Basic Information

Insect: Megalopta genalis
Gene Symbol: ZNF236
Assembly: GCA_011865705.1
Location: NW:926-9256[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00078 0.041 13.5 0.6 2 23 165 186 164 186 0.96

2 26 8.5e-05 0.0045 16.5 1.1 1 23 192 214 192 214 0.98

3 26 1.2e-06 6.2e-05 22.3 0.7 2 23 220 241 220 241 0.97

4 26 0.0041 0.22 11.2 0.4 3 23 249 269 247 269 0.96

5 26 7.3e-05 0.0039 16.7 1.1 2 23 280 301 280 301 0.98

6 26 6.1e-07 3.2e-05 23.2 1.1 1 23 322 344 322 344 0.99

7 26 1.5e-05 0.00079 18.9 0.5 1 20 350 369 350 372 0.95

8 26 1.4e-05 0.00076 18.9 0.3 1 23 378 401 378 401 0.95

9 26 0.00026 0.014 14.9 3.6 1 23 410 433 410 433 0.98

10 26 1.5e-06 8.2e-05 22.0 2.1 1 23 560 582 560 582 0.98

11 26 0.00026 0.014 15.0 3.3 1 23 588 610 588 610 0.99

12 26 0.0048 0.26 11.0 4.8 1 23 616 638 616 638 0.98

13 26 0.004 0.21 11.2 6.7 1 23 738 760 738 760 0.98

14 26 3.8e-05 0.002 17.6 4.8 1 23 766 788 766 788 0.99

15 26 0.00017 0.0091 15.5 0.8 3 23 796 816 794 816 0.97

16 26 0.00033 0.018 14.6 7.6 1 23 822 844 822 844 0.98

17 26 0.037 2 8.2 1.8 2 23 1207 1228 1206 1228 0.96

18 26 0.00048 0.026 14.1 1.2 1 23 1234 1256 1234 1256 0.98

19 26 0.00066 0.035 13.7 1.4 2 23 1263 1284 1262 1284 0.97

20 26 7.6e-07 4.1e-05 22.9 1.6 2 23 1355 1376 1354 1376 0.98

21 26 0.00023 0.012 15.1 3.5 1 23 1382 1404 1382 1404 0.99

22 26 0.0002 0.011 15.3 1.9 1 23 1410 1432 1410 1432 0.98

23 26 0.00042 0.022 14.3 2.6 1 23 1438 1460 1438 1460 0.98

24 26 4e-06 0.00022 20.6 0.6 2 23 1697 1718 1696 1718 0.97

25 26 0.00036 0.019 14.5 3.6 1 23 1724 1746 1724 1746 0.98

26 26 2.4e-07 1.3e-05 24.5 1.6 1 23 1752 1775 1752 1775 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00078	0.041	13.5	0.6	2	23	165	186	164	186	0.96
2	26	8.5e-05	0.0045	16.5	1.1	1	23	192	214	192	214	0.98
3	26	1.2e-06	6.2e-05	22.3	0.7	2	23	220	241	220	241	0.97
4	26	0.0041	0.22	11.2	0.4	3	23	249	269	247	269	0.96
5	26	7.3e-05	0.0039	16.7	1.1	2	23	280	301	280	301	0.98
6	26	6.1e-07	3.2e-05	23.2	1.1	1	23	322	344	322	344	0.99
7	26	1.5e-05	0.00079	18.9	0.5	1	20	350	369	350	372	0.95
8	26	1.4e-05	0.00076	18.9	0.3	1	23	378	401	378	401	0.95
9	26	0.00026	0.014	14.9	3.6	1	23	410	433	410	433	0.98
10	26	1.5e-06	8.2e-05	22.0	2.1	1	23	560	582	560	582	0.98
11	26	0.00026	0.014	15.0	3.3	1	23	588	610	588	610	0.99
12	26	0.0048	0.26	11.0	4.8	1	23	616	638	616	638	0.98
13	26	0.004	0.21	11.2	6.7	1	23	738	760	738	760	0.98
14	26	3.8e-05	0.002	17.6	4.8	1	23	766	788	766	788	0.99
15	26	0.00017	0.0091	15.5	0.8	3	23	796	816	794	816	0.97
16	26	0.00033	0.018	14.6	7.6	1	23	822	844	822	844	0.98
17	26	0.037	2	8.2	1.8	2	23	1207	1228	1206	1228	0.96
18	26	0.00048	0.026	14.1	1.2	1	23	1234	1256	1234	1256	0.98
19	26	0.00066	0.035	13.7	1.4	2	23	1263	1284	1262	1284	0.97
20	26	7.6e-07	4.1e-05	22.9	1.6	2	23	1355	1376	1354	1376	0.98
21	26	0.00023	0.012	15.1	3.5	1	23	1382	1404	1382	1404	0.99
22	26	0.0002	0.011	15.3	1.9	1	23	1410	1432	1410	1432	0.98
23	26	0.00042	0.022	14.3	2.6	1	23	1438	1460	1438	1460	0.98
24	26	4e-06	0.00022	20.6	0.6	2	23	1697	1718	1696	1718	0.97
25	26	0.00036	0.019	14.5	3.6	1	23	1724	1746	1724	1746	0.98
26	26	2.4e-07	1.3e-05	24.5	1.6	1	23	1752	1775	1752	1775	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACACGATAATCGCAGAATCTAATCCGGCCGCAACGGTGCCAATAAATATTGTTGCTACCGAAGATGGTCGAGCGTTATTAGCAATGACAGAAGACAAAGATGGTCTATTGGAAGTTATCGCGACCCCGGTTACGCTCATTGGTCATAATGGTACAGCTATGTCGTTGATGGATGTCAAGAATCTTAATAGTTGTTTGATATTACAACCGTCTCCTTTCCAAATCAATTTGGACAATGGCGAGAGTTCAGAACTTGAAAGATCCAAGCAAATTCTCCAAGTTGATCCCAATGTTCCTCAACGAATCAAAACCAGAGTAGATTTAGATACGATGCATCATTTCCTTGATAACGAATCCTTGCAGCAagagaaaatcgatgaaatttctAAAGGGAAATCAACAGGCATGATTACAAAACCAAATAGTCCTGGACGACCCAAAAAGAACAGTGCTATTTCATTGAAAGGGAAAGAAAGTTTAAGATGTGACATATGTCAACAAGAATTTACGAAGCAAGCACCATATAGAAAGCACATGGAGAATCATGCCGAAGAAAAGCCACACCGCTGTCCAAAATGTTCAGCATCTTTCAATGTACCGACCAACTTTACGCTTCATATGGCTACACATAATTCTGGTGATCCAAAATGCCCGGAATGTGGTAAAAAATTTACAAGAATGGCCAGCTTGAAATCTCACATGTTGTTAcatgaaaaggaagaaaatttgTTCTGTACAGAGTGTGAAGATGTTTTTTCAACTAAAacTCAATTAGATGCACATTTGAAACTTCATGGAGAAAAGTGGACAACGGAAGAAGCCAGAAAATGTAAACTGTGCAATAAACAGTTCAGACAACCGGCACTGTATCGACTTCATATTCGTGAACATTACAGATTGCAGACAAAGGTAGTAAAGCAAACGAAAAGAGGAGCAAAACATAAAACAGTGTACAAATGTACAATATGCTTAAAGTCCTTCCAAAAGCCGAGCCAATTAATGCGTCACATTCGAGTGCATACGGGTGAAAAACCTTTTAAGTGTACGGTGTGCGGGCGTGCATTCACGCAAAAAGGTTCCTTGCAAATTCATACGTGGCAGCACAACGGTATACGACCACATGCTTGTGAACTCTGTGATGCCAGGTTTAGTCAAAAAGGCAATTTAAATGTTCATATAATGAGAGTTCATAACGTACCAGAGGAAGAGCCTATATACAGGTGTAACTACTGTTCTTGCGTGTTTAAAAAGCTTGGCAGTTTAAACGGACACATGAAACGTATGCATACAGGAGTGAACGAGGACAGTGCCACCGTTAAAATCTCCCAAACAACAGACACCATGGAATCGGACATTCGGGCAACTGTGAACAACGTTATAACGCAATTGGCATCTTTGGAATCTAATACAGACGAAGTTGGAAAACCGGAAAATTCTGGAGAGAATGGATTGTTATCAAACGACCCTACCAAGAAAGATATTCTACAACAAGCTCTGAAAAATAGTGGACTACCTAGCAAAAACAAAACTTTTTACGACGGTTCAACGGAAACGAAAAAGTTGGATGCACGCACAAATTTTGTTACCTTACTGGACAGGGCACCGGACAGTGGTACTAGAAAATACTTGACAATAAAACAACGGTGTGTAGGAAATGTAAGATGGTACGCGTGTACCTTTTGccataaagaatttaaaaaaccaTCAGATCTGATACGCCATCTACGAGTGCATACACAGGAAAAACCATTCAAGTGCACGCACTGTTATCGTTCGTTCGCTTTGAAGTCTACCATGATAGCGCACGAACGTACACATACAGGTACCAAGAGATACGCCTGCAATTCTTGCGATAAAACGTTCACGTGCCACAGTAGCTTGATTATTCATACAAGATCCCATGGGAACTCGGACGACTGTTTTAGTATATCGATTGATAACGATAGCGGCGCTGGTATCGATCACGATAAAGATAGTGCTGATATTGATGCAACACACAACGTTGCCGCTCGTTCTAAtgatcgatcgaaaataaatgCAAGCAATAAGTCAAAAATGTCTCCAAAAACGGAGAATTTCGTATCTCAAGTGGTGTTGCAGGAGCCATTGGTAATCAGTGACTCCGGAAACAAGATATGCGTGGTGCAGATACCTTCGAAAAGATGTGTTTACGATGCAGCAGTCGATCCAGCTAGACCGCATAAATGTTGGGTGTGCCAAGCGGCATTTAGAAAAATAAGTCACTTGAAACAACATCATCGACGACATACTGGAGAACGTCCGTACAGGTGTTCCAAGTGCGACAGGCGATTCACGTCAAACAGTGTTTTGAAATCGCATTTGCACACACACGAAGACTCTAGACCTTATGGATGCTCCATTTGTACCGCGAAATTCTCTACGCAGAGTAGCATGAAAAGACATTTGGTTACTCATAGTAACAAACGACCATTCATGTGTCCATATTGTCACAAGACGTTCAAGACTTACGTTAATTGCCGCAAACATATGAAAATACATAAACACGAGCTGGCTCAACGGCAACTGGAACAACATAAACTTGGGTCCCAGGATGAGATTGCAAACAAATTGAATACAACGGAGAATTCTAGGCAAGAGATAACATCCGAATTTCCCTGCTGTTCTTCGTCTAATTTTTCTGCTGGTAACACTAACGATACTCCGCTTGTCACAACTGCGAGAACTGACGCCGACACTGTTGTCGCAACAACATCCACGTTTTCCGATAATCTTACACCCACTTCGGTTGACGTATCTTTTCAAGAACGAATGGAATCAAACTTTCCACAAACTTTTCCCCATCAATTCCAAGaaaatatgaCGGAAATAACTGTGACAAATTTAGAAAATCCACAGATGTTGCACATCGATGAAAGCGGATCGGTTACATTGCCAGTTTATTCAACTGATCAAGCTCTAACACCGGAGAGCATACAAGAAATCGAAGAAACATTGAACCAACAGCTTTTCAACATTGGGATGAACCTTAATTTGGGAAACGACCATTCAAAACATTCGTGCGATAATAGTGAATTGCAGAATATGAAACTACAACATCAGCAACCCGCGTTAAATGTCATTTACACGAGTAGTAACAATTCTAATAATGGTGCCAACACCGAGCAGTCTGGAGAGCAAGTGTTCGCGTCGCAACTAGATTCGTTCGAGATGGATCATATTACTTTACAACCGGAAACTGAAATTACACTAGATAATATTGGCCTCGATGCGAATAATTCGACGAGTATGGCAAGCATATTGCCACAAACTGTAAAAGGAGAACTGTCGAATCAACTTGCCATTTCTGCTGTTTCGTCTGAGAATTTGACCGATAGTCACCAAGCAAGTAGGTACATGCAGACCGTGTTGTTAATTTCCGAGGAAAATCTTCCAGAAAAAGTAAATACAAGCAACCAACTGGAAATGTGTGAGGCCGAGAAGAATACGAATACAACGTTCTTAACAAAAGAATTTCGGAGAATGTCCAAGCTTTCGTCAAAGATTCAGAAAGACTCATTACCCTCCGAGATCTCTGAGAACGACGAAATCAACGCGAATCAATCCCCTCGAAGAGTGTCTCTGTTGCAGTGTCATATGTGTAGTCAGCAGGGATTCACAGCATCCAAGTTGAAGGAACACTTGAAGATCCATCGCGGGAAAAAAGAGTATCAGTGTACGGAATGCTCTTCGAGATTTTACACGAATGGTGGATTAAATAGGCACTCTAAGATACATACAAATAAACAGCATTGGAAGTGTTCATcatgcgaaaaatattttgctaATAGAACGCAATTGCGATCGCATAGCAGAGTTCACGAAAGCTTCTCGTGGAACGAGAAGGATGTTTCAATTTTGTCGCAAATACGGGCAACAGTAGATAACGAGTCATCATTGAATGATGTCGTGATAGATTCGGATTCAACTGTGTCTGAAAGAGTTCTGCTGGACACAGTTGCGGAACGGGAGGTAATGGATCGAGTAGAATATGTAGCAatggaaaaaaaggaacaaaaggAGTATacgaataaatgtaaattttgtcCAAAAACGTTTCGTAAACCAAGCGATCTCGTCAGACACGTCCGTACACACACAGGGGAGCGCCCATACAAGTGTGATTATTGCAATAAAAGTTTTGCTGTAAAATGCACCTTGGATTCTCATACCAAGGTTCATATCGGCAAAAAGACGTTTCGTTGCCATGTGTGCAGTAGTTTGTTCGCAACGAAGGGCAGCCTGAAAGTTCATATGCGTTTGCATACCGGTTCGAAACCTTTTAAATGTCCCGTCTGCGACTCGAGATTTCGTACCTCGGGTCACAGAAAAGTACACTTGTTGAAACACGCCCGAGAGCATAAAGGTACCTTTAAGAGGaaacagaaacatttaaaaGTTGCTGCCATTGCAGAAGTTGCTATGGCGGCTAATATTGGAAAACCTGACGACGCAAGGCAACAGAAGGTGTGCAGCTACGGAGAAGAACAAGAACAGCATAATCATCATTACGAGCAGGCGTCGCAAACAACAAATACAGAATACTCAAATTTACAAGCAATTAACGTCGAAACAACTGCTTCGTGTTTAACCGATCAAATCACCTTTGAGTCGGAAACGTCTGTCCCAAACAATAATTCGATACTATCCCTAAACGAAGGTAACCAATTGGTTGccaatttacattttcttttggCGAACGGTCTCGTTACCATACAGACCGAAGAGTCGTTACTACCGCAGCCGGTAGCGGCTGACAATACGTTGCATCAGCATTCGACCGTTACCGCCGATCCTGTCTGTacatcgataataaatatttcaccagAGATCACTAGCAGTGATCAGCAGCAAGGTATTGCTGTTAAAGAAGCTATTCATGCGGAGAGCACATTGAAAGCACAGCTATCATCTCCGTATCAATTAGAACCGAATAATTGTCTCTTAACTAGTATTGCAACGCCATCGCGGATAGAACAGTTTGGAAAGGCTTCATCCATTGAGAAATGTTTGTCAACAATAGAGAAATTATCCACCAAAGGAAATTCATCAAAAAAAGAGTGCGATGTTTGTGGAAAAACATTCACGAAACCGTATCAGGTTGAACGGCATAAACGAATTCACACGGGTGAACGTCCATACAAGTGTGATTTATGCATAAAGTCGTTCGCTCAAAAATCCACTTTACAAATGCATCAGAAACACCATACGGGCGATAGACCGTATCCTTGTCCACACTGTGAATATTCTTTCACACAGAAAGGAAATCTTCGTACGCACATGAGTCGCGTACATCGGCTAAATGCCATCGACTCGAAGAAAGTTAAACATAATCAGCAATCGTTGCAATTGCTACAACGCAAGTTTCCTCAGAGTAATCTGAGCGAGGTTAAAAGTCTGAATTTAGACGATATACCATTCATTGAATTTCTTAAATAA
Protein Sequence: MLTRHTIIAESNPAATVPINIVATEDGRALLAMTEDKDGLLEVIATPVTLIGHNGTAMSLMDVKNLNSCLILQPSPFQINLDNGESSELERSKQILQVDPNVPQRIKTRVDLDTMHHFLDNESLQQEKIDEISKGKSTGMITKPNSPGRPKKNSAISLKGKESLRCDICQQEFTKQAPYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNSGDPKCPECGKKFTRMASLKSHMLLHEKEENLFCTECEDVFSTKTQLDAHLKLHGEKWTTEEARKCKLCNKQFRQPALYRLHIREHYRLQTKVVKQTKRGAKHKTVYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTVCGRAFTQKGSLQIHTWQHNGIRPHACELCDARFSQKGNLNVHIMRVHNVPEEEPIYRCNYCSCVFKKLGSLNGHMKRMHTGVNEDSATVKISQTTDTMESDIRATVNNVITQLASLESNTDEVGKPENSGENGLLSNDPTKKDILQQALKNSGLPSKNKTFYDGSTETKKLDARTNFVTLLDRAPDSGTRKYLTIKQRCVGNVRWYACTFCHKEFKKPSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHTGTKRYACNSCDKTFTCHSSLIIHTRSHGNSDDCFSISIDNDSGAGIDHDKDSADIDATHNVAARSNDRSKINASNKSKMSPKTENFVSQVVLQEPLVISDSGNKICVVQIPSKRCVYDAAVDPARPHKCWVCQAAFRKISHLKQHHRRHTGERPYRCSKCDRRFTSNSVLKSHLHTHEDSRPYGCSICTAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQHKLGSQDEIANKLNTTENSRQEITSEFPCCSSSNFSAGNTNDTPLVTTARTDADTVVATTSTFSDNLTPTSVDVSFQERMESNFPQTFPHQFQENMTEITVTNLENPQMLHIDESGSVTLPVYSTDQALTPESIQEIEETLNQQLFNIGMNLNLGNDHSKHSCDNSELQNMKLQHQQPALNVIYTSSNNSNNGANTEQSGEQVFASQLDSFEMDHITLQPETEITLDNIGLDANNSTSMASILPQTVKGELSNQLAISAVSSENLTDSHQASRYMQTVLLISEENLPEKVNTSNQLEMCEAEKNTNTTFLTKEFRRMSKLSSKIQKDSLPSEISENDEINANQSPRRVSLLQCHMCSQQGFTASKLKEHLKIHRGKKEYQCTECSSRFYTNGGLNRHSKIHTNKQHWKCSSCEKYFANRTQLRSHSRVHESFSWNEKDVSILSQIRATVDNESSLNDVVIDSDSTVSERVLLDTVAEREVMDRVEYVAMEKKEQKEYTNKCKFCPKTFRKPSDLVRHVRTHTGERPYKCDYCNKSFAVKCTLDSHTKVHIGKKTFRCHVCSSLFATKGSLKVHMRLHTGSKPFKCPVCDSRFRTSGHRKVHLLKHAREHKGTFKRKQKHLKVAAIAEVAMAANIGKPDDARQQKVCSYGEEQEQHNHHYEQASQTTNTEYSNLQAINVETTASCLTDQITFESETSVPNNNSILSLNEGNQLVANLHFLLANGLVTIQTEESLLPQPVAADNTLHQHSTVTADPVCTSIINISPEITSSDQQQGIAVKEAIHAESTLKAQLSSPYQLEPNNCLLTSIATPSRIEQFGKASSIEKCLSTIEKLSTKGNSSKKECDVCGKTFTKPYQVERHKRIHTGERPYKCDLCIKSFAQKSTLQMHQKHHTGDRPYPCPHCEYSFTQKGNLRTHMSRVHRLNAIDSKKVKHNQQSLQLLQRKFPQSNLSEVKSLNLDDIPFIEFLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00184071;
90% Identity: iTF_00184071;
80% Identity: -