATCATCTAATTGCAAACGTCGCAGTGGTCGATTACAAAAACATAATGATATCGAGAGCGTAAGAGAGCACATTGAAGAATTTAAGAACGAAACTGAACCAGTTGAAGAATCAAATAATTTGCCTAaggtaaaagaaattaaaatcgaATTGACCTGCCAAAGTGAAGAACAAATCGATTTAACTGATCAAGAAAAAGAATCGAAATTAAGAAAAGAAGAGCGTGTGATGCAATTGGACAAATGGGatgaatatattgcaaaaaattttaccTTAATTTGTTCAGTTTGCCAGATTGAATTACCAAAATTTAGCACACTGAAGAGACACTTTCGCAGCGAGCATCAATTAAGTGGTTATGCGATATGctgtaacaaaaaattttttaaacgaTCTCATCTTAATGATCacataaaatttcatcaaaatccgGAAACCTTTAAATGCCCACACTGCAGTAAAATTTTGAGCGTACGTGCCAGCCTTGAATCACATATGAAACGTCACGAAGAGAAGCGTGAACGCAAATATCAATGTGAGACCTGCTTAAAAAGATTCTTcagtaaaacaatttttacaaatcATATGTTGGTGCACACACCTGAGGAGCAAAAGACTGTATCTTGCGTGGAATGTGAGAAAAAGTTTGCAACACAAGCTTTGTTAGAACGTCACCAAAAAACGGTACATCAAAATGTGAATGCAATTGTTTGCGATGTATGTGGGAAATCATTACGCGGTAAGGAGGCATTTGAACGCCACATGGATGAGCATGCAGGCACAGTTCGACCTACGCACGAATGTGAAATATGCGGTACGACGGTGAAAAGTAAATACAATCTAACCAGGCATAAAAGACAAATGCACTCCGAAGCCAATAGAACACCACAAACATGCCAAATTTGTGGAAAAGTATCATCTACAATAAATGTACATCGATACCATGTATATTACGTGCATAAGTTGCAACGTACACATGCGTGTACATTCTGTGATAAATCCTATAAACGGGCATTCAAATTAAAAccaaaTGAAAAGGCACCCAATACACGCTCCATTTGTCGCCGTTGCTGGAATTCAGTGTACAgttttcatgaattttatttacaagtGGAATGTGCACACGAAATTCTGGGACCTGAAATACCCGGTGTATATCCTGAAAGTATTATGGTACATCCAACTGAAAATAATGTTTATACTGAATATGAATTGGTTGAAAATGATGAAAGTATGGGACATGATATACCTGGTGTATATCCTGAAAGTATTATGGAATATAccattgaaaaaaatgtttatactgAATATGAATTGGTTGAAAATGATGAAAGTATGGGACACGAAATACCTGGTGTATATTCTGAAAGTATTGTGGAATATAcaattgagaaaaatttttataCTGAAGATGAATTGGATCAAAGTGATAAAAGGATGGGGCATGAAATACCCGGTGTATATCCTGAAAGTATTATGGAAgattcaattgaaaaaaatgtttatactgaagatgaattgtatgaaaatgatgaaaggGTTTCACATCTTCATAAGTCAAAACGAGAAAAATCGCATACAAAGAAAGAAGACTCAGTCCCACTATCGACGAAAGTATCTTCAGTCGATCCAAAGAAAAACGGATATGACGAAGATGAGCAAATTGAATTAGAATCTCATAGTATTTCGGGAAACGAATcgaaaacaataaatacaaataaaggaCAGTATGCATCATCTAATTGCAAACGCCGTAGTGTTCGCATACAAAAGCAAATAGATATTGATGTTGGAAAGGctcaaattgaagaaattgaaaacaaaatggAACCTAGTGAAGAATCAGCAAATGTACACAATGGAAAAGCACATCTCGATTTAACTGATCAATTAATTGCCGATAAGGATAAAAATATAGGATCGAAATTAGGAAAAAGATTGAAATTGAACAAATGGGATGAacatatcgaaaagaatttcaCCTTAACTTGTTCAGTTTGTCATATTGTATTACCGACATTTACCATATTGAAGAGACATTTTCGTAGCGCACATCAATTAAATGGTTATGCGATATGctgtaacaaaaaattttttaaacgaTCTCATCTTAATGATCacataaaatttcacaaaaatccgGAAACCTTCAAATGCCCACACTGCAGTAAAATATTGAGGATACGTGCAAGTCTGAGAGCACATATGAAACGTCACGAAGAGAAACATGAACGCAAATATCAATGTGAGACCTGCTTAAAGAGATTCGATAGTAAAACTGTTTTTACAAACCATTTGTTGGTGCATATACCTGAGGAGCAAAAGACTATATCTTGTTTGGAATGTGAGAAAAAGTTTGCAACACAGGCTTTGTTAGAACGTCACCAAAAAACTGTACATCAAAATGTGAATATAGTCGTATGCGATGTATGTGGAAAATCTCTACGCGGTAAGGAGGCATTTGAACGCCATATGGATGAGCATGCAGGCACAGTTCGATCTATTCACCCCAATGAAGAGAGTCCGAGAACACGCTCTATTTGCTCCAAATGCTGGAACTCTGTGTATTCCTTTCATAAATTCTATTTACACGTAAAACGTGCTCACGAACTTTTGGACGAGAAAGTACCTGTTGTGTTTTGTGAAAGTGCTGTAGAAGATCCCATTGGTGACAATATTCATATCAAATTGGAATTAGATGAAAAAGTTGAAGAGGTAGAAGTTGTTAATAAATCTAAACGAGGTAGACCACGAACTAAGAAATGTATAAACACATTATCAGCTCAAGCATATTCAATCGGTTCTCGAAAAAGtgttaaaagtgaaaatatagaATTTGTATTAGAAGATGTAAAAACACTGACGCCTATCGACCGAGATCTAAGTGAACTGAATAATGCAAATATAGAATCAGAAATAGAATCGTCCGTTTGCACACGTCGAAGTGGTCGTTTGCAAAATCAAAAGAAGCGAATACCGACTATTCCTAAAGAAGAGTTGAAGAACGAAGAACAGCCTGTTGAGCAATCAGATGCAGCTAAGGCAGAAGCCGTTCAAGGCGAAGATGATAAACCACATTTTGACTTAGACGATCAAATAATTCAAGCAAATAGCGCAAAGAAGAAATCCAAAAAAGATAAAAGTGAATATTTAGCGCAGTCGGAAAAATACGATGAATATATCGCTACGAATTTCAGTCTAACTTGTCCTCTTTGTCATATCGATTTGCCAACTTTTAAcacattaaaaaaacatttcCGCGATGGACATAACTTACGTGGCTATACAATATGCTGCAATAGAAAATTCTTTAAGCGCTGTCATCTCATTGATCACATCAAGCTACATCAAAATCCGCAAACATTTAAATGCCCTCATTGTAGTAAACTATTAGGAGAGCGTCGCAGTTATGAGTTGCATGTGAAACGCCACGATGAGAATCGCGATCGTAAATATCAATGTAAGATCTGTTCAAAAAGATATTTTAGTAAGACCATTTATAAGCGTCATATATTGGTTCATGCACCCGAGGAGCAAAAAGTCGTACCGTGCTTATATTGCGAGAAAAAatttgcaacaaaatatttgaTGGAACTTCATTACAGAACGGtgcatttaaatttgtatgcgAAATTTTGTGAAGTATGTGGAAAATCAATACGTGGCAAATATGCTTTTCAGTGTCATATGGAGGAGCATTCTGGTATTACTCAGCCAATATGTCAATGTGAAACATGTGGTGCCAGATTAACaagcaaatataatttatcGAAACATATAAAACGTATGCATTCAGAAGAAAGTCAAACACCACAAACGTGCAAAATATGTGGAAAGGTATCGCCGGGCTTATCAGCACTTCGGTACCATATGAATTATATGCATAGGCTGCAACGAATACATGCATGTACGTTTTGTGATAAAACATTTAAGCAAGCGACCAGTTTAAAAGAGCACTTAACAACTCATACTGGTGGTGTTTTATATACGTGCACATATTGCCCAAAAACATTCAATTCCAACGCGAATATGTATTCACATCGCAAGCGCGCACATCGAAAAGAGTGGGAAGAGAATTATCTGCAAAAGTATCCTAAATCGAAAGTGGCACTTACATGTGAAGGTGGCACTGTGAAGAtgtga
- Protein Sequence
- MDDFAVPDDFFYPKYCILCLETNAASYVHIYSKEGTQLGIERVIVKHFWLQPNEENIKKRFICRDCWKIVNCFHKFYLRIESAHKLLQNQIPVVFCESTVEDPIGEKANIEIEKCEDSCVTLKKPRRGRPKTQKNEELLSNVESIGENVGISLNTLRETSTNSARRSDRLQKQKEVDKIIKIEYPVEEACGSIDEVPIKIEYDANSPDNHNEAYSDEAAEDDKEFIAEKSENLKKVDRRDEYIAEHFSLTCFICEKGFQKFIALKRHFRAEHEEQGYAVCCNKKLYKRHLLIDHIKSHQNPQAFKCPQCNKVLAVKRSYELHLKRHEEKRDRKYQCKICSKKYFNKDIYLRHMIVHAPDEQKTISCPDCEKKFVTQHLMIRHHKTVHLNFYAIICDVCGKSLCSKEAFERHMVEHSGIALPTHQCDICGVRVTSKYNLGTHKKRMHSEEGQKPQTCKICGKTSPTLNIHRYHMKYMHTMKRTHACSFCMKTFKRETNLKEHMTTHTGGVLYTCTYCPKTFNSNANMYAHRKRAHPKEWEENRLQKYPNFQISQKNAPSEKTPKTRSICRRCWNSVYSFHEFYLQVERAHKRLGHEIPVVYCESIMEDPIGENVYIKDELDEKDEGVPPIHKAKRGKPRKRKQNTVTSGESKIDVNVKDEQTQLGSEGYSQGINDNEPYCSLANEWKTKCTNGEHGASSNCKRRSGRLQKHNDIESVREHIEEFKNETEPVEESNNLPKVKEIKIELTCQSEEQIDLTDQEKESKLRKEERVMQLDKWDEYIAKNFTLICSVCQIELPKFSTLKRHFRSEHQLSGYAICCNKKFFKRSHLNDHIKFHQNPETFKCPHCSKILSVRASLESHMKRHEEKRERKYQCETCLKRFFSKTIFTNHMLVHTPEEQKTVSCVECEKKFATQALLERHQKTVHQNVNAIVCDVCGKSLRGKEAFERHMDEHAGTVRPTHECEICGTTVKSKYNLTRHKRQMHSEANRTPQTCQICGKVSSTINVHRYHVYYVHKLQRTHACTFCDKSYKRAFKLKPNEKAPNTRSICRRCWNSVYSFHEFYLQVECAHEILGPEIPGVYPESIMVHPTENNVYTEYELVENDESMGHDIPGVYPESIMEYTIEKNVYTEYELVENDESMGHEIPGVYSESIVEYTIEKNFYTEDELDQSDKRMGHEIPGVYPESIMEDSIEKNVYTEDELYENDERVSHLHKSKREKSHTKKEDSVPLSTKVSSVDPKKNGYDEDEQIELESHSISGNESKTINTNKGQYASSNCKRRSVRIQKQIDIDVGKAQIEEIENKMEPSEESANVHNGKAHLDLTDQLIADKDKNIGSKLGKRLKLNKWDEHIEKNFTLTCSVCHIVLPTFTILKRHFRSAHQLNGYAICCNKKFFKRSHLNDHIKFHKNPETFKCPHCSKILRIRASLRAHMKRHEEKHERKYQCETCLKRFDSKTVFTNHLLVHIPEEQKTISCLECEKKFATQALLERHQKTVHQNVNIVVCDVCGKSLRGKEAFERHMDEHAGTVRSIHPNEESPRTRSICSKCWNSVYSFHKFYLHVKRAHELLDEKVPVVFCESAVEDPIGDNIHIKLELDEKVEEVEVVNKSKRGRPRTKKCINTLSAQAYSIGSRKSVKSENIEFVLEDVKTLTPIDRDLSELNNANIESEIESSVCTRRSGRLQNQKKRIPTIPKEELKNEEQPVEQSDAAKAEAVQGEDDKPHFDLDDQIIQANSAKKKSKKDKSEYLAQSEKYDEYIATNFSLTCPLCHIDLPTFNTLKKHFRDGHNLRGYTICCNRKFFKRCHLIDHIKLHQNPQTFKCPHCSKLLGERRSYELHVKRHDENRDRKYQCKICSKRYFSKTIYKRHILVHAPEEQKVVPCLYCEKKFATKYLMELHYRTVHLNLYAKFCEVCGKSIRGKYAFQCHMEEHSGITQPICQCETCGARLTSKYNLSKHIKRMHSEESQTPQTCKICGKVSPGLSALRYHMNYMHRLQRIHACTFCDKTFKQATSLKEHLTTHTGGVLYTCTYCPKTFNSNANMYSHRKRAHRKEWEENYLQKYPKSKVALTCEGGTVKM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -