Basic Information

Insect: Megalopta genalis
Gene Symbol: ZFX
Assembly: GCA_011865705.1
Location: NW:3953214-3961622[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.96 51 3.7 0.1 3 23 15 35 14 35 0.94

2 15 4.5 2.4e+02 1.6 4.2 1 23 881 904 881 904 0.80

3 15 0.00063 0.034 13.7 2.2 2 23 988 1010 987 1010 0.96

4 15 0.011 0.61 9.8 0.1 2 23 1023 1044 1022 1044 0.97

5 15 1.4e-05 0.00073 19.0 2.3 2 23 1047 1068 1046 1068 0.97

6 15 0.0096 0.51 10.0 0.3 1 23 1074 1096 1074 1096 0.95

7 15 1.9e-05 0.001 18.5 4.5 2 23 1103 1124 1102 1125 0.95

8 15 0.084 4.5 7.1 3.7 5 23 1138 1156 1137 1156 0.97

9 15 1.7e-05 0.00091 18.7 1.5 3 23 1163 1184 1162 1184 0.97

10 15 0.0078 0.41 10.3 0.3 2 23 1200 1220 1199 1220 0.97

11 15 5.1e-05 0.0027 17.2 0.7 1 20 1226 1245 1226 1248 0.92

12 15 6.4e-05 0.0034 16.9 2.7 1 23 1256 1278 1256 1278 0.99

13 15 0.0018 0.095 12.3 3.2 1 23 1284 1306 1284 1306 0.97

14 15 3.2e-06 0.00017 20.9 3.9 1 23 1312 1334 1312 1334 0.99

15 15 0.0011 0.06 13.0 6.3 1 23 1340 1362 1340 1363 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.96	51	3.7	0.1	3	23	15	35	14	35	0.94
2	15	4.5	2.4e+02	1.6	4.2	1	23	881	904	881	904	0.80
3	15	0.00063	0.034	13.7	2.2	2	23	988	1010	987	1010	0.96
4	15	0.011	0.61	9.8	0.1	2	23	1023	1044	1022	1044	0.97
5	15	1.4e-05	0.00073	19.0	2.3	2	23	1047	1068	1046	1068	0.97
6	15	0.0096	0.51	10.0	0.3	1	23	1074	1096	1074	1096	0.95
7	15	1.9e-05	0.001	18.5	4.5	2	23	1103	1124	1102	1125	0.95
8	15	0.084	4.5	7.1	3.7	5	23	1138	1156	1137	1156	0.97
9	15	1.7e-05	0.00091	18.7	1.5	3	23	1163	1184	1162	1184	0.97
10	15	0.0078	0.41	10.3	0.3	2	23	1200	1220	1199	1220	0.97
11	15	5.1e-05	0.0027	17.2	0.7	1	20	1226	1245	1226	1248	0.92
12	15	6.4e-05	0.0034	16.9	2.7	1	23	1256	1278	1256	1278	0.99
13	15	0.0018	0.095	12.3	3.2	1	23	1284	1306	1284	1306	0.97
14	15	3.2e-06	0.00017	20.9	3.9	1	23	1312	1334	1312	1334	0.99
15	15	0.0011	0.06	13.0	6.3	1	23	1340	1362	1340	1363	0.96

Sequence Information

Coding Sequence: ATGGATCTTACCAACAATGGAACATCGGGGGGTGCAGTGGCTTGTCCTGTTTGTACCCTCTATTTACGCGAGGGTATCAGTTTGCAAAGACATTTGGACACACATCCAAAGGAACAAGTCATCGAAGCTCTTATCAAAGCCAGTTCTAATTCCTCGCAATCACCACAAAGTCAGCTATCACCGTCTGCGCCTCCAACTTCTCCATCTGTACAATCACCGCAGAGTACACCACCAGTTTCACAGAATACTCATCTGTCAACTCAATCACCATATCCTATAGGACCAATCTTTGAATGTCCACCGATCGGTACTGTGATGCCACCTCAATTTGCTTCGTTCAGTTATCAACAGTTCGTGAACAATGGCACTATGATGATACCGCAATATGCAATGGCTCCTCAAGCTAATCAAATGATGCAGATGCTGTATAATCCTTATGGTATGTATCAGCAACAACAAATACCAACTGTTCAGATGATCTCACCAGTTACAACTATACCTAATACAACTAGAGGCAGGTCAATAGTAACTATGGCAGGCGAAACAAGTGGTAGGACTGCCATTGCTATACCTGTAAATAATTCCGAGCCAAAACAAATCTTACCTGAGATTTTGCCCGAATCAGAACAGGAATCTGAACAAGTGTTACCAGATATTAATCTTCCAGTTTCACCTCCATCGttaatcgaagaaaattctatTCATCAAAATGAAAGTGAGACCACTACAATTCAAATAGAAACTGAAGAACAGGAGTCCACTACATCGGATAGTGAAAATCGACACATTATTCAAAATGAATATGATAACATTCCAAGAACATTGGCAATCACTTGTAATGTTGAGGATGATAAAGTTGAAAGTGTGTTGCCTGATATCGATGAGGGCGAAACTTCATGTGTTGTTACTGTAGATGTTCAATGTAAACCTATGCAATACGAATCCTCGAGTGTACAAGAAGAATATGTGCACATATATAAAGATGaggaagataataataaagataatatgcCTGAAGTACCATTAGTGACATCAGCGAAGGAATTTGAAGAGACAACTACAGAAAAAGTTCCTTGCACAGAAGTAAATGAAACTGAAGGTACTTCGTCTGAAATACCCACAGAAGGTGTAACTAAAGATCCAGCTCAACCTGAAGTAGAACAGTTAGAACGTCTTTTAATCACTATTATGGAAAATGAATTTGATACTGAGTCACATAAAAAATCTGCTAATACAGATGACAAGAAGAAAGAGGACGATCCAAAAGAAGATCCACCCTCTTCTCCCCCAGAAAGGGCAGAAAGTGTGATTCATGAAACAGCAGTTAACAGTTCCAGtgaatttgaaaacaattgtaAATCCAGTATAGAACTAAAAATTAGTGAAAGTTCAGAAATTGATGTAGATagtaaagaagataaaaatttgtgtcTTTCATATCGTTATAAGAACAGCTTGTCTGCACCTGTATCACCTATGCCAACAGACAGTCGTCGTTCAACCTACTCTGTACGTTCAGTATTTGGTTCACATGAGAACCTTAATTCTTACCCAGTTGGTTTCGATGCAAATACATTGCAAgacgaagaaaatgaagatgagaaaaatgaaacacAAGACAACTTTGATGAAGCAGATATGGAAATAGAAGAAATTCAAAGTCCTCATACACCTTTCATTAAATATGGAGAAAATTCAGATAATGTTAGATCACATACCCCATTATCTGTGAGCAGTGGTATTTCTGTATTAAGGGTGAGAAAGGATCTCAGTAAACCATGTTCACCGGCTTCAGTGCATTCATTTTGTCATATAGATAATGGTATAAGCCATGATGAAGAAAGTAATATAGCAATGGATGCAACACCAGAGAAAGATCCTATTGATTGTTCTTCTATGGAGCAAGATGTAAAAGCAGATCAATCAGAAATCTTTTTGAATGAAACTGTTGAGAAGAAAATGGAAGGAAATTCAGCATATCAATCTGTAATAACTGAACATGTGAGCTCATTTCCCACAATTTCACAACAATCAACATCATCATCGCATGAACAATATTCTAGTACACCAAATAAAAGTAATCTTGTAAATCTGTCAGAATCTATAGCTGTTGCAAGTAGTTCTGATTCAAAGAGTTTCCATTCTTCTAAATCAATTATACAAAAACCATCAATGGAACTACTTAGTTTAAATGAAGATGCCCATGCAGGTCCAATGAATGTTTTTGAATTTGATGGGCTTCACATCTTAGTTCCTAGTACATTTATAAGTGATTCTTCTCAAAAAGCTGTTAGTGCAACGAGTCAGCAATCTATGGCAAGCAGTGAAGGTGGAATAGGTATAGATGAAGAAGTAAAGAGTGTTAATATGAGAGCTGATGAAACTATGCCACCTAGAGGTGAATTATCAGAACAGGAAAGCAATGGATGCACCGAACCGTCTGCTTGGCAGCTGTATGCTGGTCAGGAGTCATCACGTATGTCTACTTCTTATGACTTAATGGCCCGTGAGAGTTGGGAAGAATCTGAAGGATCAGACAATGAAATTAGTGGACCGTTATTAGACAGTAGATCATTAGCTACACATTTCACATCAAGTCTGTTCCTAGATCGAGACAGAAAAACTCCAACAAAACGAACATTCAAGTGTTACCATTGTCCCGAGGTTTTTGATTGTCCAAAAGAACGCAGAGTACATAGTACTACTACGCACAAAGAAGCTGGACCTAGTGGTAGCAGAGATTCTACAGATCAACCTGAGGTGAAAGATATCAAATTGCTGGATGGCCGCATGAACGCATTTGAGGAGATTTTTGTACCAGGTTTACATGTTCAACAAGTTTATCATCAACAGCCACTATTACATCAACTGCAACCACCGCAATCTTTGGATGTAACTGCAAAAGTAGAACCTGATCAAAAGATTGAAACTTCTTTAGTGTTACCGTCAAACATTGAGGTAGTTTGTACCCTGTGCAATCAACGATTTAGTAGTGAAAAATCGTTACAGCTACATCATAAAAGAGTACATCTCACAGAAACGTCAAAACGAGTTCGTGATAGTACCAAGTGCCAGATATGCCAAGAAGAGTTTCCCTCAGTTTTGTTGTTCAATGCACATCTTAAAATACATCCATTAGAGTGTGGTCAATGCGGGAAGTATTTTTATAGGAAACAGAACTTCAAGTTACACATGAAACGACATTTAGGGATAAAACCGTTCCCATGCACTGTTTGTGACAAagcatttttaacgaaacagAAATTGGATGAGCATACCAACGGACATACTGGAAATGCACCCGTTAAATGTAATCTTTGCAATGAAACATTTCGTAGATATTCAAATTTGACTCAACACAAAAATAGACATCATTtaaacataaaaagaaaattgaaggaTTATATATGTCACTGTGGCGAGGTATTTCATACGAAGAAAAAATTGGCTTGGCATAAGGAGACACACGACGACAAGCCCAAAGCGTGTACGTATTGCAATGAAAGATTTATTCATATGGCTAGCCTGACCAGACACATGCGTCGTGCTCACAACAGAAGATTCGTTCCGGATGCTCAAAGGGAGAGCGAAAACGTTGAATGTCCTATATGTAAGTGTATTTATTTGCGATCTTCCTTAGCAGTACATATGCGAGTACATAACGGGGAGAGACCATATGAATGTCAAGTTTGCTCCAAGGCGTTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACACACGCTGCCCGTAGCACCAAACCTTTCAAGTGTAATCAGTGTAGTGCCGCATTTTACCGGCACAGCGATTATACCGCTCACATGAATTCACATAGGAACGTGCGTCCTTATACCTGCAACTATTGCGGAGCGCAGTTTATACGAAAGTATAATTGTCTAAGGCATGTCAAAGAGCACGAAGAGAATAAAGCATACACGTGCGATGTTTGCAACAAAACATTTCATAGATCGTACTATCTGAAGGAGCACTTGCGAGTACACTCGGGCGCCAGACCATATACATGTCATATTTGCGGGAAATCGAGCGGTACGAAGTCGAACCACAACAAGCACGTTAGGATTCATCATGCGCGAGAACCTGTAAATACCGAAAactaa
Protein Sequence: MDLTNNGTSGGAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASSNSSQSPQSQLSPSAPPTSPSVQSPQSTPPVSQNTHLSTQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTTIPNTTRGRSIVTMAGETSGRTAIAIPVNNSEPKQILPEILPESEQESEQVLPDINLPVSPPSLIEENSIHQNESETTTIQIETEEQESTTSDSENRHIIQNEYDNIPRTLAITCNVEDDKVESVLPDIDEGETSCVVTVDVQCKPMQYESSSVQEEYVHIYKDEEDNNKDNMPEVPLVTSAKEFEETTTEKVPCTEVNETEGTSSEIPTEGVTKDPAQPEVEQLERLLITIMENEFDTESHKKSANTDDKKKEDDPKEDPPSSPPERAESVIHETAVNSSSEFENNCKSSIELKISESSEIDVDSKEDKNLCLSYRYKNSLSAPVSPMPTDSRRSTYSVRSVFGSHENLNSYPVGFDANTLQDEENEDEKNETQDNFDEADMEIEEIQSPHTPFIKYGENSDNVRSHTPLSVSSGISVLRVRKDLSKPCSPASVHSFCHIDNGISHDEESNIAMDATPEKDPIDCSSMEQDVKADQSEIFLNETVEKKMEGNSAYQSVITEHVSSFPTISQQSTSSSHEQYSSTPNKSNLVNLSESIAVASSSDSKSFHSSKSIIQKPSMELLSLNEDAHAGPMNVFEFDGLHILVPSTFISDSSQKAVSATSQQSMASSEGGIGIDEEVKSVNMRADETMPPRGELSEQESNGCTEPSAWQLYAGQESSRMSTSYDLMARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCYHCPEVFDCPKERRVHSTTTHKEAGPSGSRDSTDQPEVKDIKLLDGRMNAFEEIFVPGLHVQQVYHQQPLLHQLQPPQSLDVTAKVEPDQKIETSLVLPSNIEVVCTLCNQRFSSEKSLQLHHKRVHLTETSKRVRDSTKCQICQEEFPSVLLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKRKLKDYICHCGEVFHTKKKLAWHKETHDDKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00183443;
80% Identity: -