Basic Information

Insect: Megalopta genalis
Gene Symbol: -
Assembly: GCA_011865705.1
Location: NW:9927-25437[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0082 0.44 10.2 5.2 1 23 617 640 617 640 0.91

2 15 0.043 2.3 8.0 1.2 5 23 647 666 645 666 0.93

3 15 0.0032 0.17 11.5 2.4 2 23 673 694 672 694 0.96

4 15 1.1 57 3.6 4.2 2 21 722 741 721 742 0.93

5 15 0.011 0.6 9.8 5.4 1 22 825 846 825 846 0.92

6 15 0.0026 0.14 11.8 6.5 1 23 853 876 853 876 0.93

7 15 1.1 57 3.6 5.8 1 23 886 909 886 909 0.96

8 15 0.07 3.7 7.3 0.1 3 19 933 949 931 951 0.93

9 15 0.0072 0.38 10.4 2.6 1 23 959 982 959 982 0.97

10 15 6.5 3.5e+02 1.1 4.6 1 23 993 1016 993 1016 0.84

11 15 0.016 0.85 9.3 0.1 1 20 1048 1067 1048 1069 0.94

12 15 0.0099 0.53 10.0 3.8 1 23 1108 1131 1108 1131 0.93

13 15 1.2 62 3.5 2.0 1 19 1161 1179 1161 1181 0.82

14 15 0.00029 0.015 14.8 5.6 1 23 1189 1211 1189 1211 0.98

15 15 0.0017 0.09 12.4 1.4 1 23 1221 1244 1221 1244 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0082	0.44	10.2	5.2	1	23	617	640	617	640	0.91
2	15	0.043	2.3	8.0	1.2	5	23	647	666	645	666	0.93
3	15	0.0032	0.17	11.5	2.4	2	23	673	694	672	694	0.96
4	15	1.1	57	3.6	4.2	2	21	722	741	721	742	0.93
5	15	0.011	0.6	9.8	5.4	1	22	825	846	825	846	0.92
6	15	0.0026	0.14	11.8	6.5	1	23	853	876	853	876	0.93
7	15	1.1	57	3.6	5.8	1	23	886	909	886	909	0.96
8	15	0.07	3.7	7.3	0.1	3	19	933	949	931	951	0.93
9	15	0.0072	0.38	10.4	2.6	1	23	959	982	959	982	0.97
10	15	6.5	3.5e+02	1.1	4.6	1	23	993	1016	993	1016	0.84
11	15	0.016	0.85	9.3	0.1	1	20	1048	1067	1048	1069	0.94
12	15	0.0099	0.53	10.0	3.8	1	23	1108	1131	1108	1131	0.93
13	15	1.2	62	3.5	2.0	1	19	1161	1179	1161	1181	0.82
14	15	0.00029	0.015	14.8	5.6	1	23	1189	1211	1189	1211	0.98
15	15	0.0017	0.09	12.4	1.4	1	23	1221	1244	1221	1244	0.95

Sequence Information

Coding Sequence: aTGGCACGAGTTTATGTATACGAACGCCCAGTGGATGCTGTTTCGACGAATGAGTCCTTCTATGAGAAATTGAATTATGTTACAACTGCACTGCAGATCAAACAAGAGCCAATTTCTACAGATGACAATTGTCAGGACAGTACTTTGCCATTGGCGGATATCAATACCAATACCACTACCGTAACGGGTGAAACAATTGTTCGGGAAACACAACTATGGAATAACGTAAATAATCAAGAGAATGAGCTTGTGTTATCCAAGTACCGGAATGATACAGATCTATCAGGCACGAACGTCGTCAATACGCAAAAGCGTAAATGTTTAGCATTTGAGAATTTTGAAGTGTCTGAGAAAAAACTCGGCGTTGGACTTAAGTCGCCGGAATCAATCGAAGCAACGATTGAATCTGACGTATGTTTCTTAAACTTTAAGTCATTGATGGCGTCAAAGGTTCACACAGATTATCAGACTGACGGGGCCCTAcctttttgtaataaatatcataCAATTTGTAAATCAGCTCACTTTTTAGATGAACAGAAATGGATGCGTAGGTGCAAAATCAAGACAAAGGTATCATTTTGCTGTCGTTTCTGTACGGCTAAATACAGAAcgaaatcgaatttaaaatgCCACGTGTTCCACAACCACAGTAAATTATTACCTTTCTCTGCAGAGAAAGCTGATAATCATAGTGAAACTGATAAAtctagtaaaattaaaaagatcaaAACTGATGAAACTAATGAAACTGACAAACTTAGTGAATATTGTGAAACTAGAGAAACTAGGGAAATTGATAAAACCAGTAAAATGCAATTGACAGAGAACACTGATAATTACGTAACAAGTCCTTCTGTACATCAGAACGGAAATGATAAAATCGACCCTACTCCcacaaaaatgaaacaaacgacTATTACTCAGTTCCTTTCAGAGTACACGAGAATAACAGAAGATTTTTGTCCAAACAAAGTTCGTAATCCAAAAAAAACTCTGAAAAAAGTGATACCTAGACAAAATAAGACACTAACAGAGAAAATTGATCATTGTGTCGAAACTCCGAAAATAGCCATACCTAGTCAAATGAAAACGATATTGGAGGCATCCGAACCTCAAGGGGAaggccgaaggaaaattgtaaCTAGACGAAGCGGCACGACAAGAGAGAAAGTTAATCTACATCTAAAAACTCAGAAGATAACTAGACAAAGCGGAACAGTAGTAAAATCACTTTCCACTCTTACCAATGAGAAAACATTGATTACCACTGAAAGCTCTACGCCGAATGGCAGCACAACTGAGGAAAACAGTTCATTTGTCAAAATACACATTGGTTGCGACATGATGAAGGCCTTGTTGAATAAGATCATAAAAACCGAATTAAAAGCTGAACCTTGTCATTTCGCGTTAGAAAATCACAACCTTCAACGCGTGACAAGAAGTAGTCTTAGACGATCGTTAAATGACTTAAATACAACTCCTGTGATAAAATCTCCTAAAAGAATTAGGTTTAGAAAGCGAGCCGCTAGCACGCCTAAAGAAAAAGCTGAGCATCAGTCGACGGAGAAGGAACTGAGAGCAAAATTCAAATGTAAAAACTTAAAAGTTAATCTAGTTAGATGCGACATGGTCGTTAAAACAGAAACTGTTGACGTCACTCAGATTTCAGTGGAAGGAGacgaaaaaattgcagaaatgtGGCAAAAGAAGGTGACGTTAAATAGAGAAAATGCTCCACTAGTCAAAGTGAATGAACTCATAAAAGTAGAAGTTAAAGAACCGTTCCTATGCTCAGAGGTGTCTAATGCACATCGAGACAACACGAAAGCCAATTCGCGTATACTGTTCCGGTGTAAAGCTTGCAAAAAATGCTTCCccataaagaaaaatttacgTAAACATTTCGAGCTGCGCCACGTGTTCTTCAAATCGAGCATATGCGACGCTAAGTGCAAAACTAAATTTGAATTGCAGAAACACTACATGAACAAACACAGCGGTTTCAAGCGCATGCAGTGTTGCGTGTGCTTTAAGAAGTTCTCATCACTAGTGATGTTGAAGCAGCACCTCATACTACACTGTACCCAAGTACTGCTACCTAAACGCAAGAAACAATGTATCAAAGAAGTGATCAAGTGTAGGATGCCCGATAAGAAGTGCTCGTGCAAGGCTTGCGGCAAGCGATTTTGGTTGAAGTCCTGTTTGAAGGAACACCAAAAACTGTGTACTAAAATGAGGGGGAGGGAGAAGCAGTCGCAAAACGTGTCTAATACCGTGGAAACATCAACGAAACGAGTATTGGATGACGCGAACATTAAATTGAATGCGCCACAATCTAAGTTATGTTTGATCAACGAGTATTCTAATGGGGCTATATCACCGCCAATGAAACAAACGAAGATGTTGTTGAGGGGTACCACTTTTGCGAAGGGATACACCATAGACTATTCTGGCGTGAATAAGAACACATTCGATTGCACTACTTGCAATAAGCACTTCCGAACATTTCGAAACTTATGTATGCACGAACAGACCTACTCCAAAGCCGCCACGCATGTTTGCACGATCTGCAACACCGCGTTCAGCACCAGGACATTACTGCACCGTCATCATCAATTCACCCACACGTTCAAGACTCTTACAAAGCACAAGTACTTCTGTACGTTCTGCACTCAGGGTTTCCGGAAGAAGATGAAGATTCAGATTCACACGAGACACTTTCATGCTGGTGACACACCCATCATTCCCATACCATGGTTAGAGTGCACCGAAGACTGGGAGGTGAGCACAATATGCAGCGTGTGTAAGCTAGAGTTCAATTCCAGCGAACAGTTCATTCAGCACAATATGTTTTACTATAAGGGTCAAATATTCACCTGCGCGTTCTGCAGTAAAACCTTCCAAGGATTGTACATGCTGCACAGTCACATTAAATCCGAGCACAACACGGAAGATGTGAAGAAACAGTACACGTTCACATGCGACATTTGCAACGAGGGCTTCATCATAGAGTCACATTGTCATGCGCATAAATTGCACGTACATTCGATGTTGCATGAGTCTTCGCAGTACCTACAAGATCATGCCTATGTTAGTGCGGCGAATGGAATGGAATCGACGAATGGACCGATTCCGAAATACAACTGCAATATTTGCCACATGATTTTTATAGCTGAAGAAGACCTGCGTCAACACAAAATGGAGTACACTAATGACGGCAATTACTTTTGCTCTTTCTGTACCAGAAAATGTCTTACAGATGTCATTCTCAGTAAGCATGTGAGTTCATCTCATACTTGCTTCAACTTCATTGATTGTTATCAGTGTCACTACTGCAATGAAGTGTTACCCTCGTATACAGAACTGAAGTCTCATAAAATACACTTTCACCCGGAGATGAGCGGCTCTCAACATGACTGCAGTAATCAAATAATCGCGAATCAAACTACTGAAGCACCTGAAGACATTGCAAACACTTTTAGCTGTACTATTTGTGACACGAAGTTCGAATGcttggaaaaattgaaatatcattccATGGCATACTCGACCGAAGGCTTGTACAATTGCCATGTTTGCAACCGTCATTTCCCAAAGCTAAATCACCTAGAGGTCCACATGTTGAGACACACGAATTTGCACTTCATTCTATCTAAATATCACTGTCCCGTGTGTCGCGAAGGATTCACAAATCAGGTTAATGTCCGGATGCACGTGATGCACTTACACCCAAGCACGCCAATAGAGAAACCATTAACCAGTGATgctcaaaatacacaaaaaTTCAACTAG
Protein Sequence: MARVYVYERPVDAVSTNESFYEKLNYVTTALQIKQEPISTDDNCQDSTLPLADINTNTTTVTGETIVRETQLWNNVNNQENELVLSKYRNDTDLSGTNVVNTQKRKCLAFENFEVSEKKLGVGLKSPESIEATIESDVCFLNFKSLMASKVHTDYQTDGALPFCNKYHTICKSAHFLDEQKWMRRCKIKTKVSFCCRFCTAKYRTKSNLKCHVFHNHSKLLPFSAEKADNHSETDKSSKIKKIKTDETNETDKLSEYCETRETREIDKTSKMQLTENTDNYVTSPSVHQNGNDKIDPTPTKMKQTTITQFLSEYTRITEDFCPNKVRNPKKTLKKVIPRQNKTLTEKIDHCVETPKIAIPSQMKTILEASEPQGEGRRKIVTRRSGTTREKVNLHLKTQKITRQSGTVVKSLSTLTNEKTLITTESSTPNGSTTEENSSFVKIHIGCDMMKALLNKIIKTELKAEPCHFALENHNLQRVTRSSLRRSLNDLNTTPVIKSPKRIRFRKRAASTPKEKAEHQSTEKELRAKFKCKNLKVNLVRCDMVVKTETVDVTQISVEGDEKIAEMWQKKVTLNRENAPLVKVNELIKVEVKEPFLCSEVSNAHRDNTKANSRILFRCKACKKCFPIKKNLRKHFELRHVFFKSSICDAKCKTKFELQKHYMNKHSGFKRMQCCVCFKKFSSLVMLKQHLILHCTQVLLPKRKKQCIKEVIKCRMPDKKCSCKACGKRFWLKSCLKEHQKLCTKMRGREKQSQNVSNTVETSTKRVLDDANIKLNAPQSKLCLINEYSNGAISPPMKQTKMLLRGTTFAKGYTIDYSGVNKNTFDCTTCNKHFRTFRNLCMHEQTYSKAATHVCTICNTAFSTRTLLHRHHQFTHTFKTLTKHKYFCTFCTQGFRKKMKIQIHTRHFHAGDTPIIPIPWLECTEDWEVSTICSVCKLEFNSSEQFIQHNMFYYKGQIFTCAFCSKTFQGLYMLHSHIKSEHNTEDVKKQYTFTCDICNEGFIIESHCHAHKLHVHSMLHESSQYLQDHAYVSAANGMESTNGPIPKYNCNICHMIFIAEEDLRQHKMEYTNDGNYFCSFCTRKCLTDVILSKHVSSSHTCFNFIDCYQCHYCNEVLPSYTELKSHKIHFHPEMSGSQHDCSNQIIANQTTEAPEDIANTFSCTICDTKFECLEKLKYHSMAYSTEGLYNCHVCNRHFPKLNHLEVHMLRHTNLHFILSKYHCPVCREGFTNQVNVRMHVMHLHPSTPIEKPLTSDAQNTQKFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -