Basic Information

Insect: Megalocaria dilatata
Gene Symbol: -
Assembly: GCA_034642435.1
Location: CM067856.1:22759656-22761584[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00017 0.019 16.6 0.3 1 23 280 303 280 303 0.98

2 12 0.0075 0.85 11.4 0.1 1 23 309 332 309 332 0.94

3 12 0.00038 0.042 15.4 0.6 1 23 338 361 338 361 0.96

4 12 0.00069 0.078 14.6 0.3 1 23 367 390 367 390 0.96

5 12 0.0012 0.13 13.9 2.1 1 23 396 419 396 419 0.95

6 12 0.00015 0.017 16.7 0.5 2 23 425 447 424 447 0.96

7 12 0.13 14 7.5 0.2 1 23 453 476 453 476 0.96

8 12 0.0008 0.089 14.4 1.2 1 23 482 505 482 505 0.95

9 12 0.00032 0.036 15.7 1.4 1 23 511 534 511 534 0.93

10 12 0.041 4.6 9.0 3.0 1 23 540 563 540 563 0.93

11 12 0.00075 0.085 14.5 1.2 1 23 569 592 569 592 0.97

12 12 5.6e-05 0.0063 18.1 0.9 1 23 598 621 598 621 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00017	0.019	16.6	0.3	1	23	280	303	280	303	0.98
2	12	0.0075	0.85	11.4	0.1	1	23	309	332	309	332	0.94
3	12	0.00038	0.042	15.4	0.6	1	23	338	361	338	361	0.96
4	12	0.00069	0.078	14.6	0.3	1	23	367	390	367	390	0.96
5	12	0.0012	0.13	13.9	2.1	1	23	396	419	396	419	0.95
6	12	0.00015	0.017	16.7	0.5	2	23	425	447	424	447	0.96
7	12	0.13	14	7.5	0.2	1	23	453	476	453	476	0.96
8	12	0.0008	0.089	14.4	1.2	1	23	482	505	482	505	0.95
9	12	0.00032	0.036	15.7	1.4	1	23	511	534	511	534	0.93
10	12	0.041	4.6	9.0	3.0	1	23	540	563	540	563	0.93
11	12	0.00075	0.085	14.5	1.2	1	23	569	592	569	592	0.97
12	12	5.6e-05	0.0063	18.1	0.9	1	23	598	621	598	621	0.92

Sequence Information

Coding Sequence: ATGGGTGATAATGGATTATTTACAAATACTCTCTATTTCAGTGAACAGCCTGTAGAAGATGAGGAATTCCAAGAAAGCAGTAGAGCTGTAGAAACTGTTAATGGAAATACAGTTCGTAAAAGACATaaaaaatgtaaagttgaagtATCTCCTCGAAGAAGTGAGGCTAAGGATGAAAATATTGAACCTGTTGCAAATAAAGTTCGAAAGAAACCTAAGAAAAGTCAAGATGATGTATCATATCAAAGAAGTGAAGCcaaggttgaaaataaagtctCGAAAAAACATCTAGAGGATAAAGTGTCCTGTGATAGTAGTGAAGctgttgaaaattcaaaaactataGATGCAAATAAAGTTCGAAAAGAACCTAAAAAAAGTCAAGATGATGTATCATGTCAAAGGAGTAAAGCCGAGATTGTAAATAAACTCCTAAATAAACGTAAAAAATATCTAGAGGATGAAGTAACCTGTGAGAGTATCGAAGTTGATAGGTCTCATCAAAAAAGTGAAACTGAGGTTGAAAATATTGGAGTCCGCAAAAAACGTAAGAAACATTTGGAGAATGAAGTGTCCTGTGAGAGTGGTACAGGTAATGTTGAACATGCGGAAAGTGTGAAAGCAAGTAAAGTTCAGAAGAGACTCCCAGATGATGAAGTAACCTGTGAAAGCATTGAGGTTAAGGTTGAAGAAACTGTTAATACAAAAGAAGTTCAGGGAAGTACTAAGAAAAGCCAAAAAAGTGGAATCAATGTTGAATGTATTGCAAAGAGACTCCGGAAAAAACATAAGAAAGTTAATATTGAAAATGCTGAAACTGTGGATGCAAACGAAGAGTATCCATGTCATTTATGTGAATATGTTTCAGAACGTCCGGATGTTCTCAAAAGACATATAAGATCTGTTcatcaaaaactgaaaccatacGAATGTCGTTTATGTGATTTCGCTGCAAGTCGCAAAGATACTTTAATCACACACTTAGGTTCTATTCATCTTGATTTGAAACCATACAAATGTGACAattgtgattatgctgcaaatcatcaAGCTGATCTCAAAAGACATGTGGACAAAGTTCATAATGATTCCAAACAATATGCATGCCAGATATGCGATTACGTTACAAGTCTGAAAAAAAGTCTCAAAAATCATGTCGATACCGTgcatttaaatttgaggaaaCACAAGTGCGAAttttgtgattatgctgcaagtCGAAAAGATTACCTCAAAAAACACGTAGATTCGACTCATTTAGGTTTGAAAAAAGAATGCAGCTTATGTAATTATGTGACAGATAGGGAAAGTGATCTCAAACGTCACATAAATTCTATGCACGTGAATATTAAGCCATTTGAGTGTGACTCGTGCGATTATACTACATACCAGATGATTAATATGAAAGGACACATAGAATCTgttcattttaatataaaaagatttatgtGCCAACACTGTGATTACAAGGCTAATCGAAAAGCCGACCTTCAGGTGCATATAGATTCTCGTCATTTGAATGTGAACAAATTTTTGTGCGAACAATGTGATTACACAACTAATAgaaaagttgatcttaaaactcaTATCCGGTTTACCCATCTGAAAATAGAGCAACATAATTGTTGCTTGTGCGATTATTCCACCAATCGGAAAATTAATCTCGGTAAACATATCGATAATGTTCATTTCAAattgaaggaacataagtgtgaactatgtgattatgctgccaACCAAAAAGTCCATCTTATAGCACATATTAACTCCAAACATTTGAACTTGAAGGAACACCAATGTGAGTTATGCGGGTATGCTACAAATCAGAAAACGAATCTCAAAAGACATATAGGCTTGATGCATTTTGGTAAAGTGAAAATTGAGGGGAAGAAGAGAGAAAAAAACATCCAAGATTCACAtacagaataa
Protein Sequence: MGDNGLFTNTLYFSEQPVEDEEFQESSRAVETVNGNTVRKRHKKCKVEVSPRRSEAKDENIEPVANKVRKKPKKSQDDVSYQRSEAKVENKVSKKHLEDKVSCDSSEAVENSKTIDANKVRKEPKKSQDDVSCQRSKAEIVNKLLNKRKKYLEDEVTCESIEVDRSHQKSETEVENIGVRKKRKKHLENEVSCESGTGNVEHAESVKASKVQKRLPDDEVTCESIEVKVEETVNTKEVQGSTKKSQKSGINVECIAKRLRKKHKKVNIENAETVDANEEYPCHLCEYVSERPDVLKRHIRSVHQKLKPYECRLCDFAASRKDTLITHLGSIHLDLKPYKCDNCDYAANHQADLKRHVDKVHNDSKQYACQICDYVTSLKKSLKNHVDTVHLNLRKHKCEFCDYAASRKDYLKKHVDSTHLGLKKECSLCNYVTDRESDLKRHINSMHVNIKPFECDSCDYTTYQMINMKGHIESVHFNIKRFMCQHCDYKANRKADLQVHIDSRHLNVNKFLCEQCDYTTNRKVDLKTHIRFTHLKIEQHNCCLCDYSTNRKINLGKHIDNVHFKLKEHKCELCDYAANQKVHLIAHINSKHLNLKEHQCELCGYATNQKTNLKRHIGLMHFGKVKIEGKKREKNIQDSHTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00965402;
90% Identity: iTF_00965402;
80% Identity: -