Basic Information

Insect: Megalurothrips usitatus
Gene Symbol: Znf423
Assembly: GCA_026979955.1
Location: CM049600.1:10284442-10291425[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.17 13 5.9 5.9 1 23 3 25 3 25 0.98

2 23 4.8e-07 3.7e-05 23.4 2.2 1 23 31 53 31 53 0.99

3 23 1.5e-05 0.0011 18.7 0.2 1 23 59 81 59 81 0.98

4 23 0.0011 0.087 12.8 2.3 1 23 118 141 118 142 0.94

5 23 0.0018 0.14 12.1 0.5 2 23 264 286 263 286 0.95

6 23 7.1 5.4e+02 0.8 0.1 5 23 304 323 302 323 0.86

7 23 0.13 9.8 6.3 0.0 3 23 415 435 414 435 0.97

8 23 0.79 60 3.8 0.2 2 10 513 521 512 522 0.89

9 23 0.00067 0.051 13.5 0.1 3 23 553 574 551 574 0.94

10 23 0.56 42 4.3 0.1 1 23 579 602 579 602 0.92

11 23 0.00075 0.057 13.3 0.5 1 23 739 762 739 762 0.98

12 23 6 4.6e+02 1.0 0.1 3 23 821 843 820 844 0.79

13 23 0.00057 0.044 13.7 4.7 2 23 868 889 867 889 0.96

14 23 0.016 1.2 9.2 0.8 1 23 903 925 903 925 0.98

15 23 0.013 0.99 9.4 0.1 3 23 934 954 933 954 0.97

16 23 7.1 5.4e+02 0.8 0.1 2 23 978 999 977 999 0.93

17 23 0.0068 0.52 10.3 0.0 2 23 1114 1136 1113 1136 0.95

18 23 0.91 70 3.6 0.2 1 23 1140 1162 1140 1162 0.94

19 23 0.26 19 5.4 0.3 2 23 1172 1193 1172 1193 0.95

20 23 0.0017 0.13 12.2 0.0 1 23 1201 1223 1201 1223 0.97

21 23 0.015 1.1 9.3 3.0 1 23 1230 1252 1230 1253 0.94

22 23 0.0035 0.27 11.2 0.0 2 23 1348 1370 1348 1370 0.95

23 23 0.33 25 5.0 0.0 2 23 1386 1408 1385 1408 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.17	13	5.9	5.9	1	23	3	25	3	25	0.98
2	23	4.8e-07	3.7e-05	23.4	2.2	1	23	31	53	31	53	0.99
3	23	1.5e-05	0.0011	18.7	0.2	1	23	59	81	59	81	0.98
4	23	0.0011	0.087	12.8	2.3	1	23	118	141	118	142	0.94
5	23	0.0018	0.14	12.1	0.5	2	23	264	286	263	286	0.95
6	23	7.1	5.4e+02	0.8	0.1	5	23	304	323	302	323	0.86
7	23	0.13	9.8	6.3	0.0	3	23	415	435	414	435	0.97
8	23	0.79	60	3.8	0.2	2	10	513	521	512	522	0.89
9	23	0.00067	0.051	13.5	0.1	3	23	553	574	551	574	0.94
10	23	0.56	42	4.3	0.1	1	23	579	602	579	602	0.92
11	23	0.00075	0.057	13.3	0.5	1	23	739	762	739	762	0.98
12	23	6	4.6e+02	1.0	0.1	3	23	821	843	820	844	0.79
13	23	0.00057	0.044	13.7	4.7	2	23	868	889	867	889	0.96
14	23	0.016	1.2	9.2	0.8	1	23	903	925	903	925	0.98
15	23	0.013	0.99	9.4	0.1	3	23	934	954	933	954	0.97
16	23	7.1	5.4e+02	0.8	0.1	2	23	978	999	977	999	0.93
17	23	0.0068	0.52	10.3	0.0	2	23	1114	1136	1113	1136	0.95
18	23	0.91	70	3.6	0.2	1	23	1140	1162	1140	1162	0.94
19	23	0.26	19	5.4	0.3	2	23	1172	1193	1172	1193	0.95
20	23	0.0017	0.13	12.2	0.0	1	23	1201	1223	1201	1223	0.97
21	23	0.015	1.1	9.3	3.0	1	23	1230	1252	1230	1253	0.94
22	23	0.0035	0.27	11.2	0.0	2	23	1348	1370	1348	1370	0.95
23	23	0.33	25	5.0	0.0	2	23	1386	1408	1385	1408	0.94

Sequence Information

Coding Sequence: ATGCCGTTCCGGTGCGAGTTCTGCAGCCGCCTGTTCAAGCACAAGCGCAGCCGGGACCGCCACATCAAGCTGCACACGGGCGACAAGAAGTACCGCTGCAACCAGTGCGAGGCCGCCTTCAGCCGCAGCGACCACCTCAAGATCCACATGAAGACGCACGACAACCAGAAGCCGTTCCAGTGCACGGTCTGCAACCGCGGGTACAACACGGCCGCCGCGCTCACCTCGCACATGCAGAACCACAAGAAGGCGGCGGACGCGGCGTCCAACGGCGGCGCCTCCAACTCCAACGGCGGCCGGTCGTCGTCGCGCGCCTCGGCCTCCTCGGACAACACGCCGTCGCCGGGAACCTTCCGCTGCCTCCAGTGCGGCGACTGCTTCCGCAAACCCGAGGACCTGCAGAGCCACATGGCCGGCCAGCACCACGTCGACATGGGGTCGCCGCCGTCCCGAAGCGCCTCCCGGGGGCTGCTGCTGGACTCGCCCCTGTCGCGGTCCCCCTTCCCGCTGCCCGGGCTGGCCTCCAGCCTGGCCTGTATGTACTGCACGAAGGACAACTTCGGCAGTATGGAGGCCCTGCAGCTCCACGTCCAGGCCATGCACGGCGCACTCCTGAACGGCGAGCTGAGGGACTTGGCGGCGCAGGCGGCGCGGTCCCGCCCCCCGGTGGAGGACTCCCTGAGGGGGTCGCCCACCACGCCGTCACCGTCCGGGCCCACCACGCCGGGCAGCGCCAACTCAGGCAGCGGCGGCAACTCCAGCAGCGGCAGTGGCGGCGGGCCCCTCATCCCGTGCGAGCTGTGCACCATGAGGTTCAATTCCATCTCCGGCCTCCACAAGCACCAGCGCGCCGTCCACGGACTCGTCGGGCCCAAGTTCCTGGGCGACCCATCCCCGATCCTGTGCATCCACTGCTCGCTGCCCTTCCCCTCGTCGGCGGCCTTCGCCGAGCACTACGTCCTGGTGCACGGCGGCGGCGCTAGTCCGGCAGCCCTGGCGGCCATGTCGGCGAGGACGCCGTCGCCCGCGGGCCGCGACAGGGAGAGGGAAAGAGACAGAGACAGGGAGCGTGACCACCAGCAGGAGAAGCCCACCGACCTGACCGTGAGCAGGAAGGTTCCCTCTCGGCGGAGCGGCGAGGACAAGGGGCCGCCGTCGAAGAGGTCCAAGTCCAACCTCGAGGCGCCGCCGCTGCTGCTGGACGGGCTGATGGGCCGAGACTACGAGGCGGGCCCCCTGCTGTGCAACCAGTGCGGAGCCGCGCTGCCCGACTTCGAGGCGTTCCGCGCCCACCTCAAGGCCCACCTGGAGGAGTCCGGCGCGGGACTGCGCTCGCTGCTGGGGGCGGACCTGCTGGGGCTCCTGCCCCCCGGCCCCACCTCCGGGCCACCCCTTGGTCCCCTGGGGCCTCTCGGTCCTCTGGGCGCCTTGGGGCCGCCCCCCGCGGCGGAGGAATCGCTGTCCTCGCGCAGCAATCGCCGCAGCCCCGCCGCCGCGTCGCCCGGCTCCGGCGGACACGGCCTCGGGCACGTCCTCAGCTGCCCGCACTGCGGCGTGTCCTTCCCGGCCGGCACGTCGGAGGAGCGGCTCGGCGTCGGAGCGCTACTCGAGCGCCACGTGGCCGAGCACTTCCTGGCCACGGCCACCGAGTTCGGCTGCCCGACCTGCAGCAAGCTGTTCGCCAAGCCGGACGAGCTCCAGAAGCACCTCATGGACATCCACGCGCACCACCTGTACCGGTGCGCGCTCTGCCAGGAGCTGTTTGACTCCAAGGTCGCCATCCAGGTGCACTTCGCCGTCAAGCACTCGTCCGCGTGCCCGCTGTACCGGTGCACGGCCTGCTCGGCGTCCGCGCCCGCCTCCAGCGCCGTGTTCCGGTCGGACCGCGAGTTCGGCCACCACGTCCGGACGGCGCACGCCTCGCACCCGCTGCTGACGGCCACGCACGCCATGCTGCTGCAGTACCAGCAAAAGATGCAGCAGCGCGAACAGCGCGAGCACCACCGCGAGCAGAGGGAGCGGGACCGCGGCCGGGACCGGGAGCAGCGGGAGCGCGAGCGAGACCGCGACAGGGAGAGGGAGAGATCGCGGGAGCGGGAGCGAGAGCGTGAGTCCGGCGGGGAGGCCGCGGGGGCGTACCGCTGCCTGTTCTGCCGGGCGTCCTTCGGCTCCGAGCTGGAGCTCCAGTTCCACCTGCCCACGCACACGCGCCAGTTCAGCTGCCCGCTCTGCCAGGAGACCTTCCAGGTCGAGTTCCTGCTCGACAAGCACATGCAGACGCAACACTCGGGGCAGACTCTGCTCAACGGCCGCGACACCCCGTCCGTGCCGCTGTCCCTGGCTGCACCCGAGGACCGGGAGCGCAAGCCCAAGCCCAAGCAGCCCAACGGCTGCCCCAAGGCCAACGGTCAGGGCGACGCGGCGGATCCGCTGCTCAACAACAACCAGGCCGGCGCCTCGTGCGAGATCTGCGAGCGCGGCGACTTTGCCAGTGAGGCGGAGCTGGCCGCCCACCGGAAGCTCGCCCACCACAAGGCGCAGGGCCAGGGCGGCTCACCCAGCGCCGCCACCAAGAACGGCCAGGGCCACGCCGTCAGCCTGCACTGCGCCTACTGCCAGGAGACCTGCAAGTCACGGACCGAGCTGGAGAACCACATGAAGACGCACTCGCACCAGGGGACGGCCGGGCTGGGCGGCACGGGCAAGCATAAGTGCAACATCTGTGACGAGCTGTGCCCCTCGGCGTCCGTGCTGGCCGAGCACAAGCTGACCCACTGCAAGGTGGTCCAGGGCTCGGCCTGCACGGTGTGCCGCGCCTCCGTCGCGACCGAGGACCAGTTCCGCGCGCACCTCCGCCAGCACGCCGCGCAGGCGCAGCCCGCGCAGCCCGGCAACCCCCCGGCCGCCAACGCGCCGCTGTGTCTGCCGGTGCAGTGCGTCATCTGCAGGCAGACGCTGGTCTCCGACGTGGAGGTGCGGCTGCACGCCCGCTTTCACCTGCAGGGCACCAAAGACGGCCAGGGTGTCGAGCAGCCCGCCGACTCCCCCGAGGCCCCGGGCGTCCCCGGTGTGGCCACGTGCTGCATCTGCCTGCAGACCGGCGAGGCGGCCTCCATGGTGCCCACGAGCGCAGCGCCGCTCCCCGGCCAGTCAGTGTCGTACGTGTGCGCCGACTGCTACCGGCGGCACTCCAAGATGTCCTCCCCCCAGCCGCAGCTGTCGCCCTCGCGCACTGGCCAGGACGAGGCCAAGCAGCAGGAGTCCCGGGGGCAGACGACGGGGTCCTCGGGGTCCGGGGACAAGCAGGCGTCGTCCGTGCAGGGCGCCGACTCTACGCAGCGCTGCGGGGAGTGCGGCGTCAAGACCGAGTCCGCGGCCGCCCTGGAGGCGCACATGGCCGTAGCCCACAAGAACACCTACCAGTGCATCAAGTGCCAGGCGAGCTTCGAGACGGAGCGCGACATCCGGCTGCACGTGTCCGCGCACCTCCTGGCCGAGGGCTCGTCCGCCAACGAGTGCCGCCTGTGCCGCCGCCAGCTGTCCACGCCACTGCAGCTGCAGCTGCACCTCATCGAGCACACGTTCGCCGGCTGCGCCTCCTTCAGCTGCTACATCTGCAGCGCCGTGTTCACCGCCGCCCGCGGCCTCCAGGCGCACATGCTGGAGCACGGGCTGACCGCGCGGCCCTACGACTGCTCGCACTGCGGCCTGCGCTTCTTCTTCCGCGCCGAGCTGGACAACCACACGCTGGGCCACCACGCACACGCCATGGCTCTCGGCCAGGGCCAGGGCAGGGCAGGCGACGACGAGGACGCCTCGGTGCATCAGGCTGCGGCGGCCGCCGCTCAGGCCTCCTTCTACCAGCACCTGAACGGGCTGGATCTGTACTACACCGTGCCTAACAGCTCCAACAACGACGCCGCCAAGTCCCCGCGTAAGTCCCCTGGCCGCAGCAACGGCAGGGACCGCGACCGGGACCGGGACCGGGAGGCCGGGCGGAGCAGCAGCGGCGGTGTGGGCGTGGCCGGCGCCGTGAAGCCCCGCTGCCTCATCTGCGGCAAGGAGCTGGCCTCGGCGCGTGCCCTGGCCAACCACCTTCGGGCCAGCCACGGCGTGCAGGATAACGGGCTCGTGCAGGGGCAGCCCGAGCTGCAGGTGTGTCTGCTGTGCAAGGAGGTGCTGCCCGACCGCGACGCGCTGCTCCTGCACCTCGCCGTCCAACACCCCGGGCCCGGCGCCGCGGCCTTGCCGCTGCAGCTGGACGCCCACATGACCCTCCTCGGGCAGGCACACCATGCCCTGCAGCAGCACGTGAAGCAGGAGCCTGCCGCCGTCAAGGAGGAGCTGGAGGACGATGATGCTGTGGACCGTGACCGCGCCGACGCCGCCACGCCCGCGCCTGCGGCAGCACCTGCAGCAGCACGAGCACCCTCTCCGGTGTCGTCAGCGTCAGCTCTCGAAGGCGTGGACGCCGTCGTGGGCGACGCTGACGACTCGGACGACGCGTTGGAGTCTGTCGAGGTCACGGTGAAGGGAGATGGCGTCGATGGCGTTAAAGAGGCGGACGACGGAGAGCCCGGCTCAGGCACGCCAAGTGACGGCGAGCTGAAGGACGCCTCCCTTGTAGAGGAAGGGAAGAAATTGGACGATGAGGCAGAGGACGCCAAAGTTGATTCGTAA
Protein Sequence: MPFRCEFCSRLFKHKRSRDRHIKLHTGDKKYRCNQCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKAADAASNGGASNSNGGRSSSRASASSDNTPSPGTFRCLQCGDCFRKPEDLQSHMAGQHHVDMGSPPSRSASRGLLLDSPLSRSPFPLPGLASSLACMYCTKDNFGSMEALQLHVQAMHGALLNGELRDLAAQAARSRPPVEDSLRGSPTTPSPSGPTTPGSANSGSGGNSSSGSGGGPLIPCELCTMRFNSISGLHKHQRAVHGLVGPKFLGDPSPILCIHCSLPFPSSAAFAEHYVLVHGGGASPAALAAMSARTPSPAGRDRERERDRDRERDHQQEKPTDLTVSRKVPSRRSGEDKGPPSKRSKSNLEAPPLLLDGLMGRDYEAGPLLCNQCGAALPDFEAFRAHLKAHLEESGAGLRSLLGADLLGLLPPGPTSGPPLGPLGPLGPLGALGPPPAAEESLSSRSNRRSPAAASPGSGGHGLGHVLSCPHCGVSFPAGTSEERLGVGALLERHVAEHFLATATEFGCPTCSKLFAKPDELQKHLMDIHAHHLYRCALCQELFDSKVAIQVHFAVKHSSACPLYRCTACSASAPASSAVFRSDREFGHHVRTAHASHPLLTATHAMLLQYQQKMQQREQREHHREQRERDRGRDREQRERERDRDRERERSRERERERESGGEAAGAYRCLFCRASFGSELELQFHLPTHTRQFSCPLCQETFQVEFLLDKHMQTQHSGQTLLNGRDTPSVPLSLAAPEDRERKPKPKQPNGCPKANGQGDAADPLLNNNQAGASCEICERGDFASEAELAAHRKLAHHKAQGQGGSPSAATKNGQGHAVSLHCAYCQETCKSRTELENHMKTHSHQGTAGLGGTGKHKCNICDELCPSASVLAEHKLTHCKVVQGSACTVCRASVATEDQFRAHLRQHAAQAQPAQPGNPPAANAPLCLPVQCVICRQTLVSDVEVRLHARFHLQGTKDGQGVEQPADSPEAPGVPGVATCCICLQTGEAASMVPTSAAPLPGQSVSYVCADCYRRHSKMSSPQPQLSPSRTGQDEAKQQESRGQTTGSSGSGDKQASSVQGADSTQRCGECGVKTESAAALEAHMAVAHKNTYQCIKCQASFETERDIRLHVSAHLLAEGSSANECRLCRRQLSTPLQLQLHLIEHTFAGCASFSCYICSAVFTAARGLQAHMLEHGLTARPYDCSHCGLRFFFRAELDNHTLGHHAHAMALGQGQGRAGDDEDASVHQAAAAAAQASFYQHLNGLDLYYTVPNSSNNDAAKSPRKSPGRSNGRDRDRDRDREAGRSSSGGVGVAGAVKPRCLICGKELASARALANHLRASHGVQDNGLVQGQPELQVCLLCKEVLPDRDALLLHLAVQHPGPGAAALPLQLDAHMTLLGQAHHALQQHVKQEPAAVKEELEDDDAVDRDRADAATPAPAAAPAAARAPSPVSSASALEGVDAVVGDADDSDDALESVEVTVKGDGVDGVKEADDGEPGSGTPSDGELKDASLVEEGKKLDDEAEDAKVDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -