Mdil014900.1
Basic Information
- Insect
- Megalocaria dilatata
- Gene Symbol
- -
- Assembly
- GCA_034642435.1
- Location
- CM067857.1:2695015-2704286[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.073 8.2 8.3 0.0 5 21 127 143 126 144 0.92 2 11 0.48 54 5.7 0.6 2 23 151 172 150 172 0.95 3 11 4.3e-05 0.0049 18.4 0.5 3 23 180 200 178 200 0.98 4 11 0.00013 0.014 16.9 0.1 1 23 207 229 207 229 0.97 5 11 1.3e-05 0.0014 20.1 3.0 1 23 242 265 242 265 0.95 6 11 0.0077 0.87 11.3 1.2 1 23 278 301 278 301 0.97 7 11 9.8e-06 0.0011 20.4 0.6 1 23 308 330 308 330 0.98 8 11 4e-07 4.5e-05 24.8 0.5 1 23 336 358 336 358 0.97 9 11 7.8e-06 0.00087 20.8 5.9 1 23 364 387 364 387 0.97 10 11 3.2e-06 0.00036 22.0 1.4 1 23 393 415 393 415 0.99 11 11 2.4e-05 0.0026 19.2 1.0 1 23 422 444 422 444 0.98
Sequence Information
- Coding Sequence
- ATGATTGCTCAGGAATTTGGTCAACATATGGAACAAGAATTACCAGAAATGGGCCATATAAAAATGGAGATTGAAAATCAAGATGAAGAATATATATCACAAATGGCCTCAGGAGAAATGCAAGATCAAGATGAATTAGAATTAAAGTATGTCAAACAAAATGGGGATGAAGAAGAACAGCAAGGATATTGGATGCAAGGCGCTGATGGAAACCATgTTGATCAAGCAGATGGACAGTATGAAAGTTTCATTCAAAATGTGAAAGTATTAAATCCAATGCAATTTGCTGATGGTACATATGTTGAGGAAAATACTCAAGAAGGAGGAGATCAATATGAAACAATCGAATTCGTTGATGACGTAAACTATGTTGATGAGGTGTGCAGAACGGCTTTTACCCAGGTTTCAGATCTGCGGCAACACTATAAAGAAAATTTGGACACCCATTTGACATGTCACATTTGCCTTGAAAAATTCCTCAACTTGCCTGAACTTGATGAACATCTGAAACAGCACGAGAGCAATAAGCCGTTCGGATGCGAAATTTGCGGTCTCAGGTTTAATCTACAAGCGAACTTTGAGCGTCACCTTAAGAAACATACTGAAAGTCAGACACTCTACAAATGTCAGATGTGTCCTAAAGtctTTAGTGACGAAGCCACCGTAATAGAACATGAGAAACTTCACGACACCATTCAGGAATTGATCGATGTAGATAGAAACCATCATTGTGAGGAATGTGGAAAGGTATTCACAACTGCTGGGTTCTTGAAGAAACACGTGGAACGCTTTCATCTTGGTCTAGAGTTCACCAAGAATCAGCGTATCCCGTTCGAATGTGAGCTTTGCGGAAAAATCCTGTCCTGCAAGGCTACCCTGTACAGTCACATGAAAAATGTTCATGAAAAAACCCAGAAAATGTACAGTTGCGAAATTTGCGGCAAAGTGCTCAAGACAAAAACATCTTTGGAGTTACATACCAATTATCATAATGGAAACTGTCCCTACAAGTGTAACATCTGCGGTAAGGCCTTCACCAATGCAACAACACTCAAGAGCCATTCTCTGATTCATACCAACGAAAGACCTCATGAATGTCAAGTGTGCCACAAGACCTTCAAACAGAAACCTCATTTGACTACTCATATACTGACTATTCATACAGCCCTGAAACTGTATAAATGCGAATTCTGCGAGAAAACATTTGCTCTGAAGGGCAATTTATCTCAACATCTAAAGACTCATACAGGATGTGACTCACCCTATGTATGCACAGTTTGTAATAAGGCATTTTACTTTGCCAGTAGGTTGAGGAAACATGAAAAGATacatatgaaacagtaa
- Protein Sequence
- MIAQEFGQHMEQELPEMGHIKMEIENQDEEYISQMASGEMQDQDELELKYVKQNGDEEEQQGYWMQGADGNHVDQADGQYESFIQNVKVLNPMQFADGTYVEENTQEGGDQYETIEFVDDVNYVDEVCRTAFTQVSDLRQHYKENLDTHLTCHICLEKFLNLPELDEHLKQHESNKPFGCEICGLRFNLQANFERHLKKHTESQTLYKCQMCPKVFSDEATVIEHEKLHDTIQELIDVDRNHHCEECGKVFTTAGFLKKHVERFHLGLEFTKNQRIPFECELCGKILSCKATLYSHMKNVHEKTQKMYSCEICGKVLKTKTSLELHTNYHNGNCPYKCNICGKAFTNATTLKSHSLIHTNERPHECQVCHKTFKQKPHLTTHILTIHTALKLYKCEFCEKTFALKGNLSQHLKTHTGCDSPYVCTVCNKAFYFASRLRKHEKIHMKQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -