Mrot001240.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile rotundata
Gene Symbol
-
Assembly
GCA_000220905.1
Location
NW:626319-645622[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 8.4e-05 0.0052 16.4 0.9 2 23 190 211 189 211 0.91
2 6 1.8e-05 0.0011 18.5 0.4 1 23 217 239 217 239 0.97
3 6 6.6e-06 0.00041 19.9 2.3 1 23 245 267 245 267 0.99
4 6 2e-05 0.0013 18.3 4.4 1 23 273 295 273 295 0.97
5 6 0.0013 0.078 12.7 1.5 1 21 301 321 301 324 0.85
6 6 3.4e-05 0.0021 17.6 0.3 1 23 332 355 332 355 0.92

Sequence Information

Coding Sequence
ATGCGCGAACCGATTTGGTACCGTCCCAAACGATCCCTCGATCGATGCGAATCAGGCCGCGAGACGTCCACGTGGAAAGTGGCTCCAAGCTGTGAAATGTCGCAGAATAACCTGCTGCAAGGATACAACTGGGAGACCCAGTACGAGGATCCGCAGGTGCAATTCACTCGTTCTATTCCGGACGAGGTTATCAGTGTTTACGAAGTTTACGTAAAGGAAGAGAACTCAGGACCTGAAAACCGAAACGACGTGACAGTCGTACCAAATTTACAATCCACAAATGATCACCAATTAAttcaaGGTGACTGCATGAGCCTGGATGTAGCGATAGATTCCGAAGTAATTAATATCGACAACACCGTGGCGAAATTTCTGAACAAAGATGCGTTCAAATACAAAATCGTCGATCAAAGTGTCAACACTACGGACAACGTTATGGTGTACTCGGACCCCGTGGTTGAGCGGCCATCTTCTTCCGCCACGCACCTCATCGACAAAGATGACCCCCGTTCCAAACTCCATTTTGTCAAGTATCTGAAACGGGACGGTAAAACGCTGAAAAtctgggaatgtggaatttGTTCCAAGGAGTTCCGGCATCAGTACACGTTGATGAGACACCTGCCAACGCACACCGACGAGAGGAACTTTAAATGCGAGGCTTGTGGCAAAGCTTTCCGCCAATTGTCGACACTGAGCCAACACAAAGCGATACACAGCGACGCTAGGCCTTACGTCTGTGAATTTTGCAAGAAGACTTTCAACAGaGTGTCCACGCTGATATCTCACCGCAAAACACACTCCGAACACAAGCCCCACAAGTGTCAAGTTTGCGGAAAAGGATTTCATCAAAAGgGCAATTTGAGAAACCACGTGTTTACCCATACGAACGAGAGGCCGTATAAATGCGAGCTTTGCGGCAAAGGCTTCAATCAGATGTCGAATTTGGTCTGCCACAAGGTCAAAGCGCATGCACACGCGGAGAAAATGCAGTACGTGTGCGGAATCTGCGGCAAAGAGTTCCCGCGTCGGTTCGCTTTGAGATCGCACGAGGAGTACAAGCACGGCATCAAATATCGACATCCAACCACGCCGCAGCCGGGAATCAACGATCCGAACGTTATAAGAAAtaaGAATGTTAGGATCGTGCAGCTGCCCAACGGGGATCGTAATCAGACCATTGATGTCAGAGACAAAGATCCTCTTATCTCGCTCTCGAACTCTCTGTCACCGAAGTCGGACATGATGGAATCAGTAGTGATCGACAAAATCGACACAAAAGCAATGGACATGGCGCTCCTGGAGGGTCAAACGCCATTCGCCCTCTTCAAACCCGCCAAAGGAATTCCAGTTCTCGTCAAGATCTCTCCTACAGGAACCCACAAAAACATCCTGACACCCGCCACAGCGGAAGATCTACGAATGGCGGGCAAGATGAGCCTAAGTCCAACCATCACATCCGACGCGGACCGGGTCAAAGCTGTCCAAGTGAAAGTACCCGTGGTAGCCACTGTCATTCAGAACATAGATCCTGATGGAAAGATGAATTTCATCGTGGAACCGCCTGGACCAGAAAATGAGCATGAGAGTCTGGTCACGGCATTGGATTCTCAGTTCACGTACACCGAGCCCCATAGGAACGAGCCAGATCGTCAGAATGGTCCTGTTGTGTCTACGTCGATGGAGGATTGCAACGAGTTGCTGGAACTGGCCGCCCAGGGTGGAATACAATTCGTGAGAGCCACCGAAGATGGGCGTTATGAGGTGATGACAAACAGCGAGGCGAGAGATCTGATGGCGCAGAATTCGCACGATGTGACAATTCTGGACGGCGATGAAGCGGACGCGATCAATGTGGTGAATATGCGTGGCAACGGGGAAGTCATCATCGGGGATTCCGATAATCAGATCATGGTACTCGATTCCGGCACGACGCAGAAATCCATGTCGATGGATGGCATCGAGATCCTGGAGGACAAGGACATCCGAATCCTCGACAGCAAGAGCCTCGACGACCGCTTCGTGGACGGCATTAGCTTCCTCTCGCAGTCCAAAATCGATGATTTGATTCTTGGCCCGAAACCGTTGACCATTGAGAGCGGAGTCAACGTTGCTGAGGACGAGACTATAGGAGTGCCATCGAGCCAGCAAGAGTTAACAAACATCCTCAGTCATCGAAGCGACATATCGACTCTATCGACAACGTCTCATCACGCCATATCGTCTCTTTTAATGAAGAATCACACTCCAATGTCGATTTTAAATGATACGTTGCCATACTTGAAGAGTAATACAAGCTTGACTGAGGATTTGAACATCCTTAATAGTTCTAGCATGGATGATCATCATTCGGTGTATGATACTAAAATGAAGTTACCGTCTGTGTTTGATGATAGTGAAGGGGATGCTGGGTTGATACCTATTACTCAGTCGGATATGAAGATTCTGGGGTCGATCGCTTCGAATCCGAAGGTCCTGGGCAGTAAACCGAATTGTCTCTCGTCATCGAAACTGTTTTCTGGTCTCGGCGAGGTGAAGATTCTGGGTCCAAAGAACCATAACCAAGAGCTGATGGTGTCCCAGTATCAAGAGTCGAAATTACTTAGCCCGTACGAGCAGTTCTTGAAGAGCACCGCCTCGAACATGAACGGCTGCGACACCAACGCCGTGAACGCTTCCGGTGGATGCAGGAAGGAGGTAAAGATCCTGGGCAAGAAGTTGGGAACAGGTATTATTACCAGCACGGTGGAGGGCAACGTTGTGGAAGTAGTCGAGGAGAAAACTAAGCTGTTAATGGACGGCGTAGGATCCCTCTGCAACAGCACAGACAGCACCGTGATATCGTCTCCTCGTTTAGATCGACAGATCCCGGAAAATGGCGTGCCAGACAGTTTCTTGCTTCAAGCCTGTAGCCCGTGTGGTTctgattttctgaatttcgaGAACCGTTTGAAGGACACTTCGCCGGCCGGCCATTTTGAACGAACACAAAAGGATTCCACAGACTTTAGCTCCACCGGACTGCCGGATCTCGATTGA
Protein Sequence
MREPIWYRPKRSLDRCESGRETSTWKVAPSCEMSQNNLLQGYNWETQYEDPQVQFTRSIPDEVISVYEVYVKEENSGPENRNDVTVVPNLQSTNDHQLIQGDCMSLDVAIDSEVINIDNTVAKFLNKDAFKYKIVDQSVNTTDNVMVYSDPVVERPSSSATHLIDKDDPRSKLHFVKYLKRDGKTLKIWECGICSKEFRHQYTLMRHLPTHTDERNFKCEACGKAFRQLSTLSQHKAIHSDARPYVCEFCKKTFNRVSTLISHRKTHSEHKPHKCQVCGKGFHQKGNLRNHVFTHTNERPYKCELCGKGFNQMSNLVCHKVKAHAHAEKMQYVCGICGKEFPRRFALRSHEEYKHGIKYRHPTTPQPGINDPNVIRNKNVRIVQLPNGDRNQTIDVRDKDPLISLSNSLSPKSDMMESVVIDKIDTKAMDMALLEGQTPFALFKPAKGIPVLVKISPTGTHKNILTPATAEDLRMAGKMSLSPTITSDADRVKAVQVKVPVVATVIQNIDPDGKMNFIVEPPGPENEHESLVTALDSQFTYTEPHRNEPDRQNGPVVSTSMEDCNELLELAAQGGIQFVRATEDGRYEVMTNSEARDLMAQNSHDVTILDGDEADAINVVNMRGNGEVIIGDSDNQIMVLDSGTTQKSMSMDGIEILEDKDIRILDSKSLDDRFVDGISFLSQSKIDDLILGPKPLTIESGVNVAEDETIGVPSSQQELTNILSHRSDISTLSTTSHHAISSLLMKNHTPMSILNDTLPYLKSNTSLTEDLNILNSSSMDDHHSVYDTKMKLPSVFDDSEGDAGLIPITQSDMKILGSIASNPKVLGSKPNCLSSSKLFSGLGEVKILGPKNHNQELMVSQYQESKLLSPYEQFLKSTASNMNGCDTNAVNASGGCRKEVKILGKKLGTGIITSTVEGNVVEVVEEKTKLLMDGVGSLCNSTDSTVISSPRLDRQIPENGVPDSFLLQACSPCGSDFLNFENRLKDTSPAGHFERTQKDSTDFSSTGLPDLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01169399;
90% Identity
iTF_00964680;
80% Identity
-