Basic Information

Insect: Megalocaria dilatata
Gene Symbol: -
Assembly: GCA_034642435.1
Location: CM067857.1:6253911-6279703[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.00043 0.048 15.3 0.4 2 23 148 170 147 170 0.97

2 20 0.14 16 7.3 6.0 1 23 316 339 316 339 0.94

3 20 3.7 4.2e+02 2.9 0.1 6 20 350 364 348 366 0.93

4 20 0.11 12 7.7 1.1 1 20 372 391 372 395 0.90

5 20 0.0018 0.21 13.3 2.6 2 23 463 484 462 484 0.98

6 20 0.016 1.8 10.4 0.1 1 23 502 523 502 523 0.98

7 20 0.013 1.5 10.6 0.4 2 23 527 548 526 548 0.96

8 20 4.8 5.4e+02 2.5 0.8 2 23 575 596 575 596 0.95

9 20 2.6 2.9e+02 3.4 1.7 1 23 611 634 611 634 0.83

10 20 0.13 15 7.4 0.1 2 23 647 668 647 668 0.96

11 20 6.3e-06 0.00071 21.0 6.6 1 23 703 725 703 725 0.98

12 20 0.00091 0.1 14.2 2.1 2 23 742 764 741 764 0.93

13 20 0.00063 0.071 14.7 0.7 1 23 781 804 781 804 0.95

14 20 0.011 1.2 10.9 0.1 2 23 817 839 816 839 0.93

15 20 0.00071 0.08 14.6 0.3 1 23 857 879 857 879 0.92

16 20 0.018 2 10.2 0.0 1 23 906 929 906 929 0.90

17 20 0.0072 0.81 11.4 1.0 2 23 939 960 939 960 0.95

18 20 0.0012 0.13 13.9 0.8 1 23 973 996 973 996 0.97

19 20 6.6e-07 7.4e-05 24.1 1.1 1 23 1003 1025 1003 1025 0.98

20 20 0.00063 0.07 14.8 0.3 1 23 1039 1062 1039 1062 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.00043	0.048	15.3	0.4	2	23	148	170	147	170	0.97
2	20	0.14	16	7.3	6.0	1	23	316	339	316	339	0.94
3	20	3.7	4.2e+02	2.9	0.1	6	20	350	364	348	366	0.93
4	20	0.11	12	7.7	1.1	1	20	372	391	372	395	0.90
5	20	0.0018	0.21	13.3	2.6	2	23	463	484	462	484	0.98
6	20	0.016	1.8	10.4	0.1	1	23	502	523	502	523	0.98
7	20	0.013	1.5	10.6	0.4	2	23	527	548	526	548	0.96
8	20	4.8	5.4e+02	2.5	0.8	2	23	575	596	575	596	0.95
9	20	2.6	2.9e+02	3.4	1.7	1	23	611	634	611	634	0.83
10	20	0.13	15	7.4	0.1	2	23	647	668	647	668	0.96
11	20	6.3e-06	0.00071	21.0	6.6	1	23	703	725	703	725	0.98
12	20	0.00091	0.1	14.2	2.1	2	23	742	764	741	764	0.93
13	20	0.00063	0.071	14.7	0.7	1	23	781	804	781	804	0.95
14	20	0.011	1.2	10.9	0.1	2	23	817	839	816	839	0.93
15	20	0.00071	0.08	14.6	0.3	1	23	857	879	857	879	0.92
16	20	0.018	2	10.2	0.0	1	23	906	929	906	929	0.90
17	20	0.0072	0.81	11.4	1.0	2	23	939	960	939	960	0.95
18	20	0.0012	0.13	13.9	0.8	1	23	973	996	973	996	0.97
19	20	6.6e-07	7.4e-05	24.1	1.1	1	23	1003	1025	1003	1025	0.98
20	20	0.00063	0.07	14.8	0.3	1	23	1039	1062	1039	1062	0.96

Sequence Information

Coding Sequence: ATGTCTGAAGCTGAAATGGGCATTTACGCCCGCTGTTGCAGGCTTTGCCTGTCTGAAAACAAGGAAACATTGAATTTTGAGGCCTCGGACAAGGATCGTGCGTTCAGAGAGCGGATCCTAGCAGTGTTATCGATTGATATTAATGTCAACGATAAACTTTCCAAAATAGTATGCGACGTTTGCACACAAAAAGTTGAGAACTGGTGCGAGTTCAAGAAACTCTGTCAGAGAAATCAGACGACTCTTTCAGAATGGGCTAGCGAATGCATAGgggaaacgTCGTTTCAAGTAAAAGAAGAGGTAATTGAAGCTGATAATCCATTGGAAGACGATATAGAAATAGTGGCTGAAAACCTTACCGTAAAACTAGAACCAGTAGATTAtgaaaatcatgaaatttcgACCAATGGAGAGGCTGAAGAAAGTGTTGCTGAACCTGTCAAATGTCAAGATTGCGGCCAGgaatttgaaaagaaaaatgaATTGGACGAACACCGAAAAACTGCCCATGAAATGGAAACAGAAGAGATCCCGGCTGTAAACAATATAAGAAGATCATCCGAACAGAATCACTCGGAAAAAATCCAATTCGCAGCCGGCCTAAAGCTTATAAAAAGCGACGCGACCCCCATCGAAATGGAAAGTCTTTCTCCCCTGGAAAACAGCTACATCGAAAAGTGCAAGGCGATGGTAGAAATGTACCGGTCCTTGAAATGCGCTTGCCACCTTGCAACGCATCCCAACCTGAAAGGGTTGTTGTCCCATCTCAGATCCGTCAAGATTTGGTTTCCTGTTTTTACTTGCTACAACTGCATGATCACTTTCGTCGACCGATCCTCGAGCGGGAAGCACATACACAAATGCCCCAACAAGAATCTGGACACGCTGGTGAAATTGTCGAATCTGAAGAAAAGGAGCACCCTGAAGACCAGAATATATCAGAACTATAGGTGTACGAAATGTAGATTCATATTCACGTTTCACGAAGATTTCTGCAAACATATCGACGAGGAGCATTCGGACGAGGTGGGGCCTTATAATTGCTCGTGTCAACAGTCTTTTGATTCTCTGGAAGACTACAAGGATCACATATACGTTTCGTGCTTGGTGGAATATTACTGTGACATTTGTAATATTGCCGTTAGAACTTTAAAGGAATTCATTCATCATGCCGTGCATCAGCACGATAAGTCCGAAGGATTCGCCCTGATCCAAGAAGACAATTATAAGAAAAGGACGTTCCATAAGGTGGAACCCAGGGAGAACAAAGAAATATTGGGGAAGAGGAGGAGTTCGACTTACGGTAGGGCACTGAATATCGATCAAGCCGAGGACGAGGGTCAACTAAGTCCTAAATATTCCAAAAGTAGCCGAAATATCCCAACCCAATGTCCGCAGTGCGACAAGGTGTACTCCTGTCAAGCTAACATGTTGAGACACTTCCGAACGCATCAAGGAATCAAGCAGGAAAAACCTGAAACCGAAGATATGGACACCTGCTTCTACAGATGCCCGGATTGCCAGATTATGTACAACGCGGACGATTGGGAATCGCACAAACAGTCCCACGAGAACCTCAGTTGTTCCGAATGCGAGAAGGTGTTCTTGTTCCAAACCGAGCTGGAGCAACATCGGGTCacccatttaaatttgaaggtaTACAGGGACTCTAAGACGCATTCCTACAAAAGCACCATGTTGAGCCCGGATTCGAGGTTGCCCTATTGCGACGTATGCAATATTCTCTGCGAAAATTTCGAGGACTTGGACAGTCATAAACTTTCACATGAAGATTTAGAGGAGGAAGGGGTACCGATAGAAATTTCGAAGTATTCTTGTGCTACGTGCAATAAGCACTTTTTAACTTACGGAGAGTACAGCGAACACAACGCGAAGTTGCACACCGATAGGCAGACTACCAGCAACGTCTATCCTAGACAATGTGACGAGTGTGAGAAGGTGATAACGAGCGGTTCTGCATTTGCGAGTCATAAAGCGATGCACAGAAGGTTGAGGGATGAGTCGCAAAGGATTTCATCAGGTCCCGAGTCTCCGTTGGAGAGACCAAAATCCAGAAAGTCTGCGAATCAAGAAGACGAGGACTACCACACGTGTAAAAGATGCTTCAAAGTATTTTCCAATAAGTataatttgaagcaacatatgaAAATGCACGGAATCAACATGAATACCAGCAGAACATCAAAGTCTCCCAAAAAATTGTCTTGTCATAAATGCCATTTAACGTTTGGAAATAGTGAATCGCTGAACTCCCACATCGAGGAAGAACACGACGATATGCCAGATTTGGCTGAAGAATTTAATAACGAGCCCTACATTTTCACATGCGATGTATGCGTACAGACGTTCTCCACTAAGGTTGCTCTTATCCAACATAAAACAAGGCAGCATGCACAAGAGGCTGGACCGTCGAATAGATTTGTCACATATTGTAAGTACTGTAAGATTGGATTCGAAACATCAGTTGCCTTGGACGATCACATGGCCCAGGCTCACGCGGAAATGTCTGTAAAGCCGAGGACTCCCAAAAATAACCCGAACAAACCATTTTCGTGCAAATTATGCAACAAATCTTTCTCTTCGCAGCCAGCAATGTATGCCCATGTGGGTTGGCATAAGCGCACTAATAATGAAGGACCTTTGACGTCGCAGGTGAAAAAACCAGTAGGGCAAAATAAATATAGACGTGCCGAATTTGAATGTAACATTTGCGGTAAGGAACTACCTAACGATGTGGCACTCAAGATACATGCAATAGAGAAACACGGGAACGCGGCAGCTCTCTTGACTCCCAAATGTGAACCGTGCAACCAAGAATTCAAATCTCGCACCGAATACGAGAACCATATGAAACTGcacgaaattgttgaaaatcagAAAGGTCAGAAAGTAACTTTCTCTTGCCAGTTTTGCTCAGCGTCATTCAACAAGACTGAAACTTTGCAGGCGCATATTAAAATTAGCCATCCTACCATCACGCAGGAATTCAAATGTCCGCATTGCGGAAGAACTTTTGACAAGCAAGCGGCACTAACTAATCATGTGAAAGTTCATGAGAAGCAGAGATCATCAGTTGGAAGCCCCAAACCATTGTTCTTCTGTTCAATTTGTAACATGGGTTTTAATGTACCAAAGGATTTGAGAACGCATACTATAACTGCTCACCCTTTCTGA
Protein Sequence: MSEAEMGIYARCCRLCLSENKETLNFEASDKDRAFRERILAVLSIDINVNDKLSKIVCDVCTQKVENWCEFKKLCQRNQTTLSEWASECIGETSFQVKEEVIEADNPLEDDIEIVAENLTVKLEPVDYENHEISTNGEAEESVAEPVKCQDCGQEFEKKNELDEHRKTAHEMETEEIPAVNNIRRSSEQNHSEKIQFAAGLKLIKSDATPIEMESLSPLENSYIEKCKAMVEMYRSLKCACHLATHPNLKGLLSHLRSVKIWFPVFTCYNCMITFVDRSSSGKHIHKCPNKNLDTLVKLSNLKKRSTLKTRIYQNYRCTKCRFIFTFHEDFCKHIDEEHSDEVGPYNCSCQQSFDSLEDYKDHIYVSCLVEYYCDICNIAVRTLKEFIHHAVHQHDKSEGFALIQEDNYKKRTFHKVEPRENKEILGKRRSSTYGRALNIDQAEDEGQLSPKYSKSSRNIPTQCPQCDKVYSCQANMLRHFRTHQGIKQEKPETEDMDTCFYRCPDCQIMYNADDWESHKQSHENLSCSECEKVFLFQTELEQHRVTHLNLKVYRDSKTHSYKSTMLSPDSRLPYCDVCNILCENFEDLDSHKLSHEDLEEEGVPIEISKYSCATCNKHFLTYGEYSEHNAKLHTDRQTTSNVYPRQCDECEKVITSGSAFASHKAMHRRLRDESQRISSGPESPLERPKSRKSANQEDEDYHTCKRCFKVFSNKYNLKQHMKMHGINMNTSRTSKSPKKLSCHKCHLTFGNSESLNSHIEEEHDDMPDLAEEFNNEPYIFTCDVCVQTFSTKVALIQHKTRQHAQEAGPSNRFVTYCKYCKIGFETSVALDDHMAQAHAEMSVKPRTPKNNPNKPFSCKLCNKSFSSQPAMYAHVGWHKRTNNEGPLTSQVKKPVGQNKYRRAEFECNICGKELPNDVALKIHAIEKHGNAAALLTPKCEPCNQEFKSRTEYENHMKLHEIVENQKGQKVTFSCQFCSASFNKTETLQAHIKISHPTITQEFKCPHCGRTFDKQAALTNHVKVHEKQRSSVGSPKPLFFCSICNMGFNVPKDLRTHTITAHPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01024307;
90% Identity: -
80% Identity: -