Basic Information

Insect: Megalocaria dilatata
Gene Symbol: ZNF526
Assembly: GCA_034642435.1
Location: CM067854.1:18935029-18935988[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0011 0.12 14.0 2.1 2 19 61 78 60 81 0.93

2 9 0.078 8.8 8.2 2.1 1 23 88 111 88 111 0.94

3 9 1.2e-07 1.3e-05 26.5 1.9 2 23 119 141 118 141 0.97

4 9 2.7e-06 0.0003 22.2 0.8 1 23 146 169 146 169 0.97

5 9 0.51 58 5.6 3.4 1 23 178 201 178 202 0.93

6 9 1.1e-06 0.00013 23.4 0.4 1 23 208 230 208 230 0.98

7 9 2.3e-06 0.00026 22.4 3.1 1 23 236 258 236 258 0.98

8 9 0.00011 0.012 17.2 2.2 1 21 264 284 264 287 0.94

9 9 8.3e-05 0.0094 17.5 1.8 1 23 293 315 293 315 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0011	0.12	14.0	2.1	2	19	61	78	60	81	0.93
2	9	0.078	8.8	8.2	2.1	1	23	88	111	88	111	0.94
3	9	1.2e-07	1.3e-05	26.5	1.9	2	23	119	141	118	141	0.97
4	9	2.7e-06	0.0003	22.2	0.8	1	23	146	169	146	169	0.97
5	9	0.51	58	5.6	3.4	1	23	178	201	178	202	0.93
6	9	1.1e-06	0.00013	23.4	0.4	1	23	208	230	208	230	0.98
7	9	2.3e-06	0.00026	22.4	3.1	1	23	236	258	236	258	0.98
8	9	0.00011	0.012	17.2	2.2	1	21	264	284	264	287	0.94
9	9	8.3e-05	0.0094	17.5	1.8	1	23	293	315	293	315	0.97

Sequence Information

Coding Sequence: ATGACTGAAAATCAGGAAAATGAAAACACGAAtgtaaaaatagaaataaaggAGGAGGAAATTGAAGAACACGTAACAACTGTCGAAAATAACAAACTAAAGAATACAAGGATAAAGGTGCCTTCGAAATATTCAAGCACGAAGAAGAAAGGCTATAGGAGAGATGATCCTAAAAAAATTCCatgtaaaatttgcaatagacgtTTTACTTTCAATCACCTGTTGAAAGTTCATTTTCATAACGACGCAGAGAAAAATGAGTTTAGATGCAGTCTTTGTGGTGATAATTTTTGTAGCGATTTGGACTTGAAGACACATCTGTCGGAAAAGCACGCAGAAGAGGCTTTGAAATTAAAGTGTGACCATTGTGGAAAAAGCTATACGTACGAAGGAGATCTGAACAGGCATATTAGAACCAAACATGaaggtttcatatataaatgtgAGCTGTGCGATAAGGCATTCAATAGAAGTCAAGCACTCGAAGATCATATTCATGTGAAACACGATGAAACTTACGTCAAACCTAAATTTCCTTGCGCTTCCTGTGATAAAATTTTCTCTTGTAAAAAAACGATGATGTTGCATGTCAAAAATATCCATCACGGACTACGACATTTTTTCGTTTGCGATATGTGTGGTAAGAGCCTGGCGACTCCTAACTCCTTCAGAAACCATCTAAGAACACATACTAAAGACAAGCCTTTCGAATGCTCCGTTTGCGGTAAAAGATTCGGCAGGAATCATCATTTGCAAGATCACCTTGTGACGCACACTAAGGAAAAGCCACACATTTGTTCTAGATGCGGGAAAGCTTTTACTCAGAGGGCGCCATTGTTGAGGCACATGAAGTGTGTTCACGAAACTGCTAGACCATACCAATGCCTCATATGTTCCAAGTCTTTTGCTACAAAATCTCTCGTTCATACTCATGCCAAATTGCATAACGTCATCAACTGA
Protein Sequence: MTENQENENTNVKIEIKEEEIEEHVTTVENNKLKNTRIKVPSKYSSTKKKGYRRDDPKKIPCKICNRRFTFNHLLKVHFHNDAEKNEFRCSLCGDNFCSDLDLKTHLSEKHAEEALKLKCDHCGKSYTYEGDLNRHIRTKHEGFIYKCELCDKAFNRSQALEDHIHVKHDETYVKPKFPCASCDKIFSCKKTMMLHVKNIHHGLRHFFVCDMCGKSLATPNSFRNHLRTHTKDKPFECSVCGKRFGRNHHLQDHLVTHTKEKPHICSRCGKAFTQRAPLLRHMKCVHETARPYQCLICSKSFATKSLVHTHAKLHNVIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01024304;
90% Identity: -
80% Identity: -