Basic Information

Insect: Megalopta genalis
Gene Symbol: -
Assembly: GCA_011865705.1
Location: NW:246-5760[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00011 0.006 16.1 0.7 2 19 466 483 465 487 0.89

2 8 1e-05 0.00056 19.3 4.2 1 23 493 515 493 515 0.98

3 8 0.0001 0.0054 16.3 0.1 3 23 523 544 521 544 0.94

4 8 0.13 6.7 6.5 1.8 1 23 551 574 551 574 0.98

5 8 2.8e-05 0.0015 18.0 0.7 1 23 578 600 578 600 0.97

6 8 0.00039 0.021 14.4 0.5 1 23 606 628 606 628 0.98

7 8 5.4e-05 0.0029 17.1 2.3 1 23 634 656 634 656 0.96

8 8 1.8e-06 9.5e-05 21.8 2.7 1 23 661 683 661 683 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00011	0.006	16.1	0.7	2	19	466	483	465	487	0.89
2	8	1e-05	0.00056	19.3	4.2	1	23	493	515	493	515	0.98
3	8	0.0001	0.0054	16.3	0.1	3	23	523	544	521	544	0.94
4	8	0.13	6.7	6.5	1.8	1	23	551	574	551	574	0.98
5	8	2.8e-05	0.0015	18.0	0.7	1	23	578	600	578	600	0.97
6	8	0.00039	0.021	14.4	0.5	1	23	606	628	606	628	0.98
7	8	5.4e-05	0.0029	17.1	2.3	1	23	634	656	634	656	0.96
8	8	1.8e-06	9.5e-05	21.8	2.7	1	23	661	683	661	683	0.96

Sequence Information

Coding Sequence: atggagctAGGGGAGGGAGAGGCGCAGATTTGTCGACTTTGCGGCCAGTATGAAAGCATATATATCGATGTGTTCAGCGAAGAAGGCACCAAGAGATTTTTAGGCTTGAAGATTCATTCGAAAATCAACATTCTGATAGATGAGAGGGATCCTCTGCCCAAGGCGATCTGTGTTCAGTGTCTGGGCAAGCTCGAATTCGTTTGCGACTTCCAAGAGGAGTGTCTTCGCACCCAACAAGTGTTACGCGATCGATACAATCTACCACCCCTAACAGAGATTGCCGAAGTAAAGACTGAAGAAACAACACCGAGCACGTCAACgaacaataacaacaacgacATCGACAAAAATCTTAATCCTCCAGCCAAGGAAAGCGTCAAAGAAGTAGCACAACGTGTTTCGAAAACAACAGCGAAGACTCAGAGAAATTTACGCAGTCAACATCAACAAgcgaataatagtaatagtaacaacaacggtaataataataataataataataataataataacaatagtaacaatagtaacaaCGAAGCTACTAAAGATCAAACCACCGATCAAAGCACAACGGAGGATAACACAGAGAATATACAAATTGTACAAAGCACCGAAACAACTCCCACGAGATGGTTGAGAAGTAGGCAAAATACAGATACAACTTCCACGAACGAGGTAACAACCGACACACCGATCGCGAACAGGCTTAGGAGTCATGGTAATACCGGTGCGGAAATAAGCGTGAGCCGCGAAGCGGGAAAGCAACAAGATCCGAACACCATACAAATTCCAACGTCGGCTTTAAACAAGCTTCTGACCATCGTATCGAACTCGCCGAACATAGAAGTGTCCGCGAAGGAATCGAGGAACCAAAGCAACGATACAGAAGATATCAGTTTCACGGTAGAATTATGTAAAAAGGAGAGCGACGATGTTGCGACGGTACGAGCCAGAGTATTTCCAGACCAAGGCTCGTGTTTAGTAGACGAATCTATCGTTGGTCTTCTACAGAATCAAAGTTGCGTAGAAGTGAATAGTATAATAAACACTATTATCAACAGCAGTTTGAAGAATGGTAATTCAACAAAGTCGAAGGACTCTGCCGAATTCGAGCAAAAATGGCAAGCTTCTCAGAATCCGGAAGAATTGTTTAAGATCGATGGAGAGGAAATTCGCGTGGACGACAACGTCGAACATATCGTAACGGATAATCAAAACGGTTACTCGTGTAAGCTGTGCTGCAAATTCTACGAACGCAAAGACAAATGTATGGTTCATGTGAAAACGCATCTGGGGATTAAGCAGTACACGTGTATTTTATGCAATGCCAAATTCGTATGCAAGTCCGACGTGATGAAACACATACGTTGTTCGCATACCAATCCTAGACCGATACAATGCCCGAAATGTCCAAAGAGGTTCAAATCGAAATTTTACTTGATGGAGCACGACAACGTGCACAAAGGCGTGAGGCCGTATTCTTGCACGGATTGCGGGCAAAGTTACCATCACAAAGTATCGTTGCAGATACACATGAAATCACATTTACCCCCGCAGAATTTGGCTTGCGAGTATTGCGGCAAAGTGTTCCCGTATCGTACGAGATTGTTGAGTCACATCGCTAGCGTTCATCTGAAAAATCGTCGGAATTTCAGGTGCCGATTTTGCTATAATCTCTACTCGAGTCTTTCAGTTTTAAACGAACACATCAAGACGCGTCACGCGACTACCTACACTTGCGAGGTGTGTAGCAAAACGTTCAAAGTTGCGTCGAAATACAAAGCTCATGTTTTGCAGCACACCAATCCTAAGCCTTTTGTATGCAACATCTGTAACAATAGATACGCGTCGAAAGCATTCCTGAACGAACATCTACTGAAACACGAGGGGTTGAGAAAACATATCTGCCAAAAGTGTGGCGCGAGATTCGCCCAAGCTAGTCACTTGGCCGCACATCGGCACGTGCACGGCGAAAAGAAACACGCCTGTCCGGAATGCGGGCGAAAATTTAATAGGCGTGACAACATGAAGGTGCATAGAAAAAGACATTTTGAGGATAAAAAGACTGGTATTATTAAACAGCAGAATGCTGGCGCGAACACGATTTCCACCGTGTCCAACGAAAAATAA
Protein Sequence: MELGEGEAQICRLCGQYESIYIDVFSEEGTKRFLGLKIHSKINILIDERDPLPKAICVQCLGKLEFVCDFQEECLRTQQVLRDRYNLPPLTEIAEVKTEETTPSTSTNNNNNDIDKNLNPPAKESVKEVAQRVSKTTAKTQRNLRSQHQQANNSNSNNNGNNNNNNNNNNNNSNNSNNEATKDQTTDQSTTEDNTENIQIVQSTETTPTRWLRSRQNTDTTSTNEVTTDTPIANRLRSHGNTGAEISVSREAGKQQDPNTIQIPTSALNKLLTIVSNSPNIEVSAKESRNQSNDTEDISFTVELCKKESDDVATVRARVFPDQGSCLVDESIVGLLQNQSCVEVNSIINTIINSSLKNGNSTKSKDSAEFEQKWQASQNPEELFKIDGEEIRVDDNVEHIVTDNQNGYSCKLCCKFYERKDKCMVHVKTHLGIKQYTCILCNAKFVCKSDVMKHIRCSHTNPRPIQCPKCPKRFKSKFYLMEHDNVHKGVRPYSCTDCGQSYHHKVSLQIHMKSHLPPQNLACEYCGKVFPYRTRLLSHIASVHLKNRRNFRCRFCYNLYSSLSVLNEHIKTRHATTYTCEVCSKTFKVASKYKAHVLQHTNPKPFVCNICNNRYASKAFLNEHLLKHEGLRKHICQKCGARFAQASHLAAHRHVHGEKKHACPECGRKFNRRDNMKVHRKRHFEDKKTGIIKQQNAGANTISTVSNEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00217956;
90% Identity: iTF_00183483;
80% Identity: -